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Psychiatry

Publications

2026

  1. Mustonen, A, Niemelä, S, Denissoff, A, Forti, MD, Tanskanen, A, Mittendorfer-Rutz, E et al.. Optimizing antipsychotic dosing for relapse prevention in cannabis-induced psychosis: A nationwide cohort study. Psychiatry Res. 2026;358 :116966. doi: 10.1016/j.psychres.2026.116966. PubMed PMID:41581246 .
  2. Mikkonen, K, Lintula, SJ, Rosenström, T, Lahti, J, Helminen, EE, Saarni, SI et al.. Associations of prior treatment, waiting time, symptom severity, and session frequency with symptom change in CBT for depression and anxiety in primary care. J Affect Disord. 2026;400 :121225. doi: 10.1016/j.jad.2026.121225. PubMed PMID:41577045 .
  3. Awaga-Cromwell, MM, Ozochi, CA, Kaija, A, Isaacs, ES, Garg, T, Okonkwo, CC et al.. Cyclic di-adenosine monophosphate as a potential regulator of sporulation and solventogenesis in Clostridium beijerinckii: a hypothesis. World J Microbiol Biotechnol. 2026;42 (1):26. doi: 10.1007/s11274-025-04768-y. PubMed PMID:41483086 .
  4. Käärid, K, Marshall, E, Honor, R, Sorensen, R, Murphy, P, Crane, J et al.. Association between Elevated Pre-pregnancy BMI and Outcomes of Labour Induction: A Population-Based Retrospective Cohort Study. J Obstet Gynaecol Can. 2026;48 (1):103175. doi: 10.1016/j.jogc.2025.103175. PubMed PMID:41308918 .
  5. Mylläri, S, Saarni, SE, Joffe, G, Ritola, V, Stenberg, JH, Rosenström, TH et al.. Machine learned text topics improve drop-out risk prediction but not symptom prediction in online psychotherapies for depression and anxiety. Psychother Res. 2026;36 (2):387-402. doi: 10.1080/10503307.2025.2473921. PubMed PMID:40101214 .

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2025

  1. Käärid, K, Marshall, E, Honor, R, Sorensen, R, Murphy, P, Crane, J et al.. Association between Elevated Pre-pregnancy BMI and Outcomes of Labour Induction: A Population-Based Retrospective Cohort Study. J Obstet Gynaecol Can. 2026;48 (1):103175. doi: 10.1016/j.jogc.2025.103175. PubMed PMID:41308918 .
  2. Leijala, J, Kampman, O, Gunnar, T, Suvisaari, J. Treatment adherence in first-episode psychosis: A one-year follow-up study comparing self-reported adherence, pharmacy refill data, and therapeutic drug monitoring. Psychiatry Res. 2025;354 :116780. doi: 10.1016/j.psychres.2025.116780. PubMed PMID:41176920 .
  3. Rask, SM, Solismaa, A, Ahola-Olli, A, Molden, E, O’Connell, KS, Lyytikäinen, LP et al.. Meta-analyses of clozapine, norclozapine levels and their ratio across three genome wide association studies. Transl Psychiatry. 2025;15 (1):431. doi: 10.1038/s41398-025-03649-0. PubMed PMID:41136382 PubMed Central PMC12552505.
  4. Seittu, HA, Falk, T, Bhatnagar, K, Saarni, SE. Therapists’ Role in Patient Adherence to Internet-Based Cognitive Behavioral Therapy: Qualitative Study. J Med Internet Res. 2025;27 :e71852. doi: 10.2196/71852. PubMed PMID:40929730 PubMed Central PMC12422719.
  5. Hyvönen, S, Saarikivi, A, Mälkönen, J, Solasaari, T, Korpela, K, de Vos, WM et al.. The association of maternal and infant early gut microbiota with respiratory infections in infants. Pediatr Res. 2025; :. doi: 10.1038/s41390-025-04326-0. PubMed PMID:40836109 .
  6. Ahti, J, Haaki, W, Kieseppä, T, Suvisaari, J, Niemelä, S, Suokas, K et al.. Suicidal acts and thoughts among persons with psychotic disorders in the Finnish SUPER study. Eur Psychiatry. 2025;68 (1):e99. doi: 10.1192/j.eurpsy.2025.10066. PubMed PMID:40670906 PubMed Central PMC12344466.
