Publications

2024

  1. Samaniego, EA, Dabus, G, Meyers, PM, Kan, PT, Frösen, J, Lanzino, G et al.. Most Promising Approaches to Improve Brain AVM Management: ARISE I Consensus Recommendations. Stroke. 2024;55 (5):1449-1463. doi: 10.1161/STROKEAHA.124.046725. PubMed PMID:38648282 .
  2. Glavan, M, Jelic, A, Levard, D, Frösen, J, Keränen, S, Franx, BAA et al.. CNS-associated macrophages contribute to intracerebral aneurysm pathophysiology. Acta Neuropathol Commun. 2024;12 (1):43. doi: 10.1186/s40478-024-01756-5. PubMed PMID:38500201 PubMed Central PMC10946177.
  3. Denorme, F, Frösen, J, Jouppila, A, Lindgren, A, Resendiz-Nieves, JC, Manninen, H et al.. Pretreatment with a dual antiplatelet and anticoagulant (APAC) reduces ischemia-reperfusion injury in a mouse model of temporary middle cerebral artery occlusion-implications for neurovascular procedures. Acta Neurochir (Wien). 2024;166 (1):137. doi: 10.1007/s00701-024-06017-x. PubMed PMID:38485848 PubMed Central PMC10940479.
  4. Frösen, J, Räisänen, S, Lindgren, A. Reply to the letter by Yin et al. ‘Reevaluating the impact of antihypertensive medication on intracranial aneurysm formation: a call for clarification and further study’. Eur J Neurol. 2024; :e16272. doi: 10.1111/ene.16272. PubMed PMID:38445774 .
  5. Raatikainen, E, Kiiski, H, Kuitunen, A, Junttila, E, Huhtala, H, Kallonen, A et al.. Increased blood coagulation is associated with poor neurological outcome in aneurysmal subarachnoid hemorrhage. J Neurol Sci. 2024;458 :122943. doi: 10.1016/j.jns.2024.122943. PubMed PMID:38422781 .
  6. Tarkiainen, J, Pyysalo, L, Hinkka, T, Pienimäki, JP, Ronkainen, A, Frösen, J et al.. Stability of infundibular dilatations: a single center follow-up study and systematic review of the literature. Acta Neurochir (Wien). 2024;166 (1):48. doi: 10.1007/s00701-024-05890-w. PubMed PMID:38286939 PubMed Central PMC10824818.

Search PubMed

2023

  1. Tarkiainen, J, Hovi, V, Pyysalo, L, Ronkainen, A, Frösen, J. Correction to: The clinical course and outcomes of non-aneurysmal subarachnoid hemorrhages in a single-center retrospective study. Acta Neurochir (Wien). 2023;165 (12):3707. doi: 10.1007/s00701-023-05834-w. PubMed PMID:37878129 PubMed Central PMC10739382.
  2. Tarkiainen, J, Hovi, V, Pyysalo, L, Ronkainen, A, Frösen, J. The clinical course and outcomes of non-aneurysmal subarachnoid hemorrhages in a single-center retrospective study. Acta Neurochir (Wien). 2023;165 (10):2843-2853. doi: 10.1007/s00701-023-05767-4. PubMed PMID:37659045 PubMed Central PMC10542109.
  3. Natukka, T, Haapasalo, J, Kivioja, T, Rajala, L, Raitanen, J, Nevalainen, J et al.. Impact of Timing of Surgery and Adjuvant Treatment on Survival of Adult IDH-wild-type Glioblastoma: A Single-center Study of 392 Patients. World Neurosurg. 2023; :. doi: 10.1016/j.wneu.2023.07.008. PubMed PMID:37423335 .
  4. Laaksonen, M, Rinne, J, Rahi, M, Posti, JP, Laitio, R, Kivelev, J et al.. Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage-study protocol for a randomized clinical trial. Trials. 2023;24 (1):417. doi: 10.1186/s13063-023-07432-8. PubMed PMID:37337295 PubMed Central PMC10280919.
  5. Järvelin, P, Pekonen, H, Koivisto, T, Frösen, J. Recurrence of arteriovenous malformations of the brain after complete surgical resection. Kuopio University Hospital experience and systematic review of the literature. Neurosurg Rev. 2023;46 (1):99. doi: 10.1007/s10143-023-02001-8. PubMed PMID:37119280 PubMed Central PMC10148763.
  6. Hallikainen, J, Pessi, T, Vehkalahti, M, Suominen, AL, Pyysalo, M, Frösen, J et al.. Unlike severe periodontitis, caries does not associate with intracranial aneurysms or aneurysmal subarachnoid hemorrhage. Acta Neurochir (Wien). 2023;165 (1):169-175. doi: 10.1007/s00701-022-05406-4. PubMed PMID:36416942 PubMed Central PMC9840572.

