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Obstetrics and Clinical Genetics

Publications

2024

  1. Salo, V, Määttä, J, Sliz, E, FinnGen, Reimann, E, Mägi, R et al.. Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations. Nat Commun. 2024;15 (1):9424. doi: 10.1038/s41467-024-53467-z. PubMed PMID:39511132 PubMed Central PMC11544010.
  2. Eteläinen, S, Keikkala, E, Lingaiah, S, Viljakainen, M, Männistö, T, Pouta, A et al.. Perinatal and neonatal outcomes in gestational diabetes: The importance of the number of abnormal values in an oral glucose tolerance test. Acta Obstet Gynecol Scand. 2024; :. doi: 10.1111/aogs.14999. PubMed PMID:39473341 .
  3. Lahti-Pulkkinen, M, Lähdepuro, A, Lahti, J, Girchenko, P, Pyhälä, R, Reynolds, RM et al.. Maternal psychological distress and temperament traits in children from infancy to late childhood. JCPP Adv. 2024;4 (3):e12242. doi: 10.1002/jcv2.12242. PubMed PMID:39411467 PubMed Central PMC11472812.
  4. Pasanen, A, Karjalainen, MK, Korppi, M, Hallman, M, Rämet, M, Research Project FinnGen
    et al.. Genetic susceptibility to acute viral bronchiolitis. J Infect Dis. 2024; :. doi: 10.1093/infdis/jiae467. PubMed PMID:39299705 .
  5. Allotey, J, Archer, L, Snell, KIE, Coomar, D, Massé, J, Sletner, L et al.. Development and validation of a prognostic model to predict birth weight: individual participant data meta-analysis. BMJ Med. 2024;3 (1):e000784. doi: 10.1136/bmjmed-2023-000784. PubMed PMID:39184566 PubMed Central PMC11344865.
  6. Hanevik, HI, Bergh, C, Laivuori, H, Spangmose, AL, Magnusson, Å, Pinborg, A et al.. Limiting access to assisted reproductive technologies for males of advanced age-Pros and cons from a Nordic perspective. Acta Obstet Gynecol Scand. 2024;103 (11):2124-2129. doi: 10.1111/aogs.14944. PubMed PMID:39140140 PubMed Central PMC11502453.
  7. Girchenko, P, Lahti-Pulkkinen, M, Laivuori, H, Kajantie, E, Räikkönen, K. Maternal Antenatal Depression Is Associated With Metabolic Alterations That Predict Birth Outcomes and Child Neurodevelopment and Mental Health. Biol Psychiatry. 2024; :. doi: 10.1016/j.biopsych.2024.07.023. PubMed PMID:39127233 .
  8. Westergaard, D, Steinthorsdottir, V, Stefansdottir, L, Rohde, PD, Wu, X, Geller, F et al.. Genome-wide association meta-analysis identifies five loci associated with postpartum hemorrhage. Nat Genet. 2024;56 (8):1597-1603. doi: 10.1038/s41588-024-01839-y. PubMed PMID:39039282 PubMed Central PMC11319197.
  9. Renlund-Vikström, M, Jääskeläinen, TJ, Kivelä, A, Heinonen, S, Laivuori, H, Sarkola, T et al.. Cardiac Structure and Function in 8- to 12-Year-Old Children Following In-Utero Exposure to Preeclampsia (FINNCARE Study). J Am Heart Assoc. 2024;13 (15):e034494. doi: 10.1161/JAHA.124.034494. PubMed PMID:39011963 .
  10. Pohjola, A, Vest, T, Verho, L, Aarnio, K, Rantanen, K, Laivuori, H et al.. Intracranial Arteriovenous Malformations During Pregnancy and Puerperium-A Retrospective Nationwide Population-Based Cohort Study. Neurosurgery. 2024; :. doi: 10.1227/neu.0000000000003067. PubMed PMID:38934658 .
  11. Häkkinen, I, Yazgeldi Gunaydin, G, Pyöriä, L, Kojima, S, Parrish, N, Perdomo, MF et al.. Fetal cord plasma herpesviruses and preeclampsia: an observational cohort study. Sci Rep. 2024;14 (1):14605. doi: 10.1038/s41598-024-65386-6. PubMed PMID:38918446 PubMed Central PMC11199493.
  12. Verho, L, Aarnio, K, Tikkanen, M, Äyräs, O, Rantanen, K, Korhonen, A et al.. Long-Term Mortality, Recovery, and Vocational Status After a Maternal Stroke: Register-Based Observational Case-Control Study. Neurology. 2024;103 (2):e209532. doi: 10.1212/WNL.0000000000209532. PubMed PMID:38870454 .
