Publication Hightlights

Dermal IgA Is Rare in Celiac Disease and Relatives and Lacks Dermatitis Herpetiformis-Type Colocalization with Transglutaminase 3

Turjanmaa E, Kaunisto H, Kemppainen E, Nilsson N, Hervonen K, Mankki I, Jernman J, Saavalainen P, Lempainen J, Alakoski A, De Leo L, Ziberna F, Reunala T, Kaukinen K, Lindfors K, Salmi T.

Full text of article Dermal IgA Is Rare in Celiac Disease and Relatives and Lacks Dermatitis Herpetiformis-Type Colocalization with Transglutaminase 3

Screening for Celiac Disease in Childhood: Cost-effectiveness of Multiple Genetic and Serological Testing Approaches

Mäkinen J, Heikkilä P, Pajula J, El Mekkaoui K, Størdal K, Lindfors K, Laiho JE, Ranta J, Rökman J, Hyöty H, Emmert-Streib F, Kurppa K, Kivelä L; HEDIMED Investigator Group

Full text of article Screening for Celiac Disease in Childhood: Cost-effectiveness of Multiple Genetic and Serological Testing Approaches

Low positive and borderline negative transglutaminase antibody levels are frequently associated with a coeliac disease diagnosis

Nurmi R, Turunen Beteta C, Kurppa K, Huhtala H, Lindfors K, Kivelä L, Kaukinen K, Paavola S.

Full text of article Low positive and borderline negative transglutaminase antibody levels are frequently associated with a coeliac disease diagnosis

Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease

Dotsenko V, Tewes B, Hils M, Pasternack R, Isola J, Taavela J, Popp A, Sarin J, Huhtala H, Hiltunen P, Zimmermann T, Mohrbacher R, Greinwald R, Lundin KEA, Schuppan D, Mäki M, Viiri K; CEC-3 Investigators.

Full text of article Transcriptomic analysis of intestine following administration of a transglutaminase 2 inhibitor to prevent gluten-induced intestinal damage in celiac disease

Trends in the prevalence rates and predictive factors of coeliac disease: A long-term nationwide follow-up study

Taavela J, Kurppa K, Jääskeläinen T, Kaartinen NE, Rissanen H, Huhtala H, Mäki M, Kaukinen K.

Full text of article Trends in the prevalence rates and predictive factors of coeliac disease: A long-term nationwide follow-up study

Celiac Disease Affects 1% of Global Population: Who Will Manage All These Patients?

Kurppa K, Mulder CJ, Stordal K, Kaukinen K.

Full text of article Celiac Disease Affects 1% of Global Population: Who Will Manage All These Patients?

Hippocampal sclerosis is associated with celiac disease type immunity in patients with drug-resistant temporal lobe epilepsy

Peltola M, Kaukinen K, Basnyat P, Raitanen J, Haimila K, Liimatainen S, Rainesalo S, Peltola J.

Full text of article Hippocampal sclerosis is associated with celiac disease type immunity in patients with drug-resistant temporal lobe epilepsy

Risk of vascular diseases in patients with dermatitis herpetiformis and coeliac disease: a long-term cohort study

Nilsson N, Leivo J, Collin P, Koskinen I, Kaukinen K, Huhtala H, Palmio J, Reunala T, Hervonen K, Salmi T, Pasternack C.

Full text of article Risk of vascular diseases in patients with dermatitis herpetiformis and coeliac disease: a long-term cohort study

The risk of renal comorbidities in celiac disease patients depends on the phenotype of celiac disease

Nurmi R, Pasternack C, Salmi T, Hervonen K, Koskinen I, Järvelin J, Huhtala H, Collin P, Mustonen J, Kaukinen K, Mäkelä S.

Full text of article The risk of renal comorbidities in celiac disease patients depends on the phenotype of celiac disease

Significance of low ferritin without anaemia in screen-detected, adult coeliac disease patients

Repo M, Kurppa K, Huhtala H, Luostarinen L, Kaukinen K, Kivelä L.

Full text of article Significance of low ferritin without anaemia in screen-detected, adult coeliac disease patients

Nomenclature and diagnosis of seronegative coeliac disease and chronic non-coeliac enteropathies in adults: the Paris consensus

Schiepatti A, Sanders DS, Baiardi P, Caio G, Ciacci C, Kaukinen K, Lebwohl B, Leffler D, Malamut G, Murray JA, Rostami K, Rubio-Tapia A, Volta U, Biagi F.

Full text of article Nomenclature and diagnosis of seronegative coeliac disease and chronic non-coeliac enteropathies in adults: the Paris consensus

A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease

Schuppan D*, Mäki M*, Lundin KEA, Isola J, Friesing-Sosnik T, Taavela J, Popp A, Koskenpato J, Langhorst J, Hovde Ø, Lähdeaho ML, Fusco S, Schumann M, Török HP, Kupcinskas J, Zopf Y, Lohse AW, Scheinin M, Kull K, Biedermann L, Byrnes V, Stallmach A, Jahnsen J, Zeitz J, Mohrbacher R, Greinwald R; CEC-3 Trial Group

Full text of article A Randomized Trial of a Transglutaminase 2 Inhibitor for Celiac Disease

Current and emerging therapies for coeliac disease

Kivelä L, Caminero A, Leffler DA, Pinto-Sanchez MI, Tye-Din JA, Lindfors K.

