Skip to content
Tampere Pancreas Group

Publications

2024

  1. Selänne, L, Haijanen, J, Sippola, S, Hurme, S, Rautio, T, Nordström, P et al.. Three-Year Outcomes of Oral Antibiotics vs Intravenous and Oral Antibiotics for Uncomplicated Acute Appendicitis: A Secondary Analysis of the APPAC II Randomized Clinical Trial. JAMA Surg. 2024; :. doi: 10.1001/jamasurg.2023.5947. PubMed PMID:38630471 PubMed Central PMC11024776.
  2. Tiainen, E, Wirta, EV, Tyrväinen, T, Kuorilehto, T, Toikkanen, V, Laukkarinen, J et al.. Calcifications in the descending thoracic aorta predict postoperative anastomotic leakages after esophagectomy for cancer. World J Surg. 2024; :. doi: 10.1002/wjs.12133. PubMed PMID:38470437 .
  3. Luomajoki, J, Mattila, L, Laukkarinen, J, Ukkonen, M. Long-Term Outcomes following Acute Upper Gastrointestinal Bleeding Remain Poor: A Single-Center Comparison over Two Distinct Time Periods within the Last 15 Years in Finland. Visc Med. 2024;40 (1):30-38. doi: 10.1159/000535061. PubMed PMID:38312369 PubMed Central PMC10836953.
  4. Aronen, A, Aittoniemi, J, Huttunen, R, Siiki, A, Antila, A, Sand, J et al.. P-suPAR may reflect the inflammatory response after pancreatic surgery. Pancreatology. 2024;24 (1):146-151. doi: 10.1016/j.pan.2023.11.006. PubMed PMID:38000982 .

Search PubMed

2023

  1. Aronen, A, Aittoniemi, J, Huttunen, R, Siiki, A, Antila, A, Sand, J et al.. P-suPAR may reflect the inflammatory response after pancreatic surgery. Pancreatology. 2024;24 (1):146-151. doi: 10.1016/j.pan.2023.11.006. PubMed PMID:38000982 .
  2. Parhiala, M, Nøjgaard, C, Bartholdy, A, Waage, A, Ignatavičius, P, Engjom, T et al.. Quality of life after endoscopic procedures for chronic pancreatitis: A multicentre study. United European Gastroenterol J. 2023;11 (9):884-893. doi: 10.1002/ueg2.12466. PubMed PMID:37812591 PubMed Central PMC10637126.
  3. Siiki, A, Antila, A, Vaalavuo, Y, Ronkainen, J, Rinta-Kiikka, I, Laukkarinen, J et al.. Unconventional treatment of inoperable biliary IPMN with an oesophageal stent in the common bile duct: case report. Ther Adv Gastrointest Endosc. 2023;16 :26317745231183311. doi: 10.1177/26317745231183311. PubMed PMID:37533690 PubMed Central PMC10392209.
  4. Levink, IJM, Jaarsma, SC, Koopmann, BDM, van Riet, PA, Overbeek, KA, Meziani, J et al.. The additive value of CA19.9 monitoring in a pancreatic cyst surveillance program. United European Gastroenterol J. 2023;11 (7):601-611. doi: 10.1002/ueg2.12422. PubMed PMID:37435855 PubMed Central PMC10493362.
  5. Kolehmainen, CSJ, Ukkonen, MT, Tomminen, T, Helavirta, IM, Laukkarinen, JM, Hyöty, M et al.. Short learning curve in transition from laparoscopic to robotic-assisted rectal cancer surgery: a prospective study from a Finnish Tertiary Referral Centre. J Robot Surg. 2023;17 (5):2361-2367. doi: 10.1007/s11701-023-01626-7. PubMed PMID:37421570 PubMed Central PMC10492689.
  6. Siiki, A, Ahola, R, Vaalavuo, Y, Antila, A, Laukkarinen, J. Initial management of suspected biliary injury after laparoscopic cholecystectomy. World J Gastrointest Surg. 2023;15 (4):592-599. doi: 10.4240/wjgs.v15.i4.592. PubMed PMID:37206082 PubMed Central PMC10190719.
  7. Vaalavuo, Y, Vornanen, M, Ahola, R, Antila, A, Rinta-Kiikka, I, Sand, J et al.. Long-term (10-year) outcomes and prognostic factors in resected intraductal papillary mucinous neoplasm tumors in Finland: A nationwide retrospective study. Surgery. 2023;174 (1):75-82. doi: 10.1016/j.surg.2023.02.006. PubMed PMID:37062604 .
  8. Parhiala, M, Ukkonen, M, Sand, J, Laukkarinen, J. Osteoporosis and sarcopenia are common and insufficiently diagnosed among chronic pancreatitis patients. BMC Gastroenterol. 2023;23 (1):124. doi: 10.1186/s12876-023-02756-w. PubMed PMID:37046204 PubMed Central PMC10099896.
  9. Argandykov, D, Dorken-Gallastegi, A, El Moheb, M, Gebran, A, Proaño-Zamudio, JA, Bokenkamp, M et al.. Is perioperative COVID-19 really associated with worse surgical outcomes? A nationwide COVIDSurg propensity-matched analysis. J Trauma Acute Care Surg. 2023;94 (4):513-524. doi: 10.1097/TA.0000000000003859. PubMed PMID:36949053 PubMed Central PMC10044588.
  10. Laitamäki, M, Piili, RP, Laukkarinen, J, Ukkonen, M. Palliative gastrointestinal surgical oncology-outcomes after palliative care consultation: retrospective observational study. BMJ Support Palliat Care. 2023; :. doi: 10.1136/spcare-2022-004045. PubMed PMID:36854612 .
  11. Vu Trung, K, Abou-Ali, E, Caillol, F, Paik, WH, Napoleon, B, Masaryk, V et al.. Endoscopic papillectomy for ampullary lesions in patients with familial adenomatous polyposis compared with sporadic lesions: a propensity score-matched cohort. Endoscopy. 2023;55 (8):709-718. doi: 10.1055/a-2029-2935. PubMed PMID:36746390 .
  12. Aronen, A, Aittoniemi, J, Huttunen, R, Nikkola, A, Nikkola, J, Limnell, O et al.. Plasma soluble urokinase-type plasminogen activator receptor (P-suPAR) in the diagnostics between malignant and non-malignant pancreatic lesions. Pancreatology. 2023;23 (2):213-217. doi: 10.1016/j.pan.2022.12.012. PubMed PMID:36596714 .
  13. Parhiala, M, Waage, A, Ignatavičius, P, Olesen, SS, Poulsen, JL, Trond, E et al.. Surgical strategies for chronic pancreatitis in a 1,327- patient Scandinavian Baltic pancreatic Club (SBPC) register. Pancreatology. 2023;23 (1):28-34. doi: 10.1016/j.pan.2022.12.004. PubMed PMID:36543740 .
  14. Kivivuori, A, Mattila, L, Siiki, A, Laukkarinen, J, Rantanen, T, Ukkonen, M et al.. Wait-and-see strategy is justified after ERCP and endoscopic sphincterotomy in elderly patients with common biliary duct stones. J Trauma Acute Care Surg. 2023;94 (3):443-447. doi: 10.1097/TA.0000000000003852. PubMed PMID:36524923 .
  15. Mönttinen, T, Kangaspunta, H, Laukkarinen, J, Ukkonen, M. Routine use of laparoscopic techniques in daily practice improves outcomes after appendectomy. Eur J Trauma Emerg Surg. 2023;49 (4):1763-1769. doi: 10.1007/s00068-022-02125-4. PubMed PMID:36261733 PubMed Central PMC10449719.
  16. Tamburrino, D, Cortesi, P, Facchetti, R, de Pretis, N, Pérez-Cuadrado-Robles, E, Uribarri-Gonzalez, L et al.. Real-world costs and dynamics of surveillance in patients who underwent surgery for low-risk branch duct intraductal papillary mucinous neoplasms. Eur J Surg Oncol. 2023;49 (1):137-141. doi: 10.1016/j.ejso.2022.08.033. PubMed PMID:36085119 .

