Team Members
members
Nonappa Nonappa
- Associate Professor
- Material Chemistry, specifically Nanochemistry
- Faculty of Engineering and Natural Sciences
- Tampere University
- +358504728897
- nonappa@tuni.fi
About me
I am a passionate researcher, dedicated teacher, and inspiring mentor. I have a diverse background spanning multiple fields, including organic and supramolecular chemistry, nanoparticle self-assembly, cryogenic transmission electron microscopy, and extracellular matrix design for breast cancer tissue culture. I am leading a multidisciplinary team of researchers at the interface of materials science and biomedical sciences. We focus on efficiently controlling the structure and properties with the highest possible precision. We develop Lab-on-a-chip-based sustainable in vitro preclinical models for personalized and precision breast cancer disease and diagnostic platforms. We fabricate bio-based short-distance optical fibers and microlasers in the optics and photonics areas. Beyond material development, we are actively engaged in advanced electron microscopy imaging, including cryogenic transmission electron microscopy (Cryo-TEM), electron tomography, and in situ electron microscopy. For more information, see our Research Page and Publications.
Field of expertise
- Bio-based materials for optics and photonics
- Breast cancer disease and diagnostic models
- Precision nanomaterials
- Advanced transmission electron microscopy
Research unit
Material Science and Environmental Engineering
Research career
Current position
- 03.08.2020-Present: Associate Professor (tenure track) in Nanochemistry, Faculty of Engineering and Natural Sciences, Tampere University, Tampere, Finland.
Academic degrees and titles
- 19.10.2018: Abilitazione Scientifica Nationale (ASN), CHIM/07-Fondamenti Chimici delle Tecnologie, MIUR, Italy.
- 26.05.2017: Title of Docent in Soft Matter Microscopy, School of Science, Department of Applied Physics, Aalto University, Finland
- 13.12.2008: Ph.D. in Organic Chemistry, Department of Organic Chemistry, Indian Institute of Science, Bangalore, India.
- 24.05.2003: Master of Science (M.Sc. in Chemistry), Department of Chemistry, Mangalore University, Karnataka, India.
- 19.06.2001: Bachelor of Science (B.Sc. in Chemistry, Botany, and Pharmacognosy as equal options), Shri Dharmasthala Manjunatheshwara College, Ujire, Karnataka, India.
- 10.11.2020: Executive Master of Business Administration, Quantic School of Business and Technology, Washington D.C., USA.
- 04.05.2019: Fundamentals of Business, Quantic School of Business and Technology, Washington D.C., USA
Previous research experience
- 26.05.2017-31.07.2020: Research Fellow and Docent, Department of Applied Physics, School of Science, Aalto University, Finland
- 01.08.2012-25.05.2017: Postdoctoral Researcher, Department of Applied Physics, School of Science, Aalto University, Finland.
- 15.02.2009-31.07.2012: Postdoctoral Researcher, Department of Chemistry, University of Jyväskylä, Finland.
- 15.08.2008-14.02.2009: Visiting Ph.D. student, SITRA fellowship, Department of Chemistry, University of Jyväskylä, Finland
- 23.09.2007-22.03.2008: Visiting Ph.D. student, CIMO fellowship, Department of Chemistry, University of Jyväskylä, Finland
Visit our research group page for more details: https://research.tuni.fi/png/
- Bioinspired Functionally Graded Composite Assembled Using Cellulose Nanocrystals and Genetically Engineered Proteins with Controlled Biomineralization. P.Mohammadi, J.-A. Gandier, Nonappa, W. Wagermaier, A. Miserez, M. Penttilä, Adv. Mater. 2021, 33, 2102658 [Link]
- Luminescent Gold Nanocluster‐Methylcellulose Composite Optical Fibers with Low Attenuation Coefficient and High Photostability. V. Hynninen, S. Chandra, S. Das, M. Amini, Y. Dai, S. Lepikko, P. Mohammadi, S. Hietala, R. H. A. Ras, Z. Sun, O. Ikkala, Nonappa, Small 2021, 17, 2005205 [Link]
- Nanocellulose: Recent fundamental advances and emerging biological and biomimicking applications. K. Heise, E. Kontturi, Y, Allahverdiyeva, T. Tammelin, M. B. Linder, Nonappa, O. Ikkala. Adv. Mater. 2021, 2004349 [Link].
