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Internal Medicine Haemodynamics

The DYNAMIC study focuses on non-invasive measurement of haemodynamics.

Publications

2025

  1. Pekola-Kiviniemi, M, Tikkakoski, AJ, Koskela, JK, Tahvanainen, A, Mäkelä, S, Jääskeläinen, M et al.. Eight months of marathon school training reduced blood pressure, systemic vascular resistance and extracellular water volume. Sci Rep. 2025;15 (1):17639. doi: 10.1038/s41598-025-02357-5. PubMed PMID:40399484 PubMed Central PMC12095685.
  2. Bouquin, H, Suojanen, LJ, Koskela, JK, Pietilä, E, Choudhary, MK, Mustonen, JT et al.. High variability in the reproducibility of key hemodynamic responses to head-up tilt. Am J Physiol Heart Circ Physiol. 2025;328 (3):H387-H392. doi: 10.1152/ajpheart.00796.2024. PubMed PMID:39792204 .

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2024

 

  1. Suonsyrjä, N, Metso, S, Moilanen, E, Mustonen, J, Jaatinen, P, Pörsti, I et al.. Haemodynamics of hyperthyroidism: increased cardiac work and findings related to vasodilatation. Eur Thyroid J. 2024;13 (5):. doi: 10.1530/ETJ-24-0090. PubMed PMID:39356807 PubMed Central PMC11558968.
  2. Kokko, E, Viukari, M, Koskela, JK, Choudhary, MK, Matikainen, N, Mustonen, J et al.. Targeted Treatment Reverses Increased Left Cardiac Work in Unilateral vs. Bilateral Primary Aldosteronism. Am J Hypertens. 2024;37 (11):884-892. doi: 10.1093/ajh/hpae087. PubMed PMID:38985455 PubMed Central PMC11471835.
  3. Kokko, E, Choudhary, MK, Mutanen, A, Honkonen, M, Tikkakoski, A, Koskela, JK et al.. Volume overload is a major characteristic in primary aldosteronism: a 3-year follow-up study. J Hypertens. 2024;42 (6):1057-1065. doi: 10.1097/HJH.0000000000003696. PubMed PMID:38406920 PubMed Central PMC11064919.
  4. Bouquin, H, Koskela, JK, Tikkakoski, A, Honkonen, M, Hiltunen, TP, Mustonen, JT et al.. Differences in heart rate responses to upright posture are associated with variations in the high-frequency power of heart rate variability. Am J Physiol Heart Circ Physiol. 2024;326 (3):H479-H489. doi: 10.1152/ajpheart.00567.2023. PubMed PMID:38133619 PubMed Central PMC11219049.

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2023

 

  1. Choudhary, MK, Bouquin, H, Hytönen, J, Koskela, JK, Niemelä, O, Nevalainen, PI et al.. Blood Haemoglobin Concentration Is Directly and Independently Related with Pulse Wave Velocity, a Measure of Large Artery Stiffness. J Clin Med. 2023;12 (24):. doi: 10.3390/jcm12247623. PubMed PMID:38137695 PubMed Central PMC10743951.
  2. Bouquin, H, Koskela, JK, Tikkakoski, A, Honkonen, M, Hiltunen, TP, Mustonen, JT et al.. Differences in heart rate responses to upright posture are associated with variations in the high-frequency power of heart rate variability. Am J Physiol Heart Circ Physiol. 2024;326 (3):H479-H489. doi: 10.1152/ajpheart.00567.2023. PubMed PMID:38133619 PubMed Central PMC11219049.
  3. Penninkangas, RM, Choudhary, MK, Mangani, C, Maleta, K, Teivaanmäki, T, Niemelä, O et al.. Low length-for-age Z-score within 1 month after birth predicts hyperdynamic circulation at the age of 21 years in rural Malawi. Sci Rep. 2023;13 (1):10283. doi: 10.1038/s41598-023-37269-9. PubMed PMID:37355681PubMed Central PMC10290681.
  4. Värri, E, Suojanen, L, Koskela, JK, Choudhary, MK, Tikkakoski, A, Kähönen, M et al.. Ambulatory daytime blood pressure versus tonometric blood pressure measurements in the laboratory: effect of posture. Blood Press Monit. 2023;28 (4):199-207. doi: 10.1097/MBP.0000000000000651. PubMed PMID:37318783 PubMed Central PMC10309093.
  5. Taurio, J, Hautaniemi, EJ, Koskela, JK, Eräranta, A, Hämäläinen, M, Tikkakoski, A et al.. The characteristics of elevated blood pressure in abdominal obesity correspond to primary hypertension: a cross-sectional study. BMC Cardiovasc Disord. 2023;23 (1):161. doi: 10.1186/s12872-023-03150-w. PubMed PMID:36973671 PubMed Central PMC10045516.
  6. Taurio, J, Koskela, J, Sinisalo, M, Tikkakoski, A, Niemelä, O, Hämäläinen, M et al.. Urine sodium excretion is related to extracellular water volume but not to blood pressure in 510 normotensive and never-treated hypertensive subjects. Blood Press. 2023;32 (1):2170869. doi: 10.1080/08037051.2023.2170869. PubMed PMID:36708156 .

