Publications

2024

  1. Vecchio, F, Carré, A, Korenkov, D, Zhou, Z, Apaolaza, P, Tuomela, S et al.. Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 T cell responses. Sci Adv. 2024;10 (10):eadl1122. doi: 10.1126/sciadv.adl1122. PubMed PMID:38446892 PubMed Central PMC10917340.
  2. de Ruyter, H, Aitokari, L, Lahti, S, Riekki, H, Huhtala, H, Lakka, T et al.. Maternal gestational hypertension, smoking and pre-eclampsia are associated with metabolic dysfunction-associated fatty liver disease in overweight offspring. Acta Obstet Gynecol Scand. 2024; :. doi: 10.1111/aogs.14816. PubMed PMID:38433535 .
  3. Mars, N, Kerminen, S, Tamlander, M, Pirinen, M, Jakkula, E, Aaltonen, K et al.. Comprehensive Inherited Risk Estimation for Risk-Based Breast Cancer Screening in Women. J Clin Oncol. 2024; :JCO2300295. doi: 10.1200/JCO.23.00295. PubMed PMID:38422475 .
  4. Gidado, S, Musa, M, Ba’aba, AI, Francis, MR, Okeke, LA, Bukar, FL et al.. Knowledge, risk perception and uptake of COVID-19 vaccination among internally displaced persons in complex humanitarian emergency setting, Northeast Nigeria. BMC Public Health. 2024;24 (1):634. doi: 10.1186/s12889-024-18164-y. PubMed PMID:38419036 PubMed Central PMC10902942.
  5. Kauppala, A, Heikkilä, P, Palmu, S. An analysis of the diagnoses and costs of pediatric emergency care visits: a single center study. BMC Health Serv Res. 2024;24 (1):251. doi: 10.1186/s12913-024-10746-1. PubMed PMID:38414020 PubMed Central PMC10900614.
  6. Hakola, L, Mramba, LK, Uusitalo, U, Andrén Aronsson, C, Hummel, S, Niinistö, S et al.. Intake of B vitamins and the risk of developing islet autoimmunity and type 1 diabetes in the TEDDY study. Eur J Nutr. 2024; :. doi: 10.1007/s00394-024-03346-6. PubMed PMID:38413484 .
  7. Burns, K, Mullin, BH, Moolhuijsen, LME, Laisk, T, Tyrmi, JS, Cui, J et al.. Body mass index stratified meta-analysis of genome-wide association studies of polycystic ovary syndrome in women of European ancestry. BMC Genomics. 2024;25 (1):208. doi: 10.1186/s12864-024-09990-w. PubMed PMID:38408933 PubMed Central PMC10895801.
  8. Hyöty, H, Kääriäinen, S, Laiho, JE, Comer, GM, Tian, W, Härkönen, T et al.. Safety, tolerability and immunogenicity of PRV-101, a multivalent vaccine targeting coxsackie B viruses (CVBs) associated with type 1 diabetes: a double-blind randomised placebo-controlled Phase I trial. Diabetologia. 2024; :. doi: 10.1007/s00125-024-06092-w. PubMed PMID:38369573 .
  9. Ruuska, SM, Tuisku, K, Holttinen, T, Kaltiala, R. All-cause and suicide mortalities among adolescents and young adults who contacted specialised gender identity services in Finland in 1996-2019: a register study. BMJ Ment Health. 2024;27 (1):. doi: 10.1136/bmjment-2023-300940. PubMed PMID:38367979 PubMed Central PMC10875569.
  10. Moja, L, Zanichelli, V, Mertz, D, Gandra, S, Cappello, B, Cooke, GS et al.. WHO’s essential medicines and AWaRe: recommendations on first- and second-choice antibiotics for empiric treatment of clinical infections. Clin Microbiol Infect. 2024; :. doi: 10.1016/j.cmi.2024.02.003. PubMed PMID:38342438 .
  11. Moell, A, Rozental, A, Buchmayer, S, Kaltiala, R, Långström, N. Effects of stricter legislation on coercive measures in child and adolescent psychiatric care: a qualitative interview study with staff. BMC Psychiatry. 2024;24 (1):102. doi: 10.1186/s12888-024-05553-1. PubMed PMID:38317134 PubMed Central PMC10845720.
  12. Linne, ML. Computational modeling of neuron-glia signaling interactions to unravel cellular and neural circuit functioning. Curr Opin Neurobiol. 2024;85 :102838. doi: 10.1016/j.conb.2023.102838. PubMed PMID:38310660 .
  13. Kurppa, K, Mulder, C, Stordal, K, Kaukinen, K. Celiac disease affects 1% of global population – who will manage all these patients? What are criteria to prioritize along risk for complications?. Gastroenterology. 2024; :. doi: 10.1053/j.gastro.2023.12.026. PubMed PMID:38290622 .
  14. Girchenko, P, Lahti-Pulkkinen, M, Hämäläinen, E, Laivuori, H, Villa, PM, Kajantie, E et al.. Associations of polymetabolic risk of high maternal pre-pregnancy body mass index with pregnancy complications, birth outcomes, and early childhood neurodevelopment: findings from two pregnancy cohorts. BMC Pregnancy Childbirth. 2024;24 (1):78. doi: 10.1186/s12884-024-06274-9. PubMed PMID:38267899 PubMed Central PMC10807109.
  15. Kisenge, R, Dhingra, U, Rees, CA, Liu, E, Dutta, A, Saikat, D et al.. Risk factors for moderate acute malnutrition among children with acute diarrhoea in India and Tanzania: a secondary analysis of data from a randomized trial. BMC Pediatr. 2024;24 (1):56. doi: 10.1186/s12887-024-04551-2. PubMed PMID:38238656 PubMed Central PMC10797730.
  16. Hazel, EA, Erchick, DJ, Katz, J, Lee, ACC, Diaz, M, Wu, LSF et al.. Neonatal mortality risk of vulnerable newborns by fine stratum of gestational age and birthweight for 230 679 live births in nine low- and middle-income countries, 2000-2017. BJOG. 2024; :. doi: 10.1111/1471-0528.17743. PubMed PMID:38228570 .
  17. Youssef, O, Loukola, A, Zidi-Mouaffak, YHS, Tamlander, M, Ruotsalainen, S, Kilpeläinen, E et al.. High-Resolution Genotyping of Formalin-Fixed Tissue Accurately Estimates Polygenic Risk Scores in Human Diseases. Lab Invest. 2024;104 (4):100325. doi: 10.1016/j.labinv.2024.100325. PubMed PMID:38220043 .
  18. Nurkkala, JM, Aittokallio, J, FinnGen
    , Kauko, A, Niiranen, T. Sex-specific genetic risks for adverse outcomes after coronary revascularization procedures. Interdiscip Cardiovasc Thorac Surg. 2024;38 (1):. doi: 10.1093/icvts/ivae006. PubMed PMID:38216540 PubMed Central PMC10799751.
  19. Nordström, EL, Kaltiala, R, Kristensen, P, Thimm, JC. Somatic symptoms and insomnia among bereaved parents and siblings eight years after the Utøya terror attack. Eur J Psychotraumatol. 2024;15 (1):2300585. doi: 10.1080/20008066.2023.2300585. PubMed PMID:38214224 PubMed Central PMC10791101.
  20. Katunin, E, Aitokari, L, Kivelä, L, Ilus, T, Huhtala, H, Kaukinen, K et al.. Measured levels of positive transglutaminase 2 antibodies are not associated with presentation or incidental endoscopic findings at celiac disease diagnosis. Scand J Gastroenterol. 2024; :1-6. doi: 10.1080/00365521.2023.2298709. PubMed PMID:38164975 .
  21. Toivonen, E, Taurio, K, Kortelainen, E, Havulinna, AS, FINNPEC, Jääskeläinen, T et al.. Validation of the Finnish Care register for Health Care diagnoses for preeclampsia, gestational diabetes and preterm delivery. Pregnancy Hypertens. 2024;35 :26-29. doi: 10.1016/j.preghy.2023.12.001. PubMed PMID:38091805 .
  22. Ojanperä, L, Lehtimäki, L, Kelemen, B, Csonka, P. Salbutamol delivery in small children: Effect of valved holding chamber and breathing patterns. J Allergy Clin Immunol Pract. 2024;12 (2):509-511.e3. doi: 10.1016/j.jaip.2023.11.013. PubMed PMID:37979688 .
  23. Magnusson, Å, Hanevik, HI, Laivuori, H, Loft, A, Piltonen, T, Pinborg, A et al.. Endometrial preparation protocols prior to frozen embryo transfer – convenience or safety?. Reprod Biomed Online. 2024;48 (1):103587. doi: 10.1016/j.rbmo.2023.103587. PubMed PMID:37949762 .
  24. Taavela, J, Kurppa, K, Jääskeläinen, T, Kaartinen, NE, Rissanen, H, Huhtala, H et al.. Trends in the prevalence rates and predictive factors of coeliac disease: A long-term nationwide follow-up study. Aliment Pharmacol Ther. 2024;59 (3):372-379. doi: 10.1111/apt.17803. PubMed PMID:37946663 .
  25. Ghimire, L, Ashorn, U. Exploring Adolescent girls’ Food-Talk in Kathmandu Valley, Nepal: A Qualitative Study. Ecol Food Nutr. 2024;63 (1):20-36. doi: 10.1080/03670244.2023.2274528. PubMed PMID:37936277 .
  26. Renlund, M, Tulppo, MP, Kivelä, A, Laivuori, H, Heinonen, S, Jääskeläinen, T et al.. Preeclampsia-exposed children’s heart rate variability 8-12 yr after index pregnancy: FINNCARE study. Am J Physiol Heart Circ Physiol. 2024;326 (1):H74-H81. doi: 10.1152/ajpheart.00540.2023. PubMed PMID:37921662 .
  27. Saarimäki, L, Kivistö, J, Palmu, S, Protudjer, JLP, Huhtala, H, Karjalainen, J et al.. Trends in severe allergic reactions of adults in Finland between 1999 and 2020: A national population study. Allergy. 2024;79 (1):252-254. doi: 10.1111/all.15929. PubMed PMID:37902169 .
  28. Monangi, NK, Xu, H, Fan, YM, Khanam, R, Khan, W, Deb, S et al.. Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis. Am J Clin Nutr. 2024;119 (1):221-231. doi: 10.1016/j.ajcnut.2023.10.011. PubMed PMID:37890672 PubMed Central PMC10808817.
  29. Vest, T, Rantanen, K, Verho, L, Aarnio, K, Korhonen, A, Richardt, A et al.. Etiology of intracerebral hemorrhage during pregnancy or puerperium: A nationwide study. Eur J Neurol. 2024;31 (3):e16012. doi: 10.1111/ene.16012. PubMed PMID:37532682 .
  30. Lehtimaki, M, Paunonen, L, Linne, ML. Accelerating Neural ODEs Using Model Order Reduction. IEEE Trans Neural Netw Learn Syst. 2024;35 (1):519-531. doi: 10.1109/TNNLS.2022.3175757. PubMed PMID:35617183 .
  31. Kivimäki, HM, Ståhl, TP, Joronen, KM, Rimpelä, AH. Parents’ Participation in School Health Examinations for Their Adolescent Children in Finland. J Sch Nurs. 2024;40 (2):189-199. doi: 10.1177/10598405211058841. PubMed PMID:34894843 PubMed Central PMC10924550.

