Red-to-near-infrared fluorescence resonance energy transfer reporters for dual imaging applications
Tran VT-H, Ek F, Yassine H, Behera R, Hytönen V and Conway JRW (2026) Small Methods, e70828.
Publications
Key publications
Dynamic regulation of integrin beta1 phosphorylation supports invasive breast cancer progression
Conway JRW#, Joshi O, Kaivola J, Follain G, Gounis M, Kühl D and Ivaska J# (2025) Nature Cell Biology, DOI: 10.1038/s41556-025-01663-4 #Co-corresponding authors
Defined extracellular matrix compositions support stiffness-insensitive cell spreading and adhesion signaling
Conway JRW#, Isomursu A, Follain G, Härmä V, Jou-Ollé E, Pasquier N, Välimäki EPO, Rantala JK and Ivaska J# (2023) PNAS 120(43):e2304288120. #Co-corresponding authors
IGFBP2 secretion by mammary adipocytes limits breast cancer invasion
Conway JRW#, Dinç DD, Follain G, Paavolainen O, Kaivola J, Boström P, Hartiala P, Peuhu E and Ivaska J# (2023) Science Advances 9(28): eadg1840. #Co-corresponding authors
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse
Conway JRW, Warren SC, Lee Y-K, McCulloch AT, Magenau A, Lee V, Metcalf XL, Stoehr J, Haigh K, Abdulkhalek L, Guaman CS, Reed DA, Murphy KJ, Pereira BA, Mélénec P, Chambers C, Latham SL, Lenthall H, Deenick EK, Ma Y, Phan T, Lim E, Joshua AM, Walters S, Grey ST, Shi Y-C, Zhang L, Herzog H, Croucher DR, Philp A, Scheele CLGJ, Herrmann D, Sansom OJ, Morton JP, Papa A, Haigh JJ, Nobis M and Timpson P (2023) Science Advances 9(17): eadf9063.
Cell matrix adhesion in cell migration
Conway JRW and Jacquemet G (2019) Essays in Biochemistry. 63(5): 535-551.
Combating pancreatic cancer with PI3K pathway inhibitors in the era of personalised medicine
Conway JRW, Herrmann D, Evans TJ, Morton JP and Timpson P (2019) Gut. 68(4): 742-758.
Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer
Conway JRW, Warren SC, Herrmann D, Murphy KJ, Cazet AS, Vennin C, Shearer RF, Killen MJ, Magenau A, Mélénec P, Pinese M, Nobis M, Zaratzian A, Boulghourjian A, Da Silva AM, del Monte-Nieto G, Adam ASA, Harvey RP, Haigh JJ, Wang Y, Croucher DR, Sansom OJ, Pajic M, Caldon CE, Morton JP and Timpson P (2018) Cell reports. 23(11): 3312-3326.
Three-dimensional organotypic matrices from alternative collagen sources as pre-clinical models for cell biology
Conway JRW, Vennin C, Cazet AS, Herrmann D, Murphy KJ, Warren SC, Wullkopf L, Boulgourjian A, Zaratzian A, Da Silva AM, Pajic M, Morton JP, Cox TR and Timpson P (2017) Scientific Reports. 7(1): 16887.
Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors
Conway JRW, Warren SC and Timpson P (2017) Methods. 128:7 8-94.
Developments in preclinical cancer imaging: innovating the discovery of therapeutics
Conway JRW, Carragher NO and Timpson P (2014) Nature reviews. Cancer. 14(5): 314-328.