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Oral Public Health

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Julkaisut

2025

  1. Harmoinen, J, Valtonen, M, Fischer, D, Iso-Touru, T, Åkesson, M, Heikkinen, AM et al.. Development of a cost-effective, multifunctional SNP panel and analysis workflow for Wolf monitoring in Finland. Sci Rep. 2025;15 (1):40816. doi: 10.1038/s41598-025-24502-w. PubMed PMID:41258043 PubMed Central PMC12630743.
  2. Heikkinen, AM, Niku, T, Teronen, E, Linden, J, Kauppila, T. A retrospective registry study comparing a portable school-based model and a standard clinic-based model. Int J Circumpolar Health. 2025;84 (1):2568263. doi: 10.1080/22423982.2025.2568263. PubMed PMID:41066201 PubMed Central PMC12512768.
  3. Haukka, A, Kaila, M, Haukka, J, Heikkinen, AM. Effects of periodontal treatment on periodontal status in Finland: a register-based study. Acta Odontol Scand. 2025;84 :128-136. doi: 10.2340/aos.v84.43232. PubMed PMID:40099982 PubMed Central PMC11971947.

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2024

  1. Heikkinen, AM, Raivisto, T, Räisänen, IT, Sorsa, T. Prevention of Initial Periodontitis Is an Investment in the Future. Diagnostics (Basel). 2024;14 (17):. doi: 10.3390/diagnostics14171850. PubMed PMID:39272635 PubMed Central PMC11394008.

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2023

  1. Heikkinen, AM, Sokka, TT, Torppa-Saarinen, E, Pimiä, E, Jokinen, M, Maijala, M et al.. aMMP-8 Point-of-Care Test (POCT) Identifies Reliably Periodontitis in Patients with Type 2 Diabetes as well as Monitors Treatment Response. Diagnostics (Basel). 2023;13 (13):. doi: 10.3390/diagnostics13132224. PubMed PMID:37443617 PubMed Central PMC10340192.
  2. Haukka, A, Kaila, M, Haukka, J, Heikkinen, AM. Adherence to individualized recall intervals for oral health examinations. Clin Exp Dent Res. 2023;9 (1):177-185. doi: 10.1002/cre2.686. PubMed PMID:36322122 PubMed Central PMC9932253.
  3. Raittio, E, Torppa-Saarinen, E, Sokka, T, Lahti, S, Suominen, A, Suominen, AL et al.. Association of service use with subjective oral health indicators in a freedom of choice pilot. Clin Exp Dent Res. 2023;9 (1):134-141. doi: 10.1002/cre2.680. PubMed PMID:36263738 PubMed Central PMC9932228.

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2022

  1. Pakarinen, S, Saarela, RKT, Välimaa, H, Heikkinen, AM, Kankuri, E, Noponen, M et al.. Home-Applied Dual-Light Photodynamic Therapy in the Treatment of Stable Chronic Periodontitis (HOPE-CP)-Three-Month Interim Results. Dent J (Basel). 2022;10 (11):. doi: 10.3390/dj10110206. PubMed PMID:36354651 PubMed Central PMC9689653.
  2. Haukka, A, Kaila, M, Haukka, J, Heikkinen, AM. Adherence to individualized recall intervals for oral health examinations. Clin Exp Dent Res. 2023;9 (1):177-185. doi: 10.1002/cre2.686. PubMed PMID:36322122 PubMed Central PMC9932253.
  3. Raittio, E, Torppa-Saarinen, E, Sokka, T, Lahti, S, Suominen, A, Suominen, AL et al.. Association of service use with subjective oral health indicators in a freedom of choice pilot. Clin Exp Dent Res. 2023;9 (1):134-141. doi: 10.1002/cre2.680. PubMed PMID:36263738 PubMed Central PMC9932228.
  4. Kallio, J, Heikkinen, AM, Lehtovuori, T, Raina, M, Suominen, L, Kauppila, T et al.. Comparing the effectiveness of competition as a method of reminding primary oral health care dentists to record diagnoses with two alternative methods used to enhance the recording of diagnoses in primary health care. Int J Circumpolar Health. 2022;81 (1):2125067. doi: 10.1080/22423982.2022.2125067. PubMed PMID:36131386 PubMed Central PMC9518279.
  5. Liedes-Kauppila, M, Heikkinen, AM, Rahkonen, O, Lehto, M, Mustonen, K, Raina, M et al.. Development of the use of primary health care emergency departments after interventions aimed at decreasing overcrowding: a longitudinal follow-up study. BMC Emerg Med. 2022;22 (1):108. doi: 10.1186/s12873-022-00667-9. PubMed PMID:35701736 PubMed Central PMC9195435.
  6. Heikkinen, AM, Raivisto, T, Räisänen, I, Tervahartiala, T, Bostanci, N, Sorsa, T et al.. Implementing of aMMP-8 point-of-care test with a modified new disease classification in Finnish adolescent cohorts. Clin Exp Dent Res. 2022;8 (5):1142-1148. doi: 10.1002/cre2.603. PubMed PMID:35676762 PubMed Central PMC9562567.
  7. Kauppila, T, Liedes-Kauppila, M, Lehto, M, Mustonen, K, Rahkonen, O, Raina, M et al.. Development of office-hours use of primary health centers in the early years of the 21 century: a 13-year longitudinal follow-up study. Int J Circumpolar Health. 2022;81 (1):2033405. doi: 10.1080/22423982.2022.2033405. PubMed PMID:35147493 PubMed Central PMC8843247.
  8. Lähteenmäki, H, Tervahartiala, T, Räisänen, IT, Pärnänen, P, Mauramo, M, Gupta, S et al.. Active MMP-8 point-of-care (PoC)/chairside enzyme-test as an adjunctive tool for early and real-time diagnosis of peri-implantitis. Clin Exp Dent Res. 2022;8 (2):485-496. doi: 10.1002/cre2.537. PubMed PMID:35118828 PubMed Central PMC9033547.

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2021

  1. Heikkinen, M, Penttilä, E, Qvarnström, M, Mäkinen, K, Löppönen, H, Kärkkäinen, JM et al.. Patient Self-Assessment and Acoustic Voice Analysis in Screening of Postoperative Vocal Fold Paresis and Paralysis. Scand J Surg. 2021;110 (4):524-532. doi: 10.1177/14574969211007036. PubMed PMID:33843366 PubMed Central PMC8688980.
  2. Räisänen, IT, Sorsa, T, Tervahartiala, T, Raivisto, T, Heikkinen, AM. Low association between bleeding on probing propensity and the salivary aMMP-8 levels in adolescents with gingivitis and stage I periodontitis. J Periodontal Res. 2021;56 (2):289-297. doi: 10.1111/jre.12817. PubMed PMID:33305834 .
  3. Heikkinen, M, Penttilä, E, Qvarnström, M, Mäkinen, K, Löppönen, H, Kärkkäinen, JM et al.. Perceptual Assessment and Acoustic Voice Analysis as Screening Tests for Vocal Fold Paresis After Thyroid or Parathyroid Surgery. World J Surg. 2021;45 (3):765-773. doi: 10.1007/s00268-020-05863-x. PubMed PMID:33249535 PubMed Central PMC7851023.