Search PubMed

2022
  1. Aronen, A, Aittoniemi, J, Huttunen, R, Nikkola, A, Nikkola, J, Limnell, O et al.. Plasma soluble urokinase-type plasminogen activator receptor (P-suPAR) in the diagnostics between malignant and non-malignant pancreatic lesions. Pancreatology. 2023;23 (2):213-217. doi: 10.1016/j.pan.2022.12.012. PubMed PMID:36596714 .
  2. Nikkola, A, Mäkelä, KA, Herzig, KH, Mutt, SJ, Prasannan, A, Seppänen, H et al.. Pancreatic Secretory Trypsin Inhibitor (SPINK1) Gene Mutation in Patients with Acute Alcohol Pancreatitis (AAP) Compared to Healthy Controls and Heavy Alcohol Users without Pancreatitis. Int J Mol Sci. 2022;23 (24):. doi: 10.3390/ijms232415726. PubMed PMID:36555366 PubMed Central PMC9778821.
  3. Parhiala, M, Waage, A, Ignatavičius, P, Olesen, SS, Poulsen, JL, Trond, E et al.. Surgical strategies for chronic pancreatitis in a 1,327- patient Scandinavian Baltic pancreatic Club (SBPC) register. Pancreatology. 2023;23 (1):28-34. doi: 10.1016/j.pan.2022.12.004. PubMed PMID:36543740 .
  4. Kivivuori, A, Mattila, L, Siiki, A, Laukkarinen, J, Rantanen, T, Ukkonen, M et al.. Wait-and-see strategy is justified after ERCP and endoscopic sphincterotomy in elderly patients with common biliary duct stones. J Trauma Acute Care Surg. 2023;94 (3):443-447. doi: 10.1097/TA.0000000000003852. PubMed PMID:36524923 .
  5. Teränen, V, Nissinen, S, Roine, A, Antila, A, Siiki, A, Vaalavuo, Y et al.. Bile-volatile organic compounds in the diagnostics of pancreatic cancer and biliary obstruction: A prospective proof-of-concept study. Front Oncol. 2022;12 :918539. doi: 10.3389/fonc.2022.918539. PubMed PMID:36479080 PubMed Central PMC9720309.
  6. Mönttinen, T, Kangaspunta, H, Laukkarinen, J, Ukkonen, M. Routine use of laparoscopic techniques in daily practice improves outcomes after appendectomy. Eur J Trauma Emerg Surg. 2023;49 (4):1763-1769. doi: 10.1007/s00068-022-02125-4. PubMed PMID:36261733 PubMed Central PMC10449719.
  7. Tamburrino, D, Cortesi, P, Facchetti, R, de Pretis, N, Pérez-Cuadrado-Robles, E, Uribarri-Gonzalez, L et al.. Real-world costs and dynamics of surveillance in patients who underwent surgery for low-risk branch duct intraductal papillary mucinous neoplasms. Eur J Surg Oncol. 2023;49 (1):137-141. doi: 10.1016/j.ejso.2022.08.033. PubMed PMID:36085119 .
  8. Saaristo, L, Ukkonen, MT, Wirta, EV, Kotaluoto, S, Lammi, M, Laukkarinen, JM et al.. Computer-generated structured electronic medical records are preferable to conventional medical records for patients with acute abdominal pain – a prospective, double-blinded study. J Med Syst. 2022;46 (10):63. doi: 10.1007/s10916-022-01852-w. PubMed PMID:36008740 PubMed Central PMC9411218.
  9. Erchinger, F, Tjora, E, Nordaas, IK, Dimcevski, G, Olesen, SS, Jensen, N et al.. Pancreatic enzyme treatment in chronic pancreatitis: Quality of management and adherence to guidelines-A cross-sectional observational study. United European Gastroenterol J. 2022;10 (8):844-853. doi: 10.1002/ueg2.12276. PubMed PMID:35981311 PubMed Central PMC9557959.
  10. Laitamäki, M, Tyrväinen, T, Lehto, JT, Laukkarinen, J, Ukkonen, M. Endoscopic duodenal stenting is efficient, but has higher rate of reoperations than gastrojejunostomy in palliative treatment for gastric outlet obstruction. Langenbecks Arch Surg. 2022;407 (6):2509-2515. doi: 10.1007/s00423-022-02565-x. PubMed PMID:35648229 PubMed Central PMC9468122.
  11. Salminen, P, Sippola, S, Haijanen, J, Nordström, P, Rantanen, T, Rautio, T et al.. Antibiotics versus placebo in adults with CT-confirmed uncomplicated acute appendicitis (APPAC III): randomized double-blind superiority trial. Br J Surg. 2022;109 (6):503-509. doi: 10.1093/bjs/znac086. PubMed PMID:35576384 PubMed Central PMC10364767.
  12. Tamburrino, D, de Pretis, N, Pérez-Cuadrado-Robles, E, Uribarri-Gonzalez, L, Ateeb, Z, Belfiori, G et al.. Identification of patients with branch-duct intraductal papillary mucinous neoplasm and very low risk of cancer: multicentre study. Br J Surg. 2022;109 (7):617-622. doi: 10.1093/bjs/znac103. PubMed PMID:35511697 PubMed Central PMC10364743.
  13. Ahola, R, Siiki, A, Rinta-Kiikka, I, Laitinen, I, Antila, A, Jämsen, E et al.. Preoperative measures predicting outcome after pancreatic resection in aged patients. Scand J Surg. 2022;111 (1):14574969221083136. doi: 10.1177/14574969221083136. PubMed PMID:35333104 .
  14. Erchinger, F, Engjom, T, Dimcevski, G, Drewes, AM, Olesen, SS, Vujasinovic, M et al.. Exocrine pancreas insufficiency in chronic pancreatitis – Risk factors and associations with complications. A multicentre study of 1869 patients. Pancreatology. 2022;22 (3):374-380. doi: 10.1016/j.pan.2022.02.003. PubMed PMID:35216905 .

