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Prostate Cancer Research Center

Faculty of Medicine and Health Technology

Computational Systems Biology

2020

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2019

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2018

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2017

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2016

  1. Emmert-Streib, F, Dehmer, M, Yli-Harja, O. Against Dataism and for Data Sharing of Big Biomedical and Clinical Data with Research Parasites. Front Genet. 2016;7 :154. doi: 10.3389/fgene.2016.00154. PubMed PMID:27630666 PubMed Central PMC5005320.
  2. Doan, P, Karjalainen, A, Chandraseelan, JG, Sandberg, O, Yli-Harja, O, Rosholm, T et al.. Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines. Eur J Med Chem. 2016;120 :296-303. doi: 10.1016/j.ejmech.2016.05.024. PubMed PMID:27214140 .
  3. Emmert-Streib, F, Tuomisto, L, Yli-Harja, O. The Need for Formally Defining “Modern Medicine” by Means of Experimental Design. Front Genet. 2016;7 :60. doi: 10.3389/fgene.2016.00060. PubMed PMID:27148357 PubMed Central PMC4837140.
  4. Viswanathan, A, Anufrieva, O, Sala, A, Yli-Harja, O, Kandhavelu, M. Phase-dependent dynamics of the lac promoter under nutrient stress. Res Microbiol. 2016;167 (6):451-61. doi: 10.1016/j.resmic.2016.04.002. PubMed PMID:27106257 .

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2015

  1. Ylipää, A, Kivinummi, K, Kohvakka, A, Annala, M, Latonen, L, Scaravilli, M et al.. Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer. Cancer Res. 2015;75 (19):4026-31. doi: 10.1158/0008-5472.CAN-15-0217. PubMed PMID:26282172 .
  2. Sala, A, Shoaib, M, Anufrieva, O, Mutharasu, G, Jahan Hoque, R, Yli-Harja, O et al.. Transcription closed and open complex dynamics studies reveal balance between genetic determinants and co-factors. Phys Biol. 2015;12 (3):036003. doi: 10.1088/1478-3975/12/3/036003. PubMed PMID:25988584 .
  3. Yli-Hietanen, J, Ylipää, A, Yli-Harja, O. Cancer research in the era of next-generation sequencing and big data calls for intelligent modeling. Chin J Cancer. 2015;34 (10):423-6. doi: 10.1186/s40880-015-0008-8. PubMed PMID:25963029 PubMed Central PMC4593335.
  4. Oliveira, SM, Chandraseelan, JG, Häkkinen, A, Goncalves, NS, Yli-Harja, O, Startceva, S et al.. Single-cell kinetics of a repressilator when implemented in a single-copy plasmid. Mol Biosyst. 2015;11 (7):1939-45. doi: 10.1039/c5mb00012b. PubMed PMID:25923804 .
  5. Annala, M, Kivinummi, K, Tuominen, J, Karakurt, S, Granberg, K, Latonen, L et al.. Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer. Oncotarget. 2015;6 (8):6235-50. doi: 10.18632/oncotarget.3359. PubMed PMID:25749039 PubMed Central PMC4467434.
  6. Turner, KM, Sun, Y, Ji, P, Granberg, KJ, Bernard, B, Hu, L et al.. Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression. Proc Natl Acad Sci U S A. 2015;112 (11):3421-6. doi: 10.1073/pnas.1414573112. PubMed PMID:25737557 PubMed Central PMC4371922.
  7. Sala, A, Shoaib, M, Anufrieva, O, Mutharasu, G, Yli-Harja, O, Kandhavelu, M et al.. Origins of transcriptional transition: balance between upstream and downstream regulatory gene sequences. mBio. 2015;6 (1):. doi: 10.1128/mBio.02182-14. PubMed PMID:25626902 PubMed Central PMC4324307.
  8. Viswanathan, A, Sala, A, Yli-Harja, O, Kandhavelu, M. Antimicrobial activity and molecular analysis of azoderivatives of β-diketones. Eur J Pharm Sci. 2015;66 :83-9. doi: 10.1016/j.ejps.2014.09.020. PubMed PMID:25312345 .

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