  13. Vuoksimaa, E, Saari, TT, Aaltonen, A, Aaltonen, S, Herukka, SK, Iso-Markku, P et al.. TWINGEN: protocol for an observational clinical biobank recall and biomarker cohort study to identify Finnish individuals with high risk of Alzheimer’s disease. BMJ Open. 2024;14 (6):e081947. doi: 10.1136/bmjopen-2023-081947. PubMed PMID:38866570 PubMed Central PMC11177688.
  14. Heinosalo, T, Saarinen, N, Biehl, A, Rytkönen, KT, Villa, PM, Juhila, J et al.. Serum hydroxysteroid (17beta) dehydrogenase 1 concentration in pregnant women correlates with pregnancy-associated plasma protein A but does not serve as an independent marker for preeclampsia†. Biol Reprod. 2024;111 (2):436-447. doi: 10.1093/biolre/ioae078. PubMed PMID:38780059 .
  15. Pohjonen, EM, Huhtala, H, Erkinaro, T, Lehto, J, Pellas, E, Vilmi-Kerälä, T et al.. Risk assessment of hypertensive disorders of pregnancy and other adverse pregnancy outcomes after frozen embryo transfers following an artificial cycle: A retrospective cohort study. Int J Gynaecol Obstet. 2024;167 (2):648-655. doi: 10.1002/ijgo.15689. PubMed PMID:38760967 .
  16. Kivisilta, K, Toivonen, E, Kiverä, A, Kortelainen, E, FINNPEC Core Investigator Group, Uotila, J et al.. Delayed versus early delivery leads to similar outcome in selected cases of preeclampsia in the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC) cohort. Pregnancy Hypertens. 2024;36 :101129. doi: 10.1016/j.preghy.2024.101129. PubMed PMID:38723338 .
  17. Lokki, A, Triebwasser, M, Daly, E, Cohort, F, Kurki, M, Perola, M et al.. Rare variants in genes coding for components of the terminal pathway of the complement system in preeclampsia. Res Sq. 2024; :. doi: 10.21203/rs.3.rs-4121735/v1. PubMed PMID:38645143 PubMed Central PMC11030519.
  18. Pohjonen, EM, Ahinko, K, Huhtala, H, Erkinaro, T, Lehto, J, Pellas, E et al.. Clinical features of preeclampsia and hypertensive disorders in pregnancies after different frozen embryo transfer regimens. Pregnancy Hypertens. 2024;36 :101123. doi: 10.1016/j.preghy.2024.101123. PubMed PMID:38636430 .
  19. Tieu, S, Koivusalo, S, Lahti, J, Engberg, E, Laivuori, H, Huvinen, E et al.. Genetic risk of type 2 diabetes modifies the association between lifestyle and glycemic health at 5 years postpartum among high-risk women. BMJ Open Diabetes Res Care. 2024;12 (2):. doi: 10.1136/bmjdrc-2023-003942. PubMed PMID:38631819 PubMed Central PMC11029483.
  20. Kariniemi, K, Vääräsmäki, M, Männistö, T, Mustaniemi, S, Kajantie, E, Eteläinen, S et al.. Neonatal outcomes according to different glucose threshold values in gestational diabetes: a register-based study. BMC Pregnancy Childbirth. 2024;24 (1):271. doi: 10.1186/s12884-024-06473-4. PubMed PMID:38609891 PubMed Central PMC11010296.
  21. Richardt, A, Aarnio, K, Korhonen, A, Rantanen, K, Verho, L, Curtze, S et al.. Acute recanalization therapy for ischemic stroke during pregnancy and puerperium. J Neurol. 2024;271 (7):4046-4056. doi: 10.1007/s00415-024-12313-4. PubMed PMID:38568226 PubMed Central PMC11233356.
  22. Venkatesh, SS, Wittemans, LBL, Palmer, DS, Baya, NA, Ferreira, T, Hill, B et al.. Genome-wide analyses identify 21 infertility loci and over 400 reproductive hormone loci across the allele frequency spectrum. medRxiv. 2024; :. doi: 10.1101/2024.03.19.24304530. PubMed PMID:38562841 PubMed Central PMC10984039.
  23. Montgomery-Csobán, T, Kavanagh, K, Murray, P, Robertson, C, Barry, SJE, Vivian Ukah, U et al.. Machine learning-enabled maternal risk assessment for women with pre-eclampsia (the PIERS-ML model): a modelling study. Lancet Digit Health. 2024;6 (4):e238-e250. doi: 10.1016/S2589-7500(23)00267-4. PubMed PMID:38519152 PubMed Central PMC10983826.