Search PubMed

2021
  1. Parhiala, M, Sand, J, Laukkarinen, J. Surgery for chronic pancreatitis in Finland is rare but seems to produce good long-term results. World J Clin Cases. 2021;9 (35):10927-10936. doi: 10.12998/wjcc.v9.i35.10927. PubMed PMID:35047603 PubMed Central PMC8678871.
  2. Hitchman, L, Machin, M, COVIDSurg Collaborative and Vascular and Endovascular Research Network. Impact of COVID-19 on vascular patients worldwide: analysis of the COVIDSurg data. J Cardiovasc Surg (Torino). 2021;62 (6):558-570. doi: 10.23736/S0021-9509.21.12024-5. PubMed PMID:35037445 .
  3. Peltola, E, Hannula, P, Huhtala, H, Metso, S, Sand, J, Laukkarinen, J et al.. Long-term morbidity and mortality in patients diagnosed with an insulinoma. Eur J Endocrinol. 2021;185 (4):577-586. doi: 10.1530/EJE-21-0230. PubMed PMID:34374651 PubMed Central PMC8784472.
  4. Tahkola, K, Ahtiainen, M, Mecklin, JP, Kellokumpu, I, Laukkarinen, J, Tammi, M et al.. Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer. Sci Rep. 2021;11 (1):12216. doi: 10.1038/s41598-021-91796-x. PubMed PMID:34108626 PubMed Central PMC8190291.
  5. Teränen, V, Rinta-Kiikka, I, Holli-Helenius, K, Laaninen, M, Sand, J, Laukkarinen, J et al.. Perioperative acinar cell count method works well in the prediction of postoperative pancreatic fistula and other postoperative complications after pancreaticoduodenectomy. Pancreatology. 2021;21 (2):487-493. doi: 10.1016/j.pan.2021.01.005. PubMed PMID:33531257 .
  6. Bläuer, M, Sand, J, Laukkarinen, J. Regulation of p38 MAPK and glucocorticoid receptor activation by hydrocortisone in mono-and co-cultured pancreatic acinar and stellate cells. Pancreatology. 2021;21 (2):384-389. doi: 10.1016/j.pan.2020.12.024. PubMed PMID:33454208 .
  7. Sippola, S, Haijanen, J, Grönroos, J, Rautio, T, Nordström, P, Rantanen, T et al.. Effect of Oral Moxifloxacin vs Intravenous Ertapenem Plus Oral Levofloxacin for Treatment of Uncomplicated Acute Appendicitis: The APPAC II Randomized Clinical Trial. JAMA. 2021;325 (4):353-362. doi: 10.1001/jama.2020.23525. PubMed PMID:33427870 PubMed Central PMC7802006.
  8. Laukkarinen, J. Commentary on: Postoperative acute pancreatitis. Surgery. 2021;169 (4):742-743. doi: 10.1016/j.surg.2020.10.020. PubMed PMID:33293030 .
  9. Aronen, A, Aittoniemi, J, Huttunen, R, Nikkola, A, Rinta-Kiikka, I, Nikkola, J et al.. Plasma suPAR may help to distinguish between chronic pancreatitis and pancreatic cancer. Scand J Gastroenterol. 2021;56 (1):81-85. doi: 10.1080/00365521.2020.1849383. PubMed PMID:33245246 .
  10. Peltola, E, Hannula, P, Huhtala, H, Sintonen, H, Metso, S, Sand, J et al.. Long-term health-related quality of life in persons diagnosed with an insulinoma in Finland 1980-2010. Clin Endocrinol (Oxf). 2021;94 (2):250-257. doi: 10.1111/cen.14336. PubMed PMID:32974918 .
  11. Tahkola, K, Ahtiainen, M, Kellokumpu, I, Mecklin, JP, Laukkarinen, J, Laakkonen, J et al.. Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer. Virchows Arch. 2021;478 (2):209-217. doi: 10.1007/s00428-020-02888-4. PubMed PMID:32676968 PubMed Central PMC7969575.

