Publications

2021

  1. Jacome Sanz, D, Raivola, J, Karvonen, H, Arjama, M, Barker, H, Murumägi, A et al.. Evaluating Targeted Therapies in Ovarian Cancer Metabolism: Novel Role for PCSK9 and Second Generation mTOR Inhibitors. Cancers (Basel). 2021;13 (15):. doi: 10.3390/cancers13153727. PubMed PMID:34359627 PubMed Central PMC8345177.
  2. Murumägi, A, Ungureanu, D, Arjama, M, Bützow, R, Lohi, J, Sariola, H et al.. STRN-ALK rearranged pediatric malignant peritoneal mesothelioma – Functional testing of 527 cancer drugs in patient-derived cancer cells. Transl Oncol. 2021;14 (4):101027. doi: 10.1016/j.tranon.2021.101027. PubMed PMID:33530027 PubMed Central PMC7851186.

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2020

  1. Karvonen, H, Arjama, M, Kaleva, L, Niininen, W, Barker, H, Koivisto-Korander, R et al.. Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness. Cell Death Dis. 2020;11 (9):790. doi: 10.1038/s41419-020-03009-4. PubMed PMID:32989221 PubMed Central PMC7522257.
  2. Sheetz, JB, Mathea, S, Karvonen, H, Malhotra, K, Chatterjee, D, Niininen, W et al.. Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Mol Cell. 2020;79 (3):390-405.e7. doi: 10.1016/j.molcel.2020.06.018. PubMed PMID:32619402 PubMed Central PMC7543951.

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2019

  1. Karvonen, H, Barker, H, Kaleva, L, Niininen, W, Ungureanu, D. Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways. Cells. 2019;8 (8):. doi: 10.3390/cells8080812. PubMed PMID:31382410 PubMed Central PMC6721603.
  2. Tudor, Ș, Minciună, C, Lăcătuş, M, Gavrilă, D, Manciu, S, Ungureanu, D et al.. Transanal Total Mesorectal Excision – A Case Report. Chirurgia (Bucur). ;114 (2):278-283. doi: 10.21614/chirurgia.114.2.278. PubMed PMID:31060661 .
  3. Karvonen, H, Perttilä, R, Niininen, W, Hautanen, V, Barker, H, Murumägi, A et al.. Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting. Oncogene. 2019;38 (17):3288-3300. doi: 10.1038/s41388-018-0670-9. PubMed PMID:30631148 .

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2018

  1. Karvonen, H, Perttilä, R, Niininen, W, Barker, H, Ungureanu, D. Targeting Wnt signaling pseudokinases in hematological cancers. Eur J Haematol. 2018;101 (4):457-465. doi: 10.1111/ejh.13137. PubMed PMID:29989208 .
  2. Karvonen, H, Summala, K, Niininen, W, Barker, HR, Ungureanu, D. Interaction between ROR1 and MuSK activation complex in myogenic cells. FEBS Lett. 2018;592 (3):434-445. doi: 10.1002/1873-3468.12966. PubMed PMID:29292499 .

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