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Palliative Medicine

TUNI Palliative Care Research Group

Publications

2024

  1. Tolvanen, E, Piili, RP, Louhiala, P, Hökkä, M, Vänskä, J, Lehto, JT et al.. Content validity of the questionnaire considering opinions of the Finnish physicians on euthanasia and assisted suicide. Sci Rep. 2024;14 (1):29190. doi: 10.1038/s41598-024-79803-3. PubMed PMID:39587199 PubMed Central PMC11589865.
  2. Jaakkola, E, Piili, RP, Lehto, JT, Tolvanen, E. Integrated palliative care visits of patients with incurable cancer in Tampere University Hospital 2018-2021-a retrospective study. Ann Palliat Med. 2024;13 (6):1353-1361. doi: 10.21037/apm-24-71. PubMed PMID:39390910 .
  3. Rautajoki, T, Rantala, HA, Sutinen, E, Saarto, T, Rajala, K, Pesonen, I et al.. Health-related quality of life measured with K-BILD is associated with survival in patients with idiopathic pulmonary fibrosis. BMC Pulm Med. 2024;24 (1):480. doi: 10.1186/s12890-024-03303-3. PubMed PMID:39350048 PubMed Central PMC11443770.
  4. Piili, RP, Hökkä, M, Vänskä, J, Tolvanen, E, Louhiala, P, Lehto, JT et al.. Facing a request for assisted death – views of Finnish physicians, a mixed method study. BMC Med Ethics. 2024;25 (1):50. doi: 10.1186/s12910-024-01051-x. PubMed PMID:38702731 PubMed Central PMC11067268.
  5. Pesonen, E, Vuorinen, P, Surakka, L, Lehto, JT, Hoppu, S. Palliative care patients in the emergency medical service: a retrospective cohort study from Finland. BMC Health Serv Res. 2024;24 (1):543. doi: 10.1186/s12913-024-10905-4. PubMed PMID:38685064 PubMed Central PMC11057072.
  6. Aho, S, Osterlund, E, Ristimäki, A, Nieminen, L, Sundström, J, Mäkinen, MJ et al.. Impact of Primary Tumor Location on Demographics, Resectability, Outcomes, and Quality of Life in Finnish Metastatic Colorectal Cancer Patients (Subgroup Analysis of the RAXO Study). Cancers (Basel). 2024;16 (5):. doi: 10.3390/cancers16051052. PubMed PMID:38473410 PubMed Central PMC10931274.

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2023
  1. Haltia, O, Vesinurm, M, Leskelä, RL, Rahko, E, Tyynelä-Korhonen, K, Lehto, JT et al.. The effect of palliative outpatient units on resource use for cancer patients in Finland. Acta Oncol. 2023;62 (9):1118-1123. doi: 10.1080/0284186X.2023.2241988. PubMed PMID:37535611 .
  2. Haapasalmi, S, Lehto, JT, Metsänoja, R, Kellokumpu-Lehtinen, PI, Piili, RP. End-of-life Decision-making Differs Between a Cancer and a Dementia Patient: Influences of the Physician’s Background Factors. Anticancer Res. 2023;43 (8):3631-3638. doi: 10.21873/anticanres.16543. PubMed PMID:37500170 .
  3. Rautajoki, T, Lehto, JT, Sutinen, E, Bergman, P, Sintonen, H, Rajala, K et al.. Dyspnea Associates With a Widely Impaired Quality of Life in Idiopathic Pulmonary Fibrosis Patients: A Longitudinal Study Using 15D. J Palliat Med. 2023;26 (10):1357-1364. doi: 10.1089/jpm.2022.0548. PubMed PMID:37366772 .
  4. Leivo-Korpela, S, Rantala, HA, Piili, RP, Lehtimäki, L, Lehto, JT. Palliation of Dyspnea With Mouthpiece Ventilation in Patients With Chronic Obstructive Pulmonary Disease: A Pilot Feasibility Study. J Palliat Med. 2023;26 (9):1261-1265. doi: 10.1089/jpm.2023.0039. PubMed PMID:37155710 .
  5. Pihlaja, H, Rantala, H, Leivo-Korpela, S, Lehtimäki, L, Lehto, JT, Piili, RP et al.. Specialist Palliative Care Consultation for Patients with Nonmalignant Pulmonary Diseases: A Retrospective Study. Palliat Med Rep. 2023;4 (1):108-115. doi: 10.1089/pmr.2022.0068. PubMed PMID:37095866 PubMed Central PMC10122226.
  6. Viitala, A, Åstedt-Kurki, P, Lehto, JT, Palonen, M. ‘I am still valuable’ – A qualitative study of incurable cancer patients coping in hospice care. Scand J Caring Sci. 2023;37 (3):720-731. doi: 10.1111/scs.13160. PubMed PMID:36852620 .
  7. Rouhento, EAS, Lehto, JT, Kalliomäki, ML. Peripheral nerve blocks in advanced cancer pain: retrospective case series. BMJ Support Palliat Care. 2023;13 (e2):e287-e290. doi: 10.1136/bmjspcare-2021-003293. PubMed PMID:34857538 .

