Researchers of the Computational Biophysics & Imaging Group and the Heart group joined forces and wrote a review addressing arrhythmia mechanisms in human induced pluripotent stem cell–derived cardiomyocytes. The authors review the advances that the human induced pluripotent stem cell–based modeling systems have brought so far regarding the understanding of both arrhythmogenic triggers and substrates, while also briefly speculating the possibilities in the future.
This review article is again a nice example of the great multidisciplinary collaboration of CoEBoC.
Paci Michelangelo, Penttinen Kirsi, Pekkanen-Mattila Mari, Koivumäki Jussi T.
Journal of Cardiovascular Pharmacology: March 2021 – Volume 77 – Issue 3 – p 300-316
doi: 10.1097/FJC.0000000000000972