  7. Mökkönen, T, Solismaa, A, Hämäläinen, M, Moilanen, E, Kampman, O. IL-8 and IL-1RA serum levels predicting depression treatment response in 6-week follow-up. Acta Neuropsychiatr. 2025;37 :e83. doi: 10.1017/neu.2025.10027. PubMed PMID:40619839 .
  8. Malkki, VK, Saarni, SE, Lutz, W, Rosenström, TH. Targeted Learning for Optimal Patient Assignment to Psychotherapy. Psychother Res. 2025; :1-15. doi: 10.1080/10503307.2025.2517567. PubMed PMID:40544478 .
  9. McGilvrey, MI, Fortier, B, Cooke, D, Mahdi, MA, Tero, B, Potts, CM et al.. Short-term dietary methionine restriction with high fat diet counteracts metabolic dysfunction in male mice. Physiol Rep. 2025;13 (12):e70405. doi: 10.14814/phy2.70405. PubMed PMID:40526038 PubMed Central PMC12172570.
  10. Leppänen, H, Kampman, O, Autio, R, Tanskanen, A, Taipale, H, Karolaakso, T et al.. Socioeconomic status, antidepressant use, and return to work after disability due to common mental disorders. Eur Psychiatry. 2025;68 (1):e79. doi: 10.1192/j.eurpsy.2025.10046. PubMed PMID:40509735 PubMed Central PMC12188336.
  11. Mustonen, A, Taipale, H, Denissoff, A, Ellilä, V, Di Forti, M, Tanskanen, A et al.. Real-world effectiveness of antipsychotic medication in relapse prevention after cannabis-induced psychosis. Br J Psychiatry. 2025; :1-7. doi: 10.1192/bjp.2025.72. PubMed PMID:40326094 .
  12. Konola, VM, Multanen, J, Ihalainen, JK, Hintikka, JE, Jämsä, T, Kautiainen, H et al.. Effects of high impact exercise on systemic cytokines in women with mild knee osteoarthritis: A 12-month RCT. Osteoarthr Cartil Open. 2025;7 (2):100609. doi: 10.1016/j.ocarto.2025.100609. PubMed PMID:40290652 PubMed Central PMC12033985.
  13. Cederlöf, E, Holm, M, Kämpe, A, Ahola-Olli, A, Kantojärvi, K, Lähteenvuo, M et al.. Sleep and schizophrenia polygenic scores in non-affective and affective psychotic disorders. Psychol Med. 2025;55 :e117. doi: 10.1017/S0033291725000844. PubMed PMID:40230302 PubMed Central PMC12094621.
  14. Schwartz, B, Gonçalves, MM, Lutz, W, Oliveira, JT, Saarni, SE, Tishby, O et al.. Response to the Commentary “Can a 1-Item Scale for Psychotherapy Outcomes Be Psychometrically Robust?”. Clin Psychol Eur. 2025;7 (1):e16921. doi: 10.32872/cpe.16921. PubMed PMID:40177336 PubMed Central PMC11960558.
  15. Hietala, E, Solismaa, A, Lähteenvuo, M, Ahola-Olli, AV, Häkkinen, K, Suokas, K et al.. Influence of CYP2D6 phenotype on adherence, adverse effects, and attitudes in aripiprazole and risperidone users. Acta Neuropsychiatr. 2025;37 :e54. doi: 10.1017/neu.2025.11. PubMed PMID:40130908 .
  16. Mylläri, S, Saarni, SE, Joffe, G, Ritola, V, Stenberg, JH, Rosenström, TH et al.. Machine learned text topics improve drop-out risk prediction but not symptom prediction in online psychotherapies for depression and anxiety. Psychother Res. 2026;36 (2):387-402. doi: 10.1080/10503307.2025.2473921. PubMed PMID:40101214 .
  17. Driuchina, A, Isola, V, Hulmi, JJ, Salmi, VM, Hintikka, J, Ahtiainen, JP et al.. Unveiling the impact of competition weight loss on gut microbiota: alterations in diversity, composition, and predicted metabolic functions. J Int Soc Sports Nutr. 2025;22 (1):2474561. doi: 10.1080/15502783.2025.2474561. PubMed PMID:40033182 PubMed Central PMC11881659.