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2022
  1. Surakka, LK, Hökkä, M, Törrönen, K, Mäntyselkä, P, Lehto, JT. Paramedics’ experiences and educational needs when participating end-of-life care at home: A mixed method study. Palliat Med. 2022;36 (8):1217-1227. doi: 10.1177/02692163221105593. PubMed PMID:35922966 .
  2. Piili, RP, Louhiala, P, Vänskä, J, Lehto, JT. Ambivalence toward euthanasia and physician-assisted suicide has decreased among physicians in Finland. BMC Med Ethics. 2022;23 (1):71. doi: 10.1186/s12910-022-00810-y. PubMed PMID:35820881 PubMed Central PMC9275272.
  3. Hökkä, M, Rajala, M, Kaakinen, P, Lehto, JT, Pesonen, HM. The effect of teaching methods in palliative care education for undergraduate nursing and medical students: a systematic review. Int J Palliat Nurs. 2022;28 (6):245-253. doi: 10.12968/ijpn.2022.28.6.245. PubMed PMID:35727833 .
  4. Laitamäki, M, Tyrväinen, T, Lehto, JT, Laukkarinen, J, Ukkonen, M. Endoscopic duodenal stenting is efficient, but has higher rate of reoperations than gastrojejunostomy in palliative treatment for gastric outlet obstruction. Langenbecks Arch Surg. 2022;407 (6):2509-2515. doi: 10.1007/s00423-022-02565-x. PubMed PMID:35648229 PubMed Central PMC9468122.
  5. Hökkä, M, Lehto, JT, Kyngäs, H, Pölkki, T. Finnish nursing students’ perceptions of the development needs in palliative care education and factors influencing learning in undergraduate nursing studies – a qualitative study. BMC Palliat Care. 2022;21 (1):40. doi: 10.1186/s12904-022-00915-6. PubMed PMID:35321718 PubMed Central PMC8940965.
  6. Hökkä, M, Pölkki, T, Lehto, JT. Nursing Students’ Views of the Content of Palliative Care in Undergraduate Education and their Self-assessed Palliative Care Competence-A Nationwide Cross-sectional Study. J Palliat Care. 2022;37 (3):434-442. doi: 10.1177/08258597221084445. PubMed PMID:35286180 .
  7. Melender, HL, Hökkä, M, Kaakinen, P, Lehto, JT, Hirvonen, O. Palliative-care nurses’ and physicians’ descriptions of the competencies needed in their working units. Int J Palliat Nurs. 2022;28 (1):38-50. doi: 10.12968/ijpn.2022.28.1.38. PubMed PMID:35094532 .
  8. Rantala, HA, Leivo-Korpela, S, Lehtimäki, L, Lehto, JT. Assessing Symptom Burden and Depression in Subjects With Chronic Respiratory Insufficiency. J Palliat Care. 2022;37 (2):134-141. doi: 10.1177/08258597211049592. PubMed PMID:34841962 PubMed Central PMC9109583.

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Lehtomäki, K, Stedt, HP, Osterlund, E, Muhonen, T, Soveri, LM, Halonen, P et al.. Health-Related Quality of Life in Metastatic Colorectal Cancer Patients Treated with Curative Resection and/or Local Ablative Therapy or Systemic Therapy in the Finnish RAXO-Study. Cancers (Basel). 2022;14 (7):. doi: 10.3390/cancers14071713. PubMed PMID:35406485 PubMed Central PMC8996978.

2021
  1. Rantala, HA, Leivo-Korpela, S, Lehtimäki, L, Lehto, JT. Assessing Symptom Burden and Depression in Subjects With Chronic Respiratory Insufficiency. J Palliat Care. 2022;37 (2):134-141. doi: 10.1177/08258597211049592. PubMed PMID:34841962 PubMed Central PMC9109583.
  2. Viitala, A, Åstedt-Kurki, P, Lehto, JT, Palonen, M. Online follow-up with a mobile device improves incurable cancer patients’ coping – A qualitative study. Eur J Oncol Nurs. 2021;55 :102047. doi: 10.1016/j.ejon.2021.102047. PubMed PMID:34688053 .
  3. Haapasalmi, S, Piili, RP, Metsänoja, R, Kellokumpu-Lehtinen, PI, Lehto, JT. Physicians’ decreased tendency to choose palliative care for patients with advanced dementia between 1999 and 2015. BMC Palliat Care. 2021;20 (1):119. doi: 10.1186/s12904-021-00811-5. PubMed PMID:34311739 PubMed Central PMC8312352.
  4. Murtonen, A, Lehto, JT, Sumelahti, ML. End of life in multiple sclerosis: Disability, causes and place of death among cases diagnosed from 1981 to 2010 in Pirkanmaa hospital district in Western Finland. Mult Scler Relat Disord. 2021;54 :103139. doi: 10.1016/j.msard.2021.103139. PubMed PMID:34273609 .
  5. Rantala, HA, Leivo-Korpela, S, Lehto, JT, Lehtimäki, L. Dyspnea on Exercise Is Associated with Overall Symptom Burden in Patients with Chronic Respiratory Insufficiency. Palliat Med Rep. 2021;2 (1):48-53. doi: 10.1089/pmr.2020.0112. PubMed PMID:34223503 PubMed Central PMC8241384.
  6. Haltia, O, Hirvonen, OM, Saarto, T, Lehto, JT. Impact of the Regional Palliative Care Pathway on Emergency Room Visits and Hospitalizations. Anticancer Res. 2021;41 (3):1701-1706. doi: 10.21873/anticanres.14934. PubMed PMID:33788768 .
  7. Hökkä, M, Melender, HL, Lehto, JT, Kaakinen, P. Palliative Nursing Competencies Required for Different Levels of Palliative Care Provision: A Qualitative Analysis of Health Care Professionals’ Perspectives. J Palliat Med. 2021;24 (10):1516-1524. doi: 10.1089/jpm.2020.0632. PubMed PMID:33720785 PubMed Central PMC8590151.
  8. Surakka, LK, Peake, MM, Kiljunen, MM, Mäntyselkä, P, Lehto, JT. Preplanned participation of paramedics in end-of-life care at home: A retrospective cohort study. Palliat Med. 2021;35 (3):584-591. doi: 10.1177/0269216320981713. PubMed PMID:33339483 .

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2020
  1. Surakka, LK, Peake, MM, Kiljunen, MM, Mäntyselkä, P, Lehto, JT. Preplanned participation of paramedics in end-of-life care at home: A retrospective cohort study. Palliat Med. 2021;35 (3):584-591. doi: 10.1177/0269216320981713. PubMed PMID:33339483 .
  2. Rantala, HA, Leivo-Korpela, S, Kettunen, S, Lehto, JT, Lehtimäki, L. Survival and end-of-life aspects among subjects on long-term noninvasive ventilation. Eur Clin Respir J. 2020;8 (1):1840494. doi: 10.1080/20018525.2020.1840494. PubMed PMID:33209213 PubMed Central PMC7646568.
  3. Seppälä, S, Rajala, K, Lehto, JT, Sutinen, E, Mäkitalo, L, Kautiainen, H et al.. Factor analysis identifies three separate symptom clusters in idiopathic pulmonary fibrosis. ERJ Open Res. 2020;6 (4):. doi: 10.1183/23120541.00347-2020. PubMed PMID:33043051 PubMed Central PMC7533377.
  4. Lehto, JT, Leivo-Korpela, S, Korhonen, T, Rantala, HA, Raunio, H, Lyly-Yrjänäinen, T et al.. Mouthpiece ventilation in the management of dyspnea: A single-arm pilot study. Palliat Med. 2020;34 (9):1274-1278. doi: 10.1177/0269216320935003. PubMed PMID:32579086 PubMed Central PMC7495670.
  5. Melender, HL, Hökkä, M, Saarto, T, Lehto, JT. The required competencies of physicians within palliative care from the perspectives of multi-professional expert groups: a qualitative study. BMC Palliat Care. 2020;19 (1):65. doi: 10.1186/s12904-020-00566-5. PubMed PMID:32386513 PubMed Central PMC7211329.
  6. Hirvonen, OM, Leskelä, RL, Grönholm, L, Haltia, O, Voltti, S, Tyynelä-Korhonen, K et al.. The impact of the duration of the palliative care period on cancer patients with regard to the use of hospital services and the place of death: a retrospective cohort study. BMC Palliat Care. 2020;19 (1):37. doi: 10.1186/s12904-020-00547-8. PubMed PMID:32209075 PubMed Central PMC7093948.

