Skip to content
Prostate Cancer Research Center

Faculty of Medicine and Health Technology

Bioimage informatics

2020

  1. Mehtonen, J, Teppo, S, Lahnalampi, M, Kokko, A, Kaukonen, R, Oksa, L et al.. Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable transcription factor activities. Genome Med. 2020;12 (1):99. doi: 10.1186/s13073-020-00799-2. PubMed PMID:33218352 PubMed Central PMC7679990.
  2. Borovec, J, Kybic, J, Arganda-Carreras, I, Sorokin, DV, Bueno, G, Khvostikov, AV et al.. ANHIR: Automatic Non-Rigid Histological Image Registration Challenge. IEEE Trans Med Imaging. 2020;39 (10):3042-3052. doi: 10.1109/TMI.2020.2986331. PubMed PMID:32275587 PubMed Central PMC7584382.
  3. Doan, P, Musa, A, Murugesan, A, Sipilä, V, Candeias, NR, Emmert-Streib, F et al.. Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways. Cells. 2020;9 (3):. doi: 10.3390/cells9030681. PubMed PMID:32164385 PubMed Central PMC7140667.
  4. Ström, P, Kartasalo, K, Olsson, H, Solorzano, L, Delahunt, B, Berney, DM et al.. Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study. Lancet Oncol. 2020;21 (2):222-232. doi: 10.1016/S1470-2045(19)30738-7. PubMed PMID:31926806 .
  5. Valkonen, M, Isola, J, Ylinen, O, Muhonen, V, Saxlin, A, Tolonen, T et al.. Cytokeratin-Supervised Deep Learning for Automatic Recognition of Epithelial Cells in Breast Cancers Stained for ER, PR, and Ki-67. IEEE Trans Med Imaging. 2020;39 (2):534-542. doi: 10.1109/TMI.2019.2933656. PubMed PMID:31398111 .

Search PubMed

2019

  1. Liimatainen, K, Latonen, L, Kartasalo, K, Ruusuvuori, P. 3D-Printed Whole Prostate Models with Tumor Hotspots Using Dual-Extruder Printer. Annu Int Conf IEEE Eng Med Biol Soc. 2019;2019 :2867-2871. doi: 10.1109/EMBC.2019.8857068. PubMed PMID:31946490 .
  2. Eerola, SK, Santio, NM, Rinne, S, Kouvonen, P, Corthals, GL, Scaravilli, M et al.. Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion. Cell Commun Signal. 2019;17 (1):148. doi: 10.1186/s12964-019-0463-y. PubMed PMID:31730483 PubMed Central PMC6858710.
  3. Valkonen, M, Isola, J, Ylinen, O, Muhonen, V, Saxlin, A, Tolonen, T et al.. Cytokeratin-Supervised Deep Learning for Automatic Recognition of Epithelial Cells in Breast Cancers Stained for ER, PR, and Ki-67. IEEE Trans Med Imaging. 2020;39 (2):534-542. doi: 10.1109/TMI.2019.2933656. PubMed PMID:31398111 .
  4. Liimatainen, K, Kananen, L, Latonen, L, Ruusuvuori, P. Iterative unsupervised domain adaptation for generalized cell detection from brightfield z-stacks. BMC Bioinformatics. 2019;20 (1):80. doi: 10.1186/s12859-019-2605-z. PubMed PMID:30767778 PubMed Central PMC6376647.

Search PubMed

2018

Search PubMed

2017

  1. Ehteshami Bejnordi, B, Veta, M, Johannes van Diest, P, van Ginneken, B, Karssemeijer, N, Litjens, G et al.. Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer. JAMA. 2017;318 (22):2199-2210. doi: 10.1001/jama.2017.14585. PubMed PMID:29234806 PubMed Central PMC5820737.
  2. Latonen, L, Scaravilli, M, Gillen, A, Hartikainen, S, Zhang, FP, Ruusuvuori, P et al.. In Vivo Expression of miR-32 Induces Proliferation in Prostate Epithelium. Am J Pathol. 2017;187 (11):2546-2557. doi: 10.1016/j.ajpath.2017.07.012. PubMed PMID:28827140 .
  3. Valkonen, M, Kartasalo, K, Liimatainen, K, Nykter, M, Latonen, L, Ruusuvuori, P et al.. Metastasis detection from whole slide images using local features and random forests. Cytometry A. 2017;91 (6):555-565. doi: 10.1002/cyto.a.23089. PubMed PMID:28426134 .
  4. Granberg, KJ, Annala, M, Lehtinen, B, Kesseli, J, Haapasalo, J, Ruusuvuori, P et al.. Strong FGFR3 staining is a marker for FGFR3 fusions in diffuse gliomas. Neuro Oncol. 2017;19 (9):1206-1216. doi: 10.1093/neuonc/nox028. PubMed PMID:28379477 PubMed Central PMC5570261.
  5. Valkonen, M, Ruusuvuori, P, Kartasalo, K, Nykter, M, Visakorpi, T, Latonen, L et al.. Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models. Sci Rep. 2017;7 :44831. doi: 10.1038/srep44831. PubMed PMID:28317907 PubMed Central PMC5357939.
  6. Huttunen, M, Turkki, P, Mäki, A, Paavolainen, L, Ruusuvuori, P, Marjomäki, V et al.. Echovirus 1 internalization negatively regulates epidermal growth factor receptor downregulation. Cell Microbiol. 2017;19 (3):. doi: 10.1111/cmi.12671. PubMed PMID:27665309 .

Search PubMed

2016

  1. Ulman, V, Svoboda, D, Nykter, M, Kozubek, M, Ruusuvuori, P. Virtual cell imaging: A review on simulation methods employed in image cytometry. Cytometry A. 2016;89 (12):1057-1072. doi: 10.1002/cyto.a.23031. PubMed PMID:27922735 .
  2. Huttunen, M, Turkki, P, Mäki, A, Paavolainen, L, Ruusuvuori, P, Marjomäki, V et al.. Echovirus 1 internalization negatively regulates epidermal growth factor receptor downregulation. Cell Microbiol. 2017;19 (3):. doi: 10.1111/cmi.12671. PubMed PMID:27665309 .
  3. Ruusuvuori, P, Valkonen, M, Nykter, M, Visakorpi, T, Latonen, L. Feature-based analysis of mouse prostatic intraepithelial neoplasia in histological tissue sections. J Pathol Inform. 2016;7 :5. doi: 10.4103/2153-3539.175378. PubMed PMID:26955503 PubMed Central PMC4763506.
  4. Hassan, SS, Ruusuvuori, P, Latonen, L, Huttunen, H. Flow Cytometry-Based Classification in Cancer Research: A View on Feature Selection. Cancer Inform. 2015;14 (Suppl 5):75-85. doi: 10.4137/CIN.S30795. PubMed PMID:27081305 PubMed Central PMC4827794.

Search PubMed

2015

  1. Annala, M, Kivinummi, K, Tuominen, J, Karakurt, S, Granberg, K, Latonen, L et al.. Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer. Oncotarget. 2015;6 (8):6235-50. doi: 10.18632/oncotarget.3359. PubMed PMID:25749039 PubMed Central PMC4467434.
  2. Hassan, SS, Ruusuvuori, P, Latonen, L, Huttunen, H. Flow Cytometry-Based Classification in Cancer Research: A View on Feature Selection. Cancer Inform. 2015;14 (Suppl 5):75-85. doi: 10.4137/CIN.S30795. PubMed PMID:27081305 PubMed Central PMC4827794.

Search PubMed