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2020

  1. Räisänen, IT, Sorsa, T, Tervahartiala, T, Raivisto, T, Heikkinen, AM. Low association between bleeding on probing propensity and the salivary aMMP-8 levels in adolescents with gingivitis and stage I periodontitis. J Periodontal Res. 2021;56 (2):289-297. doi: 10.1111/jre.12817. PubMed PMID:33305834 .
  2. Heikkinen, M, Penttilä, E, Qvarnström, M, Mäkinen, K, Löppönen, H, Kärkkäinen, JM et al.. Perceptual Assessment and Acoustic Voice Analysis as Screening Tests for Vocal Fold Paresis After Thyroid or Parathyroid Surgery. World J Surg. 2021;45 (3):765-773. doi: 10.1007/s00268-020-05863-x. PubMed PMID:33249535 PubMed Central PMC7851023.
  3. Julkunen-Iivari, A, Heikkinen, AM, Räisänen, IT, Ruokonen, H, Meurman, JH, Toppila-Salmi, S et al.. Tobacco Products, Periodontal Health and Education Level: Cohort Study from Sweden. Dent J (Basel). 2020;8 (3):. doi: 10.3390/dj8030090. PubMed PMID:32785107 PubMed Central PMC7559463.
  4. Haukka, A, Heikkinen, AM, Haukka, J, Kaila, M. Oral health indices predict individualised recall interval. Clin Exp Dent Res. 2020;6 (6):585-595. doi: 10.1002/cre2.319. PubMed PMID:32776480 PubMed Central PMC7745075.
  5. Lähteenmäki, H, Umeizudike, KA, Heikkinen, AM, Räisänen, IT, Rathnayake, N, Johannsen, G et al.. aMMP-8 Point-of-Care/Chairside Oral Fluid Technology as a Rapid, Non-Invasive Tool for Periodontitis and Peri-Implantitis Screening in a Medical Care Setting. Diagnostics (Basel). 2020;10 (8):. doi: 10.3390/diagnostics10080562. PubMed PMID:32764436 PubMed Central PMC7460514.
  6. Mattsson, NK, Karjalainen, P, Heikkinen, AM, Nieminen, K, Jalkanen, J, Tolppanen, AM et al.. Agreement between patient global impression scale of improvement, pelvic floor distress inventory and 15D in measuring the outcome of pelvic organ prolapse surgery. Neurourol Urodyn. 2020;39 (8):2171-2178. doi: 10.1002/nau.24467. PubMed PMID:32697861 .
  7. Lehtovuori, T, Heikkinen, AM, Raina, M, Kauppila, T. The effect of electronic reminders on the recording of diagnoses in primary care: A quasi-experimental before and after study. SAGE Open Med. 2020;8 :2050312120918267. doi: 10.1177/2050312120918267. PubMed PMID:32435481 PubMed Central PMC7222644.
  8. Kallio, J, Kauppila, T, Suominen, L, Heikkinen, AM. Recording of diagnoses in public primary oral health care in a retrospective longitudinal observational study in a Finnish town: Underrepresentation of periodontitis diagnoses. Clin Exp Dent Res. 2020;6 (4):457-461. doi: 10.1002/cre2.291. PubMed PMID:32212261 PubMed Central PMC7453766.
  9. Raivisto, T, Heikkinen, AM, Silbereisen, A, Kovanen, L, Ruokonen, H, Tervahartiala, T et al.. Regulation of Salivary Peptidoglycan Recognition Protein 1 in Adolescents. JDR Clin Trans Res. 2020;5 (4):332-341. doi: 10.1177/2380084419894287. PubMed PMID:31860804 .
  10. Silbereisen, A, Alassiri, S, Bao, K, Grossmann, J, Nanni, P, Fernandez, C et al.. Label-Free Quantitative Proteomics versus Antibody-Based Assays to Measure Neutrophil-Derived Enzymes in Saliva. Proteomics Clin Appl. 2020;14 (3):e1900050. doi: 10.1002/prca.201900050. PubMed PMID:31840410 .
  11. Mattsson, NK, Karjalainen, PK, Tolppanen, AM, Heikkinen, AM, Sintonen, H, Härkki, P et al.. Pelvic organ prolapse surgery and quality of life-a nationwide cohort study. Am J Obstet Gynecol. 2020;222 (6):588.e1-588.e10. doi: 10.1016/j.ajog.2019.11.1285. PubMed PMID:31836546 .
  12. Räisänen, IT, Heikkinen, AM, Pakbaznejad Esmaeili, E, Tervahartiala, T, Pajukanta, R, Silbereisen, A et al.. A point-of-care test of active matrix metalloproteinase-8 predicts triggering receptor expressed on myeloid cells-1 (TREM-1) levels in saliva. J Periodontol. 2020;91 (1):102-109. doi: 10.1002/JPER.19-0132. PubMed PMID:31343739 .

