Comparative microelectrode array data of the functional development of hPSC-derived and rat neuronal networks
Fikret Emre Kapucu, Andrey Vinogradov, Tanja Hyvärinen, Laura Ylä-Outinen & Susanna Narkilahti
Publications
Publications 2022
Human Neurons Form Axon-Mediated Functional Connections with Human Cardiomyocytes in Compartmentalized Microfluidic Chip
Martta Häkli,Satu Jäntti,Tiina Joki,Lassi Sukki,Kaisa Tornberg, Katriina Aalto-Setälä, Pasi Kallio, Mari Pekkanen-Mattila and Susanna Narkilahti
Cardiac Ischemia On-a-Chip: Antiarrhythmic Effect of Levosimendan on Ischemic Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
Gaballah, M, Penttinen, K, Kreutzer, J, Mäki, AJ, Kallio, P, Aalto-Setälä, K
A kainic acid-induced seizure model in human pluripotent stem cell-derived cortical neurons for studying the role of IL-6 in the functional activity
Ropafadzo Mzezewa, Johanna Lotila, Heikki Kiiski, Andrey Vinogradov, Fikret Emre Kapucu, Jukka Peltola, Sanna Hagman, Susanna Narkilahti
Vasculogenic Potency of Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stem/Stromal Cells Results in Differing Vascular Network Phenotypes in a Microfluidic Chip
Anastasiia Mykuliak, Alma Yrjänäinen, Antti-Juhana Mäki, Gebraad, Lampela, Kääriäinen, Toni-Karri Pakarinen, Pasi Kallio, Susanna Miettinen, Hanna Vuorenpää
Self-assembled cellulose nanofiber–carbon nanotube nanocomposite films with anisotropic conductivity
Anne Skogberg, Sanna Siljander, Antti-Juhana Mäki, Mari Honkanen, Alexander Efimov, Markus Hannula, Panu Lahtinen, Sampo Tuukkanen, Tomas Björkqvist and Pasi Kallio
Microfabricated porous SU-8 membranes as innervation interfaces for hiPSC-neurons in microfluidic devices
T Salpavaara, T Joki, A Skogberg, M T Calejo, J Lekkala, S Narkilahti and P Kallio
Data analytics for cardiac diseases
Martti Juhola, Henry Joutsijoki, Kirsi Penttinen, Disheet Shah, Risto-Pekka Pölönen, Katriina Aalto-Setälä
Two-step crosslinking to enhance the printability of methacrylated gellan gum biomaterial ink for extrusion-based 3D bioprinting
Hatai Jongprasitkul, Sanna Turunen, Vijay Singh, Parihar, Minna Kellomäki
Publications 2021
Human induced pluripotent stem cell-based platform for modeling cardiac ischemia
Martta Häkli, Joose Kreutzer, Antti-Juhana Mäki, Hannu Välimäki, Henna Lappi, Heini Huhtala, Pasi Kallio, Katriina Aalto-Setälä & Mari Pekkanen-Mattila
Bidirectional cell-matrix interaction dictates neuronal network formation in a brain-mimetic 3D scaffold
Sumanta Samanta, Laura Ylä-Outinen, Vignesh Kumar, Rangasami, Susanna Narkilahti, Oommen P.Oommen
A mathematical model of hiPSC cardiomyocytes electromechanics
Mohamadamin Forouzandehmehr, Jussi T. Koivumäki, Jari Hyttinen, Michelangelo Paci
Astrocytes Exhibit a Protective Role in Neuronal Firing Patterns under Chemically Induced Seizures in Neuron–Astrocyte Co-Cultures
Annika Ahtiainen, Barbara Genocchi, Jarno M. A. Tanskanen, Michael T. Barros, Jari A. K. Hyttinen and Kerstin Lenk
Sensitivity of the Human Ventricular BPS2020 Action Potential Model to the In Silico Mechanisms of Ischemia
Mohamadamin Forouzandehmehr, Chiara Bartolucci, Jari Hyttinen, Jussi T Koivumäki, Michelangelo Paci
Multifrequency electrical impedance tomography in biological applications: A multimodal perspective
Mari Lehti-Polojärvi, Olli Koskela, Jari Hyttinen
Optical Projection Tomography for Particle Counting and Morphology Analysis
Olli Koskela, Md Tanvirul Kabir Chowdhury, Toni Montonen, Birhanu Belay, Sampsa Pursiainen, Jari Hyttinen
Analysis of Drug Effects on iPSC Cardiomyocytes with Machine Learning
Martti Juhola, Kirsi Penttinen, Henry Joutsijoki, Katriina Aalto-Setälä
