The dynamics of lipid molecules in lipid bilayers and monolayers was resolved using fluorescence techniques. Notably, both types of systems were studied at equal area per lipid, allowing us to evaluate the magnitude of interleaflet coupling across multiple lipid species with differing acyl chains. Atomistic molecular dynamics simulations were used to extract parameters for the theoretical treatment of the phenomena, as well as to study the degree of acyl chain interdigitation at the membrane midplane for the various lipid species.
A collaboration with the group of Prof. Salvatore Chiantia from University of Potsdam.
Titas Mandal, Nadine Brandt, Carmelo Tempra, Matti Javanainen, Balázs Fábián, and Salvatore Chiantia.
A comparison of lipid diffusive dynamics in monolayers and bilayers in the context of interleaflet coupling.
Now out in BBA–Biomembranes.