Search PubMed

2020
  1. Laukkarinen, J. Commentary on: Postoperative acute pancreatitis. Surgery. 2021;169 (4):742-743. doi: 10.1016/j.surg.2020.10.020. PubMed PMID:33293030 .
  2. Aronen, A, Aittoniemi, J, Huttunen, R, Nikkola, A, Rinta-Kiikka, I, Nikkola, J et al.. Plasma suPAR may help to distinguish between chronic pancreatitis and pancreatic cancer. Scand J Gastroenterol. 2021;56 (1):81-85. doi: 10.1080/00365521.2020.1849383. PubMed PMID:33245246 .
  3. Peltola, E, Hannula, P, Huhtala, H, Sintonen, H, Metso, S, Sand, J et al.. Long-term health-related quality of life in persons diagnosed with an insulinoma in Finland 1980-2010. Clin Endocrinol (Oxf). 2021;94 (2):250-257. doi: 10.1111/cen.14336. PubMed PMID:32974918 .
  4. Olesen, SS, Nøjgaard, C, Novovic, S, Jensen, NM, Nørregaard, P, Dahl, EE et al.. Pain and aetiological risk factors determine quality of life in patients with chronic pancreatitis, but a brick in the puzzle is missing. Pancreatology. 2020;20 (7):1347-1353. doi: 10.1016/j.pan.2020.09.004. PubMed PMID:32948428 .
  5. Vaalavuo, Y, Siiki, A, Antila, A, Rinta-Kiikka, I, Sand, J, Laukkarinen, J et al.. The European evidence-based guidelines on pancreatic cystic neoplasms (PCN) in clinical practice: The development of relative and absolute indications for surgery during prospective IPMN surveillance. Pancreatology. 2020;20 (7):1393-1398. doi: 10.1016/j.pan.2020.09.003. PubMed PMID:32938553 .
  6. Tahkola, K, Ahtiainen, M, Kellokumpu, I, Mecklin, JP, Laukkarinen, J, Laakkonen, J et al.. Prognostic impact of CD73 expression and its relationship to PD-L1 in patients with radically treated pancreatic cancer. Virchows Arch. 2021;478 (2):209-217. doi: 10.1007/s00428-020-02888-4. PubMed PMID:32676968 PubMed Central PMC7969575.
  7. Saaristo, L, Ukkonen, MT, Laukkarinen, JM, Pauniaho, SK. The rate of short-term revisits after diagnosis of non-specific abdominal pain is similar for surgeons and emergency physicians – results from a single tertiary hospital emergency department. Scand J Trauma Resusc Emerg Med. 2020;28 (1):63. doi: 10.1186/s13049-020-00751-8. PubMed PMID:32611415 PubMed Central PMC7330973.
  8. Abu-El-Haija, M, Anazawa, T, Beilman, GJ, Besselink, MG, Del Chiaro, M, Demir, IE et al.. The role of total pancreatectomy with islet autotransplantation in the treatment of chronic pancreatitis: A report from the International Consensus Guidelines in chronic pancreatitis. Pancreatology. 2020;20 (4):762-771. doi: 10.1016/j.pan.2020.04.005. PubMed PMID:32327370 .
  9. Miao, Y, Lu, Z, Yeo, CJ, Vollmer, CM Jr, Fernandez-Del Castillo, C, Ghaneh, P et al.. Management of the pancreatic transection plane after left (distal) pancreatectomy: Expert consensus guidelines by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 2020;168 (1):72-84. doi: 10.1016/j.surg.2020.02.018. PubMed PMID:32249092 .
  10. Khan, J, Laurikka, J, Laukkarinen, J, Toikkanen, V, Ukkonen, M. The incidence and long-term outcomes of esophageal perforations in Finland between 1996 and 2017 – a national registry-based analysis of 1106 esophageal perforations showing high early and late mortality rates and better outcomes in patients treated at high-volume centers. Scand J Gastroenterol. 2020;55 (4):395-401. doi: 10.1080/00365521.2020.1746392. PubMed PMID:32233883 .
  11. Olesen, SS, Poulsen, JL, Novovic, S, Nøjgaard, C, Kalaitzakis, E, Jensen, NM et al.. Multiple risk factors for diabetes mellitus in patients with chronic pancreatitis: A multicentre study of 1117 cases. United European Gastroenterol J. 2020;8 (4):453-461. doi: 10.1177/2050640620901973. PubMed PMID:32213024 PubMed Central PMC7226693.
  12. Laukkarinen, J, Puolakkainen, P. Pancreas in Focus!. Scand J Surg. 2020;109 (1):3. doi: 10.1177/1457496920911804. PubMed PMID:32192423 .
  13. Parhiala, M, Sand, J, Laukkarinen, J. A population-based study of chronic pancreatitis in Finland: Effects on quality of life. Pancreatology. 2020;20 (3):338-346. doi: 10.1016/j.pan.2020.02.005. PubMed PMID:32147309 .
  14. Kangaspunta, H, Tahkola, K, Wirta, EV, Kotaluoto, S, Laukkarinen, J, Ukkonen, M et al.. Preoperative computed tomography is poor in detecting tumors of the appendix among patients with acute appendicitis: A cohort study of 5,224 appendectomies. J Trauma Acute Care Surg. 2020;88 (3):396-401. doi: 10.1097/TA.0000000000002567. PubMed PMID:32107355 .
  15. Olesen, SS, Kuhlmann, L, Novovic, S, Nøjgaard, C, Kalaitzakis, E, Jensen, NM et al.. Association of multiple patient and disease characteristics with the presence and type of pain in chronic pancreatitis. J Gastroenterol Hepatol. 2020;35 (2):326-333. doi: 10.1111/jgh.14783. PubMed PMID:31314128 .

