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Physiological Measurement Systems and Methods

Group leader: Assistant Professor Jari Viik

Latest publications

2026

  1. Karppa, E, Puura, K, Jyskä, I, Viik, J, Pohjankoski, H, Turunen, M et al.. VR-guided deep breathing during needle procedures in children. Sci Rep. 2026;16 (1):. doi: 10.1038/s41598-026-44390-y. PubMed PMID:41865162 PubMed Central PMC13144402.
  2. Pulkkanen, M, Ochoa, JÁ, Reito, A, Eskelinen, A, Viik, J, Hyttinen, J et al.. Effect of liner geometry on jumping distance: as relevant as head size. BMC Musculoskelet Disord. 2026;27 (1):. doi: 10.1186/s12891-026-09688-y. PubMed PMID:41787317 PubMed Central PMC13069717.
  3. Lähteenmäki, S, Juutinen, M, Viik, J, Mahrberg, H, Laurikka, J. Effects of physiotherapy on breathing cycle after thoracic surgery measured with impedance pneumography in a prospective clinical comparison. Gen Thorac Cardiovasc Surg. 2026;74 (3):286-294. doi: 10.1007/s11748-025-02199-y. PubMed PMID:41004114 PubMed Central PMC12956966.

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2025

  1. Lähteenmäki, S, Juutinen, M, Viik, J, Mahrberg, H, Laurikka, J. Effects of physiotherapy on breathing cycle after thoracic surgery measured with impedance pneumography in a prospective clinical comparison. Gen Thorac Cardiovasc Surg. 2026;74 (3):286-294. doi: 10.1007/s11748-025-02199-y. PubMed PMID:41004114 PubMed Central PMC12956966.
  2. Antoszewska, M, Połomska, K, Spychalski, P, Kekonen, A, Viik, J, Barańska-Rybak, W et al.. Bioimpedance Measurement for Monitoring Chronic Wounds: A Systematic Review. Int Wound J. 2025;22 (6):e70707. doi: 10.1111/iwj.70707. PubMed PMID:40505690 PubMed Central PMC12162137.

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2024
  1. Enroth, M, Sievanen, H, Asikainen, TTA, Viik, J. Use of ST/HR hysteresis decreases false positive rate in exercise electrocardiography test of middle-aged asymptomatic women. J Electrocardiol. 2024;87 :153820. doi: 10.1016/j.jelectrocard.2024.153820. PubMed PMID:39504597 .
  2. Ochoa, JÁ, Neuvonen, PS, Hyttinen, J, Viik, J, Eskelinen, AP. Are some neutral liners more neutral than others? An ex vivo morphological analysis of acetabular liners classified as “neutral”. Acta Orthop. 2024;95 :586-591. doi: 10.2340/17453674.2024.41946. PubMed PMID:39392408 PubMed Central PMC11468231.
  3. Antoszewska, M, Spychalski, P, Kekonen, A, Viik, J, Barańska-Rybak, W. Bioimpedance sensor array for monitoring chronic wounds: Validation of method feasibility. Int Wound J. 2024;21 (8):e14899. doi: 10.1111/iwj.14899. PubMed PMID:39099180 PubMed Central PMC11298616.
  4. Hernesniemi, JA, Pukkila, T, Molkkari, M, Nikus, K, Lyytikäinen, LP, Lehtimäki, T et al.. Prediction of Sudden Cardiac Death With Ultra-Short-Term Heart Rate Fluctuations. JACC Clin Electrophysiol. 2024;10 (9):2010-2020. doi: 10.1016/j.jacep.2024.04.018. PubMed PMID:38878016 .
  5. Perez, C, Pueyo, E, Martinez, JP, Viik, J, Sornmo, L, Laguna, P et al.. Performance Evaluation of QT-RR Adaptation Time Lag Estimation in Exercise Stress Testing. IEEE Trans Biomed Eng. 2024;71 (11):3170-3180. doi: 10.1109/TBME.2024.3410008. PubMed PMID:38837931 .