  18. Höyhtyä, M, Haaramo, A, Nikkonen, A, Ventin-Holmberg, R, Agrawal, N, Ritari, J et al.. Fecal microbiota and genetics in pediatric-onset orofacial granulomatosis and Crohn´s disease. Sci Rep. 2025;15 (1):6020. doi: 10.1038/s41598-025-90243-5. PubMed PMID:39972069 PubMed Central PMC11839994.
  19. Rosenström, TH, Saarni, SE, Saarni, SI, Tammilehto, J, Stenberg, JH. Efficacy and effectiveness of therapist-guided internet versus face-to-face cognitive behavioural therapy for depression via counterfactual inference using naturalistic registers and machine learning in Finland: a retrospective cohort study. Lancet Psychiatry. 2025;12 (3):189-197. doi: 10.1016/S2215-0366(24)00404-8. PubMed PMID:39954684 .
  20. van Rheenen, PF, Kolho, KL, Russell, RK, Aloi, M, Deganello, A, Hussey, S et al.. Primary sclerosing cholangitis in children with inflammatory bowel disease: An ESPGHAN position paper from the Hepatology Committee and the IBD Porto group. J Pediatr Gastroenterol Nutr. 2025;80 (2):374-393. doi: 10.1002/jpn3.12378. PubMed PMID:39741383 PubMed Central PMC11788976.
  21. Lähteenvuo, M, Tiihonen, J, Solismaa, A, Tanskanen, A, Mittendorfer-Rutz, E, Taipale, H et al.. Repurposing Semaglutide and Liraglutide for Alcohol Use Disorder. JAMA Psychiatry. 2025;82 (1):94-98. doi: 10.1001/jamapsychiatry.2024.3599. PubMed PMID:39535805 PubMed Central PMC11561716.
  22. Puranen, T, Hiltunen, K, Pitkälä, KH, Roitto, HM, Mäntylä, P, Saarela, RKT et al.. Association of oral frailty with falls in long-term care residents. Eur Geriatr Med. 2025;16 (1):191-195. doi: 10.1007/s41999-024-01088-6. PubMed PMID:39500813 PubMed Central PMC11850447.
  23. DeMaria, WG, Figueroa-Milla, AE, Kaija, A, Harrington, AE, Tero, B, Ryzhova, L et al.. Endothelial Cells Increase Mesenchymal Stem Cell Differentiation in Scaffold-Free 3D Vascular Tissue. Tissue Eng Part A. 2025;31 (11-12):456-470. doi: 10.1089/ten.TEA.2024.0122. PubMed PMID:39109944 PubMed Central PMC12184959.

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2024

  1. van Rheenen, PF, Kolho, KL, Russell, RK, Aloi, M, Deganello, A, Hussey, S et al.. Primary sclerosing cholangitis in children with inflammatory bowel disease: An ESPGHAN position paper from the Hepatology Committee and the IBD Porto group. J Pediatr Gastroenterol Nutr. 2025;80 (2):374-393. doi: 10.1002/jpn3.12378. PubMed PMID:39741383 PubMed Central PMC11788976.
  2. Ahti, J, Kieseppä, T, Haaki, W, Suvisaari, J, Niemelä, S, Suokas, K et al.. General medical comorbidities in psychotic disorders in the Finnish SUPER study. Schizophrenia (Heidelb). 2024;10 (1):124. doi: 10.1038/s41537-024-00546-1. PubMed PMID:39741144 PubMed Central PMC11688420.
  3. Gonçalves, MM, Lutz, W, Schwartz, B, Oliveira, JT, Saarni, SE, Tishby, O et al.. Developing a European Psychotherapy Consortium (EPoC): Towards Adopting a Single-Item Self-Report Outcome Measure Across European Countries. Clin Psychol Eur. 2024;6 (3):e13827. doi: 10.32872/cpe.13827. PubMed PMID:39678318 PubMed Central PMC11636744.
  4. Tavast, IM, Solismaa, A, Lyytikäinen, LP, Mononen, N, Moilanen, E, Hämäläinen, M et al.. Leptin and leptin receptor gene polymorphisms and depression treatment response. Acta Neuropsychiatr. 2024;37 :e38. doi: 10.1017/neu.2024.43. PubMed PMID:39529327 .
