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Radiology

Publications

2025

  1. Laine, S, Sjöros, T, Garthwaite, T, Honka, MJ, Löyttyniemi, E, Norha, J et al.. Effects of reducing sedentary behavior on liver insulin sensitivity, liver fat content, and liver enzyme levels: A six-month randomized controlled trial. Am J Physiol Endocrinol Metab. 2025; :. doi: 10.1152/ajpendo.00446.2024. PubMed PMID:40244864 .
  2. Vierula, JP, Merisaari, H, Heikkinen, J, Happonen, T, Sirén, A, Velhonoja, J et al.. MRI-based risk factors for intensive care unit admissions in acute neck infections. Eur J Radiol Open. 2025;14 :100648. doi: 10.1016/j.ejro.2025.100648. PubMed PMID:40236980 PubMed Central PMC11999491.
  3. Putkinen, V, Seppälä, K, Harju, H, Hirvonen, J, Karlsson, HK, Nummenmaa, L et al.. Pleasurable music activates cerebral µ-opioid receptors: a combined PET-fMRI study. Eur J Nucl Med Mol Imaging. 2025; :. doi: 10.1007/s00259-025-07232-z. PubMed PMID:40183950 .
  4. Sahin, O, Kamel, S, Wahid, KA, Dede, C, Taku, N, He, R et al.. International multispecialty expert physician preoperative identification of extranodal extension in patients with oropharyngeal cancer using computed tomography: Prospective blinded human inter-observer performance evaluation. Cancer. 2025;131 (7):e35815. doi: 10.1002/cncr.35815. PubMed PMID:40159431 .
  5. Huhtanen, HJ, Nyman, MJ, Karlsson, A, Hirvonen, J. Machine Learning and Deep Learning Models for Automated Protocoling of Emergency Brain MRI Using Text from Clinical Referrals. Radiol Artif Intell. 2025;7 (3):e230620. doi: 10.1148/ryai.230620. PubMed PMID:39969276 .
  6. Järvinen, L, Santavirta, S, Putkinen, V, Karlsson, HK, Seppälä, K, Sun, L et al.. Reward responses to vicarious feeding depend on body mass index. Cogn Affect Behav Neurosci. 2025; :. doi: 10.3758/s13415-025-01265-5. PubMed PMID:39966303 .
  7. Connor, S, Christoforou, A, Touska, P, Robinson, S, Fischbein, NJ, de Graaf, P et al.. An international survey of diffusion and perfusion magnetic resonance imaging implementation in the head and neck. Eur Radiol. 2025; :. doi: 10.1007/s00330-025-11370-1. PubMed PMID:39904786 .
  8. Lääveri, M, Heikkinen, J, Happonen, T, Sirén, A, Nurminen, J, Vierula, JP et al.. Odontogenic neck abscesses caused by Streptococcus anginosus group bacteria: emergency MRI findings. Oral Surg Oral Med Oral Pathol Oral Radiol. 2025;139 (5):594-599. doi: 10.1016/j.oooo.2024.12.017. PubMed PMID:39904716 .
  9. Pak, K, Tuisku, J, Karlsson, HK, Hirvonen, J, Rebelos, E, Pekkarinen, L et al.. Anorexia nervosa is associated with higher brain mu-opioid receptor availability. Mol Psychiatry. 2025; :. doi: 10.1038/s41380-025-02888-3. PubMed PMID:39800744 .
  10. Ajalin, R, Al-Abdulrasul, H, Tuisku, JM, Hirvonen, J, Lahdenpohja, S, Rinne, JO et al.. Impaired Gait, Postural Instability, and Rigidity in Relation to CB1 Receptor Availability in Parkinson’s Disease. Mov Disord. 2025;40 (1):163-167. doi: 10.1002/mds.30042. PubMed PMID:39435606 PubMed Central PMC11752992.