  24. Kerola, AM, Palomäki, A, Laivuori, H, Laitinen, T, Färkkilä, M, Eklund, KK et al.. Patterns of reproductive health in inflammatory rheumatic diseases and other immune-mediated diseases: a nationwide registry study. Rheumatology (Oxford). 2024;63 (10):2701-2710. doi: 10.1093/rheumatology/keae122. PubMed PMID:38503536 PubMed Central PMC11443019.
  25. de Ruyter, H, Aitokari, L, Lahti, S, Riekki, H, Huhtala, H, Lakka, T et al.. Maternal gestational hypertension, smoking and pre-eclampsia are associated with metabolic dysfunction-associated fatty liver disease in overweight offspring. Acta Obstet Gynecol Scand. 2024;103 (6):1183-1191. doi: 10.1111/aogs.14816. PubMed PMID:38433535 PubMed Central PMC11103127.
  26. Mars, N, Kerminen, S, Tamlander, M, Pirinen, M, Jakkula, E, Aaltonen, K et al.. Comprehensive Inherited Risk Estimation for Risk-Based Breast Cancer Screening in Women. J Clin Oncol. 2024;42 (13):1477-1487. doi: 10.1200/JCO.23.00295. PubMed PMID:38422475 PubMed Central PMC11095905.
  27. Burns, K, Mullin, BH, Moolhuijsen, LME, Laisk, T, Tyrmi, JS, Cui, J et al.. Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry. BMC Genomics. 2024;25 (1):208. doi: 10.1186/s12864-024-09990-w. PubMed PMID:38408933 PubMed Central PMC10895801.
  28. Girchenko, P, Lahti-Pulkkinen, M, Hämäläinen, E, Laivuori, H, Villa, PM, Kajantie, E et al.. Associations of polymetabolic risk of high maternal pre-pregnancy body mass index with pregnancy complications, birth outcomes, and early childhood neurodevelopment: findings from two pregnancy cohorts. BMC Pregnancy Childbirth. 2024;24 (1):78. doi: 10.1186/s12884-024-06274-9. PubMed PMID:38267899 PubMed Central PMC10807109.
  29. Youssef, O, Loukola, A, Zidi-Mouaffak, YHS, Tamlander, M, Ruotsalainen, S, Kilpeläinen, E et al.. High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases. Lab Invest. 2024;104 (4):100325. doi: 10.1016/j.labinv.2024.100325. PubMed PMID:38220043 .
  30. Nurkkala, JM, Aittokallio, J, FinnGen
    , Kauko, A, Niiranen, T. Sex-specific genetic risks for adverse outcomes after coronary revascularization procedures. Interdiscip Cardiovasc Thorac Surg. 2024;38 (1):. doi: 10.1093/icvts/ivae006. PubMed PMID:38216540 PubMed Central PMC10799751.
  31. Toivonen, E, Taurio, K, Kortelainen, E, Havulinna, AS, FINNPEC, Jääskeläinen, T et al.. Validation of the Finnish Care register for Health Care diagnoses for preeclampsia, gestational diabetes and preterm delivery. Pregnancy Hypertens. 2024;35 :26-29. doi: 10.1016/j.preghy.2023.12.001. PubMed PMID:38091805 .
  32. Magnusson, Å, Hanevik, HI, Laivuori, H, Loft, A, Piltonen, T, Pinborg, A et al.. Endometrial preparation protocols prior to frozen embryo transfer – convenience or safety?. Reprod Biomed Online. 2024;48 (1):103587. doi: 10.1016/j.rbmo.2023.103587. PubMed PMID:37949762 .
  33. Renlund, M, Tulppo, MP, Kivelä, A, Laivuori, H, Heinonen, S, Jääskeläinen, T et al.. Preeclampsia-exposed children’s heart rate variability 8-12 yr after index pregnancy: FINNCARE study. Am J Physiol Heart Circ Physiol. 2024;326 (1):H74-H81. doi: 10.1152/ajpheart.00540.2023. PubMed PMID:37921662 PubMed Central PMC11213471.
  34. Lähdepuro, A, Lahti-Pulkkinen, M, Girchenko, P, Villa, PM, Heinonen, K, Lahti, J et al.. Positive maternal mental health during pregnancy and psychiatric problems in children from early childhood to late childhood. Dev Psychopathol. 2024;36 (4):1903-1915. doi: 10.1017/S0954579423001244. PubMed PMID:37814418 .
  35. Vest, T, Rantanen, K, Verho, L, Aarnio, K, Korhonen, A, Richardt, A et al.. Etiology of intracerebral hemorrhage during pregnancy or puerperium: A nationwide study. Eur J Neurol. 2024;31 (3):e16012. doi: 10.1111/ene.16012. PubMed PMID:37532682 PubMed Central PMC11235636.