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2019

  1. Raivisto, T, Heikkinen, AM, Silbereisen, A, Kovanen, L, Ruokonen, H, Tervahartiala, T et al.. Regulation of Salivary Peptidoglycan Recognition Protein 1 in Adolescents. JDR Clin Trans Res. 2020;5 (4):332-341. doi: 10.1177/2380084419894287. PubMed PMID:31860804 .
  2. Mattsson, NK, Karjalainen, PK, Tolppanen, AM, Heikkinen, AM, Sintonen, H, Härkki, P et al.. Pelvic organ prolapse surgery and quality of life-a nationwide cohort study. Am J Obstet Gynecol. 2020;222 (6):588.e1-588.e10. doi: 10.1016/j.ajog.2019.11.1285. PubMed PMID:31836546 .
  3. Poulsen, H, Meurman, JH, Kautiainen, H, Heikkinen, AM, Huvinen, E, Koivusalo, S et al.. Oral Health in Women with a History of High Gestational Diabetes Risk. Dent J (Basel). 2019;7 (3):. doi: 10.3390/dj7030092. PubMed PMID:31484379 PubMed Central PMC6784739.
  4. Räisänen, IT, Heikkinen, AM, Nwhator, SO, Umeizudike, KA, Tervahartiala, T, Sorsa, T et al.. On the diagnostic discrimination ability of mouthrinse and salivary aMMP-8 point-of-care testing regarding periodontal health and disease. Diagn Microbiol Infect Dis. 2019;95 (4):114871. doi: 10.1016/j.diagmicrobio.2019.114871. PubMed PMID:31473032 .
  5. Lehto, M, Mustonen, K, Kantonen, J, Raina, M, Heikkinen, AK, Kauppila, T et al.. A Primary Care Emergency Service Reduction Did Not Increase Office-Hour Service Use: A Longitudinal Follow-up Study. J Prim Care Community Health. 2019;10 :2150132719865151. doi: 10.1177/2150132719865151. PubMed PMID:31354021 PubMed Central PMC6664635.
  6. Räisänen, IT, Heikkinen, AM, Pakbaznejad Esmaeili, E, Tervahartiala, T, Pajukanta, R, Silbereisen, A et al.. A point-of-care test of active matrix metalloproteinase-8 predicts triggering receptor expressed on myeloid cells-1 (TREM-1) levels in saliva. J Periodontol. 2020;91 (1):102-109. doi: 10.1002/JPER.19-0132. PubMed PMID:31343739 .
  7. Heikkinen, M, Mäkinen, K, Penttilä, E, Qvarnström, M, Kemppainen, T, Löppönen, H et al.. Incidence, Risk Factors, and Natural Outcome of Vocal Fold Paresis in 920 Thyroid Operations with Routine Pre- and Postoperative Laryngoscopic Evaluation. World J Surg. 2019;43 (9):2228-2234. doi: 10.1007/s00268-019-05021-y. PubMed PMID:31065775 .
  8. Räisänen, IT, Sorsa, T, van der Schoor, GJ, Tervahartiala, T, van der Schoor, P, Gieselmann, DR et al.. Active Matrix Metalloproteinase-8 Point-of-Care (PoC)/Chairside Mouthrinse Test vs. Bleeding on Probing in Diagnosing Subclinical Periodontitis in Adolescents. Diagnostics (Basel). 2019;9 (1):. doi: 10.3390/diagnostics9010034. PubMed PMID:30909530 PubMed Central PMC6468891.
  9. Mattsson, NK, Karjalainen, P, Tolppanen, AM, Heikkinen, AM, Jalkanen, J, Härkki, P et al.. Methods of surgery for pelvic organ prolapse in a nationwide cohort (FINPOP 2015). Acta Obstet Gynecol Scand. 2019;98 (4):451-459. doi: 10.1111/aogs.13520. PubMed PMID:30578530 .
  10. Heikkinen, AM, Räisänen, IT, Tervahartiala, T, Sorsa, T. Cross-sectional analysis of risk factors for subclinical periodontitis; active matrix metalloproteinase-8 as a potential indicator in initial periodontitis in adolescents. J Periodontol. 2019;90 (5):484-492. doi: 10.1002/JPER.18-0450. PubMed PMID:30397915 .
  11. Heikkinen, M, Halttunen, S, Terävä, M, Kärkkäinen, JM, Löppönen, H, Penttilä, E et al.. Vocal foldparesis as a surgical complication: Our 10-year experience with 162 incidents. Clin Otolaryngol. 2019;44 (2):179-182. doi: 10.1111/coa.13251. PubMed PMID:30369057 .
  12. Ruokonen, H, Nylund, K, Meurman, JH, Heikkinen, AM, Furuholm, J, Sorsa, T et al.. Oral symptoms and oral health-related quality of life in patients with chronic kidney disease from predialysis to posttransplantation. Clin Oral Investig. 2019;23 (5):2207-2213. doi: 10.1007/s00784-018-2647-z. PubMed PMID:30276517 .

