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VACCIM

Research Center for Vaccine Development and Immunology

Publications

2025

  1. Martinón-Torres, F, Simko, R, Ebert, R, Rämet, M, Zocchetti, C, Syrkina, O et al.. Five-Year Immune Persistence of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) and Immunogenicity and Safety of a Booster Dose in Children. Infect Dis Ther. 2025; :. doi: 10.1007/s40121-025-01121-6. PubMed PMID:40169489 .
  2. Soppela, S, Plavec, Z, Gröhn, S, Mustonen, I, Jartti, M, Oikarinen, S et al.. Immunological and structural evaluation of the intranasally administrated CVB1 whole-virus and VLP vaccines. Sci Rep. 2025;15 (1):10198. doi: 10.1038/s41598-025-94656-0. PubMed PMID:40133550 PubMed Central PMC11937443.
  3. Laiho, JE, Oikarinen, S, Morfopoulou, S, Oikarinen, M, Renner, A, Depledge, D et al.. Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes. Diabetologia. 2025; :. doi: 10.1007/s00125-025-06359-w. PubMed PMID:40095061 .
  4. Rodriguez-Calvo, T, Laiho, JE, Oikarinen, M, Akhbari, P, Flaxman, C, Worthington, T et al.. Enterovirus VP1 protein and HLA class I hyperexpression in pancreatic islet cells of organ donors with type 1 diabetes. Diabetologia. 2025; :. doi: 10.1007/s00125-025-06384-9. PubMed PMID:40090995 .
  5. Richardson, SJ, Rodriguez-Calvo, T, Laiho, JE, Kaddis, JS, Nyalwidhe, JO, Kusmartseva, I et al.. Joint analysis of the nPOD-Virus Group data: the association of enterovirus with type 1 diabetes is supported by multiple markers of infection in pancreas tissue. Diabetologia. 2025; :. doi: 10.1007/s00125-025-06401-x. PubMed PMID:40090994 .
  6. Vecchio, F, Laiho, JE, Hyoty, H, Pugliese, A, Mallone, R. Comment on Manduchi et al. No Evidence for Persistent Enteroviral B Infection of Pancreatic Islets in Patients With Type 1 Diabetes and Prediabetes From RNA Sequencing Data. Diabetes 2024;73:1697-1704. Diabetes. 2025;74 (3):e3-e4. doi: 10.2337/db24-0809. PubMed PMID:39977614 .
  7. Roshanbinfar, K, Evans, AD, Samanta, S, Kolesnik-Gray, M, Fiedler, M, Krstