2025
Tujula I, Hyvärinen T, Lotila J, Rogal J, Voulgaris D, Sukki L, Tornberg K, Korpela K, Jäntti H, Malm T, Herland A, Kallio P, Narkilahti S, Hagman S. Human iPSC-based coculture model reveals neuroinflammatory crosstalk between microglia and astrocytes. bioRxiv 2025. doi: https://doi.org/10.1101/2025.01.03.628608
2024
- Juutinen, L, Ahinko, K, Hagman, S, Basnyat, P, Jääskeläinen, O, Herukka, SK et al.. The association of menopausal hormone levels with progression-related biomarkers in multiple sclerosis. Mult Scler Relat Disord. 2024;85 :105517. doi: 10.1016/j.msard.2024.105517. PubMed PMID:38442501 .
Hyvärinen T, Lotila J, Giudice L, Tujula I, Nylund M, Ohtonen S, Scoyni F, Jäntti H, Pihlava S, Skottman H, Narkilahti S, Airas L, Malm T, Hagman S. Microglia from patients with multiple sclerosis display a cell-autonomous immune activation state. bioRxiv 2024. doi: https://doi.org/10.1101/2024.12.10.627477
2022
- Vistbakka, J, Sumelahti, ML, Lehtimäki, T, Hagman, S. Temporal variability of serum miR-191, miR-223, miR-128, and miR-24 in multiple sclerosis: A 4-year follow-up study. J Neurol Sci. 2022;442 :120395. doi: 10.1016/j.jns.2022.120395. PubMed PMID:36084364 .
- Lotila, J, Hyvärinen, T, Skottman, H, Airas, L, Narkilahti, S, Hagman, S et al.. Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient. Stem Cell Res. 2022;63 :102865. doi: 10.1016/j.scr.2022.102865. PubMed PMID:35843021 .
- Mzezewa, R, Lotila, J, Kiiski, H, Vinogradov, A, Kapucu, FE, Peltola, J et al.. A kainic acid-induced seizure model in human pluripotent stem cell-derived cortical neurons for studying the role of IL-6 in the functional activity. Stem Cell Res. 2022;60 :102665. doi: 10.1016/j.scr.2022.102665. PubMed PMID:35091307 .
2021
Mervi Ristola, Chiara Fedele, Sanna Hagman, Lassi Sukki, Emre Kapucu, Ropafadzo Mzezewa, Tanja Hyvärinen, Pasi Kallio, Arri Priimägi, Susanna Narkilahti. Directional Growth of Human Neuronal Axons in a Microfluidic Device with Nanotopography on Azobenzene-Based Material. Advanced Biomaterial Interfaces 2021 DOI: 10.1002/admi.202100048 (Open access))
2020
- Juntunen, M, Hagman, S, Moisan, A, Narkilahti, S, Miettinen, S. Oxygen-Glucose Deprivation-Induced Stroke Models with Human Neuroblastoma Cell- and Induced Pluripotent Stem Cell-Derived Neurons. Stem Cells Int. 2020;2020 :8841026. doi: 10.1155/2020/8841026. PubMed PMID:33178286 PubMed Central PMC7647751.
2019
- Hyvärinen, T, Hagman, S, Ristola, M, Sukki, L, Veijula, K, Kreutzer, J et al.. Co-stimulation with IL-1β and TNF-α induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system. Sci Rep. 2019;9 (1):16944. doi: 10.1038/s41598-019-53414-9. PubMed PMID:31729450 PubMed Central PMC6858358.
- Basnyat, P, Sumelahti, ML, Lehtimäki, T, Elovaara, I, Hagman, S. Gene expression profiles of TNF-like cytokine 1A (TL1A) and its receptors death receptor 3 (DR3) and decoy receptor 3 (DcR3) in multiple sclerosis. J Neuroimmunol. 2019;335 :577020. doi: 10.1016/j.jneuroim.2019.577020. PubMed PMID:31445379 .
- Kolasa, M, Hakulinen, U, Brander, A, Hagman, S, Dastidar, P, Elovaara, I et al.. Diffusion tensor imaging and disability progression in multiple sclerosis: A 4-year follow-up study. Brain Behav. 2019;9 (1):e01194. doi: 10.1002/brb3.1194. PubMed PMID:30588771 PubMed Central PMC6346728.
- Hagman, S, Mäkinen, A, Ylä-Outinen, L, Huhtala, H, Elovaara, I, Narkilahti, S et al.. Effects of inflammatory cytokines IFN-γ, TNF-α and IL-6 on the viability and functionality of human pluripotent stem cell-derived neural cells. J Neuroimmunol. 2019;331 :36-45. doi: 10.1016/j.jneuroim.2018.07.010. PubMed PMID:30195439 .