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2023

Jyskä, I, Turunen, M, Chaychi Maleki, A, Karppa, E, Palmu, S, Viik, J et al.. Effects of Using Guided Deep Breathing Exercises in a Virtual Natural Environment to Reduce Stress during Pediatric Treatment. Healthcare (Basel). 2023;11 (24):. doi: 10.3390/healthcare11243140. PubMed PMID:38132030 PubMed Central PMC10743274.
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2022
  1. Koskela, JK, Tahvanainen, A, Tikkakoski, AJ, Kangas, P, Uitto, M, Viik, J et al.. Resting heart rate predicts cardiac autonomic modulation during passive head-up tilt in subjects without cardiovascular diseases. Scand Cardiovasc J. 2022;56 (1):138-147. doi: 10.1080/14017431.2022.2079713. PubMed PMID:35652524 .
  2. Beyene, SD, Nikus, KC, Lehtimäki, TJ, Kähönen, MAP, Viik, JJ. Evaluation of the QRS score for diagnosing coronary artery disease in women: A Finnish cardiovascular study. Ann Noninvasive Electrocardiol. 2022;27 (4):e12968. doi: 10.1111/anec.12968. PubMed PMID:35580147 PubMed Central PMC9296785.

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2021
  1. Del Castillo, MG, Hernando, D, Orini, M, Laguna, P, Viik, J, Bailón, R et al.. QT variability unrelated to RR variability during stress testing for identification of coronary artery disease. Philos Trans A Math Phys Eng Sci. 2021;379 (2212):20200261. doi: 10.1098/rsta.2020.0261. PubMed PMID:34689618 .
  2. Suojanen, LJ, Koskela, JK, Wilenius, M, Choudhary, MK, Hautaniemi, EJ, Viik, J et al.. Individual changes of central blood pressure in response to upright posture: different hemodynamic phenotypes. J Hypertens. 2021;39 (12):2403-2412. doi: 10.1097/HJH.0000000000002965. PubMed PMID:34269331 .
  3. Kekonen, A, Bergelin, M, Eriksson, JE, Vaalasti, A, Ylänen, H, Kielosto, S et al.. Bioimpedance method for monitoring venous ulcers: Clinical proof-of-concept study. Biosens Bioelectron. 2021;178 :112974. doi: 10.1016/j.bios.2021.112974. PubMed PMID:33524705 .

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2020
  1. Seppä, VP, Gracia-Tabuenca, J, Kotaniemi-Syrjänen, A, Malmström, K, Hult, A, Pelkonen, AS et al.. Expiratory variability index is associated with asthma risk, wheeze and lung function in infants with recurrent respiratory symptoms. ERJ Open Res. 2020;6 (4):. doi: 10.1183/23120541.00167-2020. PubMed PMID:33123560 PubMed Central PMC7569165.
  2. Seppä, VP, Paassilta, M, Kivistö, J, Hult, A, Viik, J, Gracia-Tabuenca, J et al.. Reduced expiratory variability index (EVI) is associated with controller medication withdrawal and symptoms in wheezy children aged 1-5 years. Pediatr Allergy Immunol. 2020;31 (5):489-495. doi: 10.1111/pai.13234. PubMed PMID:32068911 PubMed Central PMC7497189.
  3. Joutsen, A, Hautalahti, J, Jaatinen, E, Goebeler, S, Paldanius, A, Viik, J et al.. A device for measuring sternal bone connectivity using vibration analysis techniques. Proc Inst Mech Eng H. 2020;234 (1):81-90. doi: 10.1177/0954411919884802. PubMed PMID:31856673 .
  4. Milagro, J, Gracia-Tabuenca, J, Seppa, VP, Karjalainen, J, Paassilta, M, Orini, M et al.. Noninvasive Cardiorespiratory Signals Analysis for Asthma Evolution Monitoring in Preschool Children. IEEE Trans Biomed Eng. 2020;67 (7):1863-1871. doi: 10.1109/TBME.2019.2949873. PubMed PMID:31670660 .
  5. Gracia-Tabuenca, J, Seppä, VP, Jauhiainen, M, Paassilta, M, Viik, J, Karjalainen, J et al.. Tidal breathing flow profiles during sleep in wheezing children measured by impedance pneumography. Respir Physiol Neurobiol. 2020;271 :103312. doi: 10.1016/j.resp.2019.103312. PubMed PMID:31585171 .