  5. Porvari, K, Horioka, K, Kaija, H, Pakanen, L. is overexpressed in human cardiac tissue in hypothermia deaths; associations between the transcript and stress hormone levels in cardiac deaths. Ann Med. 2024;56 (1):2420862. doi: 10.1080/07853890.2024.2420862. PubMed PMID:39506618 PubMed Central PMC11544741.
  6. Puranen, T, Hiltunen, K, Pitkälä, KH, Roitto, HM, Mäntylä, P, Saarela, RKT et al.. Association of oral frailty with falls in long-term care residents. Eur Geriatr Med. 2025;16 (1):191-195. doi: 10.1007/s41999-024-01088-6. PubMed PMID:39500813 PubMed Central PMC11850447.
  7. Partanen, JJ, Häppölä, P, Kämpe, A, Ahola-Olli, A, Hellsten, A, Rask, SM et al.. High Burden of Ileus and Pneumonia in Clozapine-Treated Individuals With Schizophrenia: A Finnish 25-Year Follow-Up Register Study. Am J Psychiatry. 2024;181 (10):879-892. doi: 10.1176/appi.ajp.20230744. PubMed PMID:39262212 .
  8. DeMaria, WG, Figueroa-Milla, AE, Kaija, A, Harrington, AE, Tero, B, Ryzhova, L et al.. Endothelial Cells Increase Mesenchymal Stem Cell Differentiation in Scaffold-Free 3D Vascular Tissue. Tissue Eng Part A. 2025;31 (11-12):456-470. doi: 10.1089/ten.TEA.2024.0122. PubMed PMID:39109944 PubMed Central PMC12184959.
  9. Mikkonen, K, Helminen, EE, Saarni, SI, Saarni, SE. Learning Outcomes of e-Learning in Psychotherapy Training and Comparison With Conventional Training Methods: Systematic Review. J Med Internet Res. 2024;26 :e54473. doi: 10.2196/54473. PubMed PMID:39073862 PubMed Central PMC11319893.
  10. Savander, EÉ, Voutilainen, L, Hintikka, J, Peräkylä, A. What to take up from the patient’s talk? The clinician’s responses to the patient’s self-disclosure of their subjective experience in the psychiatric intake interview. Front Psychiatry. 2024;15 :1352601. doi: 10.3389/fpsyt.2024.1352601. PubMed PMID:38974916 PubMed Central PMC11224953.
  11. Solasaari, T, Korpela, K, Lommi, S, Hyvönen, S, Gardemeister, S, Merras-Salmio, L et al.. Bowel function in a prospective cohort of 1052 healthy term infants up to 4 months of age. Eur J Pediatr. 2024;183 (8):3557-3565. doi: 10.1007/s00431-024-05625-0. PubMed PMID:38819500 PubMed Central PMC11263225.
  12. Freborg, K. Where Is the Humanity for Nurses? A Love Letter to My Fellow Nurse. J Emerg Nurs. 2024;50 (3):322-323. doi: 10.1016/j.jen.2024.02.003. PubMed PMID:38705703 .
  13. Kolho, KL, Nikkonen, A, Merras-Salmio, L, Molander, P. The need for surgery in pediatric patients with inflammatory bowel disease treated with biologicals. Int J Colorectal Dis. 2024;39 (1):58. doi: 10.1007/s00384-024-04634-7. PubMed PMID:38661931 PubMed Central PMC11045629.
  14. Soucy, A, Potts, C, Kaija, A, Harrington, A, McGilvrey, M, Sutphin, GL et al.. Effects of a Global Null Mutation on Murine PVAT and Cardiovascular Function. Arterioscler Thromb Vasc Biol. 2024;44 (7):1601-1616. doi: 10.1161/ATVBAHA.124.320969. PubMed PMID:38660803 PubMed Central PMC11209784.
  15. Sandström, K, Kampman, O, Asellus, P. A retrospective analysis of iv ketamine outcome on hospitalisations in an unselected psychiatric sample. Acta Neuropsychiatr. 2024;37 :e13. doi: 10.1017/neu.2024.18. PubMed PMID:38659205 .
