Computational Systems Biology

2020

  1. Emmert-Streib, F, Yli-Harja, O, Dehmer, M. Artificial Intelligence: A Clarification of Misconceptions, Myths and Desired Status. Front Artif Intell. 2020;3 :524339. doi: 10.3389/frai.2020.524339. PubMed PMID:33733197 PubMed Central PMC7944138.
  2. Viswanathan, A, Musa, A, Murugesan, A, Vale, JR, Afonso, CAM, Mani, SK et al.. Erratum: Viswanathan, A., et al. Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation). 2019, , 1624. Cells. 2020;9 (12):. doi: 10.3390/cells9122631. PubMed PMID:33297601 PubMed Central PMC7762400.
  3. Mutharasu, G, Murugesan, A, Konda Mani, S, Yli-Harja, O, Kandhavelu, M. Transcriptomic analysis of glioblastoma multiforme providing new insights into GPR17 signaling communication. J Biomol Struct Dyn. 2022;40 (6):2586-2599. doi: 10.1080/07391102.2020.1841029. PubMed PMID:33140689 .
  4. Murugesan, A, Holmstedt, S, Brown, KC, Koivuporras, A, Macedo, AS, Nguyen, N et al.. Design and synthesis of novel quinic acid derivatives: cytotoxicity and anticancer effect on glioblastoma. Future Med Chem. 2020;12 (21):1891-1910. doi: 10.4155/fmc-2020-0194. PubMed PMID:33124467 .
  5. Manjang, K, Tripathi, S, Yli-Harja, O, Dehmer, M, Emmert-Streib, F. Graph-based exploitation of gene ontology using GOxploreR for scrutinizing biological significance. Sci Rep. 2020;10 (1):16672. doi: 10.1038/s41598-020-73326-3. PubMed PMID:33028846 PubMed Central PMC7542435.
  6. Palanivel, S, Murugesan, A, Subramanian, K, Yli-Harja, O, Kandhavelu, M. Antiproliferative and apoptotic effects of indole derivative, N-(2-hydroxy-5-nitrophenyl (4′-methylphenyl) methyl) indoline in breast cancer cells. Eur J Pharmacol. 2020;881 :173195. doi: 10.1016/j.ejphar.2020.173195. PubMed PMID:32446710 .
  7. Palanivel, S, Murugesan, A, Yli-Harja, O, Kandhavelu, M. Anticancer activity of THMPP: Downregulation of PI3K/ S6K1 in breast cancer cell line. Saudi Pharm J. 2020;28 (4):495-503. doi: 10.1016/j.jsps.2020.02.015. PubMed PMID:32273810 PubMed Central PMC7132829.
  8. Doan, P, Musa, A, Murugesan, A, Sipilä, V, Candeias, NR, Emmert-Streib, F et al.. Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways. Cells. 2020;9 (3):. doi: 10.3390/cells9030681. PubMed PMID:32164385 PubMed Central PMC7140667.
  9. Palanivel, S, Yli-Harja, O, Kandhavelu, M. Alkylamino Phenol Derivative Induces Apoptosis by Inhibiting EGFR Signaling Pathway in Breast Cancer Cells. Anticancer Agents Med Chem. 2020;20 (7):809-819. doi: 10.2174/1871520620666200213101407. PubMed PMID:32053080 .
  10. Yang, Z, Dehmer, M, Yli-Harja, O, Emmert-Streib, F. Combining deep learning with token selection for patient phenotyping from electronic health records. Sci Rep. 2020;10 (1):1432. doi: 10.1038/s41598-020-58178-1. PubMed PMID:31996705 PubMed Central PMC6989657.

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2019

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2018

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2017

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2016

  1. Emmert-Streib, F, Dehmer, M, Yli-Harja, O. Against Dataism and for Data Sharing of Big Biomedical and Clinical Data with Research Parasites. Front Genet. 2016;7 :154. doi: 10.3389/fgene.2016.00154. PubMed PMID:27630666 PubMed Central PMC5005320.
  2. Doan, P, Karjalainen, A, Chandraseelan, JG, Sandberg, O, Yli-Harja, O, Rosholm, T et al.. Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines. Eur J Med Chem. 2016;120 :296-303. doi: 10.1016/j.ejmech.2016.05.024. PubMed PMID:27214140 .
  3. Emmert-Streib, F, Tuomisto, L, Yli-Harja, O. The Need for Formally Defining “Modern Medicine” by Means of Experimental Design. Front Genet. 2016;7 :60. doi: 10.3389/fgene.2016.00060. PubMed PMID:27148357 PubMed Central PMC4837140.
  4. Viswanathan, A, Anufrieva, O, Sala, A, Yli-Harja, O, Kandhavelu, M. Phase-dependent dynamics of the lac promoter under nutrient stress. Res Microbiol. 2016;167 (6):451-61. doi: 10.1016/j.resmic.2016.04.002. PubMed PMID:27106257 .

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2015

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