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Radiotherapy and oncology

Publications

2024

  1. Parviainen, E, Nurmenniemi, S, Ravaioli, S, Bravaccini, S, Manninen, A, Jukkola, A et al.. Human papillomavirus E6 alters Toll-like receptor 9 transcripts and chemotherapy responses in breast cancer cells in vitro. Mol Biol Rep. 2024;52 (1):43. doi: 10.1007/s11033-024-10143-1. PubMed PMID:39644451 PubMed Central PMC11625066.
  2. Tastula, A, Jukkola, A, Alakokkare, AE, Nordström, T, Karihtala, P, Miettunen, J et al.. Depression and Anxiety Symptoms Before and After Breast-Cancer Diagnosis Among Young Women in the Northern Finland Birth Cohort 1966. Eur J Breast Health. 2024;20 (4):292-302. doi: 10.4274/ejbh.galenos.2024.2024-7-1. PubMed PMID:39323325 PubMed Central PMC11589186.
  3. Tuunanen, I, Hautakoski, A, Huhtamäki, H, Arffman, M, Sund, R, Puistola, U et al.. The Association of Metformin, Other Antidiabetic Medications, and Statins with the Prognosis of Hepatocellular Carcinoma in Patients with Type 2 Diabetes: A Retrospective Cohort Study. Biomedicines. 2024;12 (8):. doi: 10.3390/biomedicines12081654. PubMed PMID:39200117 PubMed Central PMC11351525.
  4. Hosio, M, Urpilainen, E, Hautakoski, A, Arffman, M, Sund, R, Ahtikoski, A et al.. The association of breast cancer patients survival and prior menopausal hormone therapy in women with type 2 diabetes. Sci Rep. 2024;14 (1):16478. doi: 10.1038/s41598-024-65916-2. PubMed PMID:39013999 PubMed Central PMC11252321.
  5. Harmanen, M, Sorigue, M, Khan, M, Prusila, R, Klaavuniemi, T, Kari, E et al.. Front-line and second-line treatment for mantle cell lymphoma in clinical practice: A multicenter retrospective analysis. Eur J Haematol. 2024;113 (2):218-226. doi: 10.1111/ejh.14219. PubMed PMID:38661269 .
  6. Karihtala, P, Leivonen, SK, Puistola, U, Urpilainen, E, Jääskeläinen, A, Leppä, S et al.. Serum protein profiling reveals an inflammation signature as a predictor of early breast cancer survival. Breast Cancer Res. 2024;26 (1):61. doi: 10.1186/s13058-024-01812-x. PubMed PMID:38594742 PubMed Central PMC11005292.
  7. Mäenpää, N, Tiainen, L, Hämäläinen, M, Luukkaala, T, Tanner, M, Lahdenperä, O et al.. Neuropilin-1 and placental growth factor as prognostic factors in metastatic breast cancer. BMC Cancer. 2024;24 (1):331. doi: 10.1186/s12885-024-12070-7. PubMed PMID:38468231 PubMed Central PMC10929217.
  8. Mishra, S, Tejesvi, MV, Hekkala, J, Turunen, J, Kandikanti, N, Kaisanlahti, A et al.. Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours. J Adv Res. 2024; :. doi: 10.1016/j.jare.2024.03.003. PubMed PMID:38458256 .