Full text of article Current and emerging therapies for coeliac disease

Presence of high-risk HLA genotype is the most important individual risk factor for coeliac disease among at-risk relatives

Paavola S, Lindfors K, Kivelä L, Cerqueira J, Huhtala H, Saavalainen P, Tauschi R, Kaukinen K, Kurppa K.

Full text of article Presence of high-risk HLA genotype is the most important individual risk factor for coeliac disease among at-risk relatives

Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes

Cerqueira JXM, Saavalainen P, Kurppa K, Laurikka P, Huhtala H, Nykter M, L E Koskinen L, Yohannes DA, Kilpeläinen E, Shcherban A, Palotie A, Kaukinen K, Lindfors K.

Full text of article Independent and cumulative coeliac disease-susceptibility loci are associated with distinct disease phenotypes

Genome-Wide Transcriptomic Analysis of Intestinal Mucosa in Celiac Disease Patients on a Gluten-Free Diet and Postgluten Challenge

Dotsenko V, Oittinen M, Taavela J, Popp A, Peräaho M, Staff S, Sarin J, Leon F, Isola J, Mäki M, Viiri K.

Full text of article Genome-Wide Transcriptomic Analysis of Intestinal Mucosa in Celiac Disease Patients on a Gluten-Free Diet and Postgluten Challenge

Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study

Lindfors K, Lin J, Lee HS, Hyöty H, Nykter M, Kurppa K, Liu E, Koletzko S, Rewers M, Hagopian W, Toppari J, Ziegler AG, Akolkar B, Krischer JP, Petrosino JF, Lloyd RE, Agardh D; TEDDY Study Group

Full text of article Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study

Gliadin-Induced Ex Vivo T-Cell Response in Dermatitis Herpetiformis: A Predictor of Clinical Relapse on Gluten Challenge?

Kalliokoski S, Mansikka E, de Kauwe A, Huhtala H, Saavalainen P, Kurppa K, Hervonen K, Reunala T, Kaukinen K, Salmi T, Lindfors K.

Full text of article Gliadin-Induced Ex Vivo T-Cell Response in Dermatitis Herpetiformis: A Predictor of Clinical Relapse on Gluten Challenge?

X-ray microtomography is a novel method for accurate evaluation of small-bowel mucosal morphology and surface area

Virta J, Hannula M, Tamminen I, Lindfors K, Kaukinen K, Popp A, Taavela J, Saavalainen P, Hiltunen P, Hyttinen J, Kurppa K.

Full text of article X-ray microtomography is a novel method for accurate evaluation of small-bowel mucosal morphology and surface area

European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020

Husby S, Koletzko S, Korponay-Szabó I, Kurppa K, Mearin ML, Ribes-Koninckx C, Shamir R, Troncone R, Auricchio R, Castillejo G, Christensen R, Dolinsek J, Gillett P, Hróbjartsson A, Koltai T, Maki M, Nielsen SM, Popp A, Størdal K, Werkstetter K, Wessels M.

Full text of article European Society Paediatric Gastroenterology, Hepatology and Nutrition Guidelines for Diagnosing Coeliac Disease 2020

Overall and Cause-Specific Mortality in Adult Celiac Disease and Dermatitis Herpetiformis Diagnosed in the 21st Century

Koskinen I, Virta LJ, Huhtala H, Ilus T, Kaukinen K, Collin P.

Full text of article Overall and Cause-Specific Mortality in Adult Celiac Disease and Dermatitis Herpetiformis Diagnosed in the 21st Century

Coeliac disease

Lindfors K, Ciacci C, Kurppa K, Lundin KEA, Makharia GK, Mearin ML, Murray JA, Verdu EF, Kaukinen K.

Full text of article Coeliac disease

Serology-based criteria for adult coeliac disease have excellent accuracy across the range of pre-test probabilities

Fuchs V, Kurppa K, Huhtala H, Laurila K, Mäki M, Collin P, Salmi T, Luostarinen L, Saavalainen P, Kaukinen K.

Full text of article Serology-based criteria for adult coeliac disease have excellent accuracy across the range of pre-test probabilities

Gluten Challenge Induces Skin and Small Bowel Relapse in Long-Term Gluten-Free Diet-Treated Dermatitis Herpetiformis

Mansikka E, Hervonen K, Kaukinen K, Ilus T, Oksanen P, Lindfors K, Laurila K, Hietikko M, Taavela J, Jernman J, Saavalainen P, Reunala T, Salmi T.

Full text of article Gluten Challenge Induces Skin and Small Bowel Relapse in Long-Term Gluten-Free Diet-Treated Dermatitis Herpetiformis