Search PubMed

2023

  1. Aitokari, L, Lahti, S, Kivelä, L, Riekki, H, Hiltunen, P, Vuorela, N et al.. Alanine aminotransferase cutoffs for the pediatric fatty liver disease: Major impact of the reference population. J Pediatr Gastroenterol Nutr. 2023; :. doi: 10.1002/jpn3.12040. PubMed PMID:38314943 .
  2. Nigi, L, Laiho, JE, Hyöty, H, Dotta, F. Editorial: The contribution of viruses and innate immune system in the pathogenesis of type 1 diabetes. Front Endocrinol (Lausanne). 2023;14 :1335716. doi: 10.3389/fendo.2023.1335716. PubMed PMID:38161972 PubMed Central PMC10757338.
  3. Zapilko, V, Moisio, S, Parikka, M, Heinäniemi, M, Lohi, O. Generation of a Zebrafish Knock-In Model Recapitulating Childhood ETV6::RUNX1-Positive B-Cell Precursor Acute Lymphoblastic Leukemia. Cancers (Basel). 2023;15 (24):. doi: 10.3390/cancers15245821. PubMed PMID:38136366 PubMed Central PMC10871125.
  4. Jyskä, I, Turunen, M, Chaychi Maleki, A, Karppa, E, Palmu, S, Viik, J et al.. Effects of Using Guided Deep Breathing Exercises in a Virtual Natural Environment to Reduce Stress during Pediatric Treatment. Healthcare (Basel). 2023;11 (24):. doi: 10.3390/healthcare11243140. PubMed PMID:38132030 PubMed Central PMC10743274.
  5. Jyskä, I, Turunen, M, Chaychi Maleki, A, Karppa, E, Palmu, S, Mäkelä, J et al.. Design and User Experience of VirNE Application: Deep Breathing Exercise in a Virtual Natural Environment to Reduce Treatment Anxiety in Pediatrics. Healthcare (Basel). 2023;11 (24):. doi: 10.3390/healthcare11243129. PubMed PMID:38132019 PubMed Central PMC10743239.
  6. Toivonen, E, Taurio, K, Kortelainen, E, Havulinna, AS, FINNPEC, Jääskeläinen, T et al.. Validation of the Finnish Care register for Health Care diagnoses for preeclampsia, gestational diabetes and preterm delivery. Pregnancy Hypertens. 2024;35 :26-29. doi: 10.1016/j.preghy.2023.12.001. PubMed PMID:38091805 .
  7. Krali, O, Marincevic-Zuniga, Y, Arvidsson, G, Enblad, AP, Lundmark, A, Sayyab, S et al.. Multimodal classification of molecular subtypes in pediatric acute lymphoblastic leukemia. NPJ Precis Oncol. 2023;7 (1):131. doi: 10.1038/s41698-023-00479-5. PubMed PMID:38066241 PubMed Central PMC10709574.
  8. Lankinen, V, Vuorinen, RL, Helminen, M, Bakti, K, Välipakka, J, Laivuori, H et al.. Costs of abduction treatment in developmental dysplasia of the hip. Analysis of 900 patients. Ann Med. 2023;55 (2):2290694. doi: 10.1080/07853890.2023.2290694. PubMed PMID:38065688 PubMed Central PMC10836239.
  9. Rimpelä, A, Kesanto-Jokipolvi, H, Myöhänen, A, Heikonen, L, Oinas, S, Ahtiainen, R et al.. School and class closures and adolescent mental health during the second and later waves of the COVID-19 pandemic in Finland: a repeated cross-sectional study. BMC Public Health. 2023;23 (1):2434. doi: 10.1186/s12889-023-17342-8. PubMed PMID:38057763 PubMed Central PMC10702082.
  10. Hård Af Segerstad, EM, Mramba, LK, Liu, X, Uusitalo, U, Yang, J, Norris, J et al.. Associations of dietary patterns between age 9 and 24 months with risk of celiac disease autoimmunity and celiac disease among children at increased risk. Am J Clin Nutr. 2023;118 (6):1099-1105. doi: 10.1016/j.ajcnut.2023.08.009. PubMed PMID:38044022 .
  11. Nurmi, AK, Pelttari, LM, Kiiski, JI, Khan, S, Nurmikolu, M, Suvanto, M et al.. NTHL1 is a recessive cancer susceptibility gene. Sci Rep. 2023;13 (1):21127. doi: 10.1038/s41598-023-47441-w. PubMed PMID:38036545 PubMed Central PMC10689455.
  12. Nygård, L, Valta, M, Laine, AP, Toppari, J, Knip, M, Veijola, R et al.. CXADR polymorphism rs6517774 modifies islet autoimmunity characteristics and exhibits sex disparity. Front Genet. 2023;14 :1248701. doi: 10.3389/fgene.2023.1248701. PubMed PMID:38028613 PubMed Central PMC10651746.
  13. Nabirova, D, Horth, R, Kassabekova, L, Henderson, A, Yesmagambetova, A, Alaverdyan, S et al.. Corrigendum: Factors associated with COVID-19 vaccine confidence among primary care providers in Kazakhstan, March-April 2021. Front Public Health. 2023;11 :1308374. doi: 10.3389/fpubh.2023.1308374. PubMed PMID:38026420 PubMed Central PMC10660272.
  14. Lin, J, Moradi, E, Salenius, K, Lehtipuro, S, Häkkinen, T, Laiho, JE et al.. Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection. Nat Commun. 2023;14 (1):7630. doi: 10.1038/s41467-023-42763-9. PubMed PMID:37993433 PubMed Central PMC10665402.
  15. Ojanperä, L, Lehtimäki, L, Kelemen, B, Csonka, P. Salbutamol delivery in small children: Effect of valved holding chamber and breathing patterns. J Allergy Clin Immunol Pract. 2024;12 (2):509-511.e3. doi: 10.1016/j.jaip.2023.11.013. PubMed PMID:37979688 .
  16. Luoma, J, Adubra, L, Alber, D, Ashorn, P, Ashorn, U, Cloutman-Green, E et al.. Statistical analysis plan for the LAKANA trial: a cluster-randomized, placebo-controlled, double-blinded, parallel group, three-arm clinical trial testing the effects of mass drug administration of azithromycin on mortality and other outcomes among 1-11-month-old infants in Mali. Trials. 2023;24 (1):733. doi: 10.1186/s13063-023-07771-6. PubMed PMID:37968741 PubMed Central PMC10648361.
  17. Sievänen, H, Kari, J, Huurre, A, Palmu, S. A previous champagne tap reduces the probability of traumatic lumbar puncture in the following procedure. Sci Rep. 2023;13 (1):19626. doi: 10.1038/s41598-023-46407-2. PubMed PMID:37949913 PubMed Central PMC10638277.
  18. Magnusson, Å, Hanevik, HI, Laivuori, H, Loft, A, Piltonen, T, Pinborg, A et al.. Endometrial preparation protocols prior to frozen embryo transfer – convenience or safety?. Reprod Biomed Online. 2024;48 (1):103587. doi: 10.1016/j.rbmo.2023.103587. PubMed PMID:37949762 .
  19. Taavela, J, Kurppa, K, Jääskeläinen, T, Kaartinen, NE, Rissanen, H, Huhtala, H et al.. Trends in the prevalence rates and predictive factors of coeliac disease: A long-term nationwide follow-up study. Aliment Pharmacol Ther. 2024;59 (3):372-379. doi: 10.1111/apt.17803. PubMed PMID:37946663 .
  20. Gidado, S, Musa, M, Ba’aba, AI, Okeke, LA, Nguku, PM, Hadejia, IS et al.. Factors associated with health-seeking patterns among internally displaced persons in complex humanitarian emergency, Northeast Nigeria: a cross-sectional study. Confl Health. 2023;17 (1):54. doi: 10.1186/s13031-023-00552-7. PubMed PMID:37940958 PubMed Central PMC10630990.
  21. Rouvinen, H, Turunen, H, Lindfors, P, Kinnunen, JM, Rimpelä, A, Koivusilta, L et al.. Online health information-seeking behaviour and mental well-being among Finnish higher education students during COVID-19. Health Promot Int. 2023;38 (6):. doi: 10.1093/heapro/daad143. PubMed PMID:37935171 PubMed Central PMC10635413.
  22. Kaltiala, R, Holttinen, T, Tuisku, K. Have the psychiatric needs of people seeking gender reassignment changed as their numbers increase? A register study in Finland. Eur Psychiatry. 2023;66 (1):e93. doi: 10.1192/j.eurpsy.2023.2471. PubMed PMID:37929300 PubMed Central PMC10755572.
  23. Renlund, M, Tulppo, MP, Kivelä, A, Laivuori, H, Heinonen, S, Jääskeläinen, T et al.. Preeclampsia-exposed children’s heart rate variability 8-12 yr after index pregnancy: FINNCARE study. Am J Physiol Heart Circ Physiol. 2024;326 (1):H74-H81. doi: 10.1152/ajpheart.00540.2023. PubMed PMID:37921662 .
  24. Saarimäki, L, Kivistö, J, Palmu, S, Protudjer, JLP, Huhtala, H, Karjalainen, J et al.. Trends in severe allergic reactions of adults in Finland between 1999 and 2020: A national population study. Allergy. 2024;79 (1):252-254. doi: 10.1111/all.15929. PubMed PMID:37902169 .
  25. Monangi, NK, Xu, H, Fan, YM, Khanam, R, Khan, W, Deb, S et al.. Association of maternal prenatal copper concentration with gestational duration and preterm birth: a multicountry meta-analysis. Am J Clin Nutr. 2024;119 (1):221-231. doi: 10.1016/j.ajcnut.2023.10.011. PubMed PMID:37890672 PubMed Central PMC10808817.
  26. Pasanen, A, Karjalainen, MK, FinnGen, Zhang, G, Tiensuu, H, Haapalainen, AM et al.. Meta-analysis of genome-wide association studies of gestational duration and spontaneous preterm birth identifies new maternal risk loci. PLoS Genet. 2023;19 (10):e1010982. doi: 10.1371/journal.pgen.1010982. PubMed PMID:37871108 PubMed Central PMC10621942.
  27. Renlund, M, Jääskeläinen, T, Kivelä, A, Heinonen, S, Laivuori, H, Sarkola, T et al.. Determinants of vascular structure and function in at-risk children born to mothers managed for pre-eclampsia (FINNCARE study). Front Cardiovasc Med. 2023;10 :1264921. doi: 10.3389/fcvm.2023.1264921. PubMed PMID:37859683 PubMed Central PMC10582712.
  28. Benjamin-Chung, J, Mertens, A, Colford, JM Jr, Hubbard, AE, van der Laan, MJ, Coyle, J et al.. Author Correction: Early-childhood linear growth faltering in low- and middle-income countries. Nature. 2023;623 (7985):E2. doi: 10.1038/s41586-023-06703-3. PubMed PMID:37833392 PubMed Central PMC10620071.
  29. Lähdepuro, A, Lahti-Pulkkinen, M, Girchenko, P, Villa, PM, Heinonen, K, Lahti, J et al.. Positive maternal mental health during pregnancy and psychiatric problems in children from early childhood to late childhood. Dev Psychopathol. 2023; :1-13. doi: 10.1017/S0954579423001244. PubMed PMID:37814418 .
  30. Kinnunen, J, Nikkinen, H, Keikkala, E, Mustaniemi, S, Gissler, M, Laivuori, H et al.. Gestational diabetes is associated with the risk of offspring’s congenital anomalies: a register-based cohort study. BMC Pregnancy Childbirth. 2023;23 (1):708. doi: 10.1186/s12884-023-05996-6. PubMed PMID:37789251 PubMed Central PMC10548673.
  31. Krogvold, L, Mynarek, IM, Ponzi, E, Mørk, FB, Hessel, TW, Roald, T et al.. Pleconaril and ribavirin in new-onset type 1 diabetes: a phase 2 randomized trial. Nat Med. 2023;29 (11):2902-2908. doi: 10.1038/s41591-023-02576-1. PubMed PMID:37789144 PubMed Central PMC10667091.
  32. Lamichhane, S, Sen, P, Dickens, AM, Kråkström, M, Ilonen, J, Lempainen, J et al.. Circulating metabolic signatures of rapid and slow progression to type 1 diabetes in islet autoantibody-positive children. Front Endocrinol (Lausanne). 2023;14 :1211015. doi: 10.3389/fendo.2023.1211015. PubMed PMID:37745723 PubMed Central PMC10516565.
  33. Nabirova, D, Horth, R, Kassabekova, L, Henderson, A, Yesmagambetova, A, Alaverdyan, S et al.. Factors associated with COVID-19 vaccine confidence among primary care providers in Kazakhstan, March-April 2021. Front Public Health. 2023;11 :1245750. doi: 10.3389/fpubh.2023.1245750. PubMed PMID:37744481 PubMed Central PMC10517263.
  34. Hirvonen, MK, Lietzén, N, Moulder, R, Bhosale, SD, Koskenniemi, J, Vähä-Mäkilä, M et al.. Serum APOC1 levels are decreased in young autoantibody positive children who rapidly progress to type 1 diabetes. Sci Rep. 2023;13 (1):15941. doi: 10.1038/s41598-023-43039-4. PubMed PMID:37743383 PubMed Central PMC10518308.
  35. Wicaksono, WA, Cernava, T, Wassermann, B, Abdelfattah, A, Soto-Giron, MJ, Toledo, GV et al.. The edible plant microbiome: evidence for the occurrence of fruit and vegetable bacteria in the human gut. Gut Microbes. 2023;15 (2):2258565. doi: 10.1080/19490976.2023.2258565. PubMed PMID:37741805 PubMed Central PMC10519362.
  36. Perumal, N, Wang, D, Darling, AM, Liu, E, Wang, M, Ahmed, T et al.. Suboptimal gestational weight gain and neonatal outcomes in low and middle income countries: individual participant data meta-analysis. BMJ. 2023;382 :e072249. doi: 10.1136/bmj-2022-072249. PubMed PMID:37734757 PubMed Central PMC10512803.
  37. Kivelä, A, Heinonen, S, Kivinen, K, Kere, J, Kajantie, E, Jääskeläinen, T et al.. Hypertensive pregnancy complications and maternal characteristics as predictors of cardiovascular health within ten years after delivery. Pregnancy Hypertens. 2023;34 :5-12. doi: 10.1016/j.preghy.2023.09.001. PubMed PMID:37708664 .
  38. Mertens, A, Benjamin-Chung, J, Colford, JM Jr, Coyle, J, van der Laan, MJ, Hubbard, AE et al.. Causes and consequences of child growth faltering in low-resource settings. Nature. 2023;621 (7979):568-576. doi: 10.1038/s41586-023-06501-x. PubMed PMID:37704722 PubMed Central PMC10511328.
  39. Benjamin-Chung, J, Mertens, A, Colford, JM Jr, Hubbard, AE, van der Laan, MJ, Coyle, J et al.. Early-childhood linear growth faltering in low- and middle-income countries. Nature. 2023;621 (7979):550-557. doi: 10.1038/s41586-023-06418-5. PubMed PMID:37704719 PubMed Central PMC10511325.
  40. Vuori, MA, Kiiskinen, T, Pitkänen, N, Kurki, S, Laivuori, H, Laitinen, T et al.. Use of electronic health record data mining for heart failure subtyping. BMC Res Notes. 2023;16 (1):208. doi: 10.1186/s13104-023-06469-x. PubMed PMID:37697398 PubMed Central PMC10496250.
  41. Sady, H, Chaima, D, Hallamaa, L, Kortekangas, E, Ashorn, U, Banda, J et al.. Effect of dietary intervention on the prevalence of asymptomatic malaria among 6-18-month-old children in rural Malawi. Malar J. 2023;22 (1):266. doi: 10.1186/s12936-023-04701-4. PubMed PMID:37697296 PubMed Central PMC10496296.
  42. Kummola, L, González-Rodríguez, MI, Marnila, P, Nurminen, N, Salomaa, T, Hiihtola, L et al.. Comparison of the effect of autoclaved and non-autoclaved live soil exposure on the mouse immune system : Effect of soil exposure on immune system. BMC Immunol. 2023;24 (1):29. doi: 10.1186/s12865-023-00565-0. PubMed PMID:37689649 PubMed Central PMC10492337.
  43. Ahonen, I, Laurikka, P, Koskimaa, S, Huhtala, H, Lindfors, K, Kaukinen, K et al.. Prevalence of vomiting and nausea and associated factors after chronic and acute gluten exposure in celiac disease. BMC Gastroenterol. 2023;23 (1):301. doi: 10.1186/s12876-023-02934-w. PubMed PMID:37674120 PubMed Central PMC10481613.
  44. Vecchio, F, Carré, A, Korenkov, D, Zhou, Z, Apaolaza, P, Tuomela, S et al.. Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses. bioRxiv. 2023; :. doi: 10.1101/2023.08.19.553954. PubMed PMID:37662376 PubMed Central PMC10473604.
  45. Westergaard, D, Steinthorsdottir, V, Stefansdottir, L, Rohde, PD, Wu, X, Geller, F et al.. Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage. medRxiv. 2023; :. doi: 10.1101/2023.08.10.23293932. PubMed PMID:37645979 PubMed Central PMC10462219.
  46. Dotsenko, V, Sioofy-Khojine, AB, Hyöty, H, Viiri, K. Human intestinal organoid models for celiac disease research. Methods Cell Biol. 2023;179 :173-193. doi: 10.1016/bs.mcb.2023.01.008. PubMed PMID:37625874 .
  47. Lönnrot, M, Lynch, KF, Rewers, M, Lernmark, Å, Vehik, K, Akolkar, B et al.. Gastrointestinal Infections Modulate the Risk for Insulin Autoantibodies as the First-Appearing Autoantibody in the TEDDY Study. Diabetes Care. 2023;46 (11):1908-1915. doi: 10.2337/dc23-0518. PubMed PMID:37607456 PubMed Central PMC10620548.
  48. Mustaniemi, S, Keikkala, E, Kajantie, E, Nurhonen, M, Jylhä, A, Morin-Papunen, L et al.. Serum ceramides in early pregnancy as predictors of gestational diabetes. Sci Rep. 2023;13 (1):13274. doi: 10.1038/s41598-023-40224-3. PubMed PMID:37582815 PubMed Central PMC10427660.
  49. Uusitalo, U, Mramba, LK, Aronsson, CA, Vehik, K, Yang, J, Hummel, S et al.. HLA Genotype and Probiotics Modify the Association Between Timing of Solid Food Introduction and Islet Autoimmunity in the TEDDY Study. Diabetes Care. 2023;46 (10):1839-1847. doi: 10.2337/dc23-0417. PubMed PMID:37579501 PubMed Central PMC10516243.
  50. Julkunen, V, Schwarz, C, Kalapudas, J, Hallikainen, M, Piironen, AK, Mannermaa, A et al.. A FinnGen pilot clinical recall study for Alzheimer’s disease. Sci Rep. 2023;13 (1):12641. doi: 10.1038/s41598-023-39835-7. PubMed PMID:37537264 PubMed Central PMC10400697.
  51. Vest, T, Rantanen, K, Verho, L, Aarnio, K, Korhonen, A, Richardt, A et al.. Etiology of intracerebral hemorrhage during pregnancy or puerperium: A nationwide study. Eur J Neurol. 2024;31 (3):e16012. doi: 10.1111/ene.16012. PubMed PMID:37532682 .
  52. Krischer, JP, Lernmark, Å, Hagopian, WA, Rewers, MJ, McIndoe, R, Toppari, J et al.. SARS-CoV-2 – No Increased Islet Autoimmunity or Type 1 Diabetes in Teens. N Engl J Med. 2023;389 (5):474-475. doi: 10.1056/NEJMc2216477. PubMed PMID:37530831 PubMed Central PMC10481371.
  53. Karjalainen, M, Taittonen, L, Huhtala, H, Palmu, S, Tammela, O. Systematic analysis of adverse incident reports revealed the need for improvements in the neonatal unit. Acta Paediatr. 2023;112 (11):2322-2328. doi: 10.1111/apa.16918. PubMed PMID:37485868 .
  54. Sievänen, H, Kari, J, Aarnivala, H, Becker, S, Huurre, A, Långström, S et al.. Success and complications in lumbar punctures of pediatric patients with leukemia: a study protocol for a randomized clinical crossover trial of a bioimpedance needle system versus conventional procedure. Trials. 2023;24 (1):464. doi: 10.1186/s13063-023-07498-4. PubMed PMID:37475006 PubMed Central PMC10360266.
  55. Poutanen, R, Korppi, M, Csonka, P, Pauniaho, SL, Renko, M, Palmu, S et al.. Use of antibiotics contrary to guidelines for children’s lower respiratory tract infections in different health care settings. Eur J Pediatr. 2023;182 (10):4369-4377. doi: 10.1007/s00431-023-05099-6. PubMed PMID:37464182 PubMed Central PMC10587298.
  56. Batool, R, Yousafzai, MT, Qureshi, S, Muhammad, S, Qazi, I, Sadaf, T et al.. Parental acceptance of typhoid conjugate vaccine for children aged 6 months to 15 years in an outbreak setting of Lyari Town Karachi, Pakistan. Vaccine. 2023;41 (37):5376-5382. doi: 10.1016/j.vaccine.2023.07.003. PubMed PMID:37463829 PubMed Central PMC10448379.
  57. Laajala, M, Zwaagstra, M, Martikainen, M, Nekoua, MP, Benkahla, M, Sane, F et al.. Vemurafenib Inhibits Acute and Chronic Enterovirus Infection by Affecting Cellular Kinase Phosphatidylinositol 4-Kinase Type IIIβ. Microbiol Spectr. 2023;11 (4):e0055223. doi: 10.1128/spectrum.00552-23. PubMed PMID:37436162 PubMed Central PMC10433971.
  58. Matchado, A, Smith, JW, Schulze, KJ, Groopman, JD, Kortekangas, E, Chaima, D et al.. Child Aflatoxin Exposure is Associated with Poor Child Growth Outcomes: A Prospective Cohort Study in Rural Malawi. Curr Dev Nutr. 2023;7 (7):101962. doi: 10.1016/j.cdnut.2023.101962. PubMed PMID:37426291 PubMed Central PMC10328803.
  59. Ventelä, J, Alanko, A, Auvinen, A, Lohi, O, Nikkilä, A. Dual direction associations between common autoimmune diseases and leukemia among children and young adults: A systematic review. Cancer Epidemiol. 2023;86 :102411. doi: 10.1016/j.canep.2023.102411. PubMed PMID:37423102 .
  60. Riekki, H, Aitokari, L, Kivelä, L, Lahti, S, Hiltunen, P, Vuorela, N et al.. Prevalence and associated factors of metabolic-associated fatty liver disease in overweight Finnish children and adolescents. Front Endocrinol (Lausanne). 2023;14 :1090344. doi: 10.3389/fendo.2023.1090344. PubMed PMID:37409224 PubMed Central PMC10319394.
  61. Pavlinac, PB, Platts-Mills, J, Liu, J, Atlas, HE, Gratz, J, Operario, D et al.. Azithromycin for bacterial watery diarrhea: A reanalysis of the AntiBiotics for Children with severe Diarrhea (ABCD) trial incorporating molecular diagnostics. J Infect Dis. 2023; :. doi: 10.1093/infdis/jiad252. PubMed PMID:37405406 .
  62. Mäki-Marttunen, T, Blackwell, KT, Akkouh, I, Shadrin, A, Valstad, M, Elvsåshagen, T et al.. Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelling. bioRxiv. 2023; :. doi: 10.1101/2023.06.14.544920. PubMed PMID:37398070 PubMed Central PMC10312778.
  63. Viippola, E, Kuitunen, S, Rodosthenous, RS, Vabalas, A, Hartonen, T, Vartiainen, P et al.. Data Resource Profile: Nationwide registry data for high-throughput epidemiology and machine learning (FinRegistry). Int J Epidemiol. 2023;52 (4):e195-e200. doi: 10.1093/ije/dyad091. PubMed PMID:37365732 PubMed Central PMC10396416.
  64. Unger, HW, Hadiprodjo, AJ, Gutman, JR, Briand, V, Fievet, N, Valea, I et al.. Fetal sex and risk of pregnancy-associated malaria in Plasmodium falciparum-endemic regions: a meta-analysis. Sci Rep. 2023;13 (1):10310. doi: 10.1038/s41598-023-37431-3. PubMed PMID:37365258 PubMed Central PMC10293221.
  65. Heipertz, AE, Pajtler, KW, Pfaff, E, Schramm, K, Blattner-Johnson, M, Milde, T et al.. Outcome of Children and Adolescents With Relapsed/Refractory/Progressive Malignancies Treated With Molecularly Informed Targeted Drugs in the Pediatric Precision Oncology Registry INFORM. JCO Precis Oncol. 2023;7 :e2300015. doi: 10.1200/PO.23.00015. PubMed PMID:37364231 .
  66. Penninkangas, RM, Choudhary, MK, Mangani, C, Maleta, K, Teivaanmäki, T, Niemelä, O et al.. Low length-for-age Z-score within 1 month after birth predicts hyperdynamic circulation at the age of 21 years in rural Malawi. Sci Rep. 2023;13 (1):10283. doi: 10.1038/s41598-023-37269-9. PubMed PMID:37355681 PubMed Central PMC10290681.
  67. Renlund, MA, Jääskeläinen, TJ, Kivelä, ASE, Heinonen, ST, Laivuori, HM, Sarkola, TA et al.. Blood pressure, arterial stiffness, and cardiovascular risk profiles in 8-12-year-old children following preeclampsia (FINNCARE-study). J Hypertens. 2023;41 (9):1429-1437. doi: 10.1097/HJH.0000000000003485. PubMed PMID:37337860 PubMed Central PMC10399950.
  68. Kilpeläinen, L, Nikkilä, A, Lohi, O. Pre-harvest CD34 cell counts predicted peripheral blood stem cell collection yields. Acta Paediatr. 2023;112 (10):2189-2190. doi: 10.1111/apa.16879. PubMed PMID:37332113 .
  69. Näsänen-Gilmore, PK, Koivu, AM, Hunter, PJ, Muthiani, Y, Pörtfors, P, Heimonen, O et al.. A modular systematic review of antenatal interventions targeting modifiable environmental exposures in improving low birth weight. Am J Clin Nutr. 2023;117 Suppl 2 :S160-S169. doi: 10.1016/j.ajcnut.2022.11.029. PubMed PMID:37331762 .
  70. Koivu, AM, Näsänen-Gilmore, PK, Hunter, PJ, Muthiani, Y, Isojärvi, J, Heimonen, O et al.. Antenatal interventions to address harmful behaviors and psychosocial risk factors in the prevention of low birth weight. Am J Clin Nutr. 2023;117 Suppl 2 :S148-S159. doi: 10.1016/j.ajcnut.2022.11.028. PubMed PMID:37331761 .
  71. Hunter, PJ, Muthiani, Y, Näsänen-Gilmore, PK, Koivu, AM, Pörtfors, P, Bastola, K et al.. A modular systematic review of antenatal interventions to address undernutrition during pregnancy in the prevention of low birth weight. Am J Clin Nutr. 2023;117 Suppl 2 :S134-S147. doi: 10.1016/j.ajcnut.2023.01.024. PubMed PMID:37331760 .
  72. Muthiani, Y, Hunter, PJ, Näsänen-Gilmore, PK, Koivu, AM, Isojärvi, J, Luoma, J et al.. Antenatal interventions to reduce risk of low birth weight related to maternal infections during pregnancy. Am J Clin Nutr. 2023;117 Suppl 2 :S118-S133. doi: 10.1016/j.ajcnut.2023.02.025. PubMed PMID:37331759 .
  73. Koivu, AM, Haapaniemi, T, Askari, S, Bhandari, N, Black, RE, Chico, RM et al.. What more can be done? Prioritizing the most promising antenatal interventions to improve birth weight. Am J Clin Nutr. 2023;117 Suppl 2 (Suppl 2):S107-S117. doi: 10.1016/j.ajcnut.2022.10.022. PubMed PMID:37331758 PubMed Central PMC10447483.
  74. Ågren, R, Patil, S, Zhou, X, FinnGen., Sahlholm, K, Pääbo, S et al.. Major Genetic Risk Factors for Dupuytren’s Disease Are Inherited From Neandertals. Mol Biol Evol. 2023;40 (6):. doi: 10.1093/molbev/msad130. PubMed PMID:37315093 PubMed Central PMC10266526.
  75. Jones, SE, Maisha, FI, Strausz, SJ, Lammi, V, Cade, BE, Tervi, A et al.. The public health impact of poor sleep on severe COVID-19, influenza and upper respiratory infections. EBioMedicine. 2023;93 :104630. doi: 10.1016/j.ebiom.2023.104630. PubMed PMID:37301713 PubMed Central PMC10248098.
  76. Tyrmi, JS, Kaartokallio, T, Lokki, AI, Jääskeläinen, T, Kortelainen, E, Ruotsalainen, S et al.. Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy. JAMA Cardiol. 2023;8 (7):674-683. doi: 10.1001/jamacardio.2023.1312. PubMed PMID:37285119 PubMed Central PMC10248811.
  77. van Eijk, AM, Stepniewska, K, Hill, J, Taylor, SM, Rogerson, SJ, Cottrell, G et al.. Prevalence of and risk factors for microscopic and submicroscopic malaria infections in pregnancy: a systematic review and meta-analysis. Lancet Glob Health. 2023;11 (7):e1061-e1074. doi: 10.1016/S2214-109X(23)00194-8. PubMed PMID:37276878 PubMed Central PMC10880462.
  78. Popp, A, Laurikka, P, Czika, D, Kurppa, K. The role of gluten challenge in the diagnosis of celiac disease: a review. Expert Rev Gastroenterol Hepatol. 2023;17 (7):691-700. doi: 10.1080/17474124.2023.2219893. PubMed PMID:37243608 .
  79. Richardt, A, Aarnio, K, Korhonen, A, Rantanen, K, Verho, L, Laivuori, H et al.. Etiology and risk factors of ischemic stroke during pregnancy and puerperium: A population-based study. Eur Stroke J. 2023;8 (2):475-482. doi: 10.1177/23969873231170096. PubMed PMID:37231685 PubMed Central PMC10334185.
  80. Sormunen-Harju, H, Huvinen, E, Girchenko, PV, Kajantie, E, Villa, PM, Hämäläinen, EK et al.. Metabolomic Profiles of Nonobese and Obese Women With Gestational Diabetes. J Clin Endocrinol Metab. 2023;108 (11):2862-2870. doi: 10.1210/clinem/dgad288. PubMed PMID:37220084 PubMed Central PMC10584006.
  81. Miller, EC, Kauko, A, Tom, SE, Laivuori, H, Niiranen, T, Bello, NA et al.. Risk of Midlife Stroke After Adverse Pregnancy Outcomes: The FinnGen Study. Stroke. 2023;54 (7):1798-1805. doi: 10.1161/STROKEAHA.123.043052. PubMed PMID:37212139 PubMed Central PMC10330298.
  82. Rots, D, Jakub, TE, Keung, C, Jackson, A, Banka, S, Pfundt, R et al.. The clinical and molecular spectrum of the KDM6B-related neurodevelopmental disorder. Am J Hum Genet. 2023;110 (6):963-978. doi: 10.1016/j.ajhg.2023.04.008. PubMed PMID:37196654 PubMed Central PMC10257005.
  83. Ollila, HM, Sharon, E, Lin, L, Sinnott-Armstrong, N, Ambati, A, Yogeshwar, SM et al.. Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy. Nat Commun. 2023;14 (1):2709. doi: 10.1038/s41467-023-36120-z. PubMed PMID:37188663 PubMed Central PMC10185546.
  84. Ashorn, P, Ashorn, U, Muthiani, Y, Aboubaker, S, Askari, S, Bahl, R et al.. Small vulnerable newborns-big potential for impact. Lancet. 2023;401 (10389):1692-1706. doi: 10.1016/S0140-6736(23)00354-9. PubMed PMID:37167991 .
  85. Hunter, PJ, Awoyemi, T, Ayede, AI, Chico, RM, David, AL, Dewey, KG et al.. Biological and pathological mechanisms leading to the birth of a small vulnerable newborn. Lancet. 2023;401 (10389):1720-1732. doi: 10.1016/S0140-6736(23)00573-1. PubMed PMID:37167990 .
  86. Lawn, JE, Ohuma, EO, Bradley, E, Idueta, LS, Hazel, E, Okwaraji, YB et al.. Small babies, big risks: global estimates of prevalence and mortality for vulnerable newborns to accelerate change and improve counting. Lancet. 2023;401 (10389):1707-1719. doi: 10.1016/S0140-6736(23)00522-6. PubMed PMID:37167989 .
  87. Hofmeyr, GJ, Black, RE, Rogozińska, E, Heuer, A, Walker, N, Ashorn, P et al.. Evidence-based antenatal interventions to reduce the incidence of small vulnerable newborns and their associated poor outcomes. Lancet. 2023;401 (10389):1733-1744. doi: 10.1016/S0140-6736(23)00355-0. PubMed PMID:37167988 .
  88. Mohiddin, A, Semrau, KEA, Simon, J, Langlois, EV, Shiffman, J, Nabwera, H et al.. The ethical, economic, and developmental imperative to prevent small vulnerable newborns and stillbirths: essential actions to improve the country and global response. Lancet. 2023;401 (10389):1636-1638. doi: 10.1016/S0140-6736(23)00721-3. PubMed PMID:37167987 .
  89. K’Oloo, A, Godfrey, E, Koivu, AM, Barsosio, HC, Manji, K, Ndesangia, V et al.. Improving birth weight measurement and recording practices in Kenya and Tanzania: a prospective intervention study with historical controls. Popul Health Metr. 2023;21 (1):6. doi: 10.1186/s12963-023-00305-x. PubMed PMID:37165380 PubMed Central PMC10173481.
  90. Lokki, AI, Ren, Z, Triebwasser, M, Daly, E, FINNPEC, Perola, M et al.. Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study. BJOG. 2023;130 (12):1473-1482. doi: 10.1111/1471-0528.17529. PubMed PMID:37156755 PubMed Central PMC10592561.
  91. Hazel, EA, Erchick, DJ, Katz, J, Lee, ACC, Diaz, M, Wu, LSF et al.. Neonatal mortality risk of vulnerable newborns: A descriptive analysis of subnational, population-based birth cohorts for 238 203 live births in low- and middle-income settings from 2000 to 2017. BJOG. 2023; :. doi: 10.1111/1471-0528.17518. PubMed PMID:37156238 .
  92. Liu, X, Johnson, SB, Lynch, KF, Cordan, K, Pate, R, Butterworth, MD et al.. Physical Activity and the Development of Islet Autoimmunity and Type 1 Diabetes in 5- to 15-Year-Old Children Followed in the TEDDY Study. Diabetes Care. 2023;46 (7):1409-1416. doi: 10.2337/dc23-0036. PubMed PMID:37141102 PubMed Central PMC10300517.
  93. Kaltiala, R, Aalto-Setälä, T, Kiviruusu, O. Socioeconomic disparities in adolescent anxiety and depression in Finland have not increased during the COVID-19 pandemic. Scand J Public Health. 2023;51 (5):656-663. doi: 10.1177/14034948231166466. PubMed PMID:37088988 PubMed Central PMC10125881.
  94. Verho, L, Tikkanen, M, Äyräs, O, Aarnio, K, Rantanen, K, Korhonen, A et al.. Pregnancy-associated stroke and the recurrence of stroke and other complications in subsequent pregnancies: Population-based retrospective cohort study. BJOG. 2023;130 (11):1421-1429. doi: 10.1111/1471-0528.17503. PubMed PMID:37088716 .
  95. Tesler, F, Linne, ML, Destexhe, A. Modeling the relationship between neuronal activity and the BOLD signal: contributions from astrocyte calcium dynamics. Sci Rep. 2023;13 (1):6451. doi: 10.1038/s41598-023-32618-0. PubMed PMID:37081004 PubMed Central PMC10119111.
  96. Näsänen-Gilmore, P, Kumwenda, C, Nurhonen, M, Hallamaa, L, Mangani, C, Ashorn, P et al.. Body composition among Malawian young adolescents: Cross-validating predictive equations for bioelectric impedance analysis using deuterium dilution method. PLoS One. 2023;18 (4):e0284158. doi: 10.1371/journal.pone.0284158. PubMed PMID:37043498 PubMed Central PMC10096513.
  97. Voor, T, Pärtel, M, Peet, A, Saare, L, Hyöty, H, Knip, M et al.. Atopic sensitization in childhood depends on the type of green area around the home in infancy. Clin Exp Allergy. 2023;53 (8):850-853. doi: 10.1111/cea.14317. PubMed PMID:37038920 .
  98. Adu-Afarwuah, S, Arnold, CD, Lartey, A, Okronipa, H, Maleta, K, Ashorn, P et al.. Prevalence of morbidity symptoms among pregnant and postpartum women receiving different nutrient supplements in Ghana and Malawi: A secondary outcome analysis of two randomised controlled trials. Matern Child Nutr. 2023;19 (3):e13501. doi: 10.1111/mcn.13501. PubMed PMID:37021807 PubMed Central PMC10262897.
  99. Walsh, EE, Pérez Marc, G, Zareba, AM, Falsey, AR, Jiang, Q, Patton, M et al.. Efficacy and Safety of a Bivalent RSV Prefusion F Vaccine in Older Adults. N Engl J Med. 2023;388 (16):1465-1477. doi: 10.1056/NEJMoa2213836. PubMed PMID:37018468 .
  100. Lankinen, V, Helminen, M, Bakti, K, Välipakka, J, Laivuori, H, Hyvärinen, A et al.. Known risk factors of the developmental dysplasia of the hip predicting more severe clinical presentation and failure of Pavlik harness treatment. BMC Pediatr. 2023;23 (1):148. doi: 10.1186/s12887-023-03935-0. PubMed PMID:37004001 PubMed Central PMC10064754.
  101. Lohiniva, AL, Hussein, I, Lehtinen, JM, Sivelä, J, Hyökki, S, Nohynek, H et al.. Qualitative Insights into Vaccine Uptake of Nursing Staff in Long-Term Care Facilities in Finland. Vaccines (Basel). 2023;11 (3):. doi: 10.3390/vaccines11030530. PubMed PMID:36992113 PubMed Central PMC10056830.
  102. Sioofy-Khojine, AB, Lehtonen, JP, Nurminen, N, Laiho, JE, Toppari, J, Veijola, R et al.. HLA-DQ-conferred risk for type 1 diabetes does not alter neutralizing antibody response to a widely used enterovirus vaccine, the poliovirus vaccine. J Med Virol. 2023;95 (4):e28707. doi: 10.1002/jmv.28707. PubMed PMID:36971180 .
  103. Manninen, T, Aćimović, J, Linne, ML. Analysis of Network Models with Neuron-Astrocyte Interactions. Neuroinformatics. 2023;21 (2):375-406. doi: 10.1007/s12021-023-09622-w. PubMed PMID:36959372 PubMed Central PMC10085960.
  104. Hakkarainen, M, Kaaja, I, Douglas, SPM, Vulliamy, T, Dokal, I, Soulier, J et al.. The clinical picture of ERCC6L2 disease: from bone marrow failure to acute leukemia. Blood. 2023;141 (23):2853-2866. doi: 10.1182/blood.2022019425. PubMed PMID:36952636 .
  105. Fischer, A, Lersch, R, de Andrade Krätzig, N, Strong, A, Friedrich, MJ, Weber, J et al.. interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution. Cell Genom. 2023;3 (3):100276. doi: 10.1016/j.xgen.2023.100276. PubMed PMID:36950387 PubMed Central PMC10025556.
  106. Hirose, H, Nakano, S, Matsuda, H, Sakakibara, T, Imagawa, H, Kawashima, Y et al.. Evaluation of coronary revascularization for ischemic heart disease: in the consecutive 200 cases. Jpn Circ J. 1987;51 (9):1048-51. doi: 10.1253/jcj.51.1048. PubMed PMID:3694768 .

