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Infection Biology

Publications

2024

  1. Savijoki, K, Deptula, P, Roberts, RJ, Hammarén, M, Yli-Kauhaluoma, J, Varmanen, P et al.. Revised whole genome and DNA methylome of type strain ATCC 927. Microbiol Resour Announc. 2024;13 (4):e0101623. doi: 10.1128/mra.01016-23. PubMed PMID:38415640 PubMed Central PMC11008211.

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2023

  1. Zapilko, V, Moisio, S, Parikka, M, Heinäniemi, M, Lohi, O. Generation of a Zebrafish Knock-In Model Recapitulating Childhood ETV6::RUNX1-Positive B-Cell Precursor Acute Lymphoblastic Leukemia. Cancers (Basel). 2023;15 (24):. doi: 10.3390/cancers15245821. PubMed PMID:38136366 PubMed Central PMC10871125.
  2. Hammarén, MM, Luukinen, H, Sillanpää, A, Remans, K, Lapouge, K, Custódio, T et al.. and proteomics of biofilms and the development of biofilm-binding synthetic nanobodies. mSystems. 2023;8 (3):e0107322. doi: 10.1128/msystems.01073-22. PubMed PMID:37184670 PubMed Central PMC10308901.
  3. Saralahti, AK, Harjula, SE, Rantapero, T, Uusi-Mäkelä, MIE, Kaasinen, M, Junno, M et al.. Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish. PLoS Genet. 2023;19 (1):e1010586. doi: 10.1371/journal.pgen.1010586. PubMed PMID:36622851 PubMed Central PMC9858863.

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2022

  1. Savijoki, K, San-Martin-Galindo, P, Pitkänen, K, Edelmann, M, Sillanpää, A, van der Velde, C et al.. Food-Grade Bacteria Combat Pathogens by Blocking AHL-Mediated Quorum Sensing and Biofilm Formation. Foods. 2022;12 (1):. doi: 10.3390/foods12010090. PubMed PMID:36613306 PubMed Central PMC9818890.

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2021

  1. Savijoki, K, Myllymäki, H, Luukinen, H, Paulamäki, L, Vanha-Aho, LM, Svorjova, A et al.. Surface-Shaving Proteomics of Mycobacterium marinum Identifies Biofilm Subtype-Specific Changes Affecting Virulence, Tolerance, and Persistence. mSystems. 2021;6 (3):e0050021. doi: 10.1128/mSystems.00500-21. PubMed PMID:34156290 PubMed Central PMC8269238.

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2020

  1. Laukkanen, S, Oksa, L, Nikkilä, A, Lahnalampi, M, Parikka, M, Seki, M et al.. SIX6 is a TAL1-regulated transcription factor in T-ALL and associated with inferior outcome. Leuk Lymphoma. 2020;61 (13):3089-3100. doi: 10.1080/10428194.2020.1804560. PubMed PMID:32835548 .
  2. Immonen, E, Aine, L, Nikkilä, A, Parikka, M, Grönroos, M, Vepsäläinen, K et al.. Randomized controlled and double-blinded study of Caphosol versus saline oral rinses in pediatric patients with cancer. Pediatr Blood Cancer. 2020;67 (10):e28520. doi: 10.1002/pbc.28520. PubMed PMID:32725875 .
  3. Aspatwar, A, Hammaren, M, Parikka, M, Parkkila, S, Carta, F, Bozdag, M et al.. inhibition of -carbonic anhydrase 3 with Mono- and dithiocarbamates and evaluation of their toxicity using zebrafish developing embryos. J Enzyme Inhib Med Chem. 2020;35 (1):65-71. doi: 10.1080/14756366.2019.1683007. PubMed PMID:31663386 PubMed Central PMC6830242.
  4. Harjula, SE, Saralahti, AK, Ojanen, MJT, Rantapero, T, Uusi-Mäkelä, MIE, Nykter, M et al.. Characterization of immune response against Mycobacterium marinum infection in the main hematopoietic organ of adult zebrafish (Danio rerio). Dev Comp Immunol. 2020;103 :103523. doi: 10.1016/j.dci.2019.103523. PubMed PMID:31626817 .

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2019

  1. Aspatwar, A, Kairys, V, Rala, S, Parikka, M, Bozdag, M, Carta, F et al.. Mycobacterium tuberculosisβ-Carbonic Anhydrases: Novel Targets for Developing Antituberculosis Drugs. Int J Mol Sci. 2019;20 (20):. doi: 10.3390/ijms20205153. PubMed PMID:31627429 PubMed Central PMC6834203.
  2. Harjula, SE, Saralahti, AK, Ojanen, MJT, Rantapero, T, Uusi-Mäkelä, MIE, Nykter, M et al.. Characterization of immune response against Mycobacterium marinum infection in the main hematopoietic organ of adult zebrafish (Danio rerio). Dev Comp Immunol. 2020;103 :103523. doi: 10.1016/j.dci.2019.103523. PubMed PMID:31626817 .
  3. Aspatwar, A, Hammaren, MM, Parikka, M, Parkkila, S. Rapid Evaluation of Toxicity of Chemical Compounds Using Zebrafish Embryos. J Vis Exp. 2019; (150):. doi: 10.3791/59315. PubMed PMID:31498322 .
  4. Al-Samadi, A, Tuomainen, K, Kivimäki, A, Salem, A, Al-Kubati, S, Hyytiäinen, A et al.. PCR-based zebrafish model for personalised medicine in head and neck cancer. J Transl Med. 2019;17 (1):235. doi: 10.1186/s12967-019-1985-1. PubMed PMID:31331338 PubMed Central PMC6647158.

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2018

  1. Aspatwar, A, Winum, JY, Carta, F, Supuran, CT, Hammaren, M, Parikka, M et al.. Carbonic Anhydrase Inhibitors as Novel Drugs against Mycobacterial β-Carbonic Anhydrases: An Update on In Vitro and In Vivo Studies. Molecules. 2018;23 (11):. doi: 10.3390/molecules23112911. PubMed PMID:30413024PubMed Central PMC6278287.
  2. Luukinen, H, Hammarén, MM, Vanha-Aho, LM, Parikka, M. Modeling Tuberculosis in Mycobacterium marinum Infected Adult Zebrafish. J Vis Exp. 2018; (140):. doi: 10.3791/58299. PubMed PMID:30346391 PubMed Central PMC6235461.
  3. Aspatwar, A, Becker, HM, Parvathaneni, NK, Hammaren, M, Svorjova, A, Barker, H et al.. Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes. J Enzyme Inhib Med Chem. 2018;33 (1):1064-1073. doi: 10.1080/14756366.2018.1482285. PubMed PMID:29909747 PubMed Central PMC6009478.
  4. Myllymäki, H, Niskanen, M, Luukinen, H, Parikka, M, Rämet, M. Identification of protective postexposure mycobacterial vaccine antigens using an immunosuppression-based reactivation model in the zebrafish. Dis Model Mech. 2018;11 (3):. doi: 10.1242/dmm.033175. PubMed PMID:29590635PubMed Central PMC5897733.
  5. Luukinen, H, Hammarén, MM, Vanha-Aho, LM, Svorjova, A, Kantanen, L, Järvinen, S et al.. Priming of innate antimycobacterial immunity by heat-killed Listeria monocytogenes induces sterilizing response in the adult zebrafish tuberculosis model. Dis Model Mech. 2018;11 (1):. doi: 10.1242/dmm.031658. PubMed PMID:29208761 PubMed Central PMC5818079.

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