Search PubMed

2023

  1. Toivonen, E, Taurio, K, Kortelainen, E, Havulinna, AS, FINNPEC, Jääskeläinen, T et al.. Validation of the Finnish Care register for Health Care diagnoses for preeclampsia, gestational diabetes and preterm delivery. Pregnancy Hypertens. 2024;35 :26-29. doi: 10.1016/j.preghy.2023.12.001. PubMed PMID:38091805 .
  2. Lankinen, V, Vuorinen, RL, Helminen, M, Bakti, K, Välipakka, J, Laivuori, H et al.. Costs of abduction treatment in developmental dysplasia of the hip. Analysis of 900 patients. Ann Med. 2023;55 (2):2290694. doi: 10.1080/07853890.2023.2290694. PubMed PMID:38065688 PubMed Central PMC10836239.
  3. Nurmi, AK, Pelttari, LM, Kiiski, JI, Khan, S, Nurmikolu, M, Suvanto, M et al.. NTHL1 is a recessive cancer susceptibility gene. Sci Rep. 2023;13 (1):21127. doi: 10.1038/s41598-023-47441-w. PubMed PMID:38036545 PubMed Central PMC10689455.
  4. Magnusson, Å, Hanevik, HI, Laivuori, H, Loft, A, Piltonen, T, Pinborg, A et al.. Endometrial preparation protocols prior to frozen embryo transfer – convenience or safety?. Reprod Biomed Online. 2024;48 (1):103587. doi: 10.1016/j.rbmo.2023.103587. PubMed PMID:37949762 .
  5. Renlund, M, Tulppo, MP, Kivelä, A, Laivuori, H, Heinonen, S, Jääskeläinen, T et al.. Preeclampsia-exposed children’s heart rate variability 8-12 yr after index pregnancy: FINNCARE study. Am J Physiol Heart Circ Physiol. 2024;326 (1):H74-H81. doi: 10.1152/ajpheart.00540.2023. PubMed PMID:37921662 PubMed Central PMC11213471.
  6. Pasanen, A, Karjalainen, MK, FinnGen, Zhang, G, Tiensuu, H, Haapalainen, AM et al.. Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci. PLoS Genet. 2023;19 (10):e1010982. doi: 10.1371/journal.pgen.1010982. PubMed PMID:37871108 PubMed Central PMC10621942.
  7. Renlund, M, Jääskeläinen, T, Kivelä, A, Heinonen, S, Laivuori, H, Sarkola, T et al.. Determinants of vascular structure and function in at-risk children born to mothers managed for pre-eclampsia (FINNCARE study). Front Cardiovasc Med. 2023;10 :1264921. doi: 10.3389/fcvm.2023.1264921. PubMed PMID:37859683PubMed Central PMC10582712.
  8. Lähdepuro, A, Lahti-Pulkkinen, M, Girchenko, P, Villa, PM, Heinonen, K, Lahti, J et al.. Positive maternal mental health during pregnancy and psychiatric problems in children from early childhood to late childhood. Dev Psychopathol. 2023; :1-13. doi: 10.1017/S0954579423001244. PubMed PMID:37814418 .
  9. Kinnunen, J, Nikkinen, H, Keikkala, E, Mustaniemi, S, Gissler, M, Laivuori, H et al.. Gestational diabetes is associated with the risk of offspring’s congenital anomalies: a register-based cohort study. BMC Pregnancy Childbirth. 2023;23 (1):708. doi: 10.1186/s12884-023-05996-6. PubMed PMID:37789251PubMed Central PMC10548673.
  10. Kivelä, A, Heinonen, S, Kivinen, K, Kere, J, Kajantie, E, Jääskeläinen, T et al.. Hypertensive pregnancy complications and maternal characteristics as predictors of cardiovascular health within ten years after delivery. Pregnancy Hypertens. 2023;34 :5-12. doi: 10.1016/j.preghy.2023.09.001. PubMed PMID:37708664 .
  11. Vuori, MA, Kiiskinen, T, Pitkänen, N, Kurki, S, Laivuori, H, Laitinen, T et al.. Use of electronic health record data mining for heart failure subtyping. BMC Res Notes. 2023;16 (1):208. doi: 10.1186/s13104-023-06469-x. PubMed PMID:37697398 PubMed Central PMC10496250.
  12. Westergaard, D, Steinthorsdottir, V, Stefansdottir, L, Rohde, PD, Wu, X, Geller, F et al.. Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage. medRxiv. 2023; :. doi: 10.1101/2023.08.10.23293932. PubMed PMID:37645979 PubMed Central PMC10462219.
  13. Mustaniemi, S, Keikkala, E, Kajantie, E, Nurhonen, M, Jylhä, A, Morin-Papunen, L et al.. Serum ceramides in early pregnancy as predictors of gestational diabetes. Sci Rep. 2023;13 (1):13274. doi: 10.1038/s41598-023-40224-3. PubMed PMID:37582815 PubMed Central PMC10427660.