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2019
  1. Joutsen, A, Hautalahti, J, Jaatinen, E, Goebeler, S, Paldanius, A, Viik, J et al.. A device for measuring sternal bone connectivity using vibration analysis techniques. Proc Inst Mech Eng H. 2020;234 (1):81-90. doi: 10.1177/0954411919884802. PubMed PMID:31856673 .
  2. Milagro, J, Gracia-Tabuenca, J, Seppa, VP, Karjalainen, J, Paassilta, M, Orini, M et al.. Noninvasive Cardiorespiratory Signals Analysis for Asthma Evolution Monitoring in Preschool Children. IEEE Trans Biomed Eng. 2020;67 (7):1863-1871. doi: 10.1109/TBME.2019.2949873. PubMed PMID:31670660 .
  3. Sipilä, K, Tikkakoski, A, Alanko, S, Haarala, A, Hernesniemi, J, Lyytikäinen, LP et al.. Combination of low blood pressure response, low exercise capacity and slow heart rate recovery during an exercise test significantly increases mortality risk. Ann Med. ;51 (7-8):390-396. doi: 10.1080/07853890.2019.1684550. PubMed PMID:31638839 .
  4. Gracia-Tabuenca, J, Seppä, VP, Jauhiainen, M, Paassilta, M, Viik, J, Karjalainen, J et al.. Tidal breathing flow profiles during sleep in wheezing children measured by impedance pneumography. Respir Physiol Neurobiol. 2020;271 :103312. doi: 10.1016/j.resp.2019.103312. PubMed PMID:31585171 .
  5. Seppä, VP, Hult, A, Gracia-Tabuenca, J, Paassilta, M, Viik, J, Plavec, D et al.. Airway obstruction is associated with reduced variability in specific parts of the tidal breathing flow-volume curve in young children. ERJ Open Res. 2019;5 (2):. doi: 10.1183/23120541.00028-2019. PubMed PMID:31218218 PubMed Central PMC6571449.
  6. Kekonen, A, Bergelin, M, Johansson, M, Kumar Joon, N, Bobacka, J, Viik, J et al.. Bioimpedance Sensor Array for Long-Term Monitoring of Wound Healing from Beneath the Primary Dressings and Controlled Formation of H2O2 Using Low-Intensity Direct Current. Sensors (Basel). 2019;19 (11):. doi: 10.3390/s19112505. PubMed PMID:31159298 PubMed Central PMC6603574.
  7. Gracia-Tabuenca, J, Seppä, VP, Jauhiainen, M, Kotaniemi-Syrjänen, A, Malmström, K, Pelkonen, A et al.. Tidal breathing flow volume profiles during sleep in wheezing infants measured by impedance pneumography. J Appl Physiol (1985). 2019;126 (5):1409-1418. doi: 10.1152/japplphysiol.01007.2018. PubMed PMID:30763165 .
  8. Salokari, E, Laukkanen, JA, Lehtimaki, T, Kurl, S, Kunutsor, S, Zaccardi, F et al.. The Duke treadmill score with bicycle ergometer: Exercise capacity is the most important predictor of cardiovascular mortality. Eur J Prev Cardiol. 2019;26 (2):199-207. doi: 10.1177/2047487318804618. PubMed PMID:30354741 PubMed Central PMC6330693.
  9. Kangas, P, Tikkakoski, A, Uitto, M, Viik, J, Bouquin, H, Niemelä, O et al.. Metabolic syndrome is associated with decreased heart rate variability in a sex-dependent manner: a comparison between 252 men and 249 women. Clin Physiol Funct Imaging. 2019;39 (2):160-167. doi: 10.1111/cpf.12551. PubMed PMID:30307694 .

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2018
  1. Salokari, E, Laukkanen, JA, Lehtimaki, T, Kurl, S, Kunutsor, S, Zaccardi, F et al.. The Duke treadmill score with bicycle ergometer: Exercise capacity is the most important predictor of cardiovascular mortality. Eur J Prev Cardiol. 2019;26 (2):199-207. doi: 10.1177/2047487318804618. PubMed PMID:30354741 PubMed Central PMC6330693.
  2. Kangas, P, Tikkakoski, A, Uitto, M, Viik, J, Bouquin, H, Niemelä, O et al.. Metabolic syndrome is associated with decreased heart rate variability in a sex-dependent manner: a comparison between 252 men and 249 women. Clin Physiol Funct Imaging. 2019;39 (2):160-167. doi: 10.1111/cpf.12551. PubMed PMID:30307694 .
  3. Milagro, J, Gil, E, Lazaro, J, Seppa, VP, Malmberg, LP, Pelkonen, AS et al.. Nocturnal Heart Rate Variability Spectrum Characterization in Preschool Children With Asthmatic Symptoms. IEEE J Biomed Health Inform. 2018;22 (5):1332-1340. doi: 10.1109/JBHI.2017.2775059. PubMed PMID:29990113 .
  4. Perez-Macias, JM, Tenhunen, M, Varri, A, Himanen, SL, Viik, J, Perez-Macias, JM et al.. Detection of Snores Using Source Separation on an Emfit Signal. IEEE J Biomed Health Inform. 2018;22 (4):1157-1167. doi: 10.1109/JBHI.2017.2757530. PubMed PMID:28961132 .

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