- DNA Origami Templated Growth of Multilamellar Lipid Assemblies. S. Julin, Nonappa, B. Shen V. Linko M. A. Kostiainen, Angewandte. Chem. Intl. Ed. 2021. [Link]
- Luminescent gold nanoclusters for bioimaging applications. Nonappa, Beil. J. Nanotechnol. 2020, 11, 533–546 [Link].
- Atomically Precise Nanocluster Assemblies Encapsulating Plasmonic Gold Nanorods, A. Chakraborty, A. C. Fernandez, A. Som, B. Mondal, G. Natarajan, G. Paramasivam, T. Lahtinen, H. Häkkinen, Nonappa, T. Pradeep. Angew. Chem. Int. Ed. 2018, 57, 6522-6526 [Link].
- Polymer Nanowires with Highly Precise Internal Morphology and Topography, Théophile Pelras, Clare S Mahon, Nonappa, Olli Ikkala, André H Gröschel, Markus Müllner, J. Am. Chem. Soc. 2018, 140, 12736-12740 [Link]
- Hydrogen bonding directed colloidal self-assembly of nanoparticles into 2D crystals, capsids, and supracolloidal assemblies. Nonappa, O. Ikkala, Adv. Funct. Mater. 2018, 28, 1704328 [Link].
- Reversible supracolloidal self-assembly of cobalt nanoparticles to capsids and superstructures. Nonappa, J. S. Haataja, J. V. I Timonen, S. Malola, P. Engelhardt, N. Houbenov, M. Lahtinen, H. Häkkinen, O. Ikkala, Angew. Chem. Int. Ed. 2017, 56, 6473-6477 [Link].
- Template-free supracolloidal self-assembly of atomically precise gold nanoclusters: From 2D colloidal crystals to spherical capsids. Nonappa, T. Lahtinen, J. S. Haataja, T. –R. Tero, H. Häkkinen, O. Ikkala, Angew. Chem. Int. Ed. 2016, 55, 16035–16038 [Link].
Accelerated Engineering of ELP-Based Materials through Hybrid Biomimetic-De Novo Predictive Molecular Design
Laakko, T., Korkealaakso, A., Yildirir, B. F., Batys, P., Liljeström, V., Hokkanen, A., Nonappa, Penttilä, M., Laukkanen, A., Miserez, A., Södergård, C. & Mohammadi, P., 11 heinäk. 2024, julkaisussa: Advanced Materials. 36, 28, 2312299.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Golden Plasmophores with Tunable Photoluminescence and Outstanding Thermal and Photothermal Stability
Gharib, M., Yates, A. J., Sanders, S., Gebauer, J., Graf, S., Ziefuß, A. R., Nonappa, Kassier, G., Rehbock, C., Barcikowski, S., Weller, H., Alabastri, A., Nordlander, P., Parak, W. J. & Chakraborty, I., toukok. 2024, julkaisussa: Advanced Optical Materials. 12, 14, 2302833.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Guided Heterostructure Growth of CoFe LDH on Ti3C2Tx MXene for Durably High Oxygen Evolution Activity
Sheng, J., Kang, J., Jiang, P., Meinander, K., Hong, X., Jiang, H., Nonappa, Ikkala, O., Komsa, H. P., Peng, B. & Lv, Z. P., 2024, (E-pub ahead of print) julkaisussa: Small.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
In situ size dynamics and manipulation of nanoparticle interaction under electron beam irradiation
Zulfiqar, A., Honkanen, M., Vippola, M. & Nonappa, N., 17 lokak. 2024, The 17th European Microscopy Congress (EMC 2024). Qvortrup, K. & Weede, K. (toim.). EDP Sciences, 3 Sivumäärä 08012. (BIO Web of Conferences; Vuosikerta 129).Tutkimustuotos: Konferenssiartikkeli › Tieteellinen
In Situ TEM Imaging Reveals the Dynamic Interplay Between Attraction, Repulsion and Sequential Attraction-Repulsion in Gold Nanoparticles