  14. Julkunen, V, Schwarz, C, Kalapudas, J, Hallikainen, M, Piironen, AK, Mannermaa, A et al.. A FinnGen pilot clinical recall study for Alzheimer’s disease. Sci Rep. 2023;13 (1):12641. doi: 10.1038/s41598-023-39835-7. PubMed PMID:37537264 PubMed Central PMC10400697.
  15. Vest, T, Rantanen, K, Verho, L, Aarnio, K, Korhonen, A, Richardt, A et al.. Etiology of intracerebral hemorrhage during pregnancy or puerperium: A nationwide study. Eur J Neurol. 2024;31 (3):e16012. doi: 10.1111/ene.16012. PubMed PMID:37532682 PubMed Central PMC11235636.
  16. Viippola, E, Kuitunen, S, Rodosthenous, RS, Vabalas, A, Hartonen, T, Vartiainen, P et al.. Data Resource Profile: Nationwide registry data for high-throughput epidemiology and machine learning (FinRegistry). Int J Epidemiol. 2023;52 (4):e195-e200. doi: 10.1093/ije/dyad091. PubMed PMID:37365732 PubMed Central PMC10396416.
  17. Renlund, MA, Jääskeläinen, TJ, Kivelä, ASE, Heinonen, ST, Laivuori, HM, Sarkola, TA et al.. Blood pressure, arterial stiffness, and cardiovascular risk profiles in 8-12-year-old children following preeclampsia (FINNCARE-study). J Hypertens. 2023;41 (9):1429-1437. doi: 10.1097/HJH.0000000000003485. PubMed PMID:37337860 PubMed Central PMC10399950.
  18. Ågren, R, Patil, S, Zhou, X, FinnGen., Sahlholm, K, Pääbo, S et al.. Major Genetic Risk Factors for Dupuytren’s Disease Are Inherited From Neandertals. Mol Biol Evol. 2023;40 (6):. doi: 10.1093/molbev/msad130. PubMed PMID:37315093 PubMed Central PMC10266526.
  19. Jones, SE, Maisha, FI, Strausz, SJ, Lammi, V, Cade, BE, Tervi, A et al.. The public health impact of poor sleep on severe COVID-19, influenza and upper respiratory infections. EBioMedicine. 2023;93 :104630. doi: 10.1016/j.ebiom.2023.104630. PubMed PMID:37301713 PubMed Central PMC10248098.
  20. Tyrmi, JS, Kaartokallio, T, Lokki, AI, Jääskeläinen, T, Kortelainen, E, Ruotsalainen, S et al.. Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy. JAMA Cardiol. 2023;8 (7):674-683. doi: 10.1001/jamacardio.2023.1312. PubMed PMID:37285119 PubMed Central PMC10248811.
  21. Richardt, A, Aarnio, K, Korhonen, A, Rantanen, K, Verho, L, Laivuori, H et al.. Etiology and risk factors of ischemic stroke during pregnancy and puerperium: A population-based study. Eur Stroke J. 2023;8 (2):475-482. doi: 10.1177/23969873231170096. PubMed PMID:37231685 PubMed Central PMC10334185.
  22. Sormunen-Harju, H, Huvinen, E, Girchenko, PV, Kajantie, E, Villa, PM, Hämäläinen, EK et al.. Metabolomic Profiles of Nonobese and Obese Women With Gestational Diabetes. J Clin Endocrinol Metab. 2023;108 (11):2862-2870. doi: 10.1210/clinem/dgad288. PubMed PMID:37220084 PubMed Central PMC10584006.
  23. Miller, EC, Kauko, A, Tom, SE, Laivuori, H, Niiranen, T, Bello, NA et al.. Risk of Midlife Stroke After Adverse Pregnancy Outcomes: The FinnGen Study. Stroke. 2023;54 (7):1798-1805. doi: 10.1161/STROKEAHA.123.043052. PubMed PMID:37212139 PubMed Central PMC10330298.
  24. Ollila, HM, Sharon, E, Lin, L, Sinnott-Armstrong, N, Ambati, A, Yogeshwar, SM et al.. Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nat Commun. 2023;14 (1):2709. doi: 10.1038/s41467-023-36120-z. PubMed PMID:37188663 PubMed Central PMC10185546.
  25. Lokki, AI, Ren, Z, Triebwasser, M, Daly, E, FINNPEC, Perola, M et al.. Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study. BJOG. 2023;130 (12):1473-1482. doi: 10.1111/1471-0528.17529. PubMed PMID:37156755 PubMed Central PMC10592561.
  26. Verho, L, Tikkanen, M, Äyräs, O, Aarnio, K, Rantanen, K, Korhonen, A et al.. Pregnancy-associated stroke and the recurrence of stroke and other complications in subsequent pregnancies: Population-based retrospective cohort study. BJOG. 2023;130 (11):1421-1429. doi: 10.1111/1471-0528.17503. PubMed PMID:37088716 .