Search PubMed

2024

  1. Lääveri, M, Heikkinen, J, Happonen, T, Sirén, A, Nurminen, J, Vierula, JP et al.. Odontogenic neck abscesses caused by Streptococcus anginosus group bacteria: emergency MRI findings. Oral Surg Oral Med Oral Pathol Oral Radiol. 2024; :. doi: 10.1016/j.oooo.2024.12.017. PubMed PMID:39904716 .
  2. Huhtanen, JT, Nyman, M, Sequeiros, RB, Koskinen, SK, Pudas, TK, Kajander, S et al.. Correction: Huhtanen et al. Discrepancies between Radiology Specialists and Residents in Fracture Detection from Musculoskeletal Radiographs. Diagnostics 2023, , 3207. Diagnostics (Basel). 2024;15 (1):. doi: 10.3390/diagnostics15010003. PubMed PMID:39795645 PubMed Central PMC11719973.
  3. Abdullaeva, U, Pape, B, Hirvonen, J. Diagnostic Accuracy of MRI for Orbital and Intracranial Invasion of Sinonasal Malignancies: A Systematic Review and Meta-Analysis. J Clin Med. 2024;13 (24):. doi: 10.3390/jcm13247556. PubMed PMID:39768479 PubMed Central PMC11728326.
  4. Mickelsson, N, Hirvonen, J, Martikainen, MH. Clinical features and treatment of stroke-like episodes in mitochondrial disease: a cohort-based study. J Neurol. 2024;272 (1):47. doi: 10.1007/s00415-024-12745-y. PubMed PMID:39666093 PubMed Central PMC11638336.
  5. Sirén, A, Nyman, M, Syvänen, J, Mattila, K, Hirvonen, J. Imaging Outcomes of MRI After CT in Pediatric Spinal Trauma: A Single-center Experience. J Pediatr Orthop. ;44 (10):e887-e893. doi: 10.1097/BPO.0000000000002765. PubMed PMID:39466292 PubMed Central PMC11458097.
  6. Chen, J, Putkinen, V, Seppälä, K, Hirvonen, J, Ioumpa, K, Gazzola, V et al.. Endogenous opioid receptor system mediates costly altruism in the human brain. Commun Biol. 2024;7 (1):1401. doi: 10.1038/s42003-024-07084-7. PubMed PMID:39462097 PubMed Central PMC11513155.
  7. Ajalin, R, Al-Abdulrasul, H, Tuisku, JM, Hirvonen, J, Lahdenpohja, S, Rinne, JO et al.. Impaired Gait, Postural Instability, and Rigidity in Relation to CB1 Receptor Availability in Parkinson’s Disease. Mov Disord. 2025;40 (1):163-167. doi: 10.1002/mds.30042. PubMed PMID:39435606 PubMed Central PMC11752992.
  8. Rantasalo, V, Gunn, J, Pan, E, Kiviniemi, T, Hirvonen, J, Rahi, M et al.. In Reply to the Letter to the Editor Regarding “Positive Correlation Between Thoracic Aortic Diameter and Intracranial Aneurysm Size-An Observational Cohort Study”. World Neurosurg. 2024;190 :546-547. doi: 10.1016/j.wneu.2024.07.106. PubMed PMID:39425289 .
  9. Kokkonen, A, Corp, DT, Aaltonen, J, Hirvonen, J, Kirjavainen, AK, Rajander, J et al.. Brain metabolic response to repetitive transcranial magnetic stimulation to lesion network in cervical dystonia. Brain Stimul. 2024;17 (6):1171-1177. doi: 10.1016/j.brs.2024.10.004. PubMed PMID:39396800 .
  10. Norha, J, Sjöros, T, Garthwaite, T, Laine, S, Verho, T, Saunavaara, V et al.. Effects of reducing sedentary behaviour on back pain, paraspinal muscle insulin sensitivity and muscle fat fraction and their associations: a secondary analysis of a 6-month randomised controlled trial. BMJ Open. 2024;14 (9):e084305. doi: 10.1136/bmjopen-2024-084305. PubMed PMID:39343453 PubMed Central PMC11440184.
  11. Sirén, A, Turkia, E, Nyman, M, Hirvonen, J. Accuracy of Intra-Axial Brain Tumor Characterization in the Emergency MRI Reports: A Retrospective Human Performance Benchmarking Pilot Study. Diagnostics (Basel). 2024;14 (16):. doi: 10.3390/diagnostics14161791. PubMed PMID:39202279 PubMed Central PMC11353410.
  12. Kolasa, M, Arponen, O, Kaartinen, I, Saarinen, E, Solje, E, Hirvonen, J et al.. Correlation of cerebral small vessel disease burden with outcome after lower extremity amputation. J Diabetes Complications. 2024;38 (9):108829. doi: 10.1016/j.jdiacomp.2024.108829. PubMed PMID:39059188 .
  13. Laine, S, Sjöros, T, Garthwaite, T, Honka, MJ, Löyttyniemi, E, Eskola, O et al.. Daily standing time, dietary fiber, and intake of unsaturated fatty acids are beneficially associated with hepatic insulin sensitivity in adults with metabolic syndrome. Front Endocrinol (Lausanne). 2024;15 :1272886. doi: 10.3389/fendo.2024.1272886. PubMed PMID:38989003 PubMed Central PMC11233550.
  14. Kuuskoski, J, Vanhatalo, J, Hirvonen, J, Rekola, J, Aaltonen, LM, Järvenpää, P et al.. Inter-rater reliability and clinical relevance of subjective and objective interpretation of videofluoroscopy findings. Laryngoscope Investig Otolaryngol. 2024;9 (4):e1298. doi: 10.1002/lio2.1298. PubMed PMID:38974605 PubMed Central PMC11222653.
  15. Lukkarinen, L, Tuisku, J, Sun, L, Helin, S, Karlsson, HK, Venetjoki, N et al.. Aberrant type 2 dopamine receptor availability in violent offenders with psychopathy. Neuroimage. 2024;297 :120724. doi: 10.1016/j.neuroimage.2024.120724. PubMed PMID:38971486 .
  16. Wintermark, M, Allen, JW, Anzai, Y, Das, T, Flanders, AE, Galanaud, D et al.. Standardized reporting for Head CT Scans in patients suspected of traumatic brain injury (TBI): An international expert endeavor. Neuroradiology. 2024;66 (9):1513-1526. doi: 10.1007/s00234-024-03410-2. PubMed PMID:38963424 .
  17. Laukka, D, Kangas, E, Kuusela, A, Hirvonen, J, Rissanen, T, Rahi, M et al.. In Reply: Low and Borderline Ankle-Brachial Index Is Associated With Intracranial Aneurysms: A Retrospective Cohort Study. Neurosurgery. 2024;95 (2):e47-e48. doi: 10.1227/neu.0000000000003059. PubMed PMID:38869280PubMed Central PMC11219158.
  18. Happonen, T, Nyman, M, Ylikotila, P, Mattila, K, Hirvonen, J. Imaging Outcomes of Emergency MR Imaging in Dizziness and Vertigo: A Retrospective Cohort Study. AJNR Am J Neuroradiol. 2024;45 (6):819-825. doi: 10.3174/ajnr.A8202. PubMed PMID:38604735 PubMed Central PMC11288592.
  19. Rantasalo, V, Gunn, J, Pan, E, Kiviniemi, T, Hirvonen, J, Rahi, M et al.. Positive Correlation Between Thoracic Aortic Diameter and Intracranial Aneurysm Size-An Observational Cohort Study. World Neurosurg. 2024;184 :e633-e646. doi: 10.1016/j.wneu.2024.02.007. PubMed PMID:38342167 .
  20. Sirén, A, Nyman, M, Syvänen, J, Mattila, K, Hirvonen, J. Utility of brain imaging in pediatric patients with a suspected accidental spinal injury but no brain injury-related symptoms. Childs Nerv Syst. 2024;40 (5):1435-1441. doi: 10.1007/s00381-024-06298-8. PubMed PMID:38279986 PubMed Central PMC11026267.
  21. Laukka, D, Kangas, E, Kuusela, A, Hirvonen, J, Rissanen, T, Rahi, M et al.. Low and Borderline Ankle-Brachial Index Is Associated With Intracranial Aneurysms: A Retrospective Cohort Study. Neurosurgery. 2024;94 (6):1282-90. doi: 10.1227/neu.0000000000002837. PubMed PMID:38270446 PubMed Central PMC11073771.
  22. Sirén, A, Syvänen, J, Nyman, M, Mattila, K, Hirvonen, J. Outcomes of Follow-up Imaging After Pediatric Spinal Trauma Confirmed With Magnetic Resonance Imaging. J Pediatr Orthop. 2024;44 (4):e329-e334. doi: 10.1097/BPO.0000000000002615. PubMed PMID:38223936 PubMed Central PMC10913857.
  23. Abdullaeva, U, Pape, B, Hirvonen, J. Diagnostic Accuracy of MRI in Detecting the Perineural Spread of Head and Neck Tumors: A Systematic Review and Meta-Analysis. Diagnostics (Basel). 2024;14 (1):. doi: 10.3390/diagnostics14010113. PubMed PMID:38201423 PubMed Central PMC10795679.
  24. Laukka, D, Kivelev, J, Rahi, M, Vahlberg, T, Paturi, J, Rinne, J et al.. Detection Rates and Trends of Asymptomatic Unruptured Intracranial Aneurysms From 2005 to 2019. Neurosurgery. 2024;94 (2):297-306. doi: 10.1227/neu.0000000000002664. PubMed PMID:37695560 PubMed Central PMC10766300.
  25. Multidisciplinary Oropharyngeal Cancer Extra-Nodal Extension (OPC ENE) Assessment Working Group, Sahin, O, Kamel, S, Wahid, KA, Dede, C, Taku, N et al.. International Multi-Specialty Expert Physician Preoperative Identification of Extranodal Extension n Oropharyngeal Cancer Patients using Computed Tomography: Prospective Blinded Human Inter-Observer Performance Evaluation. medRxiv. 2024; :. doi: 10.1101/2023.02.25.23286432. PubMed PMID:36865096 PubMed Central PMC9980252.

Search PubMed

2023

  1. Huhtanen, JT, Nyman, M, Sequeiros, RB, Koskinen, SK, Pudas, TK, Kajander, S et al.. Discrepancies between Radiology Specialists and Residents in Fracture Detection from Musculoskeletal Radiographs. Diagnostics (Basel). 2023;13 (20):. doi: 10.3390/diagnostics13203207. PubMed PMID:37892028 PubMed Central PMC10605667.
  2. Vierula, JP, Nurminen, J, Jussila, V, Nyman, M, Heikkinen, J, Pape, B et al.. Diagnostic performance of short noncontrast biparametric 3-T MRI for tonsillar infections: comparison with a full protocol including contrast-enhanced sequences. Eur Radiol Exp. 2023;7 (1):65. doi: 10.1186/s41747-023-00379-0. PubMed PMID:37872406 PubMed Central PMC10593634.
  3. Laukka, D, Kivelev, J, Rahi, M, Vahlberg, T, Paturi, J, Rinne, J et al.. Detection Rates and Trends of Asymptomatic Unruptured Intracranial Aneurysms From 2005 to 2019. Neurosurgery. 2024;94 (2):297-306. doi: 10.1227/neu.0000000000002664. PubMed PMID:37695560 PubMed Central PMC10766300.
  4. European Society of Radiology (ESR). Resident education in radiology in Europe including entrustable professional activities: results of an ESR survey. Insights Imaging. 2023;14 (1):139. doi: 10.1186/s13244-023-01489-4. PubMed PMID:37606861 PubMed Central PMC10444922.
  5. Hossain, I, Mohammadian, M, Maanpää, HR, Takala, RSK, Tenovuo, O, van Gils, M et al.. Plasma neurofilament light admission levels and development of axonal pathology in mild traumatic brain injury. BMC Neurol. 2023;23 (1):304. doi: 10.1186/s12883-023-03284-6. PubMed PMID:37582732 PubMed Central PMC10426141.
  6. Silvoniemi, A, Laine, J, Aro, K, Nissi, L, Bäck, L, Schildt, J et al.. Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma: Association with Metabolic Tumor Burden Determined with FDG-PET/CT. Cancers (Basel). 2023;15 (15):. doi: 10.3390/cancers15153970. PubMed PMID:37568786 PubMed Central PMC10416934.
  7. Sirén, A, Nyman, M, Syvänen, J, Mattila, K, Hirvonen, J. Clinical outcome following magnetic resonance imaging as first-line imaging in low-impact pediatric spine trauma: a single-center retrospective observational study. Pediatr Radiol. 2023;53 (11):2269-2280. doi: 10.1007/s00247-023-05721-7. PubMed PMID:37518674 PubMed Central PMC10562339.
  8. Sirén, A, Nyman, M, Syvänen, J, Mattila, K, Hirvonen, J. Emergency MRI in Spine Trauma of Children and Adolescents-A Pictorial Review. Children (Basel). 2023;10 (7):. doi: 10.3390/children10071094. PubMed PMID:37508591 PubMed Central PMC10378627.
  9. Jern, P, Chen, J, Tuisku, J, Saanijoki, T, Hirvonen, J, Lukkarinen, L et al.. Endogenous Opioid Release After Orgasm in Man: A Combined PET/Functional MRI Study. J Nucl Med. 2023;64 (8):1310-1313. doi: 10.2967/jnumed.123.265512. PubMed PMID:37442599 PubMed Central PMC10394307.
  10. Nurminen, J, Heikkinen, J, Happonen, T, Nyman, M, Sirén, A, Vierula, JP et al.. Pictorial Review of MRI Findings in Acute Neck Infections in Children. Children (Basel). 2023;10 (6):. doi: 10.3390/children10060967. PubMed PMID:37371199 PubMed Central PMC10296820.
  11. Happonen, T, Nyman, M, Ylikotila, P, Kytö, V, Laukka, D, Mattila, K et al.. Imaging Outcomes of Emergency MRI in Patients with Suspected Cerebral Venous Sinus Thrombosis: A Retrospective Cohort Study. Diagnostics (Basel). 2023;13 (12):. doi: 10.3390/diagnostics13122052. PubMed PMID:37370947 PubMed Central PMC10297083.
  12. Kuusisto, N, Hirvonen, J, Suominen, A, Syrjänen, S, Huumonen, S, Vallittu, P et al.. Retrospective Analysis of Artifacts in Cone Beam Computed Tomography Images Used to Diagnose Chronic Rhinosinusitis. Diagnostics (Basel). 2023;13 (9):. doi: 10.3390/diagnostics13091511. PubMed PMID:37174903 PubMed Central PMC10177128.
  13. Nummenmaa, L, Malèn, T, Nazari-Farsani, S, Seppälä, K, Sun, L, Santavirta, S et al.. Decoding brain basis of laughter and crying in natural scenes. Neuroimage. 2023;273 :120082. doi: 10.1016/j.neuroimage.2023.120082. PubMed PMID:37030414 .
  14. Santavirta, S, Karjalainen, T, Nazari-Farsani, S, Hudson, M, Putkinen, V, Seppälä, K et al.. Functional organization of social perception networks in the human brain. Neuroimage. 2023;272 :120025. doi: 10.1016/j.neuroimage.2023.120025. PubMed PMID:36958619 PubMed Central PMC10112277.
  15. Hudson, M, Santavirta, S, Putkinen, V, Seppälä, K, Sun, L, Karjalainen, T et al.. Neural responses to biological motion distinguish autistic and schizotypal traits. Soc Cogn Affect Neurosci. 2023;18 (1):. doi: 10.1093/scan/nsad011. PubMed PMID:36847146 PubMed Central PMC10032360.
  16. Putkinen, V, Nazari-Farsani, S, Karjalainen, T, Santavirta, S, Hudson, M, Seppälä, K et al.. Pattern recognition reveals sex-dependent neural substrates of sexual perception. Hum Brain Mapp. 2023;44 (6):2543-2556. doi: 10.1002/hbm.26229. PubMed PMID:36773282 PubMed Central PMC10028630.
  17. Mansikka, I, Kinnunen, I, Hirvonen, J, Vainio, P, Velhonoja, J. Tumor-to-tumor metastasis to Warthin tumor presenting as an initial sign of breast carcinoma: A case report. Clin Case Rep. 2023;11 (1):e6817. doi: 10.1002/ccr3.6817. PubMed PMID:36619482 PubMed Central PMC9817488.
  18. Hirvonen, J, Heikkinen, J, Nyman, M, Happonen, T, Velhonoja, J, Irjala, H et al.. MRI of acute neck infections: evidence summary and pictorial review. Insights Imaging. 2023;14 (1):5. doi: 10.1186/s13244-022-01347-9. PubMed PMID:36617619 PubMed Central PMC9826778.
  19. Sirén, A, Mattila, K, Hirvonen, J. The natural course of bridging osteophyte formation on MRI-A pictorial illustration. Radiol Case Rep. 2023;18 (1):218-221. doi: 10.1016/j.radcr.2022.10.011. PubMed PMID:36340242 PubMed Central PMC9633554.
  20. Happonen, T, Nyman, M, Ylikotila, P, Merisaari, H, Mattila, K, Hirvonen, J et al.. Diagnostic yield of emergency MRI in non-traumatic headache. Neuroradiology. 2023;65 (1):89-96. doi: 10.1007/s00234-022-03044-2. PubMed PMID:36029327 PubMed Central PMC9816281.
  21. Heikkinen, J, Jokihaka, V, Nurminen, J, Jussila, V, Velhonoja, J, Irjala, H et al.. MRI of odontogenic maxillofacial infections: diagnostic accuracy and reliability. Oral Radiol. 2023;39 (2):364-371. doi: 10.1007/s11282-022-00646-7. PubMed PMID:35943697 PubMed Central PMC10017569.

Search PubMed

2022

  1. Sirén, A, Mattila, K, Hirvonen, J. The natural course of bridging osteophyte formation on MRI-A pictorial illustration. Radiol Case Rep. 2023;18 (1):218-221. doi: 10.1016/j.radcr.2022.10.011. PubMed PMID:36340242 PubMed Central PMC9633554.
  2. Laukka, D, Parkkola, R, Hirvonen, J, Ylikotila, P, Vahlberg, T, Salo, E et al.. Brain white matter hyperintensities in Kawasaki disease: A case-control study. Front Neurosci. 2022;16 :995480. doi: 10.3389/fnins.2022.995480. PubMed PMID:36330348 PubMed Central PMC9623056.
  3. Hagelberg, J, Pape, B, Heikkinen, J, Nurminen, J, Mattila, K, Hirvonen, J et al.. Diagnostic accuracy of contrast-enhanced CT for neck abscesses: A systematic review and meta-analysis of positive predictive value. PLoS One. 2022;17 (10):e0276544. doi: 10.1371/journal.pone.0276544. PubMed PMID:36288374 PubMed Central PMC9604924.
  4. Sun, L, Lukkarinen, L, Putkinen, V, Karlsson, HK, Hirvonen, J, Tiihonen, J et al.. Mu-opioid receptor system modulates responses to vocal bonding and distress signals in humans. Philos Trans R Soc Lond B Biol Sci. 2022;377 (1863):20210181. doi: 10.1098/rstb.2021.0181. PubMed PMID:36126675 PubMed Central PMC9489292.
  5. Happonen, T, Nyman, M, Ylikotila, P, Merisaari, H, Mattila, K, Hirvonen, J et al.. Diagnostic yield of emergency MRI in non-traumatic headache. Neuroradiology. 2023;65 (1):89-96. doi: 10.1007/s00234-022-03044-2. PubMed PMID:36029327 PubMed Central PMC9816281.
  6. Heikkinen, J, Jokihaka, V, Nurminen, J, Jussila, V, Velhonoja, J, Irjala, H et al.. MRI of odontogenic maxillofacial infections: diagnostic accuracy and reliability. Oral Radiol. 2023;39 (2):364-371. doi: 10.1007/s11282-022-00646-7. PubMed PMID:35943697 PubMed Central PMC10017569.
  7. Noppari, T, Sun, L, Lukkarinen, L, Putkinen, V, Tani, P, Lindberg, N et al.. Brain structural alterations in autism and criminal psychopathy. Neuroimage Clin. 2022;35 :103116. doi: 10.1016/j.nicl.2022.103116. PubMed PMID:35872437 PubMed Central PMC9421457.
  8. Huhtanen, JT, Nyman, M, Doncenco, D, Hamedian, M, Kawalya, D, Salminen, L et al.. Deep learning accurately classifies elbow joint effusion in adult and pediatric radiographs. Sci Rep. 2022;12 (1):11803. doi: 10.1038/s41598-022-16154-x. PubMed PMID:35821056 PubMed Central PMC9276721.
  9. Dahl, J, Tenovuo, O, Posti, JP, Hirvonen, J, Katila, AJ, Frantzén, J et al.. Cerebral Microbleeds and Structural White Matter Integrity in Patients With Traumatic Brain Injury-A Diffusion Tensor Imaging Study. Front Neurol. 2022;13 :888815. doi: 10.3389/fneur.2022.888815. PubMed PMID:35711272 PubMed Central PMC9194845.
  10. Ajalin, RM, Al-Abdulrasul, H, Tuisku, JM, Hirvonen, JES, Vahlberg, T, Lahdenpohja, S et al.. Cannabinoid Receptor Type 1 in Parkinson’s Disease: A Positron Emission Tomography Study with [ F]FMPEP-d. Mov Disord. 2022;37 (8):1673-1682. doi: 10.1002/mds.29117. PubMed PMID:35674270 PubMed Central PMC9544132.
  11. Sun, L, Lukkarinen, L, Noppari, T, Nazari-Farsani, S, Putkinen, V, Seppälä, K et al.. Aberrant motor contagion of emotions in psychopathy and high-functioning autism. Cereb Cortex. 2022;33 (2):374-384. doi: 10.1093/cercor/bhac072. PubMed PMID:35332920 PubMed Central PMC9837606.
  12. Huhtanen, H, Nyman, M, Mohsen, T, Virkki, A, Karlsson, A, Hirvonen, J et al.. Automated detection of pulmonary embolism from CT-angiograms using deep learning. BMC Med Imaging. 2022;22 (1):43. doi: 10.1186/s12880-022-00763-z. PubMed PMID:35282821 PubMed Central PMC8919639.
  13. Saanijoki, T, Kantonen, T, Pekkarinen, L, Kalliokoski, K, Hirvonen, J, Malén, T et al.. Aerobic Fitness Is Associated with Cerebral μ-Opioid Receptor Activation in Healthy Humans. Med Sci Sports Exerc. 2022;54 (7):1076-1084. doi: 10.1249/MSS.0000000000002895. PubMed PMID:35195103 .
  14. Nurminen, J, Heikkinen, J, Happonen, T, Velhonoja, J, Irjala, H, Soukka, T et al.. Magnetic resonance imaging findings in pediatric neck infections-a comparison with adult patients. Pediatr Radiol. 2022;52 (6):1158-1166. doi: 10.1007/s00247-021-05275-6. PubMed PMID:35184213 PubMed Central PMC9107440.
  15. Roine, T, Mohammadian, M, Hirvonen, J, Kurki, T, Posti, JP, Takala, RSK et al.. Structural Brain Connectivity Correlates with Outcome in Mild Traumatic Brain Injury. J Neurotrauma. 2022;39 (5-6):336-347. doi: 10.1089/neu.2021.0093. PubMed PMID:35018829 .
  16. Kantonen, T, Pekkarinen, L, Karjalainen, T, Bucci, M, Kalliokoski, K, Haaparanta-Solin, M et al.. Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB receptor availability. Int J Obes (Lond). 2022;46 (2):400-407. doi: 10.1038/s41366-021-00996-y. PubMed PMID:34728775 PubMed Central PMC8794779.
  17. Heikkinen, J, Nurminen, J, Velhonoja, J, Irjala, H, Happonen, T, Soukka, T et al.. Clinical and prognostic significance of emergency MRI findings in neck infections. Eur Radiol. 2022;32 (2):1078-1086. doi: 10.1007/s00330-021-08200-5. PubMed PMID:34331114 PubMed Central PMC8794929.

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2021

  1. Kantonen, T, Pekkarinen, L, Karjalainen, T, Bucci, M, Kalliokoski, K, Haaparanta-Solin, M et al.. Obesity risk is associated with altered cerebral glucose metabolism and decreased μ-opioid and CB1 receptor availability. Int J Obes (Lond). 2022;46 (2):400-407. doi: 10.1038/s41366-021-00996-y. PubMed PMID:34728775 PubMed Central PMC8794779.
  2. Rantasalo, V, Gunn, J, Kiviniemi, T, Hirvonen, J, Saarenpää, I, Kivelev, J et al.. Intracranial aneurysm is predicted by abdominal aortic calcification index: A retrospective case-control study. Atherosclerosis. 2021;334 :30-38. doi: 10.1016/j.atherosclerosis.2021.08.027. PubMed PMID:34461392 .
  3. Kantonen, T, Karjalainen, T, Pekkarinen, L, Isojärvi, J, Kalliokoski, K, Kaasinen, V et al.. Cerebral μ-opioid and CB1 receptor systems have distinct roles in human feeding behavior. Transl Psychiatry. 2021;11 (1):442. doi: 10.1038/s41398-021-01559-5. PubMed PMID:34453034 PubMed Central PMC8397789.
  4. Heikkinen, J, Nurminen, J, Velhonoja, J, Irjala, H, Happonen, T, Soukka, T et al.. Clinical and prognostic significance of emergency MRI findings in neck infections. Eur Radiol. 2022;32 (2):1078-1086. doi: 10.1007/s00330-021-08200-5. PubMed PMID:34331114 PubMed Central PMC8794929.
  5. Panula, E, Hirvonen, J, Vahlberg, T, Schrey, A, Irjala, H. Practical aspects of sentinel node biopsy in oral cavity cancer: all nodes that emit a signal are important. Acta Otolaryngol. 2021;141 (8):820-824. doi: 10.1080/00016489.2021.1945681. PubMed PMID:34275432 .
  6. Nummenmaa, L, Lukkarinen, L, Sun, L, Putkinen, V, Seppälä, K, Karjalainen, T et al.. Brain Basis of Psychopathy in Criminal Offenders and General Population. Cereb Cortex. 2021;31 (9):4104-4114. doi: 10.1093/cercor/bhab072. PubMed PMID:33834203 PubMed Central PMC8328218.
  7. Velhonoja, J, Lääveri, M, Soukka, T, Hirvonen, J, Kinnunen, I, Irjala, H et al.. Early surgical intervention enhances recovery of severe pediatric deep neck infection patients. Int J Pediatr Otorhinolaryngol. 2021;144 :110694. doi: 10.1016/j.ijporl.2021.110694. PubMed PMID:33799100 .
  8. Rebelos, E, Bucci, M, Karjalainen, T, Oikonen, V, Bertoldo, A, Hannukainen, JC et al.. Insulin Resistance Is Associated With Enhanced Brain Glucose Uptake During Euglycemic Hyperinsulinemia: A Large-Scale PET Cohort. Diabetes Care. 2021;44 (3):788-794. doi: 10.2337/dc20-1549. PubMed PMID:33446523 PubMed Central PMC7896252.
  9. Putkinen, V, Nazari-Farsani, S, Seppälä, K, Karjalainen, T, Sun, L, Karlsson, HK et al.. Decoding Music-Evoked Emotions in the Auditory and Motor Cortex. Cereb Cortex. 2021;31 (5):2549-2560. doi: 10.1093/cercor/bhaa373. PubMed PMID:33367590 .
  10. Sun, L, Tang, J, Liljenbäck, H, Honkaniemi, A, Virta, J, Isojärvi, J et al.. Seasonal Variation in the Brain μ-Opioid Receptor Availability. J Neurosci. 2021;41 (6):1265-1273. doi: 10.1523/JNEUROSCI.2380-20.2020. PubMed PMID:33361461 PubMed Central PMC7888218.
  11. Nurminen, J, Velhonoja, J, Heikkinen, J, Happonen, T, Nyman, M, Irjala, H et al.. Emergency neck MRI: feasibility and diagnostic accuracy in cases of neck infection. Acta Radiol. 2021;62 (6):735-742. doi: 10.1177/0284185120940242. PubMed PMID:32660316 PubMed Central PMC8167911.

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2020

  1. Sun, L, Tang, J, Liljenbäck, H, Honkaniemi, A, Virta, J, Isojärvi, J et al.. Seasonal Variation in the Brain μ-Opioid Receptor Availability. J Neurosci. 2021;41 (6):1265-1273. doi: 10.1523/JNEUROSCI.2380-20.2020. PubMed PMID:33361461 PubMed Central PMC7888218.
  2. Shetty, HU, Zoghbi, SS, Morse, CL, Kowalski, A, Hirvonen, J, Innis, RB et al.. Development of a non-radiometric method for measuring the arterial input function of a 11C-labeled PET radiotracer. Sci Rep. 2020;10 (1):17350. doi: 10.1038/s41598-020-73646-4. PubMed PMID:33060616 PubMed Central PMC7562706.
  3. Rebelos, E, Mari, A, Bucci, M, Honka, MJ, Hannukainen, JC, Virtanen, KA et al.. Brain substrate metabolism and ß-cell function in humans: A positron emission tomography study. Endocrinol Diabetes Metab. 2020;3 (3):e00136. doi: 10.1002/edm2.136. PubMed PMID:32704559 PubMed Central PMC7375082.
  4. Mohammadian, M, Roine, T, Hirvonen, J, Kurki, T, Posti, JP, Katila, AJ et al.. Alterations in Microstructure and Local Fiber Orientation of White Matter Are Associated with Outcome after Mild Traumatic Brain Injury. J Neurotrauma. 2020;37 (24):2616-2623. doi: 10.1089/neu.2020.7081. PubMed PMID:32689872 .
  5. Nurminen, J, Velhonoja, J, Heikkinen, J, Happonen, T, Nyman, M, Irjala, H et al.. Emergency neck MRI: feasibility and diagnostic accuracy in cases of neck infection. Acta Radiol. 2021;62 (6):735-742. doi: 10.1177/0284185120940242. PubMed PMID:32660316 PubMed Central PMC8167911.
  6. Nummenmaa, L, Karjalainen, T, Isojärvi, J, Kantonen, T, Tuisku, J, Kaasinen, V et al.. Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety. Neuropsychopharmacology. 2020;45 (11):1953-1959. doi: 10.1038/s41386-020-0725-9. PubMed PMID:32473595 PubMed Central PMC7608336.
  7. Kantonen, T, Karjalainen, T, Isojärvi, J, Nuutila, P, Tuisku, J, Rinne, J et al.. Interindividual variability and lateralization of μ-opioid receptors in the human brain. Neuroimage. 2020;217 :116922. doi: 10.1016/j.neuroimage.2020.116922. PubMed PMID:32407992 .
  8. Karjalainen, T, Tuisku, J, Santavirta, S, Kantonen, T, Bucci, M, Tuominen, L et al.. Magia: Robust Automated Image Processing and Kinetic Modeling Toolbox for PET Neuroinformatics. Front Neuroinform. 2020;14 :3. doi: 10.3389/fninf.2020.00003. PubMed PMID:32116627 PubMed Central PMC7012016.
  9. Rebelos, E, Hirvonen, J, Bucci, M, Pekkarinen, L, Nyman, M, Hannukainen, JC et al.. Brain free fatty acid uptake is elevated in morbid obesity, and is irreversible 6 months after bariatric surgery: A positron emission tomography study. Diabetes Obes Metab. 2020;22 (7):1074-1082. doi: 10.1111/dom.13996. PubMed PMID:32052537 PubMed Central PMC7318232.
  10. Hudson, M, Seppälä, K, Putkinen, V, Sun, L, Glerean, E, Karjalainen, T et al.. Dissociable neural systems for unconditioned acute and sustained fear. Neuroimage. 2020;216 :116522. doi: 10.1016/j.neuroimage.2020.116522. PubMed PMID:31926280 .

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2019

  1. Laukka, D, Pan, E, Fordell, T, Alpay, K, Rahi, M, Hirvonen, J et al.. Prevalence of thoracic aortic aneurysms and dilatations in patients with intracranial aneurysms. J Vasc Surg. 2019;70 (6):1801-1808. doi: 10.1016/j.jvs.2019.01.066. PubMed PMID:31327605 .
  2. Johansson, J, Hirvonen, J, Lovró, Z, Ekblad, L, Kaasinen, V, Rajasilta, O et al.. Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects. Neuropsychopharmacology. 2019;44 (9):1667-1673. doi: 10.1038/s41386-019-0368-x. PubMed PMID:30867551 PubMed Central PMC6785104.
  3. Nyman, M, Eskola, O, Kajander, J, Jokinen, R, Penttinen, J, Karjalainen, T et al.. Brain neurokinin-1 receptor availability in never-medicated patients with major depression – A pilot study. J Affect Disord. 2019;242 :188-194. doi: 10.1016/j.jad.2018.08.084. PubMed PMID:30193189 .

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