On computational classification of genetic cardiac diseases applying iPSC cardiomyocytes
Martti Juhola, Henry Joutsijoki, Kirsi Penttinen, Disheet Shah, Katriina Aalto-Setälä
Electrophysiological evaluation of human induced pluripotent stem cell-derived cardiomyocytes obtained by different methods
Chandra Prajapati, Marisa Ojala, Henna Lappi, Katriina Aalto-Setälä, Mari Pekkanen-Mattila
Retrieval of the conductivity spectrum of tissues in vitro with novel multimodal tomography
M Lehti-Polojärvi, M J Räsänen, L E Viiri, H Vuorenpää, S Miettinen, A Seppänen and J Hyttinen
Evaluation of the effect of donor weight on adipose stromal/stem cell characteristics by using weight-discordant monozygotic twin pairs
Miia Juntunen, Sini Heinonen, Heini Huhtala, Aila Rissanen, Jaakko Kaprio, Kirsi Kuismanen, Kirsi H. Pietiläinen, Susanna Miettinen & Mimmi Patrikoski
Chemical modification strategies for viscosity-dependent processing of gellan gum
Christine Gering, Anum Rasheed, Janne T. Koivisto, Jenny Párraga, Sampo Tuukkanen, Minna Kellomäki
Comprehensive characterisation of the compressive behaviour of hydrogels using a new modelling procedure and redefining compression testing
Jairan Nafar Dastgerdi, Janne T.Koivisto, Olli Orell, Pantea Rava, Jarno Jokinenen, Mikko Kanerva, Minna Kellomäki
Directional Growth of Human Neuronal Axons in a Microfluidic Device with Nanotopography on Azobenzene-Based Material
Mervi Ristola, Chiara Fedele, Sanna Hagman, Lassi Sukki, Fikret Emre Kapucu, Ropafadzo Mzezeva, Tanja Hyvärinen, Pasi Kallio, Arri Priimagi, Susanna Narkilahti.
Optical projection tomography as a quantitative tool for analysis of cell morphology and density in 3D hydrogels
Birhanu Belay, Janne T Koivisto, Jenny Parraga, Olli Koskela, Toni Montonen, Minna Kellomäki, Edite Figueiras, Jari Hyttinen.
Paci Michelangelo, Penttinen Kirsi, Pekkanen-Mattila Mari, Koivumäki Jussi T.
Paci Michelangelo, Penttinen Kirsi, Pekkanen-Mattila Mari, Koivumäki Jussi T.
Photocross-linkable Methacrylated Polypeptides and Polysaccharides for Casting, Injecting, and 3D Fabrication.
Hatai Jongprasitkul, Sanna Turunen, Vijay Singh Parihar, Shambhavee Annurakshita, and Minna Kellomäki
Stem cell-based platform for modeling cardiac ischemia
Martta Häkli, Joose Kreutzer, Antti-Juhana Mäki, Hannu Välimäki, Henna Lappi, Heini Huhtala, Pasi Kallio, Katriina Aalto-Setälä & Mari Pekkanen-Mattila
Electrophysiological evaluation of human induced pluripotent stem cell-derived cardiomyocytes obtained by different methods
Chandra Prajapati , Marisa Ojala, Henna Lappi, Katriina Aalto-Setälä, Mari Pekkanen-Mattila
Publications 2020
hiPSC-Derived Cardiomyocyte Model of LQT2 Syndrome Derived from Asymptomatic and Symptomatic Mutation Carriers Reproduces Clinical Differences in Aggregates but Not in Single Cells.
Shah D, Prajapati C, Penttinen K, Cherian RM, Koivumäki JT, Alexanova A, Hyttinen J, Aalto-Setälä K
Covalent immobilization of luminescent oxygen indicators reduces cytotoxicity
Välimäki H, Hyvärinen T, Leivo J, Iftikhar H, Pekkanen-Mattila M, Rajan DK, Verho J, Kreutzer J, Ryynänen T, Pirhonen J, Aalto-Setälä K, Kallio P, Narkilahti S, Lekkala J.
Bioactive glass ions for in vitro osteogenesis and microvascularization in gellan gum-collagen hydrogels.
Vuornos K, Huhtala H, Kääriäinen M, Kuismanen K, Hupa L, Kellomäki M, Miettinen S
Pneumatic unidirectional cell stretching device for mechanobiological studies of cardiomyocytes.
Kreutzer J, Viehrig M, Pölönen RP, Zhao F, Ojala M, Aalto-Setälä K, Kallio P.
Transparent Microelectrode Arrays Fabricated by Ion Beam Assisted Deposition for Neuronal Cell in Vitro Recordings
Ryynänen T, Mzezewa R, Meriläinen E, Hyvärinen T, Lekkala J, Narkilahti S, Kallio P.