Search PubMed

2022

  1. Nurkkala, J, Kauko, A, FinnGen,, Laivuori, H, Saarela, T, Tyrmi, JS et al.. Associations of polygenic risk scores for preeclampsia and blood pressure with hypertensive disorders of pregnancy. J Hypertens. 2023;41 (3):380-387. doi: 10.1097/HJH.0000000000003336. PubMed PMID:36947680 PubMed Central PMC9894151.
  2. Perez-Villatoro, F, Oikkonen, J, Casado, J, Chernenko, A, Gulhan, DC, Tumiati, M et al.. Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer. NPJ Precis Oncol. 2022;6 (1):96. doi: 10.1038/s41698-022-00339-8. PubMed PMID:36581696 PubMed Central PMC9800569.
  3. Peterziel, H, Jamaladdin, N, ElHarouni, D, Gerloff, XF, Herter, S, Fiesel, P et al.. Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM. NPJ Precis Oncol. 2022;6 (1):94. doi: 10.1038/s41698-022-00335-y. PubMed PMID:36575299 PubMed Central PMC9794727.
  4. Vatanen, T, Jabbar, KS, Ruohtula, T, Honkanen, J, Avila-Pacheco, J, Siljander, H et al.. Mobile genetic elements from the maternal microbiome shape infant gut microbial assembly and metabolism. Cell. 2022;185 (26):4921-4936.e15. doi: 10.1016/j.cell.2022.11.023. PubMed PMID:36563663 PubMed Central PMC9869402.
  5. Korppi, M, Palmu, S, Heikkilä, P, Csonka, P. Antibiotic prescriptions for child sinusitis varied between specialties after Finnish guidelines were updated in 2018. Acta Paediatr. 2023;112 (5):1041-1048. doi: 10.1111/apa.16641. PubMed PMID:36562286 .
  6. Wicaksono, WA, Buko, A, Kusstatscher, P, Cernava, T, Sinkkonen, A, Laitinen, OH et al.. Impact of Cultivation and Origin on the Fruit Microbiome of Apples and Blueberries and Implications for the Exposome. Microb Ecol. 2022; :. doi: 10.1007/s00248-022-02157-8. PubMed PMID:36542126 .
  7. Bakti, K, Lankinen, V, Helminen, M, Välipakka, J, Laivuori, H, Hyvärinen, A et al.. Clinical and sonographic improvement of developmental dysplasia of the hip: analysis of 948 patients. J Orthop Surg Res. 2022;17 (1):538. doi: 10.1186/s13018-022-03432-7. PubMed PMID:36510263 PubMed Central PMC9743506.
  8. Sheikh, J, Allotey, J, Kew, T, Fernández-Félix, BM, Zamora, J, Khalil, A et al.. Effects of race and ethnicity on perinatal outcomes in high-income and upper-middle-income countries: an individual participant data meta-analysis of 2 198 655 pregnancies. Lancet. 2022;400 (10368):2049-2062. doi: 10.1016/S0140-6736(22)01191-6. PubMed PMID:36502843 .
  9. Mustaniemi, S, Morin-Papunen, L, Keikkala, E, Öhman, H, Surcel, HM, Kaaja, R et al.. Associations of low sex hormone-binding globulin and androgen excess in early pregnancy with fasting and post-prandial hyperglycaemia, gestational diabetes, and its severity. Diabetes Metab Res Rev. 2023;39 (2):e3599. doi: 10.1002/dmrr.3599. PubMed PMID:36484476 PubMed Central PMC10078580.
  10. Tauschi, R, Eurén, A, Vuorela, N, Koskimaa, S, Huhtala, H, Kaukinen, K et al.. Association of concomitant autoimmunity with the disease features and long-term treatment and health outcomes in Celiac disease. Front Med (Lausanne). 2022;9 :1055135. doi: 10.3389/fmed.2022.1055135. PubMed PMID:36465913 PubMed Central PMC9709120.
  11. Hakola, L, Oikarinen, M, Niinistö, S, Cuthbertson, D, Lehtonen, J, Puustinen, L et al.. Serum 25-hydroxyvitamin D and fatty acids in relation to the risk of microbial infections in children: The TRIGR Divia study. Clin Nutr. 2022;41 (12):2729-2739. doi: 10.1016/j.clnu.2022.10.017. PubMed PMID:36368258 .
  12. Koivusilta, L, Kaltiala, R, Myöhänen, A, Hotulainen, R, Rimpelä, A. A Chronic Disease in Adolescence and Selection to an Educational Path-A Longitudinal Study. Int J Environ Res Public Health. 2022;19 (21):. doi: 10.3390/ijerph192114407. PubMed PMID:36361283 PubMed Central PMC9657637.
  13. Korhonen, A, Verho, L, Aarnio, K, Rantanen, K, Saaros, A, Laivuori, H et al.. Subarachnoid Hemorrhage During Pregnancy and Puerperium: A Population-Based Study. Stroke. 2023;54 (1):198-207. doi: 10.1161/STROKEAHA.122.039235. PubMed PMID:36321452 .
  14. Linnansaari, A, Schreuders, M, Kunst, AE, SILNE-R -study group, Lindfors, P. Facilitating conditions for staff’s confidence to enforce school tobacco policies: qualitative analysis from seven European cities. Implement Sci Commun. 2022;3 (1):113. doi: 10.1186/s43058-022-00362-7. PubMed PMID:36273225 PubMed Central PMC9588223.
  15. Czamara, D, Cruceanu, C, Lahti-Pulkkinen, M, Dieckmann, L, Ködel, M, Sauer, S et al.. Genome-Wide Copy Number Variant and High-Throughput Transcriptomics Analyses of Placental Tissues Underscore Persisting Child Susceptibility in At-Risk Pregnancies Cleared in Standard Genetic Testing. Int J Mol Sci. 2022;23 (19):. doi: 10.3390/ijms231911448. PubMed PMID:36232765 PubMed Central PMC9569583.
  16. Mtove, G, Minja, DTR, Abdul, O, Gesase, S, Maleta, K, Divala, TH et al.. The choice of reference chart affects the strength of the association between malaria in pregnancy and small for gestational age: an individual participant data meta-analysis comparing the Intergrowth-21 with a Tanzanian birthweight chart. Malar J. 2022;21 (1):292. doi: 10.1186/s12936-022-04307-2. PubMed PMID:36224585 PubMed Central PMC9559842.
  17. Stahl, M, Li, Q, Lynch, K, Koletzko, S, Mehta, P, Gragert, L et al.. Incidence of Pediatric Celiac Disease Varies by Region. Am J Gastroenterol. 2023;118 (3):539-545. doi: 10.14309/ajg.0000000000002056. PubMed PMID:36219178 PubMed Central PMC9991947.
  18. Virta, J, Hannula, M, Lindfors, K, Tamminen, I, Taavela, J, Huhtala, H et al.. Validation of the X-ray microtomography in the assessment of duodenal morphometry and surface area in celiac disease. Front Immunol. 2022;13 :945197. doi: 10.3389/fimmu.2022.945197. PubMed PMID:36211435 PubMed Central PMC9539806.
  19. Pilheden, M, Ahlgren, L, Hyrenius-Wittsten, A, Gonzalez-Pena, V, Sturesson, H, Hansen Marquart, HV et al.. Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia. Hemasphere. 2022;6 (10):e785. doi: 10.1097/HS9.0000000000000785. PubMed PMID:36204688 PubMed Central PMC9529062.
  20. Rodosthenous, RS, Niemi, MEK, Kallio, L, Perala, M, Terho, P, Knopp, T et al.. Recontacting biobank participants to collect lifestyle, behavioural and cognitive information via online questionnaires: lessons from a pilot study within FinnGen. BMJ Open. 2022;12 (10):e064695. doi: 10.1136/bmjopen-2022-064695. PubMed PMID:36198465 PubMed Central PMC9535212.
  21. Arad-Cohen, N, Zeller, B, Abrahamsson, J, Fernandez Navarro, JM, Cheuk, D, Palmu, S et al.. Supportive care in pediatric acute myeloid leukemia:Expert-based recommendations of the NOPHO-DB-SHIP consortium. Expert Rev Anticancer Ther. 2022;22 (11):1183-1196. doi: 10.1080/14737140.2022.2131544. PubMed PMID:36191604 .
  22. Airikka, A, Lahti-Pulkkinen, M, Tuovinen, S, Heinonen, K, Lahti, J, Girchenko, P et al.. Maternal exposure to childhood maltreatment and mental and behavioral disorders in children. Eur Child Adolesc Psychiatry. 2022; :. doi: 10.1007/s00787-022-02090-8. PubMed PMID:36181574 .
  23. Stone, VM, Utorova, R, Butrym, M, Sioofy-Khojine, AB, Hankaniemi, MM, Ringqvist, EE et al.. Coxsackievirus B infections are common in Cystic Fibrosis and experimental evidence supports protection by vaccination. iScience. 2022;25 (10):105070. doi: 10.1016/j.isci.2022.105070. PubMed PMID:36157581 PubMed Central PMC9490033.
  24. Oaks, BM, Adu-Afarwuah, S, Ashorn, P, Lartey, A, Laugero, KD, Okronipa, H et al.. Increased risk of preterm delivery with high cortisol during pregnancy is modified by fetal sex: a cohort study. BMC Pregnancy Childbirth. 2022;22 (1):727. doi: 10.1186/s12884-022-05061-8. PubMed PMID:36151538 PubMed Central PMC9502964.
  25. Vehik, K, Boulware, D, Killian, M, Rewers, M, McIndoe, R, Toppari, J et al.. Rising Hemoglobin A1c in the Nondiabetic Range Predicts Progression of Type 1 Diabetes As Well As Oral Glucose Tolerance Tests. Diabetes Care. 2022;45 (10):2342-2349. doi: 10.2337/dc22-0828. PubMed PMID:36150054 PubMed Central PMC9587339.
  26. Krischer, JP, Liu, X, Lernmark, Å, Hagopian, WA, Rewers, MJ, She, JX et al.. Predictors of the Initiation of Islet Autoimmunity and Progression to Multiple Autoantibodies and Clinical Diabetes: The TEDDY Study. Diabetes Care. 2022;45 (10):2271-2281. doi: 10.2337/dc21-2612. PubMed PMID:36150053 PubMed Central PMC9643148.
  27. Liu, E, Wang, D, Darling, AM, Perumal, N, Wang, M, Ahmed, T et al.. Effects of prenatal nutritional supplements on gestational weight gain in low- and middle-income countries: a meta-analysis of individual participant data. Am J Clin Nutr. 2022;116 (6):1864-1876. doi: 10.1093/ajcn/nqac259. PubMed PMID:36130877 .
  28. Luoma, J, Adubra, L, Ashorn, P, Ashorn, U, Bendabenda, J, Dewey, KG et al.. Association between asymptomatic infections and linear growth in 18-24-month-old Malawian children. Matern Child Nutr. 2023;19 (1):e13417. doi: 10.1111/mcn.13417. PubMed PMID:36111423 PubMed Central PMC9749610.
  29. Kröger, S, Repo, M, Hiltunen, P, Vornanen, M, Huhtala, H, Kivelä, L et al.. Differential diagnosis and long-term outcomes of non-atrophic duodenal changes in children. Front Pediatr. 2022;10 :982623. doi: 10.3389/fped.2022.982623. PubMed PMID:36105857 PubMed Central PMC9464825.
  30. Csonka, P, Palmu, S, Heikkilä, P, Huhtala, H, Korppi, M. Outpatient Antibiotic Prescribing for 357,390 Children With Otitis Media. Pediatr Infect Dis J. 2022;41 (12):947-952. doi: 10.1097/INF.0000000000003693. PubMed PMID:36102742 PubMed Central PMC9645548.
  31. Wicaksono, WA, Buko, A, Kusstatscher, P, Sinkkonen, A, Laitinen, OH, Virtanen, SM et al.. Modulation of the food microbiome by apple fruit processing. Food Microbiol. 2022;108 :104103. doi: 10.1016/j.fm.2022.104103. PubMed PMID:36088117 .
  32. Liu, Z, Fan, YM, Ashorn, P, Chingwanda, C, Maleta, K, Hallamaa, L et al.. Lack of Associations between Environmental Exposures and Environmental Enteric Dysfunction among 18-Month-Old Children in Rural Malawi. Int J Environ Res Public Health. 2022;19 (17):. doi: 10.3390/ijerph191710891. PubMed PMID:36078607 PubMed Central PMC9517768.
  33. Pukkila, J, Mustaniemi, S, Lingaiah, S, Lappalainen, OP, Kajantie, E, Pouta, A et al.. Increased Oral Care Needs and Third Molar Symptoms in Women with Gestational Diabetes Mellitus: A Finnish Gestational Diabetes Case-Control Study. Int J Environ Res Public Health. 2022;19 (17):. doi: 10.3390/ijerph191710711. PubMed PMID:36078430 PubMed Central PMC9518339.
  34. Nuorti, JP, Rinta-Kokko, H, Toropainen, M, Siira, L, Nohynek, H, Palmu, AA et al.. Long-term population impact of infant 10-valent pneumococcal conjugate vaccination on invasive pneumococcal disease in adults in Finland. Vaccine. 2022;40 (41):5950-5958. doi: 10.1016/j.vaccine.2022.08.047. PubMed PMID:36075797 .
  35. Kekki, M, Koukkula, T, Salonen, A, Gissler, M, Laivuori, H, Huttunen, TT et al.. Birth injury in breech delivery: a nationwide population-based cohort study in Finland. Arch Gynecol Obstet. 2022; :. doi: 10.1007/s00404-022-06772-1. PubMed PMID:36074174 .
  36. Dewey, KG, Arnold, CD, Wessells, KR, Prado, EL, Abbeddou, S, Adu-Afarwuah, S et al.. Preventive small-quantity lipid-based nutrient supplements reduce severe wasting and severe stunting among young children: an individual participant data meta-analysis of randomized controlled trials. Am J Clin Nutr. 2022;116 (5):1314-1333. doi: 10.1093/ajcn/nqac232. PubMed PMID:36045000 .
  37. Kaltiala, R. Aspects of Gender and Sexuality in Relation to Experiences of Subjection to Sexual Harassment among Adolescents in General Population. Int J Environ Res Public Health. 2022;19 (16):. doi: 10.3390/ijerph19169811. PubMed PMID:36011437 PubMed Central PMC9408105.
  38. Fu, JM, Satterstrom, FK, Peng, M, Brand, H, Collins, RL, Dong, S et al.. Rare coding variation provides insight into the genetic architecture and phenotypic context of autism. Nat Genet. 2022;54 (9):1320-1331. doi: 10.1038/s41588-022-01104-0. PubMed PMID:35982160 PubMed Central PMC9653013.
  39. Ruotsalainen, SE, Surakka, I, Mars, N, Karjalainen, J, Kurki, M, Kanai, M et al.. Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis. Commun Biol. 2022;5 (1):802. doi: 10.1038/s42003-022-03552-0. PubMed PMID:35978133 PubMed Central PMC9385630.
  40. Girchenko, P, Lahti-Pulkkinen, M, Lipsanen, J, Heinonen, K, Lahti, J, Rantalainen, V et al.. Maternal early-pregnancy body mass index-associated metabolomic component and mental and behavioral disorders in children. Mol Psychiatry. 2022;27 (11):4653-4661. doi: 10.1038/s41380-022-01723-3. PubMed PMID:35948657 PubMed Central PMC9734035.
  41. Sinha, B, Sommerfelt, H, Ashorn, P, Mazumder, S, Taneja, S, Bahl, R et al.. Effect of community-initiated kangaroo mother care on breastfeeding performance in low birthweight infants: A randomized clinical trial. Matern Child Nutr. 2022;18 (4):e13419. doi: 10.1111/mcn.13419. PubMed PMID:35946487 PubMed Central PMC9480911.
  42. Holttinen, T, Lindberg, N, Rissanen, P, Kaltiala, R. Educational attainment of adolescents treated in psychiatric inpatient care: a register study over 3 decades. Eur Child Adolesc Psychiatry. 2022; :. doi: 10.1007/s00787-022-02052-0. PubMed PMID:35932327 .
  43. Roslund, MI, Parajuli, A, Hui, N, Puhakka, R, Grönroos, M, Soininen, L et al.. A Placebo-controlled double-blinded test of the biodiversity hypothesis of immune-mediated diseases: Environmental microbial diversity elicits changes in cytokines and increase in T regulatory cells in young children. Ecotoxicol Environ Saf. 2022;242 :113900. doi: 10.1016/j.ecoenv.2022.113900. PubMed PMID:35930838 .
  44. Repo, M, Kurppa, K, Huhtala, H, Luostarinen, L, Kaukinen, K, Kivelä, L et al.. Significance of low ferritin without anaemia in screen-detected, adult coeliac disease patients. J Intern Med. 2022;292 (6):904-914. doi: 10.1111/joim.13548. PubMed PMID:35925673 PubMed Central PMC9805163.
  45. Andersson, NG, Rathe, M, Mølle, I, Jarvis, KB, Hoffmann, M, Huurre, A et al.. A survey on thromboprophylaxis and coagulation assessment in children and young adults with acute lymphoblastic leukaemia (ALL) in the Nordic and Baltic countries: Different practices of assessment and management. Br J Haematol. 2022;199 (1):117-121. doi: 10.1111/bjh.18397. PubMed PMID:35922061 PubMed Central PMC9804349.
  46. Salenius, M, Pyykkö, J, Ashorn, U, Dewey, KG, Gondwe, A, Harjunmaa, U et al.. Association between prenatal provision of lipid-based nutrient supplements and caesarean delivery: Findings from a randomised controlled trial in Malawi. Matern Child Nutr. 2022;18 (4):e13414. doi: 10.1111/mcn.13414. PubMed PMID:35909334 PubMed Central PMC9480947.
  47. Vihikangas, T, Palmu, S, Koivisto, AM, Heikkilä, P. Changes in Bronchiolitis Incidence During the Last Two Decades in Tampere, Finland: A Retrospective Study. Pediatr Infect Dis J. 2022;41 (11):867-871. doi: 10.1097/INF.0000000000003662. PubMed PMID:35895894 PubMed Central PMC9555828.
  48. Sioofy-Khojine, AB, Richardson, SJ, Locke, JM, Oikarinen, S, Nurminen, N, Laine, AP et al.. Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage. Diabetologia. 2022;65 (10):1701-1709. doi: 10.1007/s00125-022-05753-y. PubMed PMID:35867130 PubMed Central PMC9477938.
  49. Kivioja, A, Toivonen, E, Tyrmi, J, Ruotsalainen, S, Ripatti, S, Huhtala, H et al.. Increased Risk of Preeclampsia in Women With a Genetic Predisposition to Elevated Blood Pressure. Hypertension. 2022;79 (9):2008-2015. doi: 10.1161/HYPERTENSIONAHA.122.18996. PubMed PMID:35862124 PubMed Central PMC9370253.
  50. Abuhamed, J, Nikkilä, A, Raitanen, J, Alimam, W, Lohi, O, Pitkäniemi, J et al.. Incidence trends of childhood central nervous system tumors in Finland 1990-2017. BMC Cancer. 2022;22 (1):784. doi: 10.1186/s12885-022-09862-0. PubMed PMID:35850678 PubMed Central PMC9290294.
  51. Csonka, P. Anaphylaxis from mango puree contaminated by mango seeds. J Allergy Clin Immunol Pract. 2022;10 (10):2750-2751. doi: 10.1016/j.jaip.2022.06.047. PubMed PMID:35850463 .
  52. Vuolle, S, Laurikka, P, Repo, M, Huhtala, H, Kaukinen, K, Kurppa, K et al.. Persistent symptoms are diverse and associated with health concerns and impaired quality of life in patients with paediatric coeliac disease diagnosis after transition to adulthood. BMJ Open Gastroenterol. 2022;9 (1):. doi: 10.1136/bmjgast-2022-000914. PubMed PMID:35820709 PubMed Central PMC9277401.
  53. Laurikka, P, Kivelä, L, Kurppa, K, Kaukinen, K. Review article: Systemic consequences of coeliac disease. Aliment Pharmacol Ther. 2022;56 Suppl 1 (Suppl 1):S64-S72. doi: 10.1111/apt.16912. PubMed PMID:35815828 PubMed Central PMC9543231.
  54. Linnansaari, A, Ollila, H, Pisinger, C, Scheffels, J, Kinnunen, JM, Rimpelä, A et al.. Towards Tobacco-Free Generation: implementation of preventive tobacco policies in the Nordic countries. Scand J Public Health. 2022; :14034948221106867. doi: 10.1177/14034948221106867. PubMed PMID:35799463 .
  55. Vuorenoja, S, Vettenranta, K, Lohi, O. Successful eradication of chronic myeloid leukemia in a child despite allogeneic graft rejection. Cancer Rep (Hoboken). 2022;5 (10):e1663. doi: 10.1002/cnr2.1663. PubMed PMID:35796282 PubMed Central PMC9575499.
  56. Eriksson, O, Bhalla, US, Blackwell, KT, Crook, SM, Keller, D, Kramer, A et al.. Combining hypothesis- and data-driven neuroscience modeling in FAIR workflows. Elife. 2022;11 :. doi: 10.7554/eLife.69013. PubMed PMID:35792600 PubMed Central PMC9259018.
  57. Rannikko, J, Viskari, H, Sirkeoja, S, Tamminen, P, Kaila, V, Ala-Mursula, A et al.. Population-Based Assessment of Contact Tracing Operations for Coronavirus Disease 2019 in Pirkanmaa Hospital District, Finland. Open Forum Infect Dis. 2022;9 (7):ofac214. doi: 10.1093/ofid/ofac214. PubMed PMID:35791357 PubMed Central PMC9047225.
  58. Mearin, ML, Agardh, D, Antunes, H, Al-Toma, A, Auricchio, R, Castillejo, G et al.. ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease. J Pediatr Gastroenterol Nutr. 2022;75 (3):369-386. doi: 10.1097/MPG.0000000000003540. PubMed PMID:35758521 .
  59. Karvonen, M, Goth, K, Eloranta, SJ, Kaltiala, R. Identity Integration in Adolescents With Features of Gender Dysphoria Compared to Adolescents in General Population. Front Psychiatry. 2022;13 :848282. doi: 10.3389/fpsyt.2022.848282. PubMed PMID:35757222 PubMed Central PMC9218247.
  60. Kekki, M, Salonen, A, Koukkula, T, Laivuori, H, Tihtonen, K, Huttunen, TT et al.. Incidence changes in risk factors associated with the decreasing number of birth-related clavicle fractures in Finland: A nationwide retrospective birth cohort from 2004 to 2017. Birth. 2023;50 (2):428-437. doi: 10.1111/birt.12662. PubMed PMID:35735132 .
  61. Kivelä, L, Eurén, A, Repo, M, Huhtala, H, Kaukinen, K, Kurppa, K et al.. Coexisting Type 1 Diabetes, Persistent Symptoms, and Financial Issues Associate With Poorer Adherence to a Gluten-Free Diet in Celiac Disease After Transition From Pediatrics to Adult Care. Front Nutr. 2022;9 :883220. doi: 10.3389/fnut.2022.883220. PubMed PMID:35719146 PubMed Central PMC9200750.
  62. Laajala, E, Kalim, UU, Grönroos, T, Rasool, O, Halla-Aho, V, Konki, M et al.. Umbilical cord blood DNA methylation in children who later develop type 1 diabetes. Diabetologia. 2022;65 (9):1534-1540. doi: 10.1007/s00125-022-05726-1. PubMed PMID:35716175 PubMed Central PMC9345803.
  63. Alber, D, Haidara, FC, Luoma, J, Adubra, L, Ashorn, P, Ashorn, U et al.. SARS-CoV-2 infection and antibody seroprevalence in routine surveillance patients, healthcare workers and general population in Kita region, Mali: an observational study 2020-2021. BMJ Open. 2022;12 (6):e060367. doi: 10.1136/bmjopen-2021-060367. PubMed PMID:35710236 PubMed Central PMC9207578.
  64. Nikkilä, A, Lohi, O, Nieminen, N, Csonka, P. Trends in ferritin measurements in children and adolescents: A Finnish 9-year observational study. Acta Paediatr. 2022;111 (10):1933-1940. doi: 10.1111/apa.16454. PubMed PMID:35708115 PubMed Central PMC9541652.
  65. Kivelä, L, Kurppa, K. Letter to the Editor for the article “20-year follow-up study of celiac patients identified in a mass school screening: compliance to gluten-free diet and autoimmunity”. J Pediatr Gastroenterol Nutr. 2022;74 (4):e101. doi: 10.1097/MPG.0000000000003351. PubMed PMID:35703950 .
  66. Laiho, JE, Laitinen, OH, Malkamäki, J, Puustinen, L, Sinkkonen, A, Pärkkä, J et al.. Exposomic determinants of immune-mediated diseases: Special focus on type 1 diabetes, celiac disease, asthma, and allergies: The HEDIMED project approach. Environ Epidemiol. 2022;6 (3):e212. doi: 10.1097/EE9.0000000000000212. PubMed PMID:35702504 PubMed Central PMC9187189.
  67. Niinistö, S, Miettinen, ME, Cuthbertson, D, Honkanen, J, Hakola, L, Autio, R et al.. Associations Between Serum Fatty Acids and Immunological Markers in Children Developing Islet Autoimmunity-The TRIGR Nested Case-Control Study. Front Immunol. 2022;13 :858875. doi: 10.3389/fimmu.2022.858875. PubMed PMID:35693790 PubMed Central PMC9175567.
  68. Savulescu, C, Krizova, P, Valentiner-Branth, P, Ladhani, S, Rinta-Kokko, H, Levy, C et al.. Effectiveness of 10 and 13-valent pneumococcal conjugate vaccines against invasive pneumococcal disease in European children: SpIDnet observational multicentre study. Vaccine. 2022;40 (29):3963-3974. doi: 10.1016/j.vaccine.2022.05.011. PubMed PMID:35637067 .
  69. Schober, SJ, Hallmen, E, Reßle, F, Gassmann, H, Prexler, C, Wawer, A et al.. No Improvement of Survival for Alveolar Rhabdomyosarcoma Patients After HLA-Matched Versus -Mismatched Allogeneic Hematopoietic Stem Cell Transplantation Compared to Standard-of-Care Therapy. Front Oncol. 2022;12 :878367. doi: 10.3389/fonc.2022.878367. PubMed PMID:35619911 PubMed Central PMC9127413.
  70. Lehtimaki, M, Paunonen, L, Linne, ML. Accelerating Neural ODEs Using Model Order Reduction. IEEE Trans Neural Netw Learn Syst. 2022;PP :. doi: 10.1109/TNNLS.2022.3175757. PubMed PMID:35617183 .
  71. Paavola, S, Kurppa, K, Huhtala, H, Saavalainen, P, Lindfors, K, Kaukinen, K et al.. Coeliac disease re-screening among once seronegative at-risk relatives: A long-term follow-up study. United European Gastroenterol J. 2022;10 (6):585-593. doi: 10.1002/ueg2.12255. PubMed PMID:35611878 PubMed Central PMC9278577.
  72. Korppi, M, Heikkilä, P, Palmu, S, Huhtala, H, Csonka, P. Antibiotic prescribing for children with upper respiratory tract infection: a Finnish nationwide 7-year observational study. Eur J Pediatr. 2022;181 (8):2981-2990. doi: 10.1007/s00431-022-04512-w. PubMed PMID:35606593 PubMed Central PMC9126572.
  73. Das, R, Kabir, MF, Ashorn, P, Simon, J, Chisti, MJ, Ahmed, T et al.. Maternal Underweight and Its Association with Composite Index of Anthropometric Failure among Children under Two Years of Age with Diarrhea in Bangladesh. Nutrients. 2022;14 (9):. doi: 10.3390/nu14091935. PubMed PMID:35565901 PubMed Central PMC9105738.
  74. Oksa, L, Mäkinen, A, Nikkilä, A, Hyvärinen, N, Laukkanen, S, Rokka, A et al.. Arginine Methyltransferase PRMT7 Deregulates Expression of RUNX1 Target Genes in T-Cell Acute Lymphoblastic Leukemia. Cancers (Basel). 2022;14 (9):. doi: 10.3390/cancers14092169. PubMed PMID:35565298 PubMed Central PMC9101393.
  75. Laukkanen, S, Veloso, A, Yan, C, Oksa, L, Alpert, EJ, Do, D et al.. Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia. Blood. 2022;140 (17):1891-1906. doi: 10.1182/blood.2021015106. PubMed PMID:35544598 PubMed Central PMC10082361.
  76. Lähdepuro, A, Lahti-Pulkkinen, M, Pyhälä, R, Tuovinen, S, Lahti, J, Heinonen, K et al.. Positive maternal mental health during pregnancy and mental and behavioral disorders in children: A prospective pregnancy cohort study. J Child Psychol Psychiatry. 2023;64 (5):807-816. doi: 10.1111/jcpp.13625. PubMed PMID:35524467 .
  77. Sievänen, H, Palmu, S, Kari, J, Soukka, H, Lähteenmäki, P, Eskola, V et al.. Incidence of Traumatic Lumbar Punctures in Neonates and Infants. Am J Perinatol. 2022; :. doi: 10.1055/a-1845-2335. PubMed PMID:35523412 .
  78. Mäntynen, E, Palmu, S, Heikkilä, P. Families’ costs form a considerable part of total costs in bronchiolitis care. Health Sci Rep. 2022;5 (3):e593. doi: 10.1002/hsr2.593. PubMed PMID:35509378 PubMed Central PMC9059178.
  79. Huvinen, E, Lahti, J, Klemetti, MM, Bergman, PH, Räikkönen, K, Orho-Melander, M et al.. Genetic risk of type 2 diabetes modifies the effects of a lifestyle intervention aimed at the prevention of gestational and postpartum diabetes. Diabetologia. 2022;65 (8):1291-1301. doi: 10.1007/s00125-022-05712-7. PubMed PMID:35501401 PubMed Central PMC9283155.
  80. Välikangas, T, Lietzén, N, Jaakkola, MK, Krogvold, L, Eike, MC, Kallionpää, H et al.. Pancreas Whole Tissue Transcriptomics Highlights the Role of the Exocrine Pancreas in Patients With Recently Diagnosed Type 1 Diabetes. Front Endocrinol (Lausanne). 2022;13 :861985. doi: 10.3389/fendo.2022.861985. PubMed PMID:35498413 PubMed Central PMC9044038.
  81. Långström, S, Huurre, A, Kari, J, Lohi, O, Sievänen, H, Palmu, S et al.. Bioimpedance spinal needle provides high success and low complication rate in lumbar punctures of pediatric patients with acute lymphoblastic leukemia. Sci Rep. 2022;12 (1):6799. doi: 10.1038/s41598-022-10915-4. PubMed PMID:35474331 PubMed Central PMC9042945.
  82. Linne, ML, Aćimović, J, Saudargiene, A, Manninen, T. Neuron-Glia Interactions and Brain Circuits. Adv Exp Med Biol. 2022;1359 :87-103. doi: 10.1007/978-3-030-89439-9_4. PubMed PMID:35471536 .
  83. Sievänen, H, Lähteenmäki, P, Kari, J, Halonen, S, Soukka, H, Eskola, V et al.. Traumatic lumbar punctures in diagnostic and intrathecal treatment punctures of pediatric hemato-oncology patients. Pediatr Hematol Oncol. 2022;39 (8):697-706. doi: 10.1080/08880018.2022.2062501. PubMed PMID:35465834 .
  84. Soininen, L, Roslund, MI, Nurminen, N, Puhakka, R, Laitinen, OH, Hyöty, H et al.. Indoor green wall affects health-associated commensal skin microbiota and enhances immune regulation: a randomized trial among urban office workers. Sci Rep. 2022;12 (1):6518. doi: 10.1038/s41598-022-10432-4. PubMed PMID:35444249 PubMed Central PMC9021224.
  85. Dijkstra, DJ, Lokki, AI, Gierman, LM, Borggreven, NV, van der Keur, C, Eikmans, M et al.. Circulating Levels of Anti-C1q and Anti-Factor H Autoantibodies and Their Targets in Normal Pregnancy and Preeclampsia. Front Immunol. 2022;13 :842451. doi: 10.3389/fimmu.2022.842451. PubMed PMID:35432365 PubMed Central PMC9009242.
  86. Kaltiala, R, Holttinen, T, Ellonen, N. Sex offending among adolescents and young men with history of psychiatric inpatient care in adolescence. Crim Behav Ment Health. 2022;32 (2):87-99. doi: 10.1002/cbm.2236. PubMed PMID:35419915 PubMed Central PMC9325519.
  87. Hård Af Segerstad, EM, Liu, X, Uusitalo, U, Agardh, D, Andrén Aronsson, C, TEDDY Study Group et al.. Sources of dietary gluten in the first 2 years of life and associations with celiac disease autoimmunity and celiac disease in Swedish genetically predisposed children: The Environmental Determinants of Diabetes in the Young (TEDDY) study. Am J Clin Nutr. 2022;116 (2):394-403. doi: 10.1093/ajcn/nqac086. PubMed PMID:35394004 PubMed Central PMC9348971.
  88. Bellenguez, C, Küçükali, F, Jansen, IE, Kleineidam, L, Moreno-Grau, S, Amin, N et al.. New insights into the genetic etiology of Alzheimer’s disease and related dementias. Nat Genet. 2022;54 (4):412-436. doi: 10.1038/s41588-022-01024-z. PubMed PMID:35379992 PubMed Central PMC9005347.
  89. Repo, M, Pessi, J, Wirtanen, E, Hiltunen, P, Huhtala, H, Kivelä, L et al.. Frequency and clinical significance of histologic upper gastrointestinal tract findings in children with inflammatory bowel disease. Scand J Gastroenterol. 2022;57 (9):1046-1050. doi: 10.1080/00365521.2022.2057197. PubMed PMID:35361047 .
  90. Csonka, P, Korppi, M. Electronic health record databases provide a platform for intervention studies. Acta Paediatr. 2022;111 (6):1104-1106. doi: 10.1111/apa.16329. PubMed PMID:35332573 .
  91. Haskell, MJ, Maleta, K, Arnold, CD, Jorgensen, JM, Fan, YM, Ashorn, U et al.. Provision of Small-Quantity Lipid-Based Nutrient Supplements Increases Plasma Selenium Concentration in Pregnant Women in Malawi: A Secondary Outcome of a Randomized Controlled Trial. Curr Dev Nutr. 2022;6 (3):nzac013. doi: 10.1093/cdn/nzac013. PubMed PMID:35317414 PubMed Central PMC8929992.
  92. Batool, R, Yousafzai, MT, Qureshi, S, Ali, M, Sadaf, T, Mehmood, J et al.. Corrigendum to “Effectiveness of typhoid conjugate vaccine against culture-confirmed typhoid in a peri-urban setting in Karachi: A case-control study”. [Vaccine 39 (2021) 5858-5865]. Vaccine. 2022;40 (16):2471. doi: 10.1016/j.vaccine.2022.03.019. PubMed PMID:35307231 .
  93. Törn, C, Liu, X, Onengut-Gumuscu, S, Counts, KM, Moreno, JL, Remedios, CL et al.. Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study. Sci Rep. 2022;12 (1):4516. doi: 10.1038/s41598-022-08058-7. PubMed PMID:35296692 PubMed Central PMC8927592.
  94. Rannikko, J, Tamminen, P, Hellsten, R, Nuorti, JP, Syrjänen, J. Effectiveness of COVID-19 digital proximity tracing app in Finland. Clin Microbiol Infect. 2022;28 (6):903-904. doi: 10.1016/j.cmi.2022.03.002. PubMed PMID:35283308 PubMed Central PMC8913429.
  95. Korppi, M, Heikkilä, P, Palmu, S, Huhtala, H, Csonka, P. Antibiotic prescriptions for children with lower respiratory tract infections fell from 2014 to 2020, but misuse was still an issue. Acta Paediatr. 2022;111 (6):1230-1237. doi: 10.1111/apa.16323. PubMed PMID:35266193 .
  96. Virkkula, A, Kivela, L, Hiltunen, P, Sotka, A, Huhtala, H, Kurppa, K et al.. Prevalence and Clinical Significance of Helicobacter Pylori-negative Chronic Gastritis in Children. J Pediatr Gastroenterol Nutr. 2022;74 (5):949-955. doi: 10.1097/MPG.0000000000003440. PubMed PMID:35258500 .
  97. Jääskeläinen, T, Kärkkäinen, O, Heinonen, S, Hanhineva, K, Laivuori, H. No association in maternal serum levels of TMAO and its precursors in pre-eclampsia and in non-complicated pregnancies. Pregnancy Hypertens. 2022;28 :74-80. doi: 10.1016/j.preghy.2022.02.008. PubMed PMID:35247822 .
  98. Li, Z, Veijola, R, Koski, E, Anand, V, Martin, F, Waugh, K et al.. Childhood Height Growth Rate Association With the Risk of Islet Autoimmunity and Development of Type 1 Diabetes. J Clin Endocrinol Metab. 2022;107 (6):1520-1528. doi: 10.1210/clinem/dgac121. PubMed PMID:35244713 PubMed Central PMC9113806.
  99. Akseer, N, Keats, EC, Thurairajah, P, Cousens, S, Bétran, AP, Oaks, BM et al.. Characteristics and birth outcomes of pregnant adolescents compared to older women: An analysis of individual level data from 140,000 mothers from 20 RCTs. EClinicalMedicine. 2022;45 :101309. doi: 10.1016/j.eclinm.2022.101309. PubMed PMID:35243274 PubMed Central PMC8885463.
  100. Jääskeläinen, T, Kivelä, A, Renlund, M, Heinonen, S, Aittasalo, M, Laivuori, H et al.. Protocol: A randomized controlled trial to assess effectiveness of a 12-month lifestyle intervention to reduce cardiovascular disease risk in families ten years after pre-eclampsia (FINNCARE). Prev Med Rep. 2022;26 :101731. doi: 10.1016/j.pmedr.2022.101731. PubMed PMID:35242500 PubMed Central PMC8861388.
  101. Melander, K, Kortteisto, T, Hermanson, E, Kaltiala, R, Mäki-Kokkila, K, Kaila, M et al.. The perceptions of different professionals on school absenteeism and the role of school health care: A focus group study conducted in Finland. PLoS One. 2022;17 (2):e0264259. doi: 10.1371/journal.pone.0264259. PubMed PMID:35226678 PubMed Central PMC8884500.
  102. Pervjakova, N, Moen, GH, Borges, MC, Ferreira, T, Cook, JP, Allard, C et al.. Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes. Hum Mol Genet. 2022;31 (19):3377-3391. doi: 10.1093/hmg/ddac050. PubMed PMID:35220425 PubMed Central PMC9523562.
  103. Tamlander, M, Mars, N, Pirinen, M, FinnGen, Widén, E, Ripatti, S et al.. Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes. Commun Biol. 2022;5 (1):158. doi: 10.1038/s42003-021-02996-0. PubMed PMID:35197564 PubMed Central PMC8866413.
  104. Choudhary, MK, Penninkangas, RM, Eräranta, A, Niemelä, O, Mangani, C, Maleta, K et al.. Posture-Related Differences in Cardiovascular Function Between Young Men and Women: Study of Noninvasive Hemodynamics in Rural Malawi. J Am Heart Assoc. 2022;11 (5):e022979. doi: 10.1161/JAHA.121.022979. PubMed PMID:35195013 PubMed Central PMC9075090.
  105. Ferrat, LA, Vehik, K, Sharp, SA, Lernmark, Å, Rewers, MJ, She, JX et al.. Author Correction: A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat Med. 2022;28 (3):599. doi: 10.1038/s41591-021-01631-z. PubMed PMID:35165454 .
  106. El-Amin, S, Kinnunen, JM, Rimpelä, A. Adolescents’ Perceptions of Harmfulness of Tobacco and Tobacco-like Products in Finland. Int J Environ Res Public Health. 2022;19 (3):. doi: 10.3390/ijerph19031485. PubMed PMID:35162508 PubMed Central PMC8834861.
  107. Smith, JW, Matchado, AJ, Wu, LS, Arnold, CD, Burke, SM, Maleta, KM et al.. Longitudinal Assessment of Prenatal, Perinatal, and Early-Life Aflatoxin B1 Exposure in 828 Mother-Child Dyads from Bangladesh and Malawi. Curr Dev Nutr. 2022;6 (2):nzab153. doi: 10.1093/cdn/nzab153. PubMed PMID:35155983 PubMed Central PMC8829025.
  108. Kortekangas, E, Fan, YM, Chaima, D, Lehto, KM, Malamba-Banda, C, Matchado, A et al.. Associations between Gut Microbiota and Intestinal Inflammation, Permeability and Damage in Young Malawian Children. J Trop Pediatr. 2022;68 (2):. doi: 10.1093/tropej/fmac012. PubMed PMID:35149871 PubMed Central PMC8846364.
  109. Palmu, S, Heikkilä, P, Kivistö, JE, Poutanen, R, Korppi, M, Renko, M et al.. Cough medicine prescriptions for children were significantly reduced by a systematic intervention that reinforced national recommendations. Acta Paediatr. 2022;111 (6):1248-1249. doi: 10.1111/apa.16284. PubMed PMID:35143072 PubMed Central PMC9305792.
  110. Suomi, T, Kalim, UU, Rasool, O, Laiho, A, Kallionpää, H, Vähä-Mäkilä, M et al.. Type 1 Diabetes in Children With Genetic Risk May Be Predicted Very Early With a Blood miRNA. Diabetes Care. 2022;45 (4):e77-e79. doi: 10.2337/dc21-2120. PubMed PMID:35134118 PubMed Central PMC9016735.
  111. Liu, Z, Ashorn, U, Chingwanda, C, Maleta, K, Hallamaa, L, Matchado, A et al.. Provision of small-quantity lipid-based nutrient supplements does not improve intestinal health among rural Malawian children. Matern Child Nutr. 2022;18 (3):e13331. doi: 10.1111/mcn.13331. PubMed PMID:35128820 PubMed Central PMC9218311.
  112. Dieckmann, L, Cruceanu, C, Lahti-Pulkkinen, M, Lahti, J, Kvist, T, Laivuori, H et al.. Reliability of a novel approach for reference-based cell type estimation in human placental DNA methylation studies. Cell Mol Life Sci. 2022;79 (2):115. doi: 10.1007/s00018-021-04091-3. PubMed PMID:35113241 PubMed Central PMC8813756.
  113. Kvist, T, Sammallahti, S, Lahti-Pulkkinen, M, Cruceanu, C, Czamara, D, Dieckmann, L et al.. Cohort profile: InTraUterine sampling in early pregnancy (ITU), a prospective pregnancy cohort study in Finland: study design and baseline characteristics. BMJ Open. 2022;12 (1):e049231. doi: 10.1136/bmjopen-2021-049231. PubMed PMID:35105615 PubMed Central PMC8804635.
  114. Raitasalo, K, Bye, EK, Pisinger, C, Scheffels, J, Tokle, R, Kinnunen, JM et al.. Single, Dual, and Triple Use of Cigarettes, e-Cigarettes, and Snus among Adolescents in the Nordic Countries. Int J Environ Res Public Health. 2022;19 (2):. doi: 10.3390/ijerph19020683. PubMed PMID:35055504 PubMed Central PMC8775390.
  115. Jacobsen, LM, Vehik, K, Veijola, R, Warncke, K, Toppari, J, Steck, AK et al.. Heterogeneity of DKA Incidence and Age-Specific Clinical Characteristics in Children Diagnosed With Type 1 Diabetes in the TEDDY Study. Diabetes Care. 2022;45 (3):624-633. doi: 10.2337/dc21-0422. PubMed PMID:35043162 PubMed Central PMC8918232.
  116. Girchenko, P, Robinson, R, Rantalainen, VJ, Lahti-Pulkkinen, M, Heinonen-Tuomaala, K, Lemola, S et al.. Maternal postpartum depressive symptoms partially mediate the association between preterm birth and mental and behavioral disorders in children. Sci Rep. 2022;12 (1):947. doi: 10.1038/s41598-022-04990-w. PubMed PMID:35042942 PubMed Central PMC8766431.
  117. Buchacher, T, Honkimaa, A, Välikangas, T, Lietzén, N, Hirvonen, MK, Laiho, JE et al.. Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells. iScience. 2022;25 (1):103653. doi: 10.1016/j.isci.2021.103653. PubMed PMID:35024587 PubMed Central PMC8728469.
  118. Colston, JM, Zaitchik, BF, Badr, HS, Burnett, E, Ali, SA, Rayamajhi, A et al.. Associations Between Eight Earth Observation-Derived Climate Variables and Enteropathogen Infection: An Independent Participant Data Meta-Analysis of Surveillance Studies With Broad Spectrum Nucleic Acid Diagnostics. Geohealth. 2022;6 (1):e2021GH000452. doi: 10.1029/2021GH000452. PubMed PMID:35024531 PubMed Central PMC8729196.
  119. Melin, J, Lynch, KF, Lundgren, M, Aronsson, CA, Larsson, HE, Johnson, SB et al.. Is staff consistency important to parents’ satisfaction in a longitudinal study of children at risk for type 1 diabetes: the TEDDY study. BMC Endocr Disord. 2022;22 (1):19. doi: 10.1186/s12902-021-00929-w. PubMed PMID:35012530 PubMed Central PMC8744326.
  120. Gomes, F, Ashorn, P, Askari, S, Belizan, JM, Boy, E, Cormick, G et al.. Calcium supplementation for the prevention of hypertensive disorders of pregnancy: current evidence and programmatic considerations. Ann N Y Acad Sci. 2022;1510 (1):52-67. doi: 10.1111/nyas.14733. PubMed PMID:35000200 PubMed Central PMC9306576.
  121. Kinnunen, JM, Paakkari, L, Rimpelä, AH, Kulmala, M, Richter, M, Kuipers, MAG et al.. The role of health literacy in the association between academic performance and substance use. Eur J Public Health. 2022;32 (2):182-187. doi: 10.1093/eurpub/ckab213. PubMed PMID:34986239 PubMed Central PMC8975541.
  122. Lachman, A, Jordaan, ER, Stern, M, Donald, KA, Hoffman, N, Lake, MT et al.. The Shared Pleasure Paradigm: A study in an observational birth cohort in South Africa. Arch Womens Ment Health. 2022;25 (1):227-235. doi: 10.1007/s00737-021-01199-0. PubMed PMID:34985581 PubMed Central PMC8784495.
  123. Martinez, MM, Spiliopoulos, L, Salami, F, Agardh, D, Toppari, J, Lernmark, Å et al.. Heterogeneity of beta-cell function in subjects with multiple islet autoantibodies in the TEDDY family prevention study – TEFA. Clin Diabetes Endocrinol. 2022;7 (1):23. doi: 10.1186/s40842-021-00135-6. PubMed PMID:34983671 PubMed Central PMC8728995.
  124. Korhonen, P, Tihtonen, K, Isojärvi, J, Ojala, R, Ashorn, U, Ashorn, P et al.. Calcium supplementation during pregnancy and long-term offspring outcome: a systematic literature review and meta-analysis. Ann N Y Acad Sci. 2022;1510 (1):36-51. doi: 10.1111/nyas.14729. PubMed PMID:34978718 PubMed Central PMC9304138.
  125. Hanquet, G, Krizova, P, Dalby, T, Ladhani, SN, Nuorti, JP, Danis, K et al.. Serotype Replacement after Introduction of 10-Valent and 13-Valent Pneumococcal Conjugate Vaccines in 10 Countries, Europe. Emerg Infect Dis. 2022;28 (1):137-138. doi: 10.3201/eid2801.210734. PubMed PMID:34932457 PubMed Central PMC8714201.
  126. Ervaala, A, Laivuori, H, Gissler, M, Kere, J, Kivinen, K, Pouta, A et al.. Characteristics of preeclampsia in donor cell gestations. Pregnancy Hypertens. 2022;27 :59-61. doi: 10.1016/j.preghy.2021.12.005. PubMed PMID:34929557 .
  127. Kekki, M, Tihtonen, K, Salonen, A, Koukkula, T, Gissler, M, Laivuori, H et al.. Severe birth injuries in neonates and associated risk factors for injury in mothers with different types of diabetes in Finland. Int J Gynaecol Obstet. 2022;159 (1):195-203. doi: 10.1002/ijgo.14073. PubMed PMID:34927725 PubMed Central PMC9545198.
  128. Csonka, P, Heikkilä, P, Koskela, S, Palmu, S, Lajunen, N, Riihijärvi, S et al.. Cough and cold medicine prescription rates can be significantly reduced by active intervention. Eur J Pediatr. 2022;181 (4):1531-1539. doi: 10.1007/s00431-021-04344-0. PubMed PMID:34913111 PubMed Central PMC8673918.
  129. González-Rodríguez, MI, Nurminen, N, Kummola, L, Laitinen, OH, Oikarinen, S, Parajuli, A et al.. Effect of inactivated nature-derived microbial composition on mouse immune system. Immun Inflamm Dis. 2022;10 (3):e579. doi: 10.1002/iid3.579. PubMed PMID:34873877 PubMed Central PMC8926502.
  130. Marabita, F, James, T, Karhu, A, Virtanen, H, Kettunen, K, Stenlund, H et al.. Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health. Cell Syst. 2022;13 (3):241-255.e7. doi: 10.1016/j.cels.2021.11.001. PubMed PMID:34856119 .
  131. Tyrmi, JS, Arffman, RK, Pujol-Gualdo, N, Kurra, V, Morin-Papunen, L, Sliz, E et al.. Leveraging Northern European population history: novel low-frequency variants for polycystic ovary syndrome. Hum Reprod. 2022;37 (2):352-365. doi: 10.1093/humrep/deab250. PubMed PMID:34791234 PubMed Central PMC8804330.
  132. Tihtonen, K, Korhonen, P, Isojärvi, J, Ojala, R, Ashorn, U, Ashorn, P et al.. Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis. Ann N Y Acad Sci. 2022;1509 (1):23-36. doi: 10.1111/nyas.14705. PubMed PMID:34780069 PubMed Central PMC9298950.
  133. Ventelä, J, Nikkilä, A, Jukkola, A, Lohi, O. Incidence and outcomes of cancer in 16- to 17-year-old adolescents. Acta Paediatr. 2022;111 (2):442-444. doi: 10.1111/apa.16161. PubMed PMID:34689375 PubMed Central PMC9299452.
  134. Adu-Afarwuah, S, Arnold, CD, Lartey, A, Okronipa, H, Maleta, K, Ashorn, P et al.. Small-Quantity Lipid-Based Nutrient Supplements Increase Infants’ Plasma Essential Fatty Acid Levels in Ghana and Malawi: A Secondary Outcome Analysis of the iLiNS-DYAD Randomized Trials. J Nutr. 2022;152 (1):286-301. doi: 10.1093/jn/nxab329. PubMed PMID:34543432 .
  135. Videman, K, Hallamaa, L, Heimonen, O, Mangani, C, Luntamo, M, Maleta, K et al.. Child growth and neurodevelopment after maternal antenatal antibiotic treatment. Arch Dis Child. 2022;107 (4):323-328. doi: 10.1136/archdischild-2021-322043. PubMed PMID:34479861 PubMed Central PMC8938655.
  136. Kakko, K, Keskinen, P, Pihlakoski, L, Salmelin, R, Puura, K. In search of measures to improve the detection of increased cardiometabolic risk in children using second-generation antipsychotic medications. Nord J Psychiatry. 2022;76 (4):316-322. doi: 10.1080/08039488.2021.1968489. PubMed PMID:34431750 .
  137. Holttinen, T, Pirkola, S, Rimpelä, M, Kaltiala, R. Factors behind a remarkable increase in adolescent psychiatric inpatient treatment between 1980 and 2010 – a nationwide register study. Nord J Psychiatry. 2022;76 (2):120-128. doi: 10.1080/08039488.2021.1939780. PubMed PMID:34185597 .
  138. Schwarz, TF, Johnson, C, Grigat, C, Apter, D, Csonka, P, Lindblad, N et al.. Three Dose Levels of a Maternal Respiratory Syncytial Virus Vaccine Candidate Are Well Tolerated and Immunogenic in a Randomized Trial in Nonpregnant Women. J Infect Dis. 2022;225 (12):2067-2076. doi: 10.1093/infdis/jiab317. PubMed PMID:34146100 PubMed Central PMC9200160.
  139. Keats, EC, Akseer, N, Thurairajah, P, Cousens, S, Bhutta, ZA, Global Young Women’s Nutrition Investigators’ Group et al.. Multiple-micronutrient supplementation in pregnant adolescents in low- and middle-income countries: a systematic review and a meta-analysis of individual participant data. Nutr Rev. 2022;80 (2):141-156. doi: 10.1093/nutrit/nuab004. PubMed PMID:33846729 PubMed Central PMC8754251.
  140. Hoppu, S, Hannola, K, Mennander, S, Huhtala, H, Rissanen, M, Tulensalo, E et al.. Routine Bedside Use of Obstetric Early Warning System in the Postnatal Ward to Identify Maternal Morbidity Among High-Risk Women. J Patient Saf. 2022;18 (1):e338-e342. doi: 10.1097/PTS.0000000000000766. PubMed PMID:32925568 .

Search PubMed

2021

  1. Kivelä, L, Kurppa, K. Letter to the Editor for the article “20-year follow-up study of celiac patients identified in a mass school screening: compliance to gluten-free diet and autoimmunity”. J Pediatr Gastroenterol Nutr. 2022;74 (4):e101. doi: 10.1097/MPG.0000000000003351. PubMed PMID:35703950 .
  2. Buchacher, T, Honkimaa, A, Välikangas, T, Lietzén, N, Hirvonen, MK, Laiho, JE et al.. Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells. iScience. 2022;25 (1):103653. doi: 10.1016/j.isci.2021.103653. PubMed PMID:35024587 PubMed Central PMC8728469.
  3. Polkowska, A, Räsänen, S, Nuorti, P, Maunula, L, Jalava, K. Assessment of Food and Waterborne Viral Outbreaks by Using Field Epidemiologic, Modern Laboratory and Statistical Methods-Lessons Learnt from Seven Major Norovirus Outbreaks in Finland. Pathogens. 2021;10 (12):. doi: 10.3390/pathogens10121624. PubMed PMID:34959579 PubMed Central PMC8707936.
  4. Bopegamage, S, Berakova, K, Gomocak, P, Baksova, R, Galama, J, Hyoty, H et al.. Primary Site of Coxsackievirus B Replication in the Small Intestines: No Proof of Peyer’s Patches Involvement. Microorganisms. 2021;9 (12):. doi: 10.3390/microorganisms9122600. PubMed PMID:34946201 PubMed Central PMC8709031.
  5. Sinha, B, Sommerfelt, H, Ashorn, P, Mazumder, S, More, D, Taneja, S et al.. Effect of Community-Initiated Kangaroo Mother Care on Fecal Biomarkers of Gut Function in Low Birth Weight Infants in North India: A Randomized Clinical Trial. Am J Trop Med Hyg. 2021;106 (3):945-952. doi: 10.4269/ajtmh.21-0877. PubMed PMID:34929667 PubMed Central PMC8922485.
  6. Ervaala, A, Laivuori, H, Gissler, M, Kere, J, Kivinen, K, Pouta, A et al.. Characteristics of preeclampsia in donor cell gestations. Pregnancy Hypertens. 2022;27 :59-61. doi: 10.1016/j.preghy.2021.12.005. PubMed PMID:34929557 .
  7. Antibiotics for Children With Diarrhea (ABCD) Study Group, Ahmed, T, Chisti, MJ, Rahman, MW, Alam, T, Ahmed, D et al.. Effect of 3 Days of Oral Azithromycin on Young Children With Acute Diarrhea in Low-Resource Settings: A Randomized Clinical Trial. JAMA Netw Open. 2021;4 (12):e2136726. doi: 10.1001/jamanetworkopen.2021.36726. PubMed PMID:34913980 PubMed Central PMC8678692.
  8. Csonka, P, Heikkilä, P, Koskela, S, Palmu, S, Lajunen, N, Riihijärvi, S et al.. Cough and cold medicine prescription rates can be significantly reduced by active intervention. Eur J Pediatr. 2022;181 (4):1531-1539. doi: 10.1007/s00431-021-04344-0. PubMed PMID:34913111 PubMed Central PMC8673918.
  9. Airaksinen, L, Cerqueira, JX, Huhtala, H, Saavalainen, P, Yohannes, DA, Mäki, M et al.. Dissecting the contribution of single nucleotide polymorphisms in CCR9 and CCL25 genomic regions to the celiac disease phenotype. J Transl Autoimmun. 2021;4 :100128. doi: 10.1016/j.jtauto.2021.100128. PubMed PMID:34901814 PubMed Central PMC8640869.
  10. Kivimäki, HM, Ståhl, TP, Joronen, KM, Rimpelä, AH. Parents’ Participation in School Health Examinations for Their Adolescent Children in Finland. J Sch Nurs. 2021; :10598405211058841. doi: 10.1177/10598405211058841. PubMed PMID:34894843 .
  11. Rimpelä, A, Lindfors, P, Kinnunen, JM, Myöhänen, A, Hotulainen, R, Koivuhovi, S et al.. The Way of Distance Teaching Is Related to Adolescent Students’ Health and Loneliness during the School Closure in Finland. Int J Environ Res Public Health. 2021;18 (23):. doi: 10.3390/ijerph182312377. PubMed PMID:34886104 PubMed Central PMC8657008.
  12. González-Rodríguez, MI, Nurminen, N, Kummola, L, Laitinen, OH, Oikarinen, S, Parajuli, A et al.. Effect of inactivated nature-derived microbial composition on mouse immune system. Immun Inflamm Dis. 2022;10 (3):e579. doi: 10.1002/iid3.579. PubMed PMID:34873877 PubMed Central PMC8926502.
  13. Marabita, F, James, T, Karhu, A, Virtanen, H, Kettunen, K, Stenlund, H et al.. Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health. Cell Syst. 2022;13 (3):241-255.e7. doi: 10.1016/j.cels.2021.11.001. PubMed PMID:34856119 .
  14. Koivu, AM, Hunter, PJ, Näsänen-Gilmore, P, Muthiani, Y, Isojärvi, J, Pörtfors, P et al.. Modular literature review: a novel systematic search and review method to support priority setting in health policy and practice. BMC Med Res Methodol. 2021;21 (1):268. doi: 10.1186/s12874-021-01463-y. PubMed PMID:34837952 PubMed Central PMC8627616.
  15. Brænne, I, Onengut-Gumuscu, S, Chen, R, Manichaikul, AW, Rich, SS, Chen, WM et al.. Dynamic changes in immune gene co-expression networks predict development of type 1 diabetes. Sci Rep. 2021;11 (1):22651. doi: 10.1038/s41598-021-01840-z. PubMed PMID:34811390 PubMed Central PMC8609030.
  16. Blangis, F, Allali, S, Cohen, JF, Vabres, N, Adamsbaum, C, Rey-Salmon, C et al.. Variations in Guidelines for Diagnosis of Child Physical Abuse in High-Income Countries: A Systematic Review. JAMA Netw Open. 2021;4 (11):e2129068. doi: 10.1001/jamanetworkopen.2021.29068. PubMed PMID:34787659 PubMed Central PMC8600386.
  17. Tihtonen, K, Korhonen, P, Isojärvi, J, Ojala, R, Ashorn, U, Ashorn, P et al.. Calcium supplementation during pregnancy and maternal and offspring bone health: a systematic review and meta-analysis. Ann N Y Acad Sci. 2022;1509 (1):23-36. doi: 10.1111/nyas.14705. PubMed PMID:34780069 PubMed Central PMC9298950.
  18. Ventelä, J, Nikkilä, A, Jukkola, A, Lohi, O. Incidence and outcomes of cancer in 16- to 17-year-old adolescents. Acta Paediatr. 2022;111 (2):442-444. doi: 10.1111/apa.16161. PubMed PMID:34689375 PubMed Central PMC9299452.
  19. Francis, MR, Nuorti, JP, Lumme-Sandt, K, Kompithra, RZ, Balraj, V, Kang, G et al.. Vaccination coverage and the factors influencing routine childhood vaccination uptake among communities experiencing disadvantage in Vellore, southern India: a mixed-methods study. BMC Public Health. 2021;21 (1):1807. doi: 10.1186/s12889-021-11881-8. PubMed PMID:34620139 PubMed Central PMC8499461.
  20. Sulkanen, E, Repo, M, Huhtala, H, Hiltunen, P, Kurppa, K. Impact of diagnostic delay to the clinical presentation and associated factors in pediatric inflammatory bowel disease: a retrospective study. BMC Gastroenterol. 2021;21 (1):364. doi: 10.1186/s12876-021-01938-8. PubMed PMID:34620103 PubMed Central PMC8495911.
  21. Andrén Aronsson, C, Liu, X, Norris, JM, Uusitalo, U, Butterworth, MD, Koletzko, S et al.. 25(OH)D Levels in Infancy Is Associated With Celiac Disease Autoimmunity in At-Risk Children: A Case-Control Study. Front Nutr. 2021;8 :720041. doi: 10.3389/fnut.2021.720041. PubMed PMID:34604278 PubMed Central PMC8479793.
  22. Dewey, KG, Wessells, KR, Arnold, CD, Prado, EL, Abbeddou, S, Adu-Afarwuah, S et al.. Characteristics that modify the effect of small-quantity lipid-based nutrient supplementation on child growth: an individual participant data meta-analysis of randomized controlled trials. Am J Clin Nutr. 2021;114 (Suppl 1):15S-42S. doi: 10.1093/ajcn/nqab278. PubMed PMID:34590672 PubMed Central PMC8560308.
  23. Prado, EL, Arnold, CD, Wessells, KR, Stewart, CP, Abbeddou, S, Adu-Afarwuah, S et al.. Small-quantity lipid-based nutrient supplements for children age 6-24 months: a systematic review and individual participant data meta-analysis of effects on developmental outcomes and effect modifiers. Am J Clin Nutr. 2021;114 (Suppl 1):43S-67S. doi: 10.1093/ajcn/nqab277. PubMed PMID:34590116 PubMed Central PMC8560311.
  24. Wessells, KR, Arnold, CD, Stewart, CP, Prado, EL, Abbeddou, S, Adu-Afarwuah, S et al.. Characteristics that modify the effect of small-quantity lipid-based nutrient supplementation on child anemia and micronutrient status: an individual participant data meta-analysis of randomized controlled trials. Am J Clin Nutr. 2021;114 (Suppl 1):68S-94S. doi: 10.1093/ajcn/nqab276. PubMed PMID:34590114 PubMed Central PMC8560313.
  25. Monangi, N, Xu, H, Khanam, R, Khan, W, Deb, S, Pervin, J et al.. Association of maternal prenatal selenium concentration and preterm birth: a multicountry meta-analysis. BMJ Glob Health. 2021;6 (9):. doi: 10.1136/bmjgh-2021-005856. PubMed PMID:34518202 PubMed Central PMC8438754.
  26. Paavola, S, Kaukinen, K, Kurppa, K. Editorial: coeliac disease-it’s a family affair. Authors’ reply. Aliment Pharmacol Ther. 2021;54 (7):969. doi: 10.1111/apt.16584. PubMed PMID:34506653 .
  27. Stone, VM, Butrym, M, Hankaniemi, MM, Sioofy-Khojine, AB, Hytönen, VP, Hyöty, H et al.. Coxsackievirus B Vaccines Prevent Infection-Accelerated Diabetes in NOD Mice and Have No Disease-Inducing Effect. Diabetes. 2021;70 (12):2871-2878. doi: 10.2337/db21-0193. PubMed PMID:34497136 PubMed Central PMC8660981.
  28. Nevalainen, J, Datta, S, Toppari, J, Ilonen, J, Hyöty, H, Veijola, R et al.. Frailty modeling under a selective sampling protocol: an application to type 1 diabetes related autoantibodies. Stat Med. 2021;40 (28):6410-6420. doi: 10.1002/sim.9190. PubMed PMID:34496070 .
  29. Videman, K, Hallamaa, L, Heimonen, O, Mangani, C, Luntamo, M, Maleta, K et al.. Child growth and neurodevelopment after maternal antenatal antibiotic treatment. Arch Dis Child. 2022;107 (4):323-328. doi: 10.1136/archdischild-2021-322043. PubMed PMID:34479861 PubMed Central PMC8938655.
  30. Batool, R, Tahir Yousafzai, M, Qureshi, S, Ali, M, Sadaf, T, Mehmood, J et al.. Effectiveness of typhoid conjugate vaccine against culture-confirmed typhoid in a peri-urban setting in Karachi: A case-control study. Vaccine. 2021;39 (40):5858-5865. doi: 10.1016/j.vaccine.2021.08.051. PubMed PMID:34465474 .
  31. Czamara, D, Dieckmann, L, Röh, S, Kraemer, S, Rancourt, RC, Sammallahti, S et al.. Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation. Clin Epigenetics. 2021;13 (1):165. doi: 10.1186/s13148-021-01153-y. PubMed PMID:34446099 PubMed Central PMC8393766.
  32. Kakko, K, Keskinen, P, Pihlakoski, L, Salmelin, R, Puura, K. In search of measures to improve the detection of increased cardiometabolic risk in children using second-generation antipsychotic medications. Nord J Psychiatry. 2022;76 (4):316-322. doi: 10.1080/08039488.2021.1968489. PubMed PMID:34431750 .
  33. Roslund, MI, Puhakka, R, Nurminen, N, Oikarinen, S, Siter, N, Grönroos, M et al.. Long-term biodiversity intervention shapes health-associated commensal microbiota among urban day-care children. Environ Int. 2021;157 :106811. doi: 10.1016/j.envint.2021.106811. PubMed PMID:34403882 .
  34. Oikarinen, S, Krogvold, L, Edwin, B, Buanes, T, Korsgren, O, Laiho, JE et al.. Characterisation of enterovirus RNA detected in the pancreas and other specimens of live patients with newly diagnosed type 1 diabetes in the DiViD study. Diabetologia. 2021;64 (11):2491-2501. doi: 10.1007/s00125-021-05525-0. PubMed PMID:34390364 PubMed Central PMC8494699.
  35. van Tilburg, CM, Pfaff, E, Pajtler, KW, Langenberg, KPS, Fiesel, P, Jones, BC et al.. The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets. Cancer Discov. 2021;11 (11):2764-2779. doi: 10.1158/2159-8290.CD-21-0094. PubMed PMID:34373263 PubMed Central PMC9414287.
  36. Kelloniemi, S, Heikkilä, P, Palmu, S. COVID-19 restrictions probably brought the 2019-2020 Finnish influenza season to an early end and led to fewer respiratory viruses among infants. Acta Paediatr. 2021;110 (12):3327-3328. doi: 10.1111/apa.16061. PubMed PMID:34363256 PubMed Central PMC8444869.
  37. Lachman, A, Burger, M, Jordaan, ER, Leppanen, J, Puura, K, Niehaus, DJH et al.. Maternal Shared Pleasure, Infant Withdrawal, and Developmental Outcomes in a High Risk Setting in South Africa. Front Psychiatry. 2021;12 :668009. doi: 10.3389/fpsyt.2021.668009. PubMed PMID:34354608 PubMed Central PMC8329093.
  38. Mohamad, MS, Mahadir Naidu, B, Kaltiala, R, Virtanen, SM, Lehtinen-Jacks, S. Thinness, overweight and obesity among 6- to 17-year-old Malaysians: secular trends and sociodemographic determinants from 2006 to 2015. Public Health Nutr. 2021;24 (18):6309-6322. doi: 10.1017/S1368980021003190. PubMed PMID:34348828 .
  39. Palomäki, A, FinnGen Rheumatology Clinical Expert Group, Palotie, A, Koskela, J, Eklund, KK, Pirinen, M et al.. Lifetime risk of rheumatoid arthritis-associated interstitial lung disease in MUC5B mutation carriers. Ann Rheum Dis. 2021;80 (12):1530-1536. doi: 10.1136/annrheumdis-2021-220698. PubMed PMID:34344703 PubMed Central PMC8600604.
  40. Mertens, AEJ, Kunst, AE, Lorant, V, Alves, J, Rimpelä, A, Clancy, L et al.. Smoking cessation among adolescents in Europe: The role of school policy and programmes. Drug Alcohol Depend. 2021;227 :108945. doi: 10.1016/j.drugalcdep.2021.108945. PubMed PMID:34333281 .
  41. Paavola, S, Lindfors, K, Kivelä, L, Cerqueira, J, Huhtala, H, Saavalainen, P et al.. Presence of high-risk HLA genotype is the most important individual risk factor for coeliac disease among at-risk relatives. Aliment Pharmacol Ther. 2021;54 (6):805-813. doi: 10.1111/apt.16534. PubMed PMID:34278595 .
  42. Magnusson, Å, Laivuori, H, Loft, A, Oldereid, NB, Pinborg, A, Petzold, M et al.. The Association Between High Birth Weight and Long-Term Outcomes-Implications for Assisted Reproductive Technologies: A Systematic Review and Meta-Analysis. Front Pediatr. 2021;9 :675775. doi: 10.3389/fped.2021.675775. PubMed PMID:34249812 PubMed Central PMC8260985.
  43. Immonen, E, Nikkilä, A, Peltomäki, T, Aine, L, Lohi, O. Late adverse effects of childhood acute lymphoblastic leukemia treatment on developing dentition. Pediatr Blood Cancer. 2021;68 (9):e29200. doi: 10.1002/pbc.29200. PubMed PMID:34228397 .
  44. Palmu, T, Lehtonen, J, Korhonen, L, Virtanen, SM, Niemelä, O, Toppari, J et al.. Association of different enteroviruses with atopy and allergic diseases in early childhood. Pediatr Allergy Immunol. 2021;32 (8):1629-1636. doi: 10.1111/pai.13577. PubMed PMID:34219290 .
  45. Holttinen, T, Pirkola, S, Rimpelä, M, Kaltiala, R. Factors behind a remarkable increase in adolescent psychiatric inpatient treatment between 1980 and 2010 – a nationwide register study. Nord J Psychiatry. 2022;76 (2):120-128. doi: 10.1080/08039488.2021.1939780. PubMed PMID:34185597 .
  46. Kivelä, J, Sormunen-Harju, H, Girchenko, PV, Huvinen, E, Stach-Lempinen, B, Kajantie, E et al.. Longitudinal Metabolic Profiling of Maternal Obesity, Gestational Diabetes, and Hypertensive Pregnancy Disorders. J Clin Endocrinol Metab. 2021;106 (11):e4372-e4388. doi: 10.1210/clinem/dgab475. PubMed PMID:34185058 PubMed Central PMC8530734.
  47. Mustaniemi, S, Nikkinen, H, Bloigu, A, Pouta, A, Kaaja, R, Eriksson, JG et al.. Normal Gestational Weight Gain Protects From Large-for-Gestational-Age Birth Among Women With Obesity and Gestational Diabetes. Front Public Health. 2021;9 :550860. doi: 10.3389/fpubh.2021.550860. PubMed PMID:34136447 PubMed Central PMC8200493.
  48. Keikkala, E, Forstén, J, Ritvos, O, Stenman, UH, Kajantie, E, Hämäläinen, E et al.. Serum Inhibin-A and PAPP-A2 in the prediction of pre-eclampsia during the first and second trimesters in high-risk women. Pregnancy Hypertens. 2021;25 :116-122. doi: 10.1016/j.preghy.2021.05.024. PubMed PMID:34116346 .
  49. Zekavat, SM, Lin, SH, Bick, AG, Liu, A, Paruchuri, K, Wang, C et al.. Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection. Nat Med. 2021;27 (6):1012-1024. doi: 10.1038/s41591-021-01371-0. PubMed PMID:34099924 PubMed Central PMC8245201.
  50. Jorgensen, JM, Young, R, Ashorn, P, Ashorn, U, Chaima, D, Davis, JCC et al.. Associations of Human Milk Oligosaccharides and Bioactive Proteins with Infant Morbidity and Inflammation in Malawian Mother-Infant Dyads. Curr Dev Nutr. 2021;5 (5):nzab072. doi: 10.1093/cdn/nzab072. PubMed PMID:34084993 PubMed Central PMC8163417.
  51. Liuska, PJ, Lemmelä, S, Havulinna, AS, Kaarniranta, K, Uusitalo, H, Laivuori, H et al.. Association of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population. JAMA Ophthalmol. 2021;139 (7):762-768. doi: 10.1001/jamaophthalmol.2021.1610. PubMed PMID:34081096 PubMed Central PMC8176385.
  52. Knaappila, N, Marttunen, M, Fröjd, S, Kaltiala, R. Changes over time in mental health symptoms among adolescents in Tampere, Finland. Scand J Child Adolesc Psychiatr Psychol. 2021;9 :96-104. doi: 10.21307/sjcapp-2021-011. PubMed PMID:34079771 PubMed Central PMC8132727.
  53. Mäkinen, A, Nikkilä, A, Mehtonen, J, Teppo, S, Oksa, L, Nordlund, J et al.. Expression of BCL6 in paediatric B-cell acute lymphoblastic leukaemia and association with prognosis. Pathology. 2021;53 (7):875-882. doi: 10.1016/j.pathol.2021.02.013. PubMed PMID:34049715 .
  54. Størdal, K, Kahrs, C, Tapia, G, Agardh, D, Kurppa, K, Stene, LC et al.. Letter: risk of coeliac disease-do microbial derived factors promote and protect? Authors’ reply. Aliment Pharmacol Ther. 2021;53 (12):1328. doi: 10.1111/apt.16389. PubMed PMID:34029413 .
  55. Csonka, P, Tapiainen, T, Mäkelä, MJ, Lehtimäki, L. Heterogeneity of emergency treatment practices in wheezing preschool children. Acta Paediatr. 2021;110 (8):2448-2454. doi: 10.1111/apa.15915. PubMed PMID:33987866 .
  56. Haahtela, T, Valovirta, E, Saarinen, K, Jantunen, J, Lindström, I, Kauppi, P et al.. The Finnish Allergy Program 2008-2018: Society-wide proactive program for change of management to mitigate allergy burden. J Allergy Clin Immunol. 2021;148 (2):319-326.e4. doi: 10.1016/j.jaci.2021.03.037. PubMed PMID:33965232 .
  57. Haahtela, T, Alenius, H, Lehtimäki, J, Sinkkonen, A, Fyhrquist, N, Hyöty, H et al.. Immunological resilience and biodiversity for prevention of allergic diseases and asthma. Allergy. 2021;76 (12):3613-3626. doi: 10.1111/all.14895. PubMed PMID:33959980 .
  58. Berntsen, S, Laivuori, H, la Cour Freiesleben, N, Loft, A, Söderström-Anttila, V, B Oldereid, N et al.. A systematic review and meta-analysis on the association between ICSI and chromosome abnormalities. Hum Reprod Update. 2021;27 (5):801-847. doi: 10.1093/humupd/dmab005. PubMed PMID:33956940 .
  59. Nurminen, N, Cerrone, D, Lehtonen, J, Parajuli, A, Roslund, M, Lönnrot, M et al.. Land Cover of Early-Life Environment Modulates the Risk of Type 1 Diabetes. Diabetes Care. 2021;44 (7):1506-1514. doi: 10.2337/dc20-1719. PubMed PMID:33952607 PubMed Central PMC8323192.
  60. Polkowska, A, Rinta-Kokko, H, Toropainen, M, Palmu, AA, Nuorti, JP. Long-term population effects of infant 10-valent pneumococcal conjugate vaccination on pneumococcal meningitis in Finland. Vaccine. 2021;39 (23):3216-3224. doi: 10.1016/j.vaccine.2021.02.030. PubMed PMID:33934915 .
  61. Dieckmann, L, Lahti-Pulkkinen, M, Kvist, T, Lahti, J, DeWitt, PE, Cruceanu, C et al.. Characteristics of epigenetic aging across gestational and perinatal tissues. Clin Epigenetics. 2021;13 (1):97. doi: 10.1186/s13148-021-01080-y. PubMed PMID:33926514 PubMed Central PMC8082803.
  62. Saarenpää, M, Roslund, MI, Puhakka, R, Grönroos, M, Parajuli, A, Hui, N et al.. Do Rural Second Homes Shape Commensal Microbiota of Urban Dwellers? A Pilot Study among Urban Elderly in Finland. Int J Environ Res Public Health. 2021;18 (7):. doi: 10.3390/ijerph18073742. PubMed PMID:33918486 PubMed Central PMC8038225.
  63. Deloria Knoll, M, Bennett, JC, Garcia Quesada, M, Kagucia, EW, Peterson, ME, Feikin, DR et al.. Global Landscape Review of Serotype-Specific Invasive Pneumococcal Disease Surveillance among Countries Using PCV10/13: The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) Project. Microorganisms. 2021;9 (4):. doi: 10.3390/microorganisms9040742. PubMed PMID:33918127 PubMed Central PMC8066045.
  64. Garcia Quesada, M, Yang, Y, Bennett, JC, Hayford, K, Zeger, SL, Feikin, DR et al.. Serotype Distribution of Remaining Pneumococcal Meningitis in the Mature PCV10/13 Period: Findings from the PSERENADE Project. Microorganisms. 2021;9 (4):. doi: 10.3390/microorganisms9040738. PubMed PMID:33916227 PubMed Central PMC8066874.
  65. Hannola, K, Hoppu, S, Mennander, S, Huhtala, H, Laivuori, H, Tihtonen, K et al.. Obstetric early warning system to predict maternal morbidity of pre-eclampsia, postpartum hemorrhage and infection after birth in high-risk women: a prospective cohort study. Midwifery. 2021;99 :103015. doi: 10.1016/j.midw.2021.103015. PubMed PMID:33915316 .
  66. Räisänen, PE, Haanperä, M, Soini, H, Ruutu, P, Nuorti, JP, Lyytikäinen, O et al.. Transmission of tuberculosis between foreign-born and Finnish-born populations in Finland, 2014-2017. PLoS One. 2021;16 (4):e0250674. doi: 10.1371/journal.pone.0250674. PubMed PMID:33891668 PubMed Central PMC8064540.
  67. Sinha, B, Sommerfelt, H, Ashorn, P, Mazumder, S, Taneja, S, More, D et al.. Effect of Community-Initiated Kangaroo Mother Care on Postpartum Depressive Symptoms and Stress Among Mothers of Low-Birth-Weight Infants: A Randomized Clinical Trial. JAMA Netw Open. 2021;4 (4):e216040. doi: 10.1001/jamanetworkopen.2021.6040. PubMed PMID:33885776 PubMed Central PMC8063066.
  68. Csonka, P, Tapiainen, T, Mäkelä, MJ, Lehtimäki, L. Optimal administration of bronchodilators with valved holding chambers in preschool children: a review of literature. Eur J Pediatr. 2021;180 (10):3101-3109. doi: 10.1007/s00431-021-04074-3. PubMed PMID:33877400 PubMed Central PMC8055476.
  69. Park, JJH, Ford, N, Xavier, D, Ashorn, P, Grais, RF, Bhutta, ZA et al.. Randomised trials at the level of the individual. Lancet Glob Health. 2021;9 (5):e691-e700. doi: 10.1016/S2214-109X(20)30540-4. PubMed PMID:33865474 .
  70. Park, JJH, Grais, RF, Taljaard, M, Nakimuli-Mpungu, E, Jehan, F, Nachega, JB et al.. Urgently seeking efficiency and sustainability of clinical trials in global health. Lancet Glob Health. 2021;9 (5):e681-e690. doi: 10.1016/S2214-109X(20)30539-8. PubMed PMID:33865473 PubMed Central PMC8424133.
  71. Natarajan, P, Pampana, A, Graham, SE, Ruotsalainen, SE, Perry, JA, de Vries, PS et al.. Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. Nat Commun. 2021;12 (1):2182. doi: 10.1038/s41467-021-22339-1. PubMed PMID:33846329 PubMed Central PMC8042019.
  72. Wright, CM, Macpherson, J, Bland, R, Ashorn, P, Zaman, S, Ho, FK et al.. Wasting and Stunting in Infants and Young Children as Risk Factors for Subsequent Stunting or Mortality: Longitudinal Analysis of Data from Malawi, South Africa, and Pakistan. J Nutr. 2021;151 (7):2022-2028. doi: 10.1093/jn/nxab054. PubMed PMID:33830247 PubMed Central PMC8245889.
  73. Karjalainen, L, Tikkanen, M, Rantanen, K, Aarnio, K, Korhonen, A, Saaros, A et al.. Stroke in Pregnancy and Puerperium: Validated Incidence Trends With Risk Factor Analysis in Finland 1987-2016. Neurology. 2021;96 (21):e2564-e2575. doi: 10.1212/WNL.0000000000011990. PubMed PMID:33827961 .
  74. Mäkinen, A, Nikkilä, A, Haapaniemi, T, Oksa, L, Mehtonen, J, Vänskä, M et al.IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia. Cancers (Basel). 2021;13 (7):. doi: 10.3390/cancers13071505. PubMed PMID:33805930 PubMed Central PMC8037952.
  75. Mohanraj, U, Jokinen, M, Thapa, RR, Paloniemi, M, Vesikari, T, Lappalainen, M et al.. Human Protoparvovirus DNA and IgG in Children and Adults with and without Respiratory or Gastrointestinal Infections. Viruses. 2021;13 (3):. doi: 10.3390/v13030483. PubMed PMID:33804173 PubMed Central PMC7999311.
  76. Bennett, JC, Hetrich, MK, Garcia Quesada, M, Sinkevitch, JN, Deloria Knoll, M, Feikin, DR et al.. Changes in Invasive Pneumococcal Disease Caused by Streptococcus pneumoniae Serotype 1 Following Introduction of PCV10 and PCV13: Findings from the PSERENADE Project. Microorganisms. 2021;9 (4):. doi: 10.3390/microorganisms9040696. PubMed PMID:33801760 PubMed Central PMC8066231.
  77. Kobeissi, L, Nair, M, Evers, ES, Han, MD, Aboubaker, S, Say, L et al.. Setting research priorities for sexual, reproductive, maternal, newborn, child and adolescent health in humanitarian settings. Confl Health. 2021;15 (1):16. doi: 10.1186/s13031-021-00353-w. PubMed PMID:33771212 PubMed Central PMC7995567.
  78. Yohannes, DA, Kaukinen, K, Kurppa, K, Saavalainen, P, Greco, D. Clustering based approach for population level identification of condition-associated T-cell receptor β-chain CDR3 sequences. BMC Bioinformatics. 2021;22 (1):159. doi: 10.1186/s12859-021-04087-7. PubMed PMID:33765908 PubMed Central PMC7993519.
  79. Abreu, AM, Young, RR, Buchanan, A, Lofgren, IE, Okronipa, HET, Lartey, A et al.. Maternal Blood Pressure in Relation to Prenatal Lipid-Based Nutrient Supplementation and Adverse Birth Outcomes in a Ghanaian Cohort: A Randomized Controlled Trial and Cohort Analysis. J Nutr. 2021;151 (6):1637-1645. doi: 10.1093/jn/nxab018. PubMed PMID:33704494 PubMed Central PMC8169808.
  80. Repo, M, Hannula, M, Taavela, J, Hyttinen, J, Isola, J, Hiltunen, P et al.. Iron Transporter Protein Expressions in Children with Celiac Disease. Nutrients. 2021;13 (3):. doi: 10.3390/nu13030776. PubMed PMID:33673530 PubMed Central PMC7997288.
  81. Kivistö, JE, Poutanen, R, Protudjer, JLP, Csonka, P, Korppi, M, Renko, M et al.. Current Care Guidelines had no immediate effects on antitussive prescriptions to Finnish children. Acta Paediatr. 2021;110 (8):2445-2447. doi: 10.1111/apa.15829. PubMed PMID:33662160 .
  82. Lafond, KE, Porter, RM, Whaley, MJ, Suizan, Z, Ran, Z, Aleem, MA et al.. Global burden of influenza-associated lower respiratory tract infections and hospitalizations among adults: A systematic review and meta-analysis. PLoS Med. 2021;18 (3):e1003550. doi: 10.1371/journal.pmed.1003550. PubMed PMID:33647033 PubMed Central PMC7959367.
  83. Ruohtula, T, Kondrashova, A, Lehtonen, J, Oikarinen, S, Hämäläinen, AM, Niemelä, O et al.. Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life. Front Immunol. 2020;11 :567046. doi: 10.3389/fimmu.2020.567046. PubMed PMID:33643278 PubMed Central PMC7905218.
  84. Bonifacio, E, Weiß, A, Winkler, C, Hippich, M, Rewers, MJ, Toppari, J et al.. An Age-Related Exponential Decline in the Risk of Multiple Islet Autoantibody Seroconversion During Childhood. Diabetes Care. 2021;44 (10):2260-8. doi: 10.2337/dc20-2122. PubMed PMID:33627366 PubMed Central PMC8929192.
  85. Oikarinen, M, Puustinen, L, Lehtonen, J, Hakola, L, Simell, S, Toppari, J et al.. Enterovirus Infections Are Associated With the Development of Celiac Disease in a Birth Cohort Study. Front Immunol. 2020;11 :604529. doi: 10.3389/fimmu.2020.604529. PubMed PMID:33603739 PubMed Central PMC7884453.
  86. Winter, G, Kirschner-Schwabe, R, Groeneveld-Krentz, S, Escherich, G, Möricke, A, von Stackelberg, A et al.. Clinical and genetic characteristics of children with acute lymphoblastic leukemia and Li-Fraumeni syndrome. Leukemia. 2021;35 (5):1475-1479. doi: 10.1038/s41375-021-01163-y. PubMed PMID:33580201 PubMed Central PMC8102191.
  87. Virtanen, A, Huttala, O, Tihtonen, K, Toimela, T, Heinonen, T, Laivuori, H et al.. Angiogenic Effect of Pravastatin Alone and with Sera from Healthy and Complicated Pregnancies Studied by in vitro Vasculogenesis/Angiogenesis Assay. J Vasc Res. 2021;58 (3):139-147. doi: 10.1159/000512831. PubMed PMID:33571991 .
  88. Haskell, MJ, Young, R, Adu-Afaruwah, S, Lartey, A, Okronipa, HET, Maleta, K et al.. Small-Quantity Lipid-Based Nutrient Supplements Do Not Affect Plasma or Milk Retinol Concentrations Among Malawian Mothers, or Plasma Retinol Concentrations among Young Malawian or Ghanaian Children in Two Randomized Trials. J Nutr. 2021;151 (4):1029-1037. doi: 10.1093/jn/nxaa439. PubMed PMID:33561214 PubMed Central PMC8030706.
  89. Hakola, L, Erlund, I, Cuthbertson, D, Miettinen, ME, Autio, R, Nucci, AM et al.. Serum fatty acids and risk of developing islet autoimmunity: A nested case-control study within the TRIGR birth cohort. Pediatr Diabetes. 2021;22 (4):577-585. doi: 10.1111/pedi.13189. PubMed PMID:33543815 .
  90. Lokki, AI, Teirilä, L, Triebwasser, M, Daly, E, Bhattacharjee, A, Uotila, L et al.. Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study. BJOG. 2021;128 (8):1282-1291. doi: 10.1111/1471-0528.16660. PubMed PMID:33539617 PubMed Central PMC8255276.
  91. Jääskeläinen, T, Kärkkäinen, O, Jokkala, J, Klåvus, A, Heinonen, S, Auriola, S et al.. A non-targeted LC-MS metabolic profiling of pregnancy: longitudinal evidence from healthy and pre-eclamptic pregnancies. Metabolomics. 2021;17 (2):20. doi: 10.1007/s11306-020-01752-5. PubMed PMID:33515103 PubMed Central PMC7846510.
  92. Gaffey, MF, Waldman, RJ, Blanchet, K, Amsalu, R, Capobianco, E, Ho, LS et al.. Delivering health and nutrition interventions for women and children in different conflict contexts: a framework for decision making on what, when, and how. Lancet. 2021;397 (10273):543-554. doi: 10.1016/S0140-6736(21)00133-1. PubMed PMID:33503457 .
  93. Heino, E, Ellonen, N, Kaltiala, R. Transgender Identity Is Associated With Bullying Involvement Among Finnish Adolescents. Front Psychol. 2020;11 :612424. doi: 10.3389/fpsyg.2020.612424. PubMed PMID:33488479 PubMed Central PMC7820417.
  94. Cerqueira, JXM, Saavalainen, P, Kurppa, K, Laurikka, P, Huhtala, H, Nykter, M et al.. Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes. J Hum Genet. 2021;66 (6):613-623. doi: 10.1038/s10038-020-00888-5. PubMed PMID:33446885 PubMed Central PMC8144013.
  95. Strausz, S, Kiiskinen, T, Broberg, M, Ruotsalainen, S, Koskela, J, Bachour, A et al.. Sleep apnoea is a risk factor for severe COVID-19. BMJ Open Respir Res. 2021;8 (1):. doi: 10.1136/bmjresp-2020-000845. PubMed PMID:33436406 PubMed Central PMC7804843.
  96. Mlinarić, M, Kohler, E, Kunst, AE, Lorant, V, Rimpelä, A, Hoffmann, L et al.. The association between migration and smoke-free families: how do migrants from different world regions compare?. Eur J Public Health. 2021;31 (2):333-340. doi: 10.1093/eurpub/ckaa241. PubMed PMID:33403397 .
  97. Maleta, K, Fan, YM, Luoma, J, Ashorn, U, Bendabenda, J, Dewey, KG et al.. Infections and systemic inflammation are associated with lower plasma concentration of insulin-like growth factor I among Malawian children. Am J Clin Nutr. 2021;113 (2):380-390. doi: 10.1093/ajcn/nqaa327. PubMed PMID:33381802 PubMed Central PMC7851819.
  98. Kurppa, K, Kivelä, L, Kaukinen, K. Letter: no-biopsy pathway for diagnosing adult coeliac disease-authors’ reply. Aliment Pharmacol Ther. 2021;53 (2):359. doi: 10.1111/apt.16195. PubMed PMID:33368505 .
  99. Halton, J, Brandão, LR, Luciani, M, Bomgaars, L, Chalmers, E, Mitchell, LG et al.. Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial. Lancet Haematol. 2021;8 (1):e22-e33. doi: 10.1016/S2352-3026(20)30368-9. PubMed PMID:33290737 .
  100. Vari, HK, Roslund, MI, Oikarinen, S, Nurminen, N, Puhakka, R, Parajuli, A et al.. Associations between land cover categories, gaseous PAH levels in ambient air and endocrine signaling predicted from gut bacterial metagenome of the elderly. Chemosphere. 2021;265 :128965. doi: 10.1016/j.chemosphere.2020.128965. PubMed PMID:33248729 .
  101. Poutanen, R, Virta, T, Heikkilä, P, Pauniaho, SL, Csonka, P, Korppi, M et al.. National Current Care Guidelines for paediatric lower respiratory tract infections reduced the use of chest radiographs but local variations were observed. Acta Paediatr. 2021;110 (5):1594-1600. doi: 10.1111/apa.15692. PubMed PMID:33247995 .
  102. Jaatinen, N, Jääskeläinen, T, FINNPEC, Laivuori, H, Ekholm, E. The non-traditional and familial risk factors for preeclampsia in the FINNPEC cohort. Pregnancy Hypertens. 2021;23 :48-55. doi: 10.1016/j.preghy.2020.11.001. PubMed PMID:33221706 .
  103. Størdal, K, Kahrs, C, Tapia, G, Agardh, D, Kurppa, K, Stene, LC et al.. Review article: exposure to microbes and risk of coeliac disease. Aliment Pharmacol Ther. 2021;53 (1):43-62. doi: 10.1111/apt.16161. PubMed PMID:33210316 .
  104. Ashorn, P. Infant Growth After Maternal Dietary Supplementation Before and During Pregnancy. J Pediatr. 2021;229 :14-16. doi: 10.1016/j.jpeds.2020.10.076. PubMed PMID:33159913 .
  105. Liu, Z, Fan, YM, Ashorn, P, Cheung, YB, Hallamaa, L, Hyöty, H et al.. Faecal regenerating 1B protein concentration is not associated with child growth in rural Malawi. J Paediatr Child Health. 2021;57 (3):388-394. doi: 10.1111/jpc.15231. PubMed PMID:33112481 PubMed Central PMC8048694.
  106. Ruotsalainen, SE, Partanen, JJ, Cichonska, A, Lin, J, Benner, C, Surakka, I et al.. An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease. Eur J Hum Genet. 2021;29 (2):309-324. doi: 10.1038/s41431-020-00730-8. PubMed PMID:33110245 PubMed Central PMC7868371.
  107. Jorgensen, JM, Young, R, Ashorn, P, Ashorn, U, Chaima, D, Davis, JCC et al.. Associations of human milk oligosaccharides and bioactive proteins with infant growth and development among Malawian mother-infant dyads. Am J Clin Nutr. 2021;113 (1):209-220. doi: 10.1093/ajcn/nqaa272. PubMed PMID:33096556 PubMed Central PMC7779225.
  108. Kinnunen, JM, Rimpelä, AH, Lindfors, PL, Clancy, L, Alves, J, Hoffmann, L et al.. Electronic cigarette use among 14- to 17-year-olds in Europe. Eur J Public Health. 2021;31 (2):402-408. doi: 10.1093/eurpub/ckaa145. PubMed PMID:33079986 PubMed Central PMC8071596.
  109. Adu-Afarwuah, S, Arnold, CD, Maleta, K, Ashorn, P, Ashorn, U, Jorgensen, JM et al.. Consumption of multiple micronutrients or small-quantity lipid-based nutrient supplements containing iodine at the recommended dose during pregnancy, compared with iron and folic acid, does not affect women’s urinary iodine concentration in rural Malawi: a secondary outcome analysis of the iLiNS DYAD trial. Public Health Nutr. 2021;24 (10):3049-3057. doi: 10.1017/S1368980020003250. PubMed PMID:33054890 PubMed Central PMC9884741.
  110. Tuovinen, S, Lahti-Pulkkinen, M, Girchenko, P, Heinonen, K, Lahti, J, Reynolds, RM et al.. Maternal antenatal stress and mental and behavioral disorders in their children. J Affect Disord. 2021;278 :57-65. doi: 10.1016/j.jad.2020.09.063. PubMed PMID:32950844 .
  111. Airaksinen, L, Myllymäki, L, Kaukinen, K, Saavalainen, P, Huhtala, H, Lindfors, K et al.. Differences Between Familial and Sporadic Celiac Disease. Dig Dis Sci. 2021;66 (6):1981-1988. doi: 10.1007/s10620-020-06490-1. PubMed PMID:32705440 PubMed Central PMC8163668.
  112. Jarvis, KB, Andersson, NG, Giertz, M, Järvelä, L, Lindinger, O, Långström, S et al.. Asymptomatic Right Atrial Thrombosis After Acute Lymphoblastic Leukemia Treatment. J Pediatr Hematol Oncol. 2021;43 (4):e564-e566. doi: 10.1097/MPH.0000000000001848. PubMed PMID:32555028 .
  113. Popp, A, Arvola, T, Taavela, J, Kivelä, L, Ene, A, Laurila, K et al.. Nonbiopsy Approach for Celiac Disease Is Accurate When Using Exact Duodenal Histomorphometry: Prospective Study in 2 Countries. J Clin Gastroenterol. 2021;55 (3):227-232. doi: 10.1097/MCG.0000000000001349. PubMed PMID:32301831 .

Search PubMed

2020

  1. Ruohtula, T, Kondrashova, A, Lehtonen, J, Oikarinen, S, Hämäläinen, AM, Niemelä, O et al.. Immunomodulatory Effects of Rhinovirus and Enterovirus Infections During the First Year of Life. Front Immunol. 2020;11 :567046. doi: 10.3389/fimmu.2020.567046. PubMed PMID:33643278 PubMed Central PMC7905218.
  2. Oikarinen, M, Puustinen, L, Lehtonen, J, Hakola, L, Simell, S, Toppari, J et al.. Enterovirus Infections Are Associated With the Development of Celiac Disease in a Birth Cohort Study. Front Immunol. 2020;11 :604529. doi: 10.3389/fimmu.2020.604529. PubMed PMID:33603739 PubMed Central PMC7884453.
  3. Heino, E, Fröjd, S, Marttunen, M, Kaltiala, R. Normative and negative sexual experiences of transgender identifying adolescents in the community. Scand J Child Adolesc Psychiatr Psychol. 2020;8 :166-175. doi: 10.21307/sjcapp-2020-017. PubMed PMID:33564633 PubMed Central PMC7866780.
  4. Knaappila, N, Marttunen, M, Fröjd, S, Lindberg, N, Kaltiala, R. Changes in cannabis use according to socioeconomic status among Finnish adolescents from 2000 to 2015. J Cannabis Res. 2020;2 (1):44. doi: 10.1186/s42238-020-00052-y. PubMed PMID:33526131 PubMed Central PMC7819333.
  5. Heino, E, Ellonen, N, Kaltiala, R. Transgender Identity Is Associated With Bullying Involvement Among Finnish Adolescents. Front Psychol. 2020;11 :612424. doi: 10.3389/fpsyg.2020.612424. PubMed PMID:33488479 PubMed Central PMC7820417.
  6. Yohannes, DA, de Kauwe, A, Kaukinen, K, Kurppa, K, Mäki, M, Anderson, RP et al.. Effects of In Vivo Gluten Challenge on PBMC Gene Expression Profiles in Diet Treated Celiac Disease. Front Immunol. 2020;11 :594243. doi: 10.3389/fimmu.2020.594243. PubMed PMID:33362776 PubMed Central PMC7759501.
  7. Olsen, MF, Iuel-Brockdorff, AS, Yaméogo, CW, Cichon, B, Fabiansen, C, Filteau, S et al.. Impact of food supplements on early child development in children with moderate acute malnutrition: A randomised 2 x 2 x 3 factorial trial in Burkina Faso. PLoS Med. 2020;17 (12):e1003442. doi: 10.1371/journal.pmed.1003442. PubMed PMID:33362221 PubMed Central PMC7757806.
  8. Suarez, A, Lahti, J, Lahti-Pulkkinen, M, Girchenko, P, Czamara, D, Arloth, J et al.. A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders. Neurobiol Stress. 2020;13 :100275. doi: 10.1016/j.ynstr.2020.100275. PubMed PMID:33344728 PubMed Central PMC7739178.
  9. Allotey, J, Snell, KI, Smuk, M, Hooper, R, Chan, CL, Ahmed, A et al.. Validation and development of models using clinical, biochemical and ultrasound markers for predicting pre-eclampsia: an individual participant data meta-analysis. Health Technol Assess. 2020;24 (72):1-252. doi: 10.3310/hta24720. PubMed PMID:33336645 PubMed Central PMC7780127.
  10. Abuhamed, J, Nikkilä, A, Lohi, O, Auvinen, A. Trends of computed tomography use among children in Finland. Eur J Radiol Open. 2020;7 :100290. doi: 10.1016/j.ejro.2020.100290. PubMed PMID:33335951 PubMed Central PMC7733003.
  11. Mars, N, Widén, E, Kerminen, S, Meretoja, T, Pirinen, M, Della Briotta Parolo, P et al.. The role of polygenic risk and susceptibility genes in breast cancer over the course of life. Nat Commun. 2020;11 (1):6383. doi: 10.1038/s41467-020-19966-5. PubMed PMID:33318493 PubMed Central PMC7736877.
  12. Airaksinen, L, Laurikka, P, Huhtala, H, Kurppa, K, Salmi, T, Saavalainen, P et al.. Influence of HLA-DQ2.5 Dose on Clinical Picture of Unrelated Celiac Disease Patients. Nutrients. 2020;12 (12):. doi: 10.3390/nu12123775. PubMed PMID:33317091 PubMed Central PMC7764246.
  13. Doku, DT, Neupane, S, Dobewall, H, Rimpelä, A. Alcohol-related mortality and all-cause mortality following bereavement in two successive generations. PLoS One. 2020;15 (12):e0243290. doi: 10.1371/journal.pone.0243290. PubMed PMID:33301516 PubMed Central PMC7728282.
  14. Salmikangas, S, Laiho, JE, Kalander, K, Laajala, M, Honkimaa, A, Shanina, I et al.. Detection of Viral -RNA and +RNA Strands in Enterovirus-Infected Cells and Tissues. Microorganisms. 2020;8 (12):. doi: 10.3390/microorganisms8121928. PubMed PMID:33291747 PubMed Central PMC7761939.
  15. Halton, J, Brandão, LR, Luciani, M, Bomgaars, L, Chalmers, E, Mitchell, LG et al.. Dabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial. Lancet Haematol. 2021;8 (1):e22-e33. doi: 10.1016/S2352-3026(20)30368-9. PubMed PMID:33290737 .
  16. Vari, HK, Roslund, MI, Oikarinen, S, Nurminen, N, Puhakka, R, Parajuli, A et al.. Associations between land cover categories, gaseous PAH levels in ambient air and endocrine signaling predicted from gut bacterial metagenome of the elderly. Chemosphere. 2021;265 :128965. doi: 10.1016/j.chemosphere.2020.128965. PubMed PMID:33248729 .
  17. Poutanen, R, Virta, T, Heikkilä, P, Pauniaho, SL, Csonka, P, Korppi, M et al.. National Current Care Guidelines for paediatric lower respiratory tract infections reduced the use of chest radiographs but local variations were observed. Acta Paediatr. 2021;110 (5):1594-1600. doi: 10.1111/apa.15692. PubMed PMID:33247995 .
  18. Steinthorsdottir, V, McGinnis, R, Williams, NO, Stefansdottir, L, Thorleifsson, G, Shooter, S et al.. Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women. Nat Commun. 2020;11 (1):5976. doi: 10.1038/s41467-020-19733-6. PubMed PMID:33239696 PubMed Central PMC7688949.
  19. Aboubaker, S, Evers, ES, Kobeissi, L, Francis, L, Najjemba, R, Miller, NP et al.. The availability of global guidance for the promotion of women’s, newborns’, children’s and adolescents’ health and nutrition in conflicts. BMJ Glob Health. 2020;5 (Suppl 1):. doi: 10.1136/bmjgh-2019-002060. PubMed PMID:33223502 PubMed Central PMC7684670.
  20. Jaatinen, N, Jääskeläinen, T, FINNPEC, Laivuori, H, Ekholm, E. The non-traditional and familial risk factors for preeclampsia in the FINNPEC cohort. Pregnancy Hypertens. 2021;23 :48-55. doi: 10.1016/j.preghy.2020.11.001. PubMed PMID:33221706 .
  21. Mehtonen, J, Teppo, S, Lahnalampi, M, Kokko, A, Kaukonen, R, Oksa, L et al.. Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities. Genome Med. 2020;12 (1):99. doi: 10.1186/s13073-020-00799-2. PubMed PMID:33218352 PubMed Central PMC7679990.
  22. Størdal, K, Kahrs, C, Tapia, G, Agardh, D, Kurppa, K, Stene, LC et al.. Review article: exposure to microbes and risk of coeliac disease. Aliment Pharmacol Ther. 2021;53 (1):43-62. doi: 10.1111/apt.16161. PubMed PMID:33210316 .
  23. Honkimaa, A, Kimura, B, Sioofy-Khojine, AB, Lin, J, Laiho, J, Oikarinen, S et al.. Genetic Adaptation of Coxsackievirus B1 during Persistent Infection in Pancreatic Cells. Microorganisms. 2020;8 (11):. doi: 10.3390/microorganisms8111790. PubMed PMID:33203081 PubMed Central PMC7697981.
  24. Neumann, A, Walton, E, Alemany, S, Cecil, C, González, JR, Jima, DD et al.. Association between DNA methylation and ADHD symptoms from birth to school age: a prospective meta-analysis. Transl Psychiatry. 2020;10 (1):398. doi: 10.1038/s41398-020-01058-z. PubMed PMID:33184255 PubMed Central PMC7665047.
  25. Manninen, T, Saudargiene, A, Linne, ML. Astrocyte-mediated spike-timing-dependent long-term depression modulates synaptic properties in the developing cortex. PLoS Comput Biol. 2020;16 (11):e1008360. doi: 10.1371/journal.pcbi.1008360. PubMed PMID:33170856 PubMed Central PMC7654831.
  26. Ashorn, P. Infant Growth After Maternal Dietary Supplementation Before and During Pregnancy. J Pediatr. 2021;229 :14-16. doi: 10.1016/j.jpeds.2020.10.076. PubMed PMID:33159913 .
  27. Snell, KIE, Allotey, J, Smuk, M, Hooper, R, Chan, C, Ahmed, A et al.. External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis. BMC Med. 2020;18 (1):302. doi: 10.1186/s12916-020-01766-9. PubMed PMID:33131506 PubMed Central PMC7604970.
  28. Rubio-San-Simón, A, André, N, Cefalo, MG, Aerts, I, Castañeda, A, Benezech, S et al.. Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe: A report from the Innovative Therapies for Children with Cancer (ITCC) consortium. Eur J Cancer. 2020;141 :82-91. doi: 10.1016/j.ejca.2020.09.024. PubMed PMID:33129040 PubMed Central PMC7546235.
  29. Liu, Z, Fan, YM, Ashorn, P, Cheung, YB, Hallamaa, L, Hyöty, H et al.. Faecal regenerating 1B protein concentration is not associated with child growth in rural Malawi. J Paediatr Child Health. 2021;57 (3):388-394. doi: 10.1111/jpc.15231. PubMed PMID:33112481 PubMed Central PMC8048694.
  30. Ruotsalainen, SE, Partanen, JJ, Cichonska, A, Lin, J, Benner, C, Surakka, I et al.. An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease. Eur J Hum Genet. 2021;29 (2):309-324. doi: 10.1038/s41431-020-00730-8. PubMed PMID:33110245 PubMed Central PMC7868371.
  31. Bao, EL, Nandakumar, SK, Liao, X, Bick, AG, Karjalainen, J, Tabaka, M et al.. Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells. Nature. 2020;586 (7831):769-775. doi: 10.1038/s41586-020-2786-7. PubMed PMID:33057200 PubMed Central PMC7606745.
  32. Roslund, MI, Puhakka, R, Grönroos, M, Nurminen, N, Oikarinen, S, Gazali, AM et al.. Biodiversity intervention enhances immune regulation and health-associated commensal microbiota among daycare children. Sci Adv. 2020;6 (42):. doi: 10.1126/sciadv.aba2578. PubMed PMID:33055153 PubMed Central PMC7556828.
  33. Adu-Afarwuah, S, Arnold, CD, Maleta, K, Ashorn, P, Ashorn, U, Jorgensen, JM et al.. Consumption of multiple micronutrients or small-quantity lipid-based nutrient supplements containing iodine at the recommended dose during pregnancy, compared with iron and folic acid, does not affect women’s urinary iodine concentration in rural Malawi: a secondary outcome analysis of the iLiNS DYAD trial. Public Health Nutr. 2021;24 (10):3049-3057. doi: 10.1017/S1368980020003250. PubMed PMID:33054890 PubMed Central PMC9884741.
  34. Äärelä, L, Hiltunen, P, Soini, T, Vuorela, N, Huhtala, H, Nevalainen, PI et al.. Type 1 tyrosinemia in Finland: a nationwide study. Orphanet J Rare Dis. 2020;15 (1):281. doi: 10.1186/s13023-020-01547-w. PubMed PMID:33046095 PubMed Central PMC7549233.
  35. Fabiansen, C, Cichon, B, Yaméogo, CW, Iuel-Brockdorf, AS, Phelan, KPQ, Wells, JC et al.. Publisher Correction: Association between admission criteria and body composition among young children with moderate acute malnutrition, a cross-sectional study from Burkina Faso. Sci Rep. 2020;10 (1):16914. doi: 10.1038/s41598-020-73323-6. PubMed PMID:33020533 PubMed Central PMC7536289.
  36. Pyykkö, J, Ashorn, U, Chilora, E, Maleta, K, Ashorn, P, Leppänen, JM et al.. Associations between individual variations in visual attention at 9 months and behavioral competencies at 18 months in rural Malawi. PLoS One. 2020;15 (10):e0239613. doi: 10.1371/journal.pone.0239613. PubMed PMID:33002053 PubMed Central PMC7529224.
  37. Dhingra, U, Kisenge, R, Sudfeld, CR, Dhingra, P, Somji, S, Dutta, A et al.. Lower-Dose Zinc for Childhood Diarrhea – A Randomized, Multicenter Trial. N Engl J Med. 2020;383 (13):1231-1241. doi: 10.1056/NEJMoa1915905. PubMed PMID:32966722 PubMed Central PMC7466932.
  38. Saarinen, NVV, Lehtonen, J, Veijola, R, Lempainen, J, Knip, M, Hyöty, H et al.. Correction: Saarinen, N.V.V., et al. Multiplexed High-Throughput Serological Assay for Human Enteroviruses. Microorganismis 2020, 8, 963. Microorganisms. 2020;8 (9):. doi: 10.3390/microorganisms8091426. PubMed PMID:32957450 PubMed Central PMC7563745.
  39. Tuovinen, S, Lahti-Pulkkinen, M, Girchenko, P, Heinonen, K, Lahti, J, Reynolds, RM et al.. Maternal antenatal stress and mental and behavioral disorders in their children. J Affect Disord. 2021;278 :57-65. doi: 10.1016/j.jad.2020.09.063. PubMed PMID:32950844 .
  40. Dufva, O, Pölönen, P, Brück, O, Keränen, MAI, Klievink, J, Mehtonen, J et al.. Immunogenomic Landscape of Hematological Malignancies. Cancer Cell. 2020;38 (3):424-428. doi: 10.1016/j.ccell.2020.08.019. PubMed PMID:32931743 .
  41. Ashorn, P, Black, RE, Lawn, JE, Ashorn, U, Klein, N, Hofmeyr, J et al.. The Lancet Small Vulnerable Newborn Series: science for a healthy start. Lancet. 2020;396 (10253):743-745. doi: 10.1016/S0140-6736(20)31906-1. PubMed PMID:32919498 .
  42. Ylönen, V, Lindfors, K, Repo, M, Huhtala, H, Fuchs, V, Saavalainen, P et al.. Non-Biopsy Serology-Based Diagnosis of Celiac Disease in Adults Is Accurate with Different Commercial Kits and Pre-Test Probabilities. Nutrients. 2020;12 (9):. doi: 10.3390/nu12092736. PubMed PMID:32911716 PubMed Central PMC7551634.
  43. Hughes, RL, Arnold, CD, Young, RR, Ashorn, P, Maleta, K, Fan, YM et al.. Infant gut microbiota characteristics generally do not modify effects of lipid-based nutrient supplementation on growth or inflammation: secondary analysis of a randomized controlled trial in Malawi. Sci Rep. 2020;10 (1):14861. doi: 10.1038/s41598-020-71922-x. PubMed PMID:32908192 PubMed Central PMC7481312.
  44. Koskimaa, S, Kivelä, L, Arvola, T, Hiltunen, P, Huhtala, H, Kaukinen, K et al.. Clinical characteristics and long-term health in celiac disease patients diagnosed in early childhood: Large cohort study. Dig Liver Dis. 2020;52 (11):1315-1322. doi: 10.1016/j.dld.2020.08.010. PubMed PMID:32900652 .
  45. Hankaniemi, MM, Baikoghli, MA, Stone, VM, Xing, L, Väätäinen, O, Soppela, S et al.. Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine. Microorganisms. 2020;8 (9):. doi: 10.3390/microorganisms8091287. PubMed PMID:32846899 PubMed Central PMC7565060.
  46. Sinisalu, L, Sen, P, Salihović, S, Virtanen, SM, Hyöty, H, Ilonen, J et al.. Early-life exposure to perfluorinated alkyl substances modulates lipid metabolism in progression to celiac disease. Environ Res. 2020;188 :109864. doi: 10.1016/j.envres.2020.109864. PubMed PMID:32846648 .
  47. Laukkanen, S, Oksa, L, Nikkilä, A, Lahnalampi, M, Parikka, M, Seki, M et al.. SIX6 is a TAL1-regulated transcription factor in T-ALL and associated with inferior outcome. Leuk Lymphoma. 2020;61 (13):3089-3100. doi: 10.1080/10428194.2020.1804560. PubMed PMID:32835548 .
  48. Ferrat, LA, Vehik, K, Sharp, SA, Lernmark, Å, Rewers, MJ, She, JX et al.. A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat Med. 2020;26 (8):1247-1255. doi: 10.1038/s41591-020-0930-4. PubMed PMID:32770166 PubMed Central PMC7556983.
  49. Fabiansen, C, Cichon, B, Yaméogo, CW, Iuel-Brockdorf, AS, Phelan, KPQ, Wells, JC et al.. Association between admission criteria and body composition among young children with moderate acute malnutrition, a cross-sectional study from Burkina Faso. Sci Rep. 2020;10 (1):13266. doi: 10.1038/s41598-020-69987-9. PubMed PMID:32764545 PubMed Central PMC7413376.
  50. Virta, J, Hannula, M, Tamminen, I, Lindfors, K, Kaukinen, K, Popp, A et al.. X-ray microtomography is a novel method for accurate evaluation of small-bowel mucosal morphology and surface area. Sci Rep. 2020;10 (1):13164. doi: 10.1038/s41598-020-69487-w. PubMed PMID:32753621 PubMed Central PMC7403326.
  51. Immonen, E, Aine, L, Nikkilä, A, Parikka, M, Grönroos, M, Vepsäläinen, K et al.. Randomized controlled and double-blinded study of Caphosol versus saline oral rinses in pediatric patients with cancer. Pediatr Blood Cancer. 2020;67 (10):e28520. doi: 10.1002/pbc.28520. PubMed PMID:32725875 .
  52. Airaksinen, L, Myllymäki, L, Kaukinen, K, Saavalainen, P, Huhtala, H, Lindfors, K et al.. Differences Between Familial and Sporadic Celiac Disease. Dig Dis Sci. 2021;66 (6):1981-1988. doi: 10.1007/s10620-020-06490-1. PubMed PMID:32705440 PubMed Central PMC8163668.
  53. Chan, LN, Murakami, MA, Robinson, ME, Caeser, R, Sadras, T, Lee, J et al.. Signalling input from divergent pathways subverts B cell transformation. Nature. 2020;583 (7818):845-851. doi: 10.1038/s41586-020-2513-4. PubMed PMID:32699415 PubMed Central PMC7394729.
  54. Virtanen, A, Huttala, O, Tihtonen, K, Toimela, T, Heinonen, T, Laivuori, H et al.. Therapeutic doses of metformin do not have impact on angiogenesis in presence of sera from pre-eclamptic, IUGR and healthy pregnancies. Pregnancy Hypertens. 2020;22 :7-13. doi: 10.1016/j.preghy.2020.06.008. PubMed PMID:32682321 .
  55. Wedenoja, S, Yoshihara, M, Teder, H, Sariola, H, Gissler, M, Katayama, S et al.. Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia. EBioMedicine. 2020;59 :102872. doi: 10.1016/j.ebiom.2020.102872. PubMed PMID:32680723 PubMed Central PMC7502669.
  56. Oikarinen, M, Bertolet, L, Toniolo, A, Oikarinen, S, Laiho, JE, Pugliese, A et al.. Differential Detection of Encapsidated versus Unencapsidated Enterovirus RNA in Samples Containing Pancreatic Enzymes-Relevance for Diabetes Studies. Viruses. 2020;12 (7):. doi: 10.3390/v12070747. PubMed PMID:32664501 PubMed Central PMC7411921.
  57. Robert, PO, Grard, A, Mélard, N, Mlinarić, M, Rimpelä, A, Richter, M et al.. The effect of school smoke-free policies on smoking stigmatization: A European comparison study among adolescents. PLoS One. 2020;15 (7):e0235772. doi: 10.1371/journal.pone.0235772. PubMed PMID:32663217 PubMed Central PMC7360046.
  58. Dufva, O, Pölönen, P, Brück, O, Keränen, MAI, Klievink, J, Mehtonen, J et al.. Immunogenomic Landscape of Hematological Malignancies. Cancer Cell. 2020;38 (3):380-399.e13. doi: 10.1016/j.ccell.2020.06.002. PubMed PMID:32649887 .
  59. Vehik, K, Bonifacio, E, Lernmark, Å, Yu, L, Williams, A, Schatz, D et al.. Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study. Diabetes Care. 2020;43 (9):2066-2073. doi: 10.2337/dc19-2547. PubMed PMID:32641373 PubMed Central PMC7440899.
  60. Rantalainen, V, Binder, EB, Lahti-Pulkkinen, M, Czamara, D, Laivuori, H, Villa, PM et al.. Polygenic prediction of the risk of perinatal depressive symptoms. Depress Anxiety. 2020;37 (9):862-875. doi: 10.1002/da.23066. PubMed PMID:32627298 .
  61. Saarinen, NVV, Lehtonen, J, Veijola, R, Lempainen, J, Knip, M, Hyöty, H et al.. Multiplexed High-Throughput Serological Assay for Human Enteroviruses. Microorganisms. 2020;8 (6):. doi: 10.3390/microorganisms8060963. PubMed PMID:32604930 PubMed Central PMC7355947.
  62. Njuma Libwea, J, Gröndahl-Yli-Hannuksela, K, Kobela, M, Toropainen, M, Nyholm, O, Ndombo, PK et al.. Prevalence of pneumococcal nasopharyngeal colonization and serotypes circulating in Cameroonian children after the 13-valent pneumococcal conjugate vaccine introduction. Int J Infect Dis. 2020;98 :113-120. doi: 10.1016/j.ijid.2020.06.048. PubMed PMID:32562849 .
  63. Smith, EL, Wheeler, I, Adler, H, Ferreira, DM, Sá-Leão, R, Abdullahi, O et al.. Upper airways colonisation of Streptococcus pneumoniae in adults aged 60 years and older: A systematic review of prevalence and individual participant data meta-analysis of risk factors. J Infect. 2020;81 (4):540-548. doi: 10.1016/j.jinf.2020.06.028. PubMed PMID:32562794 PubMed Central PMC7532703.
  64. Räisänen, PE, Soini, H, Tiittala, P, Snellman, O, Ruutu, P, Nuorti, JP et al.. Tuberculosis screening of asylum seekers in Finland, 2015-2016. BMC Public Health. 2020;20 (1):969. doi: 10.1186/s12889-020-09122-5. PubMed PMID:32560720 PubMed Central PMC7305613.
  65. Bramham, K, Villa, PM, Joslin, JR, Laivuori, H, Hämäläinen, E, Kajantie, E et al.. Predisposition to superimposed preeclampsia in women with chronic hypertension: endothelial, renal, cardiac, and placental factors in a prospective longitudinal cohort. Hypertens Pregnancy. 2020;39 (3):326-335. doi: 10.1080/10641955.2020.1769643. PubMed PMID:32479208 .
  66. Honkimaa, A, Sioofy-Khojine, AB, Oikarinen, S, Bertin, A, Hober, D, Hyöty, H et al.. Eradication of persistent coxsackievirus B infection from a pancreatic cell line with clinically used antiviral drugs. J Clin Virol. 2020;128 :104334. doi: 10.1016/j.jcv.2020.104334. PubMed PMID:32450550 .
  67. Mélard, N, Grard, A, Robert, PO, Kuipers, MAG, Schreuders, M, Rimpelä, AH et al.. School tobacco policies and adolescent smoking in six European cities in 2013 and 2016: A school-level longitudinal study. Prev Med. 2020;138 :106142. doi: 10.1016/j.ypmed.2020.106142. PubMed PMID:32450162 .
  68. Smolander, M, Nurminen, S, Repo, M, Kivelä, L, Kivistö, JE, Hiltunen, P et al.. Prevalence and clinical significance of esophageal abnormalities in children with celiac disease. Dis Esophagus. 2020;33 (11):. doi: 10.1093/dote/doaa033. PubMed PMID:32444881 .
  69. Palmu, AA, Rinta-Kokko, H, Nohynek, H, Nuorti, JP. Indirect Impact of Ten-valent Pneumococcal Conjugate Vaccine Program on Reducing Antimicrobial Use and Tympanostomy Tube Placements in Finland. Pediatr Infect Dis J. 2020;39 (9):862-866. doi: 10.1097/INF.0000000000002696. PubMed PMID:32412982 .
  70. Keikkala, E, Mustaniemi, S, Koivunen, S, Kinnunen, J, Viljakainen, M, Männisto, T et al.. Cohort Profile: The Finnish Gestational Diabetes (FinnGeDi) Study. Int J Epidemiol. 2020;49 (3):762-763g. doi: 10.1093/ije/dyaa039. PubMed PMID:32374401 PubMed Central PMC7394962.
  71. Rimpelä, A, Kinnunen, JM, Lindfors, P, Soto, VE, Salmela-Aro, K, Perelman, J et al.. Academic Well-Being and Structural Characteristics of Peer Networks in School. Int J Environ Res Public Health. 2020;17 (8):. doi: 10.3390/ijerph17082848. PubMed PMID:32326162 PubMed Central PMC7216150.
  72. Lahti-Pulkkinen, M, Girchenko, P, Tuovinen, S, Sammallahti, S, Reynolds, RM, Lahti, J et al.. Maternal Hypertensive Pregnancy Disorders and Mental Disorders in Children. Hypertension. 2020;75 (6):1429-1438. doi: 10.1161/HYPERTENSIONAHA.119.14140. PubMed PMID:32306771 .
  73. Viitasalo, L, Iltanen, S, Huhtala, H, Saavalainen, P, Kaukinen, K, Lindfors, K et al.. First-degree Relatives of Celiac Disease Patients Have Increased Seroreactivity to Serum Microbial Markers. Nutrients. 2020;12 (4):. doi: 10.3390/nu12041073. PubMed PMID:32294897 PubMed Central PMC7230150.
  74. Alakoski, A, Hervonen, K, Mansikka, E, Reunala, T, Kaukinen, K, Kivelä, L et al.. The Long-Term Safety and Quality of Life Effects of Oats in Dermatitis Herpetiformis. Nutrients. 2020;12 (4):. doi: 10.3390/nu12041060. PubMed PMID:32290504 PubMed Central PMC7230654.
  75. Mars, N, Koskela, JT, Ripatti, P, Kiiskinen, TTJ, Havulinna, AS, Lindbohm, JV et al.. Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers. Nat Med. 2020;26 (4):549-557. doi: 10.1038/s41591-020-0800-0. PubMed PMID:32273609 .
  76. Äärelä, L, Nevalainen, PI, Kurppa, K, Hiltunen, P. First Scandinavian case of successful pregnancy during nitisinone treatment for type 1 tyrosinemia. J Pediatr Endocrinol Metab. 2020;33 (5):661-664. doi: 10.1515/jpem-2019-0540. PubMed PMID:32238608 .
  77. Karvonen, S, Kestilä, L, Rimpelä, A. Accumulated Disadvantage over the Lower Secondary School Years in Helsinki Metropolitan Area, Finland. Int J Environ Res Public Health. 2020;17 (7):. doi: 10.3390/ijerph17072290. PubMed PMID:32235306 PubMed Central PMC7177873.
  78. Kivelä, L, Hekkala, S, Huhtala, H, Kaukinen, K, Kurppa, K. Lack of long-term follow-up after paediatric-adult transition in coeliac disease is not associated with complications, ongoing symptoms or dietary adherence. United European Gastroenterol J. 2020;8 (2):157-166. doi: 10.1177/2050640619900077. PubMed PMID:32213072 PubMed Central PMC7079270.
  79. Karalexi, MA, Dessypris, N, Ma, X, Spector, LG, Marcotte, E, Clavel, J et al.. Age-, sex- and disease subtype-related foetal growth differentials in childhood acute myeloid leukaemia risk: A Childhood Leukemia International Consortium analysis. Eur J Cancer. 2020;130 :1-11. doi: 10.1016/j.ejca.2020.01.018. PubMed PMID:32163883 .
  80. Koivunen, S, Viljakainen, M, Männistö, T, Gissler, M, Pouta, A, Kaaja, R et al.. Pregnancy outcomes according to the definition of gestational diabetes. PLoS One. 2020;15 (3):e0229496. doi: 10.1371/journal.pone.0229496. PubMed PMID:32134959 PubMed Central PMC7058278.
  81. Sane, F, Bertin, A, Sioofy-Khojine, AB, Oikarinen, S, Alidjinou, EK, Veijola, R et al.. Enhancing and neutralizing anti-coxsackievirus activities in serum samples from patients prior to development of type 1 diabetes. Diabetes Metab Res Rev. 2020;36 (6):e3305. doi: 10.1002/dmrr.3305. PubMed PMID:32118346 .
  82. Nikkilä, A, Raitanen, J, Lohi, O, Auvinen, A. Radiation exposure from computerized tomography and risk of childhood leukemia: Finnish register-based case-control study of childhood leukemia (FRECCLE). Haematologica. 2020;105 (3):849-850. doi: 10.3324/haematol.2019.245704. PubMed PMID:32115415 PubMed Central PMC7049358.
  83. Seppälä, EM, Oikarinen, S, Lehtonen, JP, Neupane, S, Honkanen, H, Tyni, I et al.. Association of Picornavirus Infections With Acute Otitis Media in a Prospective Birth Cohort Study. J Infect Dis. 2020;222 (2):324-332. doi: 10.1093/infdis/jiaa087. PubMed PMID:32108877 .
  84. Kröger, S, Kurppa, K, Repo, M, Huhtala, H, Kaukinen, K, Lindfors, K et al.. Severity of Villous Atrophy at Diagnosis in Childhood Does Not Predict Long-term Outcomes in Celiac Disease. J Pediatr Gastroenterol Nutr. 2020;71 (1):71-77. doi: 10.1097/MPG.0000000000002675. PubMed PMID:32097370 .
  85. Kortesoja, L, Vainikainen, MP, Hotulainen, R, Rimpelä, A, Dobewall, H, Lindfors, P et al.. Bidirectional Relationship of Sleep with Emotional and Behavioral Difficulties: A Five-year Follow-up of Finnish Adolescents. J Youth Adolesc. 2020;49 (6):1277-1291. doi: 10.1007/s10964-020-01203-3. PubMed PMID:32086723 PubMed Central PMC7237401.
  86. Sankari, H, Hietikko, M, Kurppa, K, Kaukinen, K, Mansikka, E, Huhtala, H et al.. Intestinal TG3- and TG2-Specific Plasma Cell Responses in Dermatitis Herpetiformis Patients Undergoing a Gluten Challenge. Nutrients. 2020;12 (2):. doi: 10.3390/nu12020467. PubMed PMID:32069794 PubMed Central PMC7071213.
  87. Isosävi, S, Diab, SY, Qouta, S, Kangaslampi, S, Sleed, M, Kankaanpää, S et al.. Caregiving representations in war conditions: Associations with maternal trauma, mental health, and mother-infant interaction. Infant Ment Health J. 2020;41 (2):246-263. doi: 10.1002/imhj.21841. PubMed PMID:32057130 .
  88. Sen, P, Dickens, AM, López-Bascón, MA, Lindeman, T, Kemppainen, E, Lamichhane, S et al.. Metabolic alterations in immune cells associate with progression to type 1 diabetes. Diabetologia. 2020;63 (5):1017-1031. doi: 10.1007/s00125-020-05107-6. PubMed PMID:32043185 PubMed Central PMC7145788.
  89. Kalliokoski, S, Mansikka, E, de Kauwe, A, Huhtala, H, Saavalainen, P, Kurppa, K et al.. Gliadin-Induced Ex Vivo T-Cell Response in Dermatitis Herpetiformis: A Predictor of Clinical Relapse on Gluten Challenge?. J Invest Dermatol. 2020;140 (9):1867-1869.e2. doi: 10.1016/j.jid.2019.12.038. PubMed PMID:32035923 .
  90. Grönroos, T, Mäkinen, A, Laukkanen, S, Mehtonen, J, Nikkilä, A, Oksa, L et al.. Clinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia. Sci Rep. 2020;10 (1):2043. doi: 10.1038/s41598-020-58970-z. PubMed PMID:32029838 PubMed Central PMC7005266.
  91. Li, Q, Parikh, H, Butterworth, MD, Lernmark, Å, Hagopian, W, Rewers, M et al.. Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study. Diabetes. 2020;69 (3):465-476. doi: 10.2337/db19-0756. PubMed PMID:32029481 PubMed Central PMC7034190.
  92. Parajuli, A, Hui, N, Puhakka, R, Oikarinen, S, Grönroos, M, Selonen, VAO et al.. Yard vegetation is associated with gut microbiota composition. Sci Total Environ. 2020;713 :136707. doi: 10.1016/j.scitotenv.2020.136707. PubMed PMID:32019041 .
  93. Kortekangas, E, Kamng’ona, AW, Fan, YM, Cheung, YB, Ashorn, U, Matchado, A et al.. Environmental exposures and child and maternal gut microbiota in rural Malawi. Paediatr Perinat Epidemiol. 2020;34 (2):161-170. doi: 10.1111/ppe.12623. PubMed PMID:32011017 PubMed Central PMC7154550.
  94. Girchenko, P, Lahti-Pulkkinen, M, Heinonen, K, Reynolds, RM, Laivuori, H, Lipsanen, J et al.. Persistently High Levels of Maternal Antenatal Inflammation Are Associated With and Mediate the Effect of Prenatal Environmental Adversities on Neurodevelopmental Delay in the Offspring. Biol Psychiatry. 2020;87 (10):898-907. doi: 10.1016/j.biopsych.2019.12.004. PubMed PMID:31987493 .
  95. Satterstrom, FK, Kosmicki, JA, Wang, J, Breen, MS, De Rubeis, S, An, JY et al.. Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism. Cell. 2020;180 (3):568-584.e23. doi: 10.1016/j.cell.2019.12.036. PubMed PMID:31981491 PubMed Central PMC7250485.
  96. Saarinen, NVV, Stone, VM, Hankaniemi, MM, Mazur, MA, Vuorinen, T, Flodström-Tullberg, M et al.. Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection. Viruses. 2020;12 (1):. doi: 10.3390/v12010078. PubMed PMID:31936473 PubMed Central PMC7020046.
  97. Repo, M, Rajalahti, T, Hiltunen, P, Sotka, A, Kivelä, L, Huhtala, H et al.. Diagnostic findings and long-term prognosis in children with anemia undergoing GI endoscopies. Gastrointest Endosc. 2020;91 (6):1272-1281.e2. doi: 10.1016/j.gie.2019.12.042. PubMed PMID:31917169 .
  98. Miettinen, ME, Niinistö, S, Erlund, I, Cuthbertson, D, Nucci, AM, Honkanen, J et al.. Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study. Diabetologia. 2020;63 (4):780-787. doi: 10.1007/s00125-019-05077-4. PubMed PMID:31912198 PubMed Central PMC7054378.
  99. Kamng’ona, AW, Young, R, Arnold, CD, Patson, N, Jorgensen, JM, Kortekangas, E et al.. Provision of Lipid-Based Nutrient Supplements to Mothers During Pregnancy and 6 Months Postpartum and to Their Infants from 6 to 18 Months Promotes Infant Gut Microbiota Diversity at 18 Months of Age but Not Microbiota Maturation in a Rural Malawian Setting: Secondary Outcomes of a Randomized Trial. J Nutr. 2020;150 (4):918-928. doi: 10.1093/jn/nxz298. PubMed PMID:31909811 PubMed Central PMC7138685.
  100. Gustafsson, I, Repo, M, Popp, A, Kaukinen, K, Hiltunen, P, Arvola, T et al.. Prevalence and diagnostic outcomes of children with duodenal lesions and negative celiac serology. Dig Liver Dis. 2020;52 (3):289-295. doi: 10.1016/j.dld.2019.11.011. PubMed PMID:31899123 .
  101. Liu, X, Vehik, K, Huang, Y, Elding Larsson, H, Toppari, J, Ziegler, AG et al.. Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study. Diabetes Care. 2020;43 (3):556-562. doi: 10.2337/dc19-1670. PubMed PMID:31896601 PubMed Central PMC7035588.
  102. Suokas, K, Koivisto, AM, Hakulinen, C, Kaltiala, R, Sund, R, Lumme, S et al.. Association of Income With the Incidence Rates of First Psychiatric Hospital Admissions in Finland, 1996-2014. JAMA Psychiatry. 2020;77 (3):274-284. doi: 10.1001/jamapsychiatry.2019.3647. PubMed PMID:31851325 PubMed Central PMC6990744.
  103. Ojwang, V, Nwaru, BI, Takkinen, HM, Kaila, M, Niemelä, O, Haapala, AM et al.. Early exposure to cats, dogs and farm animals and the risk of childhood asthma and allergy. Pediatr Allergy Immunol. 2020;31 (3):265-272. doi: 10.1111/pai.13186. PubMed PMID:31829464 .
  104. Olsen, MF, Iuel-Brockdorff, AS, Yaméogo, CW, Cichon, B, Fabiansen, C, Filteau, S et al.. Early development in children with moderate acute malnutrition: A cross-sectional study in Burkina Faso. Matern Child Nutr. 2020;16 (2):e12928. doi: 10.1111/mcn.12928. PubMed PMID:31823490 PubMed Central PMC7083399.
  105. Rinta-Kokko, H, Auranen, K, Toropainen, M, Nuorti, JP, Nohynek, H, Siira, L et al.. Effectiveness of 10-valent pneumococcal conjugate vaccine estimated with three parallel study designs among vaccine-eligible children in Finland. Vaccine. 2020;38 (6):1559-1564. doi: 10.1016/j.vaccine.2019.11.049. PubMed PMID:31791813 .
  106. Nikkilä, A, Arvela, H, Mehtonen, J, Raitanen, J, Heinäniemi, M, Lohi, O et al.. Predicting residential radon concentrations in Finland: Model development, validation, and application to childhood leukemia. Scand J Work Environ Health. 2020;46 (3):278-292. doi: 10.5271/sjweh.3867. PubMed PMID:31763683 .
  107. Kaltiala, R, Heino, E, Työläjärvi, M, Suomalainen, L. Adolescent development and psychosocial functioning after starting cross-sex hormones for gender dysphoria. Nord J Psychiatry. 2020;74 (3):213-219. doi: 10.1080/08039488.2019.1691260. PubMed PMID:31762394 .
  108. Lindfors, K, Lin, J, Lee, HS, Hyöty, H, Nykter, M, Kurppa, K et al.. Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study. Gut. 2020;69 (8):1416-1422. doi: 10.1136/gutjnl-2019-319809. PubMed PMID:31744911 PubMed Central PMC7234892.
  109. Schreuders, M, van den Putte, B, Mlinarić, M, Mélard, N, Perelman, J, Richter, M et al.. The Association Between Smoke-Free School Policies and Adolescents’ Perceived Antismoking Norms: Moderation by School Connectedness. Nicotine Tob Res. 2020;22 (11):1964-1972. doi: 10.1093/ntr/ntz212. PubMed PMID:31723975 PubMed Central PMC7593364.
  110. Stewart, CP, Wessells, KR, Arnold, CD, Huybregts, L, Ashorn, P, Becquey, E et al.. Lipid-based nutrient supplements and all-cause mortality in children 6-24 months of age: a meta-analysis of randomized controlled trials. Am J Clin Nutr. 2020;111 (1):207-218. doi: 10.1093/ajcn/nqz262. PubMed PMID:31697329 .
  111. Mahfuz, M, Alam, MA, Das, S, Fahim, SM, Hossain, MS, Petri, WA Jr et al.. Daily Supplementation With Egg, Cow Milk, and Multiple Micronutrients Increases Linear Growth of Young Children with Short Stature. J Nutr. 2020;150 (2):394-403. doi: 10.1093/jn/nxz253. PubMed PMID:31665385 .
  112. Harjula, SE, Saralahti, AK, Ojanen, MJT, Rantapero, T, Uusi-Mäkelä, MIE, Nykter, M et al.. Characterization of immune response against Mycobacterium marinum infection in the main hematopoietic organ of adult zebrafish (Danio rerio). Dev Comp Immunol. 2020;103 :103523. doi: 10.1016/j.dci.2019.103523. PubMed PMID:31626817 .
  113. Adu-Afarwuah, S, Young, RR, Lartey, A, Okronipa, H, Ashorn, P, Ashorn, U et al.. Supplementation with Small-Quantity Lipid-Based Nutrient Supplements Does Not Increase Child Morbidity in a Semiurban Setting in Ghana: A Secondary Outcome Noninferiority Analysis of the International Lipid-Based Nutrient Supplements (iLiNS)-DYAD Randomized Controlled Trial. J Nutr. 2020;150 (2):382-393. doi: 10.1093/jn/nxz243. PubMed PMID:31603205 PubMed Central PMC7722352.
  114. Dobewall, H, Koivusilta, L, Karvonen, S, Lindfors, P, Kinnunen, JM, Vainikainen, MP et al.. Late start of upper secondary education and health-compromising behaviours among Finnish adolescents-a follow-up study. Eur J Public Health. 2020;30 (3):438-443. doi: 10.1093/eurpub/ckz178. PubMed PMID:31598643 PubMed Central PMC7292345.
  115. Husby, S, Koletzko, S, Korponay-Szabó, I, Kurppa, K, Mearin, ML, Ribes-Koninckx, C et al.. European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020. J Pediatr Gastroenterol Nutr. 2020;70 (1):141-156. doi: 10.1097/MPG.0000000000002497. PubMed PMID:31568151 .
  116. Kaltiala, R, Bergman, H, Carmichael, P, de Graaf, NM, Egebjerg Rischel, K, Frisén, L et al.. Time trends in referrals to child and adolescent gender identity services: a study in four Nordic countries and in the UK. Nord J Psychiatry. 2020;74 (1):40-44. doi: 10.1080/08039488.2019.1667429. PubMed PMID:31556776 .
  117. Leão, T, Perelman, J, Clancy, L, Hoffmann, L, Kinnunen, JM, Mélard, N et al.. Cost of youth tobacco-control policies in seven European countries. Eur J Public Health. 2020;30 (2):374-379. doi: 10.1093/eurpub/ckz150. PubMed PMID:31535140 PubMed Central PMC7183368.
  118. Raisamo, S, Kinnunen, JM, Pere, L, Lindfors, P, Rimpelä, A. Adolescent Gambling, Gambling Expenditure and Gambling-Related Harms in Finland, 2011-2017. J Gambl Stud. 2020;36 (2):597-610. doi: 10.1007/s10899-019-09892-7. PubMed PMID:31520272 PubMed Central PMC7214496.
  119. Lahti-Pulkkinen, M, Girchenko, P, Robinson, R, Lehto, SM, Toffol, E, Heinonen, K et al.. Maternal depression and inflammation during pregnancy. Psychol Med. 2020;50 (11):1839-1851. doi: 10.1017/S0033291719001909. PubMed PMID:31439060 .
  120. Provençal, N, Arloth, J, Cattaneo, A, Anacker, C, Cattane, N, Wiechmann, T et al.. Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation. Proc Natl Acad Sci U S A. 2020;117 (38):23280-23285. doi: 10.1073/pnas.1820842116. PubMed PMID:31399550 PubMed Central PMC7519233.
  121. Kakko, K, Pihlakoski, L, Keskinen, P, Salmelin, R, Puura, K. Current follow-up practices often fail to detect metabolic and neurological adverse reactions in children treated with second-generation antipsychotics. Acta Paediatr. 2020;109 (2):342-348. doi: 10.1111/apa.14951. PubMed PMID:31359492 .
  122. Leão, T, Perelman, J, Clancy, L, Mlinarić, M, Kinnunen, JM, Nuyts, PAW et al.. Economic Evaluation of Five Tobacco Control Policies Across Seven European Countries. Nicotine Tob Res. 2020;22 (7):1202-1209. doi: 10.1093/ntr/ntz124. PubMed PMID:31350556 PubMed Central PMC7291799.
  123. Heikkilä, P, Kokko, P, Lohi, O, Korppi, M. Nursing intensity scores did not correlate well with reimbursement claims for infant bronchiolitis. Acta Paediatr. 2020;109 (1):140-146. doi: 10.1111/apa.14926. PubMed PMID:31269265 .
  124. Timberlake, DS, Laitinen, U, Kinnunen, JM, Rimpela, AH. Strategies and barriers to achieving the goal of Finland’s tobacco endgame. Tob Control. 2020;29 (4):398-404. doi: 10.1136/tobaccocontrol-2018-054779. PubMed PMID:31152117 PubMed Central PMC7361028.
  125. Doku, DT, Acacio-Claro, PJ, Koivusilta, L, Rimpelä, A. Social determinants of adolescent smoking over three generations. Scand J Public Health. 2020;48 (6):646-656. doi: 10.1177/1403494819839854. PubMed PMID:30973093 .
  126. Wolford, E, Lahti-Pulkkinen, M, Girchenko, P, Lipsanen, J, Tuovinen, S, Lahti, J et al.. Associations of antenatal glucocorticoid exposure with mental health in children. Psychol Med. 2020;50 (2):247-257. doi: 10.1017/S0033291718004129. PubMed PMID:30688183 .

Search PubMed