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Decision Support for Health (DSH)

Publications (Hannu Nieminen)

Our current research focus is on utilizing the tools and methods of data science for analyzing and visualizing the health and wellness status and its predicted evolution.

Major Publications

Helander E, Wansink B, Chieh A. Weight Gain over the Holidays in Three Countries. N Engl J Med 2016; 375:1200-1202.

Föhr T, Pietilä J, Helander E, Myllymäki T, Lindholm H, Rusko H, Kujala UM. Physical activity, body mass index and heart rate variability-based stress and recovery in 16 275 Finnish employees: a cross-sectional study. BMC Public Health. 2016 Aug 2;16:701.

Helander E, Kaipainen K, Korhonen I, Wansink B. Factors related to sustained use of a free mobile app for dietary self-monitoring with photography and peer feedback: retrospective cohort study. J Med Internet Res 2014;16(4)/ e109: 1-13.

Honko H, Andalibi V, Aaltonen T, Parak J, Saaranen M, Viik J, Korhonen I. W2E – Wellness Warehouse Engine for Semantic Interoperability of Consumer Health Data. IEEE J Biomed Health Inform. 2015 Aug 18.

Ledesma A, Al-Musawi M, and Nieminen H. Health Figures: an open source JavaScript library for health data visualization. BMC Medical Informatics and Decision Making Journal. DOI: 10.1186/s12911-016-0275-6. 22 March, 2016.

2021

  1. Johansson, K, Mustonen, H, Nieminen, H, Haglund, C, Lehtimäki, TE, Seppänen, H et al.. MRI follow-up for pancreatic intraductal papillary mucinous neoplasm: an ultrashort versus long protocol. Abdom Radiol (NY). 2022;47 (2):727-737. doi: 10.1007/s00261-021-03382-4. PubMed PMID:34923598 PubMed Central PMC8807431.
  2. Potts, C, Ennis, E, Bond, RB, Mulvenna, MD, McTear, MF, Boyd, K et al.. Chatbots to Support Mental Wellbeing of People Living in Rural Areas: Can User Groups Contribute to Co-design?. J Technol Behav Sci. 2021;6 (4):652-665. doi: 10.1007/s41347-021-00222-6. PubMed PMID:34568548 PubMed Central PMC8450556.
  3. Redekop, EA, Johansson, N, Kokkonen, E, Urpelainen, S, Lopes da Silva, F, Kaipio, M et al.. Synchronizing gas injections and time-resolved data acquisition for perturbation-enhanced APXPS experiments. Rev Sci Instrum. 2021;92 (4):044101. doi: 10.1063/5.0039957. PubMed PMID:34243480 .
  4. Perra, E, Lampsijärvi, E, Barreto, G, Arif, M, Puranen, T, Hæggström, E et al.. Ultrasonic actuation of a fine-needle improves biopsy yield. Sci Rep. 2021;11 (1):8234. doi: 10.1038/s41598-021-87303-x. PubMed PMID:33859220 PubMed Central PMC8050323.
  5. Sørup, S, Englund, H, Laake, I, Nieminen, H, Gehrt, L, Feiring, B et al.. Revaccination with measles-mumps-rubella vaccine and hospitalization for infection in Denmark and Sweden – An interrupted time-series analysis. Vaccine. 2022;40 (11):1583-1593. doi: 10.1016/j.vaccine.2021.01.028. PubMed PMID:33518465 .