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2022

 

  1. Koskela, JK, Tahvanainen, A, Tikkakoski, AJ, Kangas, P, Uitto, M, Viik, J et al.. Resting heart rate predicts cardiac autonomic modulation during passive head-up tilt in subjects without cardiovascular diseases. Scand Cardiovasc J. 2022;56 (1):138-147. doi: 10.1080/14017431.2022.2079713. PubMed PMID:35652524 .
  2. Choudhary, MK, Penninkangas, RM, Eräranta, A, Niemelä, O, Mangani, C, Maleta, K et al.. Posture-Related Differences in Cardiovascular Function Between Young Men and Women: Study of Noninvasive Hemodynamics in Rural Malawi. J Am Heart Assoc. 2022;11 (5):e022979. doi: 10.1161/JAHA.121.022979. PubMed PMID:35195013 PubMed Central PMC9075090.
  3. Koskela, JK, Vääräniemi, K, Tahvanainen, AMH, Mustonen, J, Mäkelä, S, Tikkakoski, AJ et al.. Disparate Information Provided by Pulse Wave Velocity versus Other Measures of Aortic Compliance in End-Stage Renal Disease. Nephron. 2022;146 (1):11-21. doi: 10.1159/000518174. PubMed PMID:34515178 .

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2021

 

  1. Koskela, JK, Vääräniemi, K, Tahvanainen, AMH, Mustonen, J, Mäkelä, S, Tikkakoski, AJ et al.. Disparate Information Provided by Pulse Wave Velocity versus Other Measures of Aortic Compliance in End-Stage Renal Disease. Nephron. 2022;146 (1):11-21. doi: 10.1159/000518174. PubMed PMID:34515178 .
  2. Suojanen, LJ, Koskela, JK, Wilenius, M, Choudhary, MK, Hautaniemi, EJ, Viik, J et al.. Individual changes of central blood pressure in response to upright posture: different hemodynamic phenotypes. J Hypertens. 2021;39 (12):2403-2412. doi: 10.1097/HJH.0000000000002965. PubMed PMID:34269331 .
  3. Hamid, H, Kurra, V, Choudhary, MK, Bouquin, H, Niemelä, O, Kähönen, MAP et al.. Plasma uric acid is related to large arterial stiffness but not to other hemodynamic variables: a study in 606 normotensive and never-medicated hypertensive subjects. BMC Cardiovasc Disord. 2021;21 (1):257. doi: 10.1186/s12872-021-02072-9. PubMed PMID:34039285 PubMed Central PMC8152327.
  4. Oinonen, L, Tikkakoski, A, Koskela, J, Eräranta, A, Kähönen, M, Niemelä, O et al.. Parathyroid hormone may play a role in the pathophysiology of primary hypertension. Endocr Connect. 2021;10 (1):54-65. doi: 10.1530/EC-20-0446. PubMed PMID:33289696 PubMed Central PMC7923049.

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