  27. Lankinen, V, Helminen, M, Bakti, K, Välipakka, J, Laivuori, H, Hyvärinen, A et al.. Known risk factors of the developmental dysplasia of the hip predicting more severe clinical presentation and failure of Pavlik harness treatment. BMC Pediatr. 2023;23 (1):148. doi: 10.1186/s12887-023-03935-0. PubMed PMID:37004001 PubMed Central PMC10064754.
  28. Nurkkala, J, Kauko, A, FinnGen,, Laivuori, H, Saarela, T, Tyrmi, JS et al.. Associations of polygenic risk scores for preeclampsia and blood pressure with hypertensive disorders of pregnancy. J Hypertens. 2023;41 (3):380-387. doi: 10.1097/HJH.0000000000003336. PubMed PMID:36947680 PubMed Central PMC9894151.
  29. Koel, M, Võsa, U, Jõeloo, M, Läll, K, Gualdo, NP, Laivuori, H et al.. GWAS meta-analyses clarify the genetics of cervical phenotypes and inform risk stratification for cervical cancer. Hum Mol Genet. 2023;32 (12):2103-2116. doi: 10.1093/hmg/ddad043. PubMed PMID:36929174 PubMed Central PMC10244231.
  30. Rahmioglu, N, Mortlock, S, Ghiasi, M, Møller, PL, Stefansdottir, L, Galarneau, G et al.. The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions. Nat Genet. 2023;55 (3):423-436. doi: 10.1038/s41588-023-01323-z. PubMed PMID:36914876 PubMed Central PMC10042257.
  31. Kurki, MI, Karjalainen, J, Palta, P, Sipilä, TP, Kristiansson, K, Donner, KM et al.. Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population. Nature. 2023;615 (7952):E19. doi: 10.1038/s41586-023-05837-8. PubMed PMID:36829046 PubMed Central PMC10017492.
  32. Sliz, E, Tyrmi, JS, Rahmioglu, N, Zondervan, KT, Becker, CM, FinnGen et al.. Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata. Nat Commun. 2023;14 (1):542. doi: 10.1038/s41467-023-35974-7. PubMed PMID:36726022 PubMed Central PMC9892568.
  33. Kurki, MI, Karjalainen, J, Palta, P, Sipilä, TP, Kristiansson, K, Donner, KM et al.. FinnGen provides genetic insights from a well-phenotyped isolated population. Nature. 2023;613 (7944):508-518. doi: 10.1038/s41586-022-05473-8. PubMed PMID:36653562 PubMed Central PMC9849126.
  34. Mustaniemi, S, Morin-Papunen, L, Keikkala, E, Öhman, H, Surcel, HM, Kaaja, R et al.. Associations of low sex hormone-binding globulin and androgen excess in early pregnancy with fasting and post-prandial hyperglycaemia, gestational diabetes, and its severity. Diabetes Metab Res Rev. 2023;39 (2):e3599. doi: 10.1002/dmrr.3599. PubMed PMID:36484476 PubMed Central PMC10078580.
  35. Korhonen, A, Verho, L, Aarnio, K, Rantanen, K, Saaros, A, Laivuori, H et al.. Subarachnoid Hemorrhage During Pregnancy and Puerperium: A Population-Based Study. Stroke. 2023;54 (1):198-207. doi: 10.1161/STROKEAHA.122.039235. PubMed PMID:36321452 .
  36. Airikka, A, Lahti-Pulkkinen, M, Tuovinen, S, Heinonen, K, Lahti, J, Girchenko, P et al.. Maternal exposure to childhood maltreatment and mental and behavioral disorders in children. Eur Child Adolesc Psychiatry. 2023;32 (12):2463-2475. doi: 10.1007/s00787-022-02090-8. PubMed PMID:36181574 PubMed Central PMC10682113.
  37. Kekki, M, Koukkula, T, Salonen, A, Gissler, M, Laivuori, H, Huttunen, TT et al.. Birth injury in breech delivery: a nationwide population-based cohort study in Finland. Arch Gynecol Obstet. 2023;308 (4):1139-1150. doi: 10.1007/s00404-022-06772-1. PubMed PMID:36074174 PubMed Central PMC10435420.
  38. Kekki, M, Salonen, A, Koukkula, T, Laivuori, H, Tihtonen, K, Huttunen, TT et al.. Incidence changes in risk factors associated with the decreasing number of birth-related clavicle fractures in Finland: A nationwide retrospective birth cohort from 2004 to 2017. Birth. 2023;50 (2):428-437. doi: 10.1111/birt.12662. PubMed PMID:35735132 .
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2022