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2023
  1. Murto, MO, Simolin, N, Arponen, O, Siltari, A, Artama, M, Visvanathan, K et al.. Statin Use, Cholesterol Level, and Mortality Among Females With Breast Cancer. JAMA Netw Open. 2023;6 (11):e2343861. doi: 10.1001/jamanetworkopen.2023.43861. PubMed PMID:37976058 PubMed Central PMC10656638.
  2. Rautajoki, KJ, Jaatinen, S, Hartewig, A, Tiihonen, AM, Annala, M, Salonen, I et al.. Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting. Acta Neuropathol Commun. 2023;11 (1):176. doi: 10.1186/s40478-023-01669-9. PubMed PMID:37932833 PubMed Central PMC10629206.
  3. Harmanen, M, Klaavuniemi, T, Sorigue, M, Khan, M, Prusila, R, Kari, E et al.. Real-world Data: MCL2 Protocol Demonstrates Excellent Treatment Results Among Patients With Mantle Cell Lymphoma Not Fulfilling the Original Trial Inclusion Criteria. Hemasphere. 2023;7 (10):e954. doi: 10.1097/HS9.0000000000000954. PubMed PMID:37693119 PubMed Central PMC10489256.
  4. Sassi, A, Salminen, A, Jukkola, A, Tervo, M, Mäenpää, N, Turtiainen, S et al.. Breast density and the likelihood of malignant MRI-detected lesions in women diagnosed with breast cancer. Eur Radiol. 2023;33 (11):8080-8088. doi: 10.1007/s00330-023-10072-w. PubMed PMID:37646814 PubMed Central PMC10598189.
  5. Petruk, N, Siddiqui, A, Tadayon, S, Määttä, J, Mattila, PK, Jukkola, A et al.. CD73 regulates zoledronate-induced lymphocyte infiltration in triple-negative breast cancer tumors and lung metastases. Front Immunol. 2023;14 :1179022. doi: 10.3389/fimmu.2023.1179022. PubMed PMID:37533856 PubMed Central PMC10390692.
  6. Jokimäki, A, Hietala, H, Lemma, J, Karhapää, H, Rintala, A, Kaikkonen, JP et al.. Previous radiotherapy improves treatment responses and causes a trend toward longer time to progression among patients with immune checkpoint inhibitor-related adverse events. Cancer Immunol Immunother. 2023;72 (10):3337-3347. doi: 10.1007/s00262-023-03494-4. PubMed PMID:37486396 PubMed Central PMC10491510.
  7. Natukka, T, Haapasalo, J, Kivioja, T, Rajala, L, Raitanen, J, Nevalainen, J et al.. Impact of Timing of Surgery and Adjuvant Treatment on Survival of Adult IDH-wild-type Glioblastoma: A Single-center Study of 392 Patients. World Neurosurg. 2023; :. doi: 10.1016/j.wneu.2023.07.008. PubMed PMID:37423335 .
  8. Ahvonen, J, Luukkaala, T, Laitinen, T, Jukkola, A. Survival with lung cancer in Finland has not improved during 2007-2019-a single center retrospective population-based real-world study. Acta Oncol. 2023;62 (6):571-578. doi: 10.1080/0284186X.2023.2213444. PubMed PMID:37257498 .
  9. Harmanen, M, Hujo, M, Sund, R, Sorigue, M, Khan, M, Prusila, R et al.. Survival of patients with mantle cell lymphoma in the rituximab era: Retrospective binational analysis between 2000 and 2020. Br J Haematol. 2023;201 (1):64-74. doi: 10.1111/bjh.18597. PubMed PMID:36513500 .