Zulfiqar, A., Honkanen, M., Nonappa & Vippola, M., 2024, (E-pub ahead of print) julkaisussa: Small.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Interparticle Antigalvanic Reactions of Atomically Precise Silver Nanoclusters with Plasmonic Gold Nanoparticles: Interfacial Control of Atomic Exchange
Bose, P., Roy, J., Khokhar, V., Mondal, B., Natarajan, G., Manna, S., Yadav, V., Nyayban, A., Yamijala, S. S. R. K. C., Nonappa & Pradeep, T., 2024, julkaisussa: Chemistry of Materials. 36, 15, s. 7581-7594Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Invasion/chemotaxis- and extravasation-chip models for breast cancer bone metastasis
Firatligil-Yildirir, B., Bati-Ayaz, G., Nonappa, Pesen-Okvur, D. & Yalcin-Ozuysal, O., lokak. 2024, julkaisussa: PLoS ONE. 19, 10, e0309285.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Mechanically Robust Biopolymer Optical Fibers with Enhanced Performance in the Near-Infrared Region
Patrakka, J., Hynninen, V., Lahtinen, M., Hokkanen, A., Orelma, H., Sun, Z. & Nonappa, N., 14 elok. 2024, julkaisussa: ACS Applied Materials and Interfaces. 16, 32, s. 42704-42716 13 SivumääräTutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Nanocluster reaction-driven in situ transformation of colloidal nanoparticles to mesostructures
Bose, P., Srikrishnarka, P., Paatelainen, M., Nonappa, N., Kini, A. R., Som, A. & Pradeep, T., 2024, (E-pub ahead of print) julkaisussa: Nanoscale.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Platinum-Grafted Twenty-Five Atom Gold Nanoclusters for Robust Hydrogen Evolution
Mymoona, P., Rival, J. V., Nonappa, Shibu, E. S. & Jeyabharathi, C., 2024, julkaisussa: Small. 20, 23, 2308610.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Burcu Firatligil Yildirir
- Postdoctoral Research Fellow
- Faculty of Engineering and Natural Sciences
- Tampere University
- burcu.firatligilyildirir@tuni.fi
About me
In my current role as a postdoctoral researcher in the Precision Nanomaterials Group, I have been working on breast cancer metastasis and developing different 3D culture models to understand how breast cancer initiates and how and why its organ-specific metastasis develops.
In addition to focusing on research, I actively train and supervise students from diverse backgrounds for their bachelor`s (BSc) and master's (MSc) theses.
Field of expertise
I have over 10 years of experience developing 3D in vitro models and microfluidic platforms to identify molecular, mechanical and biochemical changes promoting the formation of breast cancer metastasis using cell, tissue and patient-derived samples.
I use my expertise in in situ contactless rheology to create dynamically responsive soft materials that model breast cancer tissue at both primary sites and secondary metastatic target sites, taking into account not only the genomic events in individual cancer cells but also the composition of the surrounding environment.
Firatligil-Yildirir, B., Bati-Ayaz, G., Nonappa, Pesen-Okvur, D., & Yalcin-Ozuysal, O. (2024). Invasion/Chemotaxis- and Extravasation-chip models for breast cancer bone metastasis. PLOS ONE.
