1. Translational Research
Evaluation of clinical patient charts, surgical techniques and data including histological evaluation of excised surgical tissue such as aortic tissue procured during resection of the dilated and dissecting aorta.
2. Clinical Research
Multicenter collaboration that consolidate the scientific cardiothoracic taskforce e.g. in the Nordic countries.
3. Experimental Research
Novel preclinical and surgical treatment concepts are investigated while using the rat heterotopic cardiac transplantation and volume-overload models. The objective is to study surgical means that may alleviate global, local and systematic inflammatory processes associated with ongoing ascending aortic dilatation and cardiac insufficiency.