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2022
  1. Harmanen, M, Hujo, M, Sund, R, Sorigue, M, Khan, M, Prusila, R et al.. Survival of patients with mantle cell lymphoma in the rituximab era: Retrospective binational analysis between 2000 and 2020. Br J Haematol. 2023;201 (1):64-74. doi: 10.1111/bjh.18597. PubMed PMID:36513500 .
  2. Erkinantti, S, Hautakoski, A, Sund, R, Arffman, M, Urpilainen, E, Puistola, U et al.. The Association of Metformin, Other Antidiabetic Medications, and Statins With the Prognosis of Colon Cancer in Patients With Type 2 Diabetes: A Retrospective Cohort Study. Cancer Control. 2022;29 :10732748221134090. doi: 10.1177/10732748221134090. PubMed PMID:36422298 PubMed Central PMC9703554.
  3. Erkinantti, S, Hautakoski, A, Sund, R, Arffman, M, Urpilainen, E, Puistola, U et al.. The Association of Metformin, Other Antidiabetic Medications and Statins on the Prognosis of Rectal Cancer in Patients with Type 2 Diabetes: A Retrospective Cohort Study. Biomolecules. 2022;12 (9):. doi: 10.3390/biom12091301. PubMed PMID:36139140 PubMed Central PMC9496504.
  4. Joensuu, H, Kellokumpu-Lehtinen, PL, Huovinen, R, Jukkola, A, Tanner, M, Ahlgren, J et al.. Adjuvant Capecitabine for Early Breast Cancer: 15-Year Overall Survival Results From a Randomized Trial. J Clin Oncol. 2022;40 (10):1051-1058. doi: 10.1200/JCO.21.02054. PubMed PMID:35020465 PubMed Central PMC8966968.
  5. Myller, S, Jukkola, A, Jääskeläinen, A, Roininen, N, Karihtala, P. How breast cancer recurrences are found – a real-world, prospective cohort study. Acta Oncol. 2022;61 (4):417-424. doi: 10.1080/0284186X.2021.2023756. PubMed PMID:34986730 .
  6. Ventelä, J, Nikkilä, A, Jukkola, A, Lohi, O. Incidence and outcomes of cancer in 16- to 17-year-old adolescents. Acta Paediatr. 2022;111 (2):442-444. doi: 10.1111/apa.16161. PubMed PMID:34689375 PubMed Central PMC9299452.

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2021
  1. Ventelä, J, Nikkilä, A, Jukkola, A, Lohi, O. Incidence and outcomes of cancer in 16- to 17-year-old adolescents. Acta Paediatr. 2022;111 (2):442-444. doi: 10.1111/apa.16161. PubMed PMID:34689375 .
  2. Moisander, M, Salminen, A, Jukkola, A, Sassi, A, Tervo, M, Mäenpää, N et al.. Radiological and pathological assessment of response to neoadjuvant CDK4/6 inhibitor and endocrine treatments in a real-life setting-initial results. Acta Radiol Open. 2021;10 (8):20584601211030660. doi: 10.1177/20584601211030660. PubMed PMID:34422318 PubMed Central PMC8377317.
  3. Hosio, M, Urpilainen, E, Hautakoski, A, Marttila, M, Arffman, M, Sund, R et al.. Association of antidiabetic medication and statins with survival from ductal and lobular breast carcinoma in women with type 2 diabetes. Sci Rep. 2021;11 (1):10445. doi: 10.1038/s41598-021-88488-x. PubMed PMID:34001921 PubMed Central PMC8129135.
  4. Petruk, N, Tuominen, S, Åkerfelt, M, Mattsson, J, Sandholm, J, Nees, M et al.. CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer. Sci Rep. 2021;11 (1):6035. doi: 10.1038/s41598-021-85379-z. PubMed PMID:33727591 PubMed Central PMC7966763.
  5. Tastula, A, Jukkola, A, Alakokkare, AE, Nordström, T, Eteläinen, S, Karihtala, P et al.. Early-Life Risk Factors for Breast Cancer – Prospective Follow-up in the Northern Finland Birth Cohort 1966. Cancer Epidemiol Biomarkers Prev. 2021;30 (4):616-622. doi: 10.1158/1055-9965.EPI-20-1442. PubMed PMID:33563646 .
  6. Karihtala, P, Jääskeläinen, A, Roininen, N, Jukkola, A. Real-world, single-centre prospective data of age at breast cancer onset: focus on survival and reproductive history. BMJ Open. 2021;11 (1):e041706. doi: 10.1136/bmjopen-2020-041706. PubMed PMID:33518519 PubMed Central PMC7852949.
  7. Erkinantti, S, Marttila, M, Sund, R, Arffman, M, Urpilainen, E, Puistola, U et al.. Association of Metformin, Other Antidiabetic Medications, and Statins With Incidence of Colon Cancer in Patients With Type 2 Diabetes. Clin Colorectal Cancer. 2021;20 (2):e113-e119. doi: 10.1016/j.clcc.2020.11.003. PubMed PMID:33279415 .