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2020

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2019

  1. Pakarinen, T, Pietila, J, Nieminen, H. Prediction of Self-Perceived Stress and Arousal Based on Electrodermal Activity. Annu Int Conf IEEE Eng Med Biol Soc. 2019;2019 :2191-2195. doi: 10.1109/EMBC.2019.8857621. PubMed PMID:31946336 .
  2. Nieminen, HJ, Lampsijärvi, E, Barreto, G, Finnilä, MAJ, Salmi, A, Airaksinen, AJ et al.. Localized delivery of compounds into articular cartilage by using high-intensity focused ultrasound. Sci Rep. 2019;9 (1):15937. doi: 10.1038/s41598-019-52012-z. PubMed PMID:31685841 PubMed Central PMC6828772.
  3. Karhula, SS, Finnilä, MAJ, Rytky, SJO, Cooper, DM, Thevenot, J, Valkealahti, M et al.. Quantifying Subresolution 3D Morphology of Bone with Clinical Computed Tomography. Ann Biomed Eng. 2020;48 (2):595-605. doi: 10.1007/s10439-019-02374-2. PubMed PMID:31583552 PubMed Central PMC6949315.
  4. Hakkarainen, E, Kõrkjas, A, Laidmäe, I, Lust, A, Semjonov, K, Kogermann, K et al.. Comparison of Traditional and Ultrasound-Enhanced Electrospinning in Fabricating Nanofibrous Drug Delivery Systems. Pharmaceutics. 2019;11 (10):. doi: 10.3390/pharmaceutics11100495. PubMed PMID:31561640 PubMed Central PMC6835569.
  5. Iivonen, T, Heikkilä, MJ, Popov, G, Nieminen, HE, Kaipio, M, Kemell, M et al.. Atomic Layer Deposition of Photoconductive CuO Thin Films. ACS Omega. 2019;4 (6):11205-11214. doi: 10.1021/acsomega.9b01351. PubMed PMID:31460221 PubMed Central PMC6648912.
  6. Ledesma, A, Bidargaddi, N, Strobel, J, Schrader, G, Nieminen, H, Korhonen, I et al.. Health timeline: an insight-based study of a timeline visualization of clinical data. BMC Med Inform Decis Mak. 2019;19 (1):170. doi: 10.1186/s12911-019-0885-x. PubMed PMID:31438942 PubMed Central PMC6704521.
  7. Värri, A, Kranz-Zuppan, P, de la Cruz, R. IEC 62304 Ed. 2: Software Life Cycle Standard for Health Software. Stud Health Technol Inform. 2019;264 :868-872. doi: 10.3233/SHTI190347. PubMed PMID:31438048 .
  8. Nieminen, H, Rinta-Kokko, H, Jokinen, J, Puumalainen, T, Moreira, M, Borys, D et al.. Effectiveness of the 10-valent pneumococcal conjugate vaccine among girls, boys, preterm and low-birth-weight infants – Results from a randomized, double-blind vaccine trial. Vaccine. 2019;37 (28):3715-3721. doi: 10.1016/j.vaccine.2019.05.033. PubMed PMID:31122856 .
  9. Pritzker, KPH, Nieminen, HJ. Needle Biopsy Adequacy in the Era of Precision Medicine and Value-Based Health Care. Arch Pathol Lab Med. 2019;143 (11):1399-1415. doi: 10.5858/arpa.2018-0463-RA. PubMed PMID:31100015 .
  10. Jauhiainen, M, Puustinen, J, Mehrang, S, Ruokolainen, J, Holm, A, Vehkaoja, A et al.. Identification of Motor Symptoms Related to Parkinson Disease Using Motion-Tracking Sensors at Home (KÄVELI): Protocol for an Observational Case-Control Study. JMIR Res Protoc. 2019;8 (3):e12808. doi: 10.2196/12808. PubMed PMID:30916665 PubMed Central PMC6456828.
  11. Veira Canle, D, Kekkonen, T, Mäkinen, J, Puranen, T, Nieminen, HJ, Kuronen, A et al.. Practical realization of a sub-λ/2 acoustic jet. Sci Rep. 2019;9 (1):5189. doi: 10.1038/s41598-019-41335-6. PubMed PMID:30914658 PubMed Central PMC6435727.
  12. Ylitalo, T, Finnilä, MAJ, Gahunia, HK, Karhula, SS, Suhonen, H, Valkealahti, M et al.. Quantifying Complex Micro-Topography of Degenerated Articular Cartilage Surface by Contrast-Enhanced Micro-Computed Tomography and Parametric Analyses. J Orthop Res. 2019;37 (4):855-866. doi: 10.1002/jor.24245. PubMed PMID:30737811 PubMed Central PMC6518937.
  13. Kauppinen, S, Karhula, SS, Thevenot, J, Ylitalo, T, Rieppo, L, Kestilä, I et al.. 3D morphometric analysis of calcified cartilage properties using micro-computed tomography. Osteoarthritis Cartilage. 2019;27 (1):172-180. doi: 10.1016/j.joca.2018.09.009. PubMed PMID:30287395 .