Search PubMed

2019
  1. Lähdeaho, ML, Scheinin, M, Vuotikka, P, Taavela, J, Popp, A, Laukkarinen, J et al.. Safety and efficacy of AMG 714 in adults with coeliac disease exposed to gluten challenge: a phase 2a, randomised, double-blind, placebo-controlled study. Lancet Gastroenterol Hepatol. 2019;4 (12):948-959. doi: 10.1016/S2468-1253(19)30264-X. PubMed PMID:31494096 .
  2. Olesen, SS, Lisitskaya, MV, Drewes, AM, Novovic, S, Nøjgaard, C, Kalaitzakis, E et al.. Pancreatic calcifications associate with diverse aetiological risk factors in patients with chronic pancreatitis: A multicentre study of 1500 cases. Pancreatology. 2019;19 (7):922-928. doi: 10.1016/j.pan.2019.08.009. PubMed PMID:31462382 .
  3. Olesen, SS, Kuhlmann, L, Novovic, S, Nøjgaard, C, Kalaitzakis, E, Jensen, NM et al.. Association of multiple patient and disease characteristics with the presence and type of pain in chronic pancreatitis. J Gastroenterol Hepatol. 2020;35 (2):326-333. doi: 10.1111/jgh.14783. PubMed PMID:31314128 .
  4. Antila, A, Siiki, A, Sand, J, Laukkarinen, J. Perioperative hydrocortisone treatment reduces postoperative pancreatic fistula rate after open distal pancreatectomy. A randomized placebo-controlled trial. Pancreatology. 2019;19 (5):786-792. doi: 10.1016/j.pan.2019.05.457. PubMed PMID:31153781 .
  5. Aronen, A, Aittoniemi, J, Huttunen, R, Nikkola, A, Nikkola, J, Limnell, O et al.. Plasma level of soluble urokinase plasminogen activator receptor (suPAR) predicts long-term mortality after first acute alcohol-induced pancreatitis. Eur J Intern Med. 2019;64 :72-75. doi: 10.1016/j.ejim.2019.04.007. PubMed PMID:31060962 .
  6. Vaalavuo, Y, Antila, A, Ahola, R, Siiki, A, Vornanen, M, Ukkonen, M et al.. Characteristics and long-term survival of resected pancreatic cystic neoplasms in Finland. The first nationwide retrospective cohort analysis. Pancreatology. 2019;19 (3):456-461. doi: 10.1016/j.pan.2019.02.007. PubMed PMID:30808537 .
  7. Bläuer, M, Laaninen, M, Sand, J, Laukkarinen, J. Wnt/β-catenin signalling plays diverse functions during the process of fibrotic remodelling in the exocrine pancreas. Pancreatology. 2019;19 (2):252-257. doi: 10.1016/j.pan.2019.02.003. PubMed PMID:30792046 .
  8. Olesen, SS, Nøjgaard, C, Poulsen, JL, Haas, SL, Vujasinovic, M, Löhr, M et al.. Chronic Pancreatitis Is Characterized by Distinct Complication Clusters That Associate With Etiological Risk Factors. Am J Gastroenterol. 2019;114 (4):656-664. doi: 10.14309/ajg.0000000000000147. PubMed PMID:30741740 .

Search PubMed

2018
  1. Peltola, E, Hannula, P, Huhtala, H, Metso, S, Kiviniemi, U, Vornanen, M et al.. Characteristics and Outcomes of 79 Patients with an Insulinoma: A Nationwide Retrospective Study in Finland. Int J Endocrinol. 2018;2018 :2059481. doi: 10.1155/2018/2059481. PubMed PMID:30425741 PubMed Central PMC6218736.
  2. Siiki, A, Vaalavuo, Y, Antila, A, Ukkonen, M, Rinta-Kiikka, I, Sand, J et al.. Biodegradable biliary stents preferable to plastic stent therapy in post-cholecystectomy bile leak and avoid second endoscopy. Scand J Gastroenterol. ;53 (10-11):1376-1380. doi: 10.1080/00365521.2018.1518480. PubMed PMID:30394150 .
  3. Sippola, S, Grönroos, J, Sallinen, V, Rautio, T, Nordström, P, Rantanen, T et al.. A randomised placebo-controlled double-blind multicentre trial comparing antibiotic therapy with placebo in the treatment of uncomplicated acute appendicitis: APPAC III trial study protocol. BMJ Open. 2018;8 (11):e023623. doi: 10.1136/bmjopen-2018-023623. PubMed PMID:30391919 PubMed Central PMC6231590.
  4. Siiki, A, Sand, J, Laukkarinen, J. A systematic review of biodegradable biliary stents: promising biocompatibility without stent removal. Eur J Gastroenterol Hepatol. 2018;30 (8):813-818. doi: 10.1097/MEG.0000000000001167. PubMed PMID:29782386 .
  5. Ahola, R, Hölsä, H, Kiskola, S, Ojala, P, Pirttilä, A, Sand, J et al.. Access to radical resections of pancreatic cancer is region-dependent despite the public healthcare system in Finland. J Epidemiol Community Health. 2018;72 (9):803-808. doi: 10.1136/jech-2017-210187. PubMed PMID:29720389 .
  6. European Study Group on Cystic Tumours of the Pancreas. European evidence-based guidelines on pancreatic cystic neoplasms. Gut. 2018;67 (5):789-804. doi: 10.1136/gutjnl-2018-316027. PubMed PMID:29574408PubMed Central PMC5890653.
  7. Siiki, A, Rinta-Kiikka, I, Sand, J, Laukkarinen, J. A pilot study of endoscopically inserted biodegradable biliary stents in the treatment of benign biliary strictures and cystic duct leaks. Gastrointest Endosc. 2018;87 (4):1132-1137. doi: 10.1016/j.gie.2017.10.042. PubMed PMID:29128386 .