Laakko, T., Korkealaakso, A., Yildirir, B. F., Batys, P., Liljeström, V., Hokkanen, A., Nonappa, N., Penttilä, M., Laukkanen, A., Miserez, A., Södergård, C., & Mohammadi, P. (2024). Accelerated Engineering of ELP‐based Materials through Hybrid Biomimetic‐De Novo Predictive Molecular Design. Advanced Materials.
Firatligil-Yildirir, B., Yalcin-Ozuysal, O., & Nonappa, N. (2023). Recent advances in lab-on-a-chip systems for breast cancer metastasis research. Nanoscale Advances.
Firatligil‐Yildirir, B., Bati‐Ayaz, G., Tahmaz, I., Bilgen, M., Pesen‐Okvur, D., & Yalcin‐Ozuysal, O. (2021). On‐chip determination of tissue‐specific metastatic potential of breast cancer cells. Biotechnology and Bioengineering.
Sarigil, O., Anil‐Inevi, M., Firatligil‐Yildirir, B., Unal, Y. C., Yalcin‐Ozuysal, O., Mese, G., Tekin, H. C., & Ozcivici, E. (2020). Scaffold‐free biofabrication of adipocyte structures with magnetic levitation. Biotechnology and Bioengineering.
Ilhan, M., Kucukkose, C., Efe, E., Gunyuz, Z. E., Firatligil, B., Dogan, H., Ozuysal, M., & Yalcin-Ozuysal, O. (2020). Pro-metastatic functions of Notch signaling is mediated by CYR61 in breast cells. European Journal of Cell Biology.
Srikrishnarka Pillalamarri
- Postdoctoral Research Fellow
- Faculty of Engineering and Natural Sciences
- Tampere University
- +358503367687
- srikrishnarka.pillalamarri@tuni.fi
Field of expertise
Experience in the fabrication of sensors, and expertise in electrospinning for various applications such as face masks, surface coatings, and substrates for cell culture. Hands-on with various optical and electron microscopes (SEM) and used high-speed cameras for various experiments.
Tampere Institute for Advanced study post doctoral fellow (2024-2026)
Towards the fabrication of frugal wearable sensors for health monitoring
Nanocluster reaction-driven in situ transformation of colloidal nanoparticles to mesostructures
Bose, P., Srikrishnarka, P., Paatelainen, M., Nonappa, N., Kini, A. R., Som, A. & Pradeep, T., 2024, (E-pub ahead of print) julkaisussa: Nanoscale.Tutkimustuotos: Artikkeli › Tieteellinen › vertaisarvioitu
Wearable Sensors for Physiological Condition and Activity Monitoring
Srikrishnarka, P., Haapasalo, J., Hinestroza, J. P., Sun, Z. & Nonappa, heinäk. 2024, julkaisussa: Small Science. 4, 7, 2300358.Tutkimustuotos: Katsausartikkeli › vertaisarvioitu
Paulami Bose
- Postdoctoral Research Fellow
- Faculty of Engineering and Natural Sciences
- Tampere University
- +358503440470
- paulami.bose@tuni.fi
Jani Patrakka
- Doctoral Researcher
- Faculty of Engineering and Natural Sciences
- Tampere University
- +358504215234
- jani.patrakka@tuni.fi
Parvin Najafi Anamaghi
- Researcher
- Faculty of Engineering and Natural Sciences
- Tampere University
- parvin.najafianamaghi@tuni.fi
Mea Nevanranta
- Research Assistant
- Faculty of Engineering and Natural Sciences
- Tampere University
- mea.nevanranta@tuni.fi
Laura Sammalisto
- Student Advisor
- Education and Learning
- Tampere University
- +358505961433
- laura.a.sammalisto@tuni.fi
Matias Paatelainen
- Doctoral Researcher
- Faculty of Engineering and Natural Sciences
- Tampere University
- matias.paatelainen@tuni.fi
Abid Zulfiqar
- väitöskirjatutkija
- Tekniikan ja luonnontieteiden tiedekunta
- Tampereen yliopisto
- +358504659566
- abid.zulfiqar@tuni.fi