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2018

  1. Mehrang, S, Jauhiainen, M, Pietil, J, Puustinen, J, Ruokolainen, J, Nieminen, H et al.. Identification of Parkinson’s Disease Utilizing a Single Self-recorded 20-step Walking Test Acquired by Smartphone’s Inertial Measurement Unit. Annu Int Conf IEEE Eng Med Biol Soc. 2018;2018 :2913-2916. doi: 10.1109/EMBC.2018.8512921. PubMed PMID:30441010 .
  2. Kauppinen, S, Karhula, SS, Thevenot, J, Ylitalo, T, Rieppo, L, Kestilä, I et al.. 3D morphometric analysis of calcified cartilage properties using micro-computed tomography. Osteoarthritis Cartilage. 2019;27 (1):172-180. doi: 10.1016/j.joca.2018.09.009. PubMed PMID:30287395 .
  3. Kilpi, TM, Jokinen, J, Puumalainen, T, Nieminen, H, Ruokokoski, E, Rinta-Kokko, H et al.. Effectiveness of pneumococcal Haemophilus influenzae protein D conjugate vaccine against pneumonia in children: A cluster-randomised trial. Vaccine. 2018;36 (39):5891-5901. doi: 10.1016/j.vaccine.2018.08.020. PubMed PMID:30145098 .
  4. Kestilä, I, Thevenot, J, Finnilä, MA, Karhula, SS, Hadjab, I, Kauppinen, S et al.. In vitro method for 3D morphometry of human articular cartilage chondrons based on micro-computed tomography. Osteoarthritis Cartilage. 2018;26 (8):1118-1126. doi: 10.1016/j.joca.2018.05.012. PubMed PMID:29802974 PubMed Central PMC6058088.
  5. Nieminen, HJ, Laidmäe, I, Salmi, A, Rauhala, T, Paulin, T, Heinämäki, J et al.. Ultrasound-enhanced electrospinning. Sci Rep. 2018;8 (1):4437. doi: 10.1038/s41598-018-22124-z. PubMed PMID:29535342 PubMed Central PMC5849615.
  6. Palmu, AA, Jokinen, J, Nieminen, H, Rinta-Kokko, H, Ruokokoski, E, Puumalainen, T et al.. Vaccine-preventable disease incidence of pneumococcal conjugate vaccine in the Finnish invasive pneumococcal disease vaccine trial. Vaccine. 2018;36 (14):1816-1822. doi: 10.1016/j.vaccine.2018.02.088. PubMed PMID:29503110 .
  7. Perez-Macias, JM, Tenhunen, M, Varri, A, Himanen, SL, Viik, J, Perez-Macias, JM et al.. Detection of Snores Using Source Separation on an Emfit Signal. IEEE J Biomed Health Inform. 2018;22 (4):1157-1167. doi: 10.1109/JBHI.2017.2757530. PubMed PMID:28961132 .