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2019
  1. Hirvonen, OM, Leskelä, RL, Grönholm, L, Haltia, O, Rissanen, A, Tyynelä-Korhonen, K et al.. Assessing the utilization of the decision to implement a palliative goal for the treatment of cancer patients during the last year of life at Helsinki University Hospital: a historic cohort study. Acta Oncol. 2019;58 (12):1699-1705. doi: 10.1080/0284186X.2019.1659512. PubMed PMID:31742490 .
  2. Piili, RP, Lehto, JT, Metsänoja, R, Hinkka, H, Kellokumpu-Lehtinen, PI. Has there been a change in the end-of-life decision-making over the past 16 years?. BMJ Support Palliat Care. 2019; :. doi: 10.1136/bmjspcare-2019-001802. PubMed PMID:31395612 .
  3. Alminoja, A, Piili, RP, Hinkka, H, Metsänoja, R, Hirvonen, O, Tyynelä-Korhonen, K et al.. Does Decision-making in End-of-life Care Differ Between Graduating Medical Students and Experienced Physicians?. In Vivo. ;33 (3):903-909. doi: 10.21873/invivo.11557. PubMed PMID:31028215 PubMed Central PMC6559926.
  4. Rantala, HA, Leivo-Korpela, S, Lehtimäki, L, Lehto, JT. Predictors of Impaired Survival in Subjects With Long-Term Oxygen Therapy. Respir Care. 2019;64 (11):1401-1409. doi: 10.4187/respcare.06615. PubMed PMID:30914489 .
  5. Kokkonen, K, Tasmuth, T, Lehto, JT, Kautiainen, H, Elme, A, Jääskeläinen, AS et al.. Cancer Patients’ Symptom Burden and Health-related Quality of Life (HRQoL) at Tertiary Cancer Center from 2006 to 2013: A Cross-sectional Study. Anticancer Res. 2019;39 (1):271-277. doi: 10.21873/anticanres.13107. PubMed PMID:30591468 .
  6. Terkamo-Moisio, A, Pietilä, AM, Lehto, JT, Ryynänen, OP. Attitudes of Nurses and the General Public Towards Euthanasia on Individuals with Dementia and Cognitive Impairment. Dementia (London). 2019;18 (4):1466-1478. doi: 10.1177/1471301217717063. PubMed PMID:28699366 .

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2018
  1. Rajala, K, Lehto, JT, Sutinen, E, Kautiainen, H, Myllärniemi, M, Saarto, T et al.. Marked deterioration in the quality of life of patients with idiopathic pulmonary fibrosis during the last two years of life. BMC Pulm Med. 2018;18 (1):172. doi: 10.1186/s12890-018-0738-x. PubMed PMID:30458739 PubMed Central PMC6247520.
  2. Koski, K, Lehto, JT, Hakkarainen, K. Simulated Encounters With Vaccine-Hesitant Parents: Arts-Based Video Scenario and a Writing Exercise. J Med Educ Curric Dev. ;5 :2382120518790257. doi: 10.1177/2382120518790257. PubMed PMID:30090864 PubMed Central PMC6077885.
  3. Viitala, A, Saukkonen, M, Lehto, JT, Palonen, M, Åstedt-Kurki, P. The Coping and Support Needs of Incurable Cancer Patients. J Hosp Palliat Nurs. 2018;20 (2):187-194. doi: 10.1097/NJH.0000000000000427. PubMed PMID:30063573 .
  4. Piili, RP, Lehto, JT, Luukkaala, T, Hinkka, H, Kellokumpu-Lehtinen, PI. Does special education in palliative medicine make a difference in end-of-life decision-making?. BMC Palliat Care. 2018;17 (1):94. doi: 10.1186/s12904-018-0349-6. PubMed PMID:30021586 PubMed Central PMC6052558.
  5. Piili, RP, Metsänoja, R, Hinkka, H, Kellokumpu-Lehtinen, PI, Lehto, JT. Changes in attitudes towards hastened death among Finnish physicians over the past sixteen years. BMC Med Ethics. 2018;19 (1):40. doi: 10.1186/s12910-018-0290-5. PubMed PMID:29843682 PubMed Central PMC5975714.
  6. Korpi, S, Salminen, VV, Piili, RP, Paunu, N, Luukkaala, T, Lehto, JT et al.. Therapeutic Procedures for Malignant Ascites in a Palliative Care Outpatient Clinic. J Palliat Med. 2018;21 (6):836-841. doi: 10.1089/jpm.2017.0616. PubMed PMID:29489450 .
  7. Haltia, O, Färkkilä, N, Roine, RP, Sintonen, H, Taari, K, Hänninen, J et al.. The indirect costs of palliative care in end-stage cancer: A real-life longitudinal register- and questionnaire-based study. Palliat Med. 2018;32 (2):493-499. doi: 10.1177/0269216317729789. PubMed PMID:28895471 .

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