Current projects
LiverTarget
LiverTarget is an EU-funded Research and Innovation Action project designed to develop a new generation of advanced RNA therapeutics that will reduce disease burden e.g. myocardial infarct and will improve their quality of life in the future, if the lead compound(s) successfully pass the phase 1-3 clinical trials after this project. LiverTarget will significantly boost European innovation capacity in the field of personalized nanomedicines using unique RNA technology. We expect that this innovative approach will later lead to beneficial health economic implications as it may lower the costs per quality- adjusted life year.
Project web page: LiverTarget
SMASH-HCM PROJECT
SMASH-HCM, an initiative focused on transforming the landscape of Hypertrophic Cardiomyopathy (HCM). Our project aims to develop a cutting-edge digital-twin platform, integrating dynamic biophysical models and data-driven insights for personalized HCM stratification and improved disease management. Join us in advancing the state of the art in human digital-twins, delivering new insights, enhanced patient care, and a validated strategy through a pilot clinical trial.
Project web page: SMASH-HCM PROJECT
CVDLINK
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, responsible for 17.9 million fatalities per year, according to the WHO. In Europe, this number is growing, incurring staggering costs to human life, healthcare systems, and society more broadly.
CVDLINK approaches this problem by applying innovative solutions to an everyday tool: data.
First, we’ll integrate multimodal data sets from hospitals, researchers, and health authorities across Europe and Israel, translating them into a uniform format while paying close attention to the ethical and legal principles regulating the management of sensitive health data.
Next, we’ll develop AI models which will analyse this unified dataset and produce tools to aid in the prevention, diagnosis, and risk stratification of CVDs. These will be available via CVDLINK’s Platform as a Service (PaaS), which will offer custom visualisations to healthcare practitioners and researchers in the cardiovascular domain. Finally, we’ll perform studies in five countries to validate our outputs and ensure they meet the needs of our end users.
CVDLINK pairs routine health data with cutting-edge technology to provide effective, evidence-driven interventions with the potential to transform public health. Along the way, the project’s interdisciplinary team, which includes ethicists, clinicians, tech developers, and communication experts, aims to build trust in AI and data-powered medical tools.
Project web page: CVDLINK
ThrombUS+
The ThrombUS+ project is focused on developing a novel wearable diagnostic device to aid in the early detection and diagnosis of deep vein thrombosis (DVT). The project integrates cutting-edge technologies, including ultrasound, artificial intelligence, light reflection rheography, plethysmography, serious games, and extended reality, to create a comprehensive and user-friendly monitoring system. ThrombUS+ aims to provide patients and healthcare professionals with real-time insights, enhancing DVT diagnosis and treatment.
Project web page: ThrombUS+
CoroPrevention
CoroPrevention project aims to discover long-term behaviour changes and lifestyle improvements as well as medications needed by individual patients with coronary heart disease to prevent another cardiovascular event.
Project web page: CoroPrevention
Past projects
TAXINOMISIS project
A multidisciplinary approach for the stratification of patients with carotid artery disease.
Project web page: Taxinomisis Project
TO_AITION
The project will effectuate basic, preclinical and clinical research applying data-driven strategies to detect and describe immune-metabolic mechanisms responsible for CVD-depression comorbidity, aiming to improve diagnosis and management of the disease.
Project web page: TO_AITION
RISKYCAD
Final Report Summary – RISKYCAD (Personalized diagnostics and treatment of high risk coronary artery disease patients.) Periodic Report Summary 1 – RISKYCAD (Personalized diagnostics and treatment of high risk coronary artery disease patients.)
Project web page: RISKYCAD
ARTHEROFLUX
Targeting novel lipid pathways for treatment of cardiovascular disease.
Project web page: ARTHEROFLUX
ATHEROREMO Consortium
The health of the EC population has never been better. However, serious public health problems remain, which cannot be ignored including high levels of premature deaths due to cardiovascular diseases.
Project web page: ATHEROREMO