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2017

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2016

  1. Perez-Macias, JM, Viik, J, Varri, A, Himanen, SL, Tenhunen, M. Spectral analysis of snoring events from an Emfit mattress. Physiol Meas. 2016;37 (12):2130-2143. doi: 10.1088/0967-3334/37/12/2130. PubMed PMID:27811388 .
  2. Raissadati, A, Nieminen, H, Haukka, J, Sairanen, H, Jokinen, E. Late Causes of Death After Pediatric Cardiac Surgery: A 60-Year Population-Based Study. J Am Coll Cardiol. 2016;68 (5):487-498. doi: 10.1016/j.jacc.2016.05.038. PubMed PMID:27470457 .
  3. Ledesma, A, Al-Musawi, M, Nieminen, H. Health figures: an open source JavaScript library for health data visualization. BMC Med Inform Decis Mak. 2016;16 :38. doi: 10.1186/s12911-016-0275-6. PubMed PMID:27000796 PubMed Central PMC4802654.

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2015

  1. Ledesma, A, Nieminen, H, Valve, P, Ermes, M, Jimison, H, Pavel, M et al.. The shape of health: A comparison of five alternative ways of visualizing personal health and wellbeing. Annu Int Conf IEEE Eng Med Biol Soc. 2015;2015 :7638-41. doi: 10.1109/EMBC.2015.7320161. PubMed PMID:26738061 .
  2. Sundvik, M, Nieminen, HJ, Salmi, A, Panula, P, Hæggström, E. Effects of acoustic levitation on the development of zebrafish, Danio rerio, embryos. Sci Rep. 2015;5 :13596. doi: 10.1038/srep13596. PubMed PMID:26337364 PubMed Central PMC4559763.
  3. Palmu, AA, Jokinen, J, Nieminen, H, Rinta-Kokko, H, Ruokokoski, E, Puumalainen, T et al.. Effectiveness of the Ten-valent Pneumococcal Conjugate Vaccine Against Tympanostomy Tube Placements in a Cluster-randomized Trial. Pediatr Infect Dis J. 2015;34 (11):1230-5. doi: 10.1097/INF.0000000000000857. PubMed PMID:26284652 .
  4. Nieminen, H, Syrjänen, RK, Puumalainen, T, Sirén, P, Palmu, AA. Health benefit for the child and promotion of the common good were the two most important reasons for participation in the FinIP vaccine trial. Vaccine. 2015;33 (31):3695-702. doi: 10.1016/j.vaccine.2015.06.010. PubMed PMID:26073011 .
  5. Nieminen, HJ, Ylitalo, T, Karhula, S, Suuronen, JP, Kauppinen, S, Serimaa, R et al.. Determining collagen distribution in articular cartilage using contrast-enhanced micro-computed tomography. Osteoarthritis Cartilage. 2015;23 (9):1613-21. doi: 10.1016/j.joca.2015.05.004. PubMed PMID:26003951 PubMed Central PMC4565718.
  6. Nieminen, HJ, Ylitalo, T, Suuronen, JP, Rahunen, K, Salmi, A, Saarakkala, S et al.. Delivering Agents Locally into Articular Cartilage by Intense MHz Ultrasound. Ultrasound Med Biol. 2015;41 (8):2259-65. doi: 10.1016/j.ultrasmedbio.2015.03.025. PubMed PMID:25922135 PubMed Central PMC4587538.
  7. Raissadati, A, Nieminen, H, Jokinen, E, Sairanen, H. Progress in late results among pediatric cardiac surgery patients: a population-based 6-decade study with 98% follow-up. Circulation. 2015;131 (4):347-53; discussion 353. doi: 10.1161/CIRCULATIONAHA.114.011190. PubMed PMID:25538229 .
  8. Ylitalo, P, Nieminen, H, Pitkänen, OM, Jokinen, E, Sairanen, H. Need of transannular patch in tetralogy of Fallot surgery carries a higher risk of reoperation but has no impact on late survival: results of Fallot repair in Finland. Eur J Cardiothorac Surg. 2015;48 (1):91-7. doi: 10.1093/ejcts/ezu401. PubMed PMID:25326015 .

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