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2020
  1. Erkinantti, S, Marttila, M, Sund, R, Arffman, M, Urpilainen, E, Puistola, U et al.. Association of Metformin, Other Antidiabetic Medications, and Statins With Incidence of Colon Cancer in Patients With Type 2 Diabetes. Clin Colorectal Cancer. 2021;20 (2):e113-e119. doi: 10.1016/j.clcc.2020.11.003. PubMed PMID:33279415 .
  2. Karihtala, P, Jääskeläinen, A, Roininen, N, Jukkola, A. Prognostic factors in metastatic breast cancer: a prospective single-centre cohort study in a Finnish University Hospital. BMJ Open. 2020;10 (10):e038798. doi: 10.1136/bmjopen-2020-038798. PubMed PMID:33046470 PubMed Central PMC7552835.
  3. Jääskeläinen, A, Roininen, N, Karihtala, P, Jukkola, A. High Parity Predicts Poor Outcomes in Patients With Luminal B-Like (HER2 Negative) Early Breast Cancer: A Prospective Finnish Single-Center Study. Front Oncol. 2020;10 :1470. doi: 10.3389/fonc.2020.01470. PubMed PMID:32923400 PubMed Central PMC7457016.
  4. Hosio, M, Urpilainen, E, Hautakoski, A, Marttila, M, Arffman, M, Sund, R et al.. Survival after breast cancer in women with type 2 diabetes using antidiabetic medication and statins: a retrospective cohort study. Acta Oncol. 2020;59 (9):1110-1117. doi: 10.1080/0284186X.2020.1769858. PubMed PMID:32478629 .
  5. Myller, S, Ipatti, P, Jääskeläinen, A, Haapasaari, KM, Jukkola, A, Karihtala, P et al.. Early progression of breast cancer during neoadjuvant chemotherapy may predict poorer prognoses. Acta Oncol. 2020;59 (9):1036-1042. doi: 10.1080/0284186X.2020.1760350. PubMed PMID:32394761 .

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2019
  1. Jääskeläinen, A, Jukkola, A, Haapasaari, KM, Auvinen, P, Soini, Y, Karihtala, P et al.. Cytoplasmic Mineralocorticoid Receptor Expression Predicts Dismal Local Relapse-free Survival in Non-triple-negative Breast Cancer. Anticancer Res. 2019;39 (11):5879-5890. doi: 10.21873/anticanres.13792. PubMed PMID:31704812 .
  2. Tiainen, L, Korhonen, EA, Leppänen, VM, Luukkaala, T, Hämäläinen, M, Tanner, M et al.. High baseline Tie1 level predicts poor survival in metastatic breast cancer. BMC Cancer. 2019;19 (1):732. doi: 10.1186/s12885-019-5959-8. PubMed PMID:31340773 PubMed Central PMC6657075.
  3. Jääskeläinen, A, Jukkola, A, Risteli, J, Haapasaari, KM, Karihtala, P. Elevated preoperative serum levels of collagen I carboxyterminal telopeptide predict better outcome in early-stage luminal-B-like (HER2-negative) and triple-negative subtypes of breast cancer. Tumour Biol. 2019;41 (5):1010428319847081. doi: 10.1177/1010428319847081. PubMed PMID:31122159 .
  4. Tiainen, L, Hämäläinen, M, Luukkaala, T, Tanner, M, Lahdenperä, O, Vihinen, P et al.. Low Plasma IL-8 Levels During Chemotherapy Are Predictive of Excellent Long-Term Survival in Metastatic Breast Cancer. Clin Breast Cancer. 2019;19 (4):e522-e533. doi: 10.1016/j.clbc.2019.03.006. PubMed PMID:31029558 .
  5. Hosio, M, Urpilainen, E, Marttila, M, Hautakoski, A, Arffman, M, Sund, R et al.. Association of antidiabetic medication and statins with breast cancer incidence in women with type 2 diabetes. Breast Cancer Res Treat. 2019;175 (3):741-748. doi: 10.1007/s10549-019-05185-0. PubMed PMID:30895533 PubMed Central PMC6534663.

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