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2021

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2020

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2019

  1. Girchenko, P, Lahti-Pulkkinen, M, Heinonen, K, Reynolds, RM, Laivuori, H, Lipsanen, J et al.. Persistently High Levels of Maternal Antenatal Inflammation Are Associated With and Mediate the Effect of Prenatal Environmental Adversities on Neurodevelopmental Delay in the Offspring. Biol Psychiatry. 2020;87 (10):898-907. doi: 10.1016/j.biopsych.2019.12.004. PubMed PMID:31987493 .
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  16. Toffol, E, Rantalainen, V, Lahti-Pulkkinen, M, Girchenko, P, Lahti, J, Tuovinen, S et al.. Infant regulatory behavior problems during first month of life and neurobehavioral outcomes in early childhood. Eur Child Adolesc Psychiatry. 2019;28 (6):847-859. doi: 10.1007/s00787-018-1243-8. PubMed PMID:30392118 PubMed Central PMC6555774.
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Search PubMed

2018

  1. Ukah, UV, Payne, B, Karjalainen, H, Kortelainen, E, Seed, PT, Conti-Ramsden, FI et al.. Temporal and external validation of the fullPIERS model for the prediction of adverse maternal outcomes in women with pre-eclampsia. Pregnancy Hypertens. 2019;15 :42-50. doi: 10.1016/j.preghy.2018.01.004. PubMed PMID:30825926 .
  2. Toffol, E, Lahti-Pulkkinen, M, Lahti, J, Lipsanen, J, Heinonen, K, Pesonen, AK et al.. Maternal depressive symptoms during and after pregnancy are associated with poorer sleep quantity and quality and sleep disorders in 3.5-year-old offspring. Sleep Med. 2019;56 :201-210. doi: 10.1016/j.sleep.2018.10.042. PubMed PMID:30819657 .
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  4. Toffol, E, Rantalainen, V, Lahti-Pulkkinen, M, Girchenko, P, Lahti, J, Tuovinen, S et al.. Infant regulatory behavior problems during first month of life and neurobehavioral outcomes in early childhood. Eur Child Adolesc Psychiatry. 2019;28 (6):847-859. doi: 10.1007/s00787-018-1243-8. PubMed PMID:30392118 PubMed Central PMC6555774.
  5. Girchenko, P, Lahti-Pulkkinen, M, Lahti, J, Pesonen, AK, Hämäläinen, E, Villa, PM et al.. Neonatal regulatory behavior problems are predicted by maternal early pregnancy overweight and obesity: findings from the prospective PREDO Study. Pediatr Res. 2018;84 (6):875-881. doi: 10.1038/s41390-018-0199-1. PubMed PMID:30305694 .
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  8. Rönö, K, Stach-Lempinen, B, Eriksson, JG, Pöyhönen-Alho, M, Klemetti, MM, Roine, RP et al.. Prevention of gestational diabetes with a prepregnancy lifestyle intervention – findings from a randomized controlled trial. Int J Womens Health. 2018;10 :493-501. doi: 10.2147/IJWH.S162061. PubMed PMID:30214318 PubMed Central PMC6118269.
  9. Rönö, K, Grotenfelt, NE, Klemetti, MM, Stach-Lempinen, B, Huvinen, E, Meinilä, J et al.. Effect of a lifestyle intervention during pregnancy-findings from the Finnish gestational diabetes prevention trial (RADIEL). J Perinatol. 2018;38 (9):1157-1164. doi: 10.1038/s41372-018-0178-8. PubMed PMID:30042471 .