Search PubMed

2017
  1. Siiki, A, Laukkarinen, J. Can we prevent post-ERCP pancreatitis?. Duodecim. ;133 (3):267-74. . PubMed PMID:29205025 .
  2. Siiki, A, Rinta-Kiikka, I, Sand, J, Laukkarinen, J. A pilot study of endoscopically inserted biodegradable biliary stents in the treatment of benign biliary strictures and cystic duct leaks. Gastrointest Endosc. 2018;87 (4):1132-1137. doi: 10.1016/j.gie.2017.10.042. PubMed PMID:29128386 .
  3. Ahola, R, Siiki, A, Vasama, K, Vornanen, M, Sand, J, Laukkarinen, J et al.. Patients with resected, histologically re-confirmed pancreatic ductal adenocarcinoma (PDAC) can achieve long-term survival despite T3 tumour or nodal involvement. The Finnish Register Study 2000-2013. Pancreatology. ;17 (5):822-826. doi: 10.1016/j.pan.2017.07.192. PubMed PMID:28789903 .
  4. Siiki, A, Rinta-Kiikka, I, Laukkarinen, J. Author’s response: Endoscopic biodegradable biliary stents in the treatment of benign biliary strictures: First report of clinical use in patients. Dig Endosc. 2017;29 (6):732. doi: 10.1111/den.12911. PubMed PMID:28664637 .
  5. Olesen, SS, Poulsen, JL, Drewes, AM, Frøkjær, JB, Laukkarinen, J, Parhiala, M et al.. The Scandinavian baltic pancreatic club (SBPC) database: design, rationale and characterisation of the study cohort. Scand J Gastroenterol. 2017;52 (8):909-915. doi: 10.1080/00365521.2017.1322138. PubMed PMID:28471312.
  6. Nikkola, J, Laukkarinen, J, Huhtala, H, Sand, J. The Intensity of Brief Interventions in Patients with Acute Alcoholic Pancreatitis Should be Increased, Especially in Young Patients with Heavy Alcohol Consumption. Alcohol Alcohol. 2017;52 (4):453-459. doi: 10.1093/alcalc/agx023. PubMed PMID:28419179 .
  7. Laitinen, I, Sand, J, Peromaa, P, Nordback, I, Laukkarinen, J. Quality of life in patients with pancreatic ductal adenocarcinoma undergoing pancreaticoduodenectomy. Pancreatology. ;17 (3):445-450. doi: 10.1016/j.pan.2017.02.013. PubMed PMID:28274687 .
  8. Nikkola, J, Laukkarinen, J, Lahtela, J, Seppänen, H, Järvinen, S, Nordback, I et al.. The Long-term Prospective Follow-up of Pancreatic Function After the First Episode of Acute Alcoholic Pancreatitis: Recurrence Predisposes One to Pancreatic Dysfunction and Pancreatogenic Diabetes. J Clin Gastroenterol. 2017;51 (2):183-190. doi: 10.1097/MCG.0000000000000564. PubMed PMID:28060789 .
  9. Nikkola, A, Aittoniemi, J, Huttunen, R, Rajala, L, Nordback, I, Sand, J et al.. Plasma Level of Soluble Urokinase-type Plasminogen Activator Receptor Predicts the Severity of Acute Alcohol Pancreatitis. Pancreas. 2017;46 (1):77-82. doi: 10.1097/MPA.0000000000000730. PubMed PMID:27841794 .
  10. Siiki, A, Rinta-Kiikka, I, Sand, J, Laukkarinen, J. Endoscopic biodegradable biliary stents in the treatment of benign biliary strictures: First report of clinical use in patients. Dig Endosc. 2017;29 (1):118-121. doi: 10.1111/den.12709. PubMed PMID:27514703 .
  11. Pozzi-Mucelli, RM, Rinta-Kiikka, I, Wünsche, K, Laukkarinen, J, Labori, KJ, Ånonsen, K et al.. Pancreatic MRI for the surveillance of cystic neoplasms: comparison of a short with a comprehensive imaging protocol. Eur Radiol. 2017;27 (1):41-50. doi: 10.1007/s00330-016-4377-4. PubMed PMID:27246720.

Search PubMed

2016
  1. Ukkonen, M, Siiki, A, Antila, A, Tyrväinen, T, Sand, J, Laukkarinen, J et al.. Safety and Efficacy of Acute Endoscopic Retrograde Cholangiopancreatography in the Elderly. Dig Dis Sci. 2016;61 (11):3302-3308. doi: 10.1007/s10620-016-4283-2. PubMed PMID:27565508 .
  2. Laaninen, M, Sand, J, Nordback, I, Vasama, K, Laukkarinen, J. Perioperative Hydrocortisone Reduces Major Complications After Pancreaticoduodenectomy: A Randomized Controlled Trial. Ann Surg. 2016;264 (5):696-702. doi: 10.1097/SLA.0000000000001883. PubMed PMID:27429037 .
  3. Nilsson, LN, Keane, MG, Shamali, A, Millastre Bocos, J, Marijinissen van Zanten, M, Antila, A et al.. Nature and management of pancreatic mucinous cystic neoplasm (MCN): A systematic review of the literature. Pancreatology. ;16 (6):1028-1036. doi: 10.1016/j.pan.2016.09.011. PubMed PMID:27681503 .
  4. Siiki, A, Rinta-Kiikka, I, Sand, J, Laukkarinen, J. Endoscopic biodegradable biliary stents in the treatment of benign biliary strictures: First report of clinical use in patients. Dig Endosc. 2017;29 (1):118-121. doi: 10.1111/den.12709. PubMed PMID:27514703 .
  5. Pozzi-Mucelli, RM, Rinta-Kiikka, I, Wünsche, K, Laukkarinen, J, Labori, KJ, Ånonsen, K et al.. Pancreatic MRI for the surveillance of cystic neoplasms: comparison of a short with a comprehensive imaging protocol. Eur Radiol. 2017;27 (1):41-50. doi: 10.1007/s00330-016-4377-4. PubMed PMID:27246720.
  6. Bläuer, M, Laaninen, M, Sand, J, Laukkarinen, J. Reciprocal stimulation of pancreatic acinar and stellate cells in a novel long-term in vitro co-culture model. Pancreatology. ;16 (4):570-7. doi: 10.1016/j.pan.2016.03.012. PubMed PMID:27075041 .
  7. Siiki, A, Jesenofsky, R, Löhr, M, Nordback, I, Kellomäki, M, Gröhn, H et al.. Biodegradable biliary stents have a different effect than covered metal stents on the expression of proteins associated with tissue healing in benign biliary strictures. Scand J Gastroenterol. 2016;51 (7):880-5. doi: 10.3109/00365521.2016.1156153. PubMed PMID:27003149 .
  8. Klionsky, DJ, Abdelmohsen, K, Abe, A, Abedin, MJ, Abeliovich, H, Acevedo Arozena, A et al.. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016;12 (1):1-222. doi: 10.1080/15548627.2015.1100356. PubMed PMID:26799652 PubMed Central PMC4835977.
  9. Ukkonen, M, Karlsson, S, Laukkarinen, J, Rantanen, T, Paajanen, H, Finnsepsis Study Group et al.. Severe Sepsis in Elderly Patients Undergoing Gastrointestinal Surgery-a Prospective Multicenter Follow-up Study of Finnish Intensive Care Units. J Gastrointest Surg. 2016;20 (5):1028-33. doi: 10.1007/s11605-016-3076-4. PubMed PMID:26768009 .

