Projects

Ongoing research:
Psychopharmacogenetics

Research material of schizophrenia patients on clozapine (n=236): Study of the connection between adverse symptoms and potentially related genetic polymorphisms. Research group: Esa Leinonen, Olli Kampman, Merja Viikki, Jari-Pekka Klemettilä, Anssi Solismaa, Terho Lehtimäki

Research material of depression patients receiving electrotherapy (n=119): Study of the connection between treatment response and potentially related genetic polymorphisms.
Research group: Esa Leinonen, Kaija Järventausta, Merja Viikki, Mervi Kautto, Terho Lehtimäki

Research material of depression patients on selective serotonin medication (n=101): Study of the connections between treatment response, temperament and potentially related genetic polymorphisms.
Research group: Esa Leinonen, Olli Kampman, Ari Illi, Merja Viikki, Kadri Andre, Terho Lehtimäki

The genetic background of depression and simultaneous substance abuse problems and temperament (n=240): Study of the connections between the treatment response achieved through motivating interviews and the behaviour activation model, temperament characteristics and potentially related genetic polymorphisms of depression or depression and simultaneous substance abuse problems.
Research group: Olli Kampman, Onni Niemelä, Antti Koivukangas, Vesa Paavonen, Esa Leinonen, Terho Lehtimäki

Biological markers related to the treatment and adverse effects of schizophrenia and depression

Research material of schizophrenia patients on clozapine (n=236): A study of the connection between biological markers related to cytokine and other metabolic disorders and potentially related genetic polymorphisms, and the adverse effects of clozapine.
Research group: Esa Leinonen, Olli Kampman, Niko Seppälä, Merja Viikki, Jari-Pekka Klemettilä, Terho Lehtimäki

Research material of depression patients receiving electrotherapy (n=30): A study of the connection between the effects of certain cytokines and growth factors, and the treatment response of electrotherapy and other clinical parameters.
Research group: Esa Leinonen, Kaija Järventausta, Kai Lehtimäki, Annamari Sorri, Hanna-Mari Alanen, Olli Kampman

Other ongoing research:

Patients treated at geriatric psychiatry wards (n=89, n=78): A study of the treatment response and ability to function of patients suffering from memory disorders, who have undergone psychiatric hospital treatment due to severe behavioural disorders in two different time periods.
Research group: Esa Leinonen, Hanna-Mari Alanen, Olli Kampman, Anneli Pitkänen, Kirsti Suontaka-Jamalainen

Prognosis of elderly patients suffering from schizophrenia (n=8,792): A study of the mortality, use of psychiatric medication and relapse risk of elderly patients suffering from schizophrenia, based on register material.
Research group: Esa Leinonen, Tiina Talaslahti, Hanna-Mari Alanen, Helinä Hakko, Olli Kampman, Unto Häkkinen, Matti Isohanni