Search PubMed

2022

  1. Hallikainen, J, Pessi, T, Vehkalahti, M, Suominen, AL, Pyysalo, M, Frösen, J et al.. Unlike severe periodontitis, caries does not associate with intracranial aneurysms or aneurysmal subarachnoid hemorrhage. Acta Neurochir (Wien). 2023;165 (1):169-175. doi: 10.1007/s00701-022-05406-4. PubMed PMID:36416942 PubMed Central PMC9840572.
  2. Frösen, J. Association of blood lipid levels with the risk of intracranial aneurysm formation and rupture calls for further studies: A commentary on the article by Zhang et al. Eur J Neurol. 2022;29 (10):2879-2880. doi: 10.1111/ene.15514. PubMed PMID:35861121 PubMed Central PMC9544045.
  3. Räisänen, S, Huttunen, J, Huuskonen, TJ, von Und Zu Fraunberg, M, Koivisto, T, Jääskeläinen, JE et al.. Risk factor management matters more than pharmaceutical cyclooxygenase-2 inhibition in the prevention of de novo intracranial aneurysms. Eur J Neurol. 2022;29 (9):2734-2743. doi: 10.1111/ene.15442. PubMed PMID:35678735 .
  4. Räisänen, S, Huttunen, J, Huuskonen, TJ, von Und Zu Fraunberg, M, Koivisto, T, Jääskeläinen, JE et al.. Use of antihypertensive medication and formation of de novo intracranial aneurysms. Eur J Neurol. 2022;29 (9):2708-2715. doi: 10.1111/ene.15430. PubMed PMID:35652754 .
  5. Frösen, J, Tarkiainen, J, Kelahaara, M, Pyysalo, L, Ronkainen, A. Reader Response: Substantial Within-Country Variation in the Incidence of Subarachnoid Hemorrhage: A Nationwide Finnish Study. Neurology. 2022;98 (17):733-734. doi: 10.1212/WNL.0000000000200509. PubMed PMID:35470266 .
  6. Salimi Ashkezari, SF, Mut, F, Slawski, M, Cheng, B, Yu, AK, White, TG et al.. Prediction of bleb formation in intracranial aneurysms using machine learning models based on aneurysm hemodynamics, geometry, location, and patient population. J Neurointerv Surg. 2022;14 (10):1002-1007. doi: 10.1136/neurintsurg-2021-017976. PubMed PMID:34686573 PubMed Central PMC9023610.

Search PubMed

2021

  1. Salimi Ashkezari, SF, Mut, F, Slawski, M, Cheng, B, Yu, AK, White, TG et al.. Prediction of bleb formation in intracranial aneurysms using machine learning models based on aneurysm hemodynamics, geometry, location, and patient population. J Neurointerv Surg. 2022;14 (10):1002-1007. doi: 10.1136/neurintsurg-2021-017976. PubMed PMID:34686573 PubMed Central PMC9023610.
  2. Hackenberg, KAM, Algra, A, Al-Shahi Salman, R, Frösen, J, Hasan, D, Juvela, S et al.. Correction to: Definition and Prioritization of Data Elements for Cohort Studies and Clinical Trials on Patients with Unruptured Intracranial Aneurysms: Proposal of a Multidisciplinary Research Group. Neurocrit Care. 2021;35 (3):924-926. doi: 10.1007/s12028-021-01346-6. PubMed PMID:34608597 .
  3. Keränen, S, Suutarinen, S, Mallick, R, Laakkonen, JP, Guo, D, Pawlikowska, L et al.. Cyclo-oxygenase 2, a putative mediator of vessel remodeling, is expressed in the brain AVM vessels and associates with inflammation. Acta Neurochir (Wien). 2021;163 (9):2503-2514. doi: 10.1007/s00701-021-04895-z. PubMed PMID:34185176 PubMed Central PMC8357659.
  4. Hallikainen, J, Pyysalo, M, Keränen, S, Kellokoski, J, Koivisto, T, Suominen, AL et al.. Systemic immune response against the oral pathogens Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans is associated with the formation and rupture of intracranial aneurysms. Eur J Neurol. 2021;28 (9):3089-3099. doi: 10.1111/ene.14986. PubMed PMID:34145948 .
  5. Salimi Ashkezari, SF, Mut, F, Chung, BJ, Robertson, AM, Frösen, J, Cebral, JR et al.. Analysis of hemodynamic changes from aneurysm inception to large sizes. Int J Numer Method Biomed Eng. 2021;37 (1):e3415. doi: 10.1002/cnm.3415. PubMed PMID:33205887 PubMed Central PMC8991439.
  6. Salimi Ashkezari, SF, Mut, F, Chung, BJ, Yu, AK, Stapleton, CJ, See, AP et al.. Hemodynamics in aneurysm blebs with different wall characteristics. J Neurointerv Surg. 2021;13 (7):642-646. doi: 10.1136/neurintsurg-2020-016601. PubMed PMID:33020208 PubMed Central PMC8294199.
  7. Salimi Ashkezari, SF, Detmer, FJ, Mut, F, Chung, BJ, Yu, AK, Stapleton, CJ et al.. Blebs in intracranial aneurysms: prevalence and general characteristics. J Neurointerv Surg. 2021;13 (3):226-230. doi: 10.1136/neurintsurg-2020-016274. PubMed PMID:32680877 PubMed Central PMC8294207.
  8. Hallikainen, J, Keränen, S, Savolainen, J, Närhi, M, Suominen, AL, Ylöstalo, P et al.. Role of oral pathogens in the pathogenesis of intracranial aneurysm: review of existing evidence and potential mechanisms. Neurosurg Rev. 2021;44 (1):239-247. doi: 10.1007/s10143-020-01253-y. PubMed PMID:32034564 PubMed Central PMC7850994.