Search PubMed

2015
  1. Bläuer, M, Sand, J, Laukkarinen, J. Physiological and clinically attainable concentrations of 1,25-dihydroxyvitamin D3 suppress proliferation and extracellular matrix protein expression in mouse pancreatic stellate cells. Pancreatology. ;15 (4):366-71. doi: 10.1016/j.pan.2015.05.044. PubMed PMID:26005021 .
  2. Funel, N, Del Chiaro, M, Cahen, DL, Laukkarinen, J. Pancreatic cancer. Gastroenterol Res Pract. 2015;2015 :809036. doi: 10.1155/2015/809036. PubMed PMID:25878661 PubMed Central PMC4387904.
  3. Siiki, A, Rinta-Kiikka, I, Sand, J, Laukkarinen, J. Biodegradable biliary stent in the endoscopic treatment of cystic duct leak after cholecystectomy: the first case report and review of literature. J Laparoendosc Adv Surg Tech A. 2015;25 (5):419-22. doi: 10.1089/lap.2015.0068. PubMed PMID:25853929 .
  4. Manninen, P, Karvonen, AL, Laukkarinen, J, Aitola, P, Huhtala, H, Collin, P et al.. Colorectal cancer and cholangiocarcinoma in patients with primary sclerosing cholangitis and inflammatory bowel disease. Scand J Gastroenterol. 2015;50 (4):423-8. doi: 10.3109/00365521.2014.946085. PubMed PMID:25636976 .
  5. Collin, P, Rinta-Kiikka, I, Räty, S, Laukkarinen, J, Sand, J. Diagnostic workup of liver lesions: too long time with too many examinations. Scand J Gastroenterol. 2015;50 (3):355-9. doi: 10.3109/00365521.2014.999349. PubMed PMID:25578122 .

Search PubMed

2014
  1. Siiki, A, Rinta-Kiikka, I, Koivisto, T, Vasama, K, Sand, J, Laukkarinen, J et al.. Spyglass single-operator peroral cholangioscopy seems promising in the evaluation of primary sclerosing cholangitis-related biliary strictures. Scand J Gastroenterol. 2014;49 (11):1385-90. doi: 10.3109/00365521.2014.940376. PubMed PMID:25259419 .
  2. Laaninen, M, Bläuer, M, Sand, J, Nordback, I, Laukkarinen, J. Difference in Early Activation of NF-κB and MCP-1 in Acinar-Cell-Rich versus Fibrotic Human Pancreas Exposed to Surgical Trauma and Hypoxia. Gastroenterol Res Pract. 2014;2014 :460363. doi: 10.1155/2014/460363. PubMed PMID:25147563PubMed Central PMC4131420.
  3. Antila, A, Sand, J, Nordback, I, Räty, S, Laukkarinen, J. Is Roux-Y binding pancreaticojejunal anastomosis feasible for patients undergoing left pancreatectomy? Results from a prospective randomized trial. Biomed Res Int. 2014;2014 :508714. doi: 10.1155/2014/508714. PubMed PMID:25013787PubMed Central PMC4071807.
  4. Bläuer, M, Sand, J, Nordback, I, Laukkarinen, J. A novel 2-step culture model for long-term in vitro maintenance of human pancreatic acinar cells. Pancreas. 2014;43 (5):762-7. doi: 10.1097/MPA.0000000000000105. PubMed PMID:24927222 .
  5. Hietanen, D, Räty, S, Sand, J, Mäkelä, T, Laukkarinen, J, Collin, P et al.. Liver stiffness measured by transient elastography in patients with acute pancreatitis. Pancreatology. ;14 (2):91-4. doi: 10.1016/j.pan.2014.01.003. PubMed PMID:24650960 .
  6. Hashimoto, D, Bläuer, M, Hirota, M, Ikonen, NH, Sand, J, Laukkarinen, J et al.. Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs. Eur J Cancer. 2014;50 (7):1382-90. doi: 10.1016/j.ejca.2014.01.011. PubMed PMID:24503026 .
  7. Siiki, A, Helminen, M, Sand, J, Laukkarinen, J. Covered self-expanding metal stents may be preferable to plastic stents in the treatment of chronic pancreatitis-related biliary strictures: a systematic review comparing 2 methods of stent therapy in benign biliary strictures. J Clin Gastroenterol. 2014;48 (7):635-43. doi: 10.1097/MCG.0000000000000020. PubMed PMID:24275713 .
  8. Nikkola, J, Rinta-Kiikka, I, Räty, S, Laukkarinen, J, Lappalainen-Lehto, R, Järvinen, S et al.. Pancreatic morphological changes in long-term follow-up after initial episode of acute alcoholic pancreatitis. J Gastrointest Surg. 2014;18 (1):164-70; discussion 170-1. doi: 10.1007/s11605-013-2279-1. PubMed PMID:24002755 .