  16. Puolakka, H, Solismaa, A, Lyytikäinen, LP, Viikki, M, Seppälä, N, Mononen, N et al.. Polymorphisms in and associated with dry mouth in clozapine-treated patients. Acta Neuropsychiatr. 2024;36 (4):218-223. doi: 10.1017/neu.2024.9. PubMed PMID:38634369 .
  17. Cederlöf, E, Holm, M, Taipale, H, Tiihonen, J, Tanskanen, A, Lähteenvuo, M et al.. Antipsychotic medications and sleep problems in patients with schizophrenia. Schizophr Res. 2024;267 :230-238. doi: 10.1016/j.schres.2024.03.015. PubMed PMID:38579432 .
  18. Kämpe, A, Suvisaari, J, Lähteenvuo, M, Singh, T, Ahola-Olli, A, Urpa, L et al.. Genetic contribution to disease-course severity and progression in the SUPER-Finland study, a cohort of 10,403 individuals with psychotic disorders. Mol Psychiatry. 2024;29 (9):2733-2741. doi: 10.1038/s41380-024-02516-6. PubMed PMID:38556557 PubMed Central PMC11420086.
  19. Denissoff, A, Taipale, H, Tiihonen, J, Di Forti, M, Mittendorfer-Rutz, E, Tanskanen, A et al.. Antipsychotic Use and Psychiatric Hospitalization in First-Episode Non-affective Psychosis and Cannabis Use Disorder: A Swedish Nationwide Cohort Study. Schizophr Bull. 2024;50 (6):1287-1294. doi: 10.1093/schbul/sbae034. PubMed PMID:38534050 PubMed Central PMC11578669.
  20. Mäkipelto, V, Tuulio-Henriksson, A, Hakulinen, C, Niemelä, S, Lähteenvuo, M, Wegelius, A et al.. Association of antidepressant and benzodiazepine use, and anticholinergic burden with cognitive performance in schizophrenia. Schizophr Res. 2024;266 :118-126. doi: 10.1016/j.schres.2024.02.025. PubMed PMID:38401410 .
  21. Levola, J, Alakokkare, AE, Denissoff, A, Mustonen, A, Miettunen, J, Niemelä, S et al.. Adolescent alcohol and cannabis use and early adulthood educational attainment in the 1986 Northern Finland birth cohort study. BMC Public Health. 2024;24 (1):255. doi: 10.1186/s12889-024-17693-w. PubMed PMID:38254063 PubMed Central PMC10804574.
  22. Julkunen, L, Saarela, R, Roitto, HM, Kautiainen, H, Pitkälä, K, Mäntylä, P et al.. Oral frailty among dentate and edentate older adults in long-term care. BMC Geriatr. 2024;24 (1):48. doi: 10.1186/s12877-023-04605-7. PubMed PMID:38212720 PubMed Central PMC10782602.
  23. Hemming-Harlo, M, Merras-Salmio, L, Nikkonen, A, Kolho, KL. Drug levels of VEDOLIZUMAB in patients with pediatric-onset inflammatory bowel disease in a real-life setting. Eur J Pediatr. 2024;183 (1):313-322. doi: 10.1007/s00431-023-05255-y. PubMed PMID:37878072 PubMed Central PMC10858127.
  24. Salminen, SP, Solismaa, A, Lyytikäinen, LP, Paavonen, V, Mononen, N, Lehtimäki, T et al.. Genetic risk scores associated with temperament clusters in Finnish depression patients. Acta Neuropsychiatr. 2024;36 (1):51-59. doi: 10.1017/neu.2023.33. PubMed PMID:37665031 .
  25. Leppänen, H, Kampman, O, Autio, R, Karolaakso, T, Rissanen, P, Näppilä, T et al.. Socioeconomic status, psychotherapy duration, and return to work from disability due to common mental disorders. Psychother Res. 2024;34 (5):694-707. doi: 10.1080/10503307.2023.2229500. PubMed PMID:37399567 .
  26. Suokas, K, Kurkela, O, Nevalainen, J, Suvisaari, J, Hakulinen, C, Kampman, O et al.. Geographical variation in treated psychotic and other mental disorders in Finland by region and urbanicity. Soc Psychiatry Psychiatr Epidemiol. 2024;59 (1):37-49. doi: 10.1007/s00127-023-02516-x. PubMed PMID:37308692 PubMed Central PMC10799825.

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