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  11. Mustaniemi, S, Vääräsmäki, M, Eriksson, JG, Gissler, M, Laivuori, H, Ijäs, H et al.. Polycystic ovary syndrome and risk factors for gestational diabetes. Endocr Connect. 2018;7 (7):859-869. doi: 10.1530/EC-18-0076. PubMed PMID:29858213 PubMed Central PMC6026881.
  12. Jääskeläinen, T, Heinonen, S, Hämäläinen, E, Pulkki, K, Romppanen, J, Laivuori, H et al.. Angiogenic profile in the Finnish Genetics of Pre-Eclampsia Consortium (FINNPEC) cohort. Pregnancy Hypertens. 2018;14 :252-259. doi: 10.1016/j.preghy.2018.03.004. PubMed PMID:29803331 .
  13. Suarez, A, Lahti, J, Czamara, D, Lahti-Pulkkinen, M, Knight, AK, Girchenko, P et al.. The Epigenetic Clock at Birth: Associations With Maternal Antenatal Depression and Child Psychiatric Problems. J Am Acad Child Adolesc Psychiatry. 2018;57 (5):321-328.e2. doi: 10.1016/j.jaac.2018.02.011. PubMed PMID:29706161 PubMed Central PMC6277971.
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  18. Lahti-Pulkkinen, M, Cudmore, MJ, Haeussner, E, Schmitz, C, Pesonen, AK, Hämäläinen, E et al.. Placental Morphology Is Associated with Maternal Depressive Symptoms during Pregnancy and Toddler Psychiatric Problems. Sci Rep. 2018;8 (1):791. doi: 10.1038/s41598-017-19133-9. PubMed PMID:29335435 PubMed Central PMC5768752.
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  20. Kaartokallio, T, Utge, S, Klemetti, MM, Paananen, J, Pulkki, K, Romppanen, J et al.. Fetal Microsatellite in the Heme Oxygenase 1 Promoter Is Associated With Severe and Early-Onset Preeclampsia. Hypertension. 2018;71 (1):95-102. doi: 10.1161/HYPERTENSIONAHA.117.10425. PubMed PMID:29203625 .

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2017

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  7. Jääskeläinen, T, Suomalainen-König, S, Hämäläinen, E, Pulkki, K, Romppanen, J, Heinonen, S et al.. Angiogenic profile and smoking in the Finnish Genetics of Pre-Eclampsia Consortium (FINNPEC) cohort. Ann Med. 2017;49 (7):593-602. doi: 10.1080/07853890.2017.1335427. PubMed PMID:28537456 .
  8. Girchenko, P, Lahti, J, Czamara, D, Knight, AK, Jones, MJ, Suarez, A et al.. Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth. Clin Epigenetics. 2017;9 :49. doi: 10.1186/s13148-017-0349-z. PubMed PMID:28503212 PubMed Central PMC5422977.
  9. Hirvonen, K, Laivuori, H, Lahti, J, Strandberg, T, Eriksson, JG, Hackman, P et al.. SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men. BMC Med Genet. 2017;18 (1):41. doi: 10.1186/s12881-017-0401-z. PubMed PMID:28399814 PubMed Central PMC5387321.
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2016

  1. Jääskeläinen, T, Heinonen, S, Kajantie, E, Kere, J, Kivinen, K, Pouta, A et al.. Cohort profile: the Finnish Genetics of Pre-eclampsia Consortium (FINNPEC). BMJ Open. 2016;6 (11):e013148. doi: 10.1136/bmjopen-2016-013148. PubMed PMID:28067621 PubMed Central PMC5129003.
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