Search PubMed

2013
  1. Bläuer, M, Sand, J, Laukkarinen, J. Cryopreserved mouse pancreatic acinar cells from long-term explant outgrowth cultures maintain their secretory phenotype after thawing. Pancreatology. ;13 (6):610-4. doi: 10.1016/j.pan.2013.09.006. PubMed PMID:24280578 .
  2. Räty, S, Sand, J, Laukkarinen, J, Vasama, K, Bassi, C, Salvia, R et al.. Cyst fluid SPINK1 may help to differentiate benign and potentially malignant cystic pancreatic lesions. Pancreatology. ;13 (5):530-3. doi: 10.1016/j.pan.2013.06.008. PubMed PMID:24075519 .
  3. Nikkola, J, Rinta-Kiikka, I, Räty, S, Laukkarinen, J, Lappalainen-Lehto, R, Järvinen, S et al.. Pancreatic morphological changes in long-term follow-up after initial episode of acute alcoholic pancreatitis. J Gastrointest Surg. 2014;18 (1):164-70; discussion 170-1. doi: 10.1007/s11605-013-2279-1. PubMed PMID:24002755 .
  4. Nikkola, J, Räty, S, Laukkarinen, J, Seppänen, H, Lappalainen-Lehto, R, Järvinen, S et al.. Abstinence after first acute alcohol-associated pancreatitis protects against recurrent pancreatitis and minimizes the risk of pancreatic dysfunction. Alcohol Alcohol. ;48 (4):483-6. doi: 10.1093/alcalc/agt019. PubMed PMID:23538610 .

Search PubMed

2012
  1. Laukkarinen, J, Sand, J, Nordback, I. The underlying mechanisms: how hypothyroidism affects the formation of common bile duct stones-a review. HPB Surg. 2012;2012 :102825. doi: 10.1155/2012/102825. PubMed PMID:23049165 PubMed Central PMC3459253.
  2. Laaninen, M, Bläuer, M, Vasama, K, Jin, H, Räty, S, Sand, J et al.. The risk for immediate postoperative complications after pancreaticoduodenectomy is increased by high frequency of acinar cells and decreased by prevalent fibrosis of the cut edge of pancreas. Pancreas. 2012;41 (6):957-61. doi: 10.1097/MPA.0b013e3182480b81. PubMed PMID:22699198 .
  3. Nordback, I, Räty, S, Laukkarinen, J, Järvinen, S, Piironen, A, Leppiniemi, J et al.. A novel radiopaque biodegradable stent for pancreatobiliary applications–the first human phase I trial in the pancreas. Pancreatology. ;12 (3):264-71. doi: 10.1016/j.pan.2012.02.016. PubMed PMID:22687383 .

Search PubMed

2011
  1. Bläuer, M, Nordback, I, Sand, J, Laukkarinen, J. A novel explant outgrowth culture model for mouse pancreatic acinar cells with long-term maintenance of secretory phenotype. Eur J Cell Biol. 2011;90 (12):1052-60. doi: 10.1016/j.ejcb.2011.07.004. PubMed PMID:21906833 .
  2. Perides, G, Weiss, ER, Michael, ES, Laukkarinen, JM, Duffield, JS, Steer, ML et al.. TNF-alpha-dependent regulation of acute pancreatitis severity by Ly-6C(hi) monocytes in mice. J Biol Chem. 2011;286 (15):13327-35. doi: 10.1074/jbc.M111.218388. PubMed PMID:21343291 PubMed Central PMC3075679.

Search PubMed

2010
  1. Laukkarinen, J, Sand, J, Nordback, I. [Hypothyroidism is common in bile duct stone patients]. Duodecim. 2010;126 (19):2247-52. . PubMed PMID:21086683.
  2. Perides, G, van Acker, GJ, Laukkarinen, JM, Steer, ML. Experimental acute biliary pancreatitis induced by retrograde infusion of bile acids into the mouse pancreatic duct. Nat Protoc. 2010;5 (2):335-41. doi: 10.1038/nprot.2009.243. PubMed PMID:20134432 .
  3. Laukkarinen, J, Sand, J, Leppiniemi, J, Kellomäki, M, Nordback, I. A novel technique for hepaticojejunostomy for nondilated bile ducts: a purse-string anastomosis with an intra-anastomotic biodegradable biliary stent. Am J Surg. 2010;200 (1):124-30. doi: 10.1016/j.amjsurg.2009.05.012. PubMed PMID:20074696 .
  4. Laukkarinen, J, Sand, J, Autio, V, Nordback, I. Bile duct stone procedures are more frequent in patients with hypothyroidism. A large, registry-based, cohort study in Finland. Scand J Gastroenterol. 2010;45 (1):70-4. doi: 10.3109/00365520903386721. PubMed PMID:20030579 .
  5. Perides, G, Laukkarinen, JM, Vassileva, G, Steer, ML. Biliary acute pancreatitis in mice is mediated by the G-protein-coupled cell surface bile acid receptor Gpbar1. Gastroenterology. 2010;138 (2):715-25. doi: 10.1053/j.gastro.2009.10.052. PubMed PMID:19900448 PubMed Central PMC2819588.

Search PubMed

2009
  1. Perides, G, Laukkarinen, JM, Vassileva, G, Steer, ML. Biliary acute pancreatitis in mice is mediated by the G-protein-coupled cell surface bile acid receptor Gpbar1. Gastroenterology. 2010;138 (2):715-25. doi: 10.1053/j.gastro.2009.10.052. PubMed PMID:19900448 PubMed Central PMC2819588.

Search PubMed