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2018

  1. Heikkinen, AM, Räisänen, IT, Tervahartiala, T, Sorsa, T. Cross-sectional analysis of risk factors for subclinical periodontitis; active matrix metalloproteinase-8 as a potential indicator in initial periodontitis in adolescents. J Periodontol. 2019;90 (5):484-492. doi: 10.1002/JPER.18-0450. PubMed PMID:30397915 .
  2. Heikkinen, M, Halttunen, S, Terävä, M, Kärkkäinen, JM, Löppönen, H, Penttilä, E et al.. Vocal foldparesis as a surgical complication: Our 10-year experience with 162 incidents. Clin Otolaryngol. 2019;44 (2):179-182. doi: 10.1111/coa.13251. PubMed PMID:30369057 .
  3. Räisänen, IT, Heikkinen, AM, Siren, E, Tervahartiala, T, Gieselmann, DR, van der Schoor, GJ et al.. Point-of-Care/Chairside aMMP-8 Analytics of Periodontal Diseases’ Activity and Episodic Progression. Diagnostics (Basel). 2018;8 (4):. doi: 10.3390/diagnostics8040074. PubMed PMID:30360358 PubMed Central PMC6315514.
  4. Ruokonen, H, Nylund, K, Meurman, JH, Heikkinen, AM, Furuholm, J, Sorsa, T et al.. Oral symptoms and oral health-related quality of life in patients with chronic kidney disease from predialysis to posttransplantation. Clin Oral Investig. 2019;23 (5):2207-2213. doi: 10.1007/s00784-018-2647-z. PubMed PMID:30276517 .
  5. Alassiri, S, Parnanen, P, Rathnayake, N, Johannsen, G, Heikkinen, AM, Lazzara, R et al.. The Ability of Quantitative, Specific, and Sensitive Point-of-Care/Chair-Side Oral Fluid Immunotests for aMMP-8 to Detect Periodontal and Peri-Implant Diseases. Dis Markers. 2018;2018 :1306396. doi: 10.1155/2018/1306396. PubMed PMID:30154936 PubMed Central PMC6098860.
  6. Äyräväinen, L, Heikkinen, AM, Kuuliala, A, Ahola, K, Koivuniemi, R, Peltola, J et al.. Activity of rheumatoid arthritis correlates with oral inflammatory burden. Rheumatol Int. 2018;38 (9):1661-1669. doi: 10.1007/s00296-018-4108-z. PubMed PMID:30043237 .
  7. Äyräväinen, L, Heikkinen, AM, Kuuliala, A, Ahola, K, Koivuniemi, R, Moilanen, E et al.. Anti-rheumatic medication and salivary MMP-8, a biomarker for periodontal disease. Oral Dis. 2018;24 (8):1562-1571. doi: 10.1111/odi.12930. PubMed PMID:29969841 .
  8. Raivisto, T, Heikkinen, A, Kovanen, L, Ruokonen, H, Kettunen, K, Tervahartiala, T et al.. SNP Analysis of Caries and Initial Caries in Finnish Adolescents. Int J Dent. 2018;2018 :1586762. doi: 10.1155/2018/1586762. PubMed PMID:29849633 PubMed Central PMC5937374.
  9. Äyräväinen, L, Heikkinen, AM, Kuuliala, A, Ahola, K, Koivuniemi, R, Laasonen, L et al.. Inflammatory biomarkers in saliva and serum of patients with rheumatoid arthritis with respect to periodontal status. Ann Med. 2018;50 (4):333-344. doi: 10.1080/07853890.2018.1468922. PubMed PMID:29683364 .
  10. Lehtovuori, T, Kauppila, T, Kallio, J, Heikkinen, AM, Raina, M, Suominen, L et al.. Improving the Recording of Diagnoses in Primary Care with Team Incentives: A Controlled Longitudinal Follow-Up Study. Biomed Res Int. 2018;2018 :4606710. doi: 10.1155/2018/4606710. PubMed PMID:29675425 PubMed Central PMC5838484.
  11. Nylund, KM, Ruokonen, H, Sorsa, T, Heikkinen, AM, Meurman, JH, Ortiz, F et al.. Association of the salivary triggering receptor expressed on myeloid cells/its ligand peptidoglycan recognition protein 1 axis with oral inflammation in kidney disease. J Periodontol. 2018;89 (1):117-129. doi: 10.1902/jop.2017.170218. PubMed PMID:28846062 .
  12. Nylund, KM, Meurman, JH, Heikkinen, AM, Furuholm, JO, Ortiz, F, Ruokonen, HM et al.. Oral health in patients with renal disease: a longitudinal study from predialysis to kidney transplantation. Clin Oral Investig. 2018;22 (1):339-347. doi: 10.1007/s00784-017-2118-y. PubMed PMID:28424878 .

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