Our group is studying how mitochondria control the cell metabolism in health and diseases. In particular, we are interested in the dynamic interaction between respiratory chain activity and cellular metabolic balance, mainly using cell culture models. We approach this goal from three perspectives:
- Influence of the metabolic substrates (MetOnMet)
- Influence of mitochondria-nucleus interactions (MitoHare)
- Influence of the respiratory chain function and dysfunctions (MitoTime)
In addition to providing important fundamental knowledge about metabolic regulations, we hope to clarify and potentially counter the metabolic disturbances caused by mitochondrial diseases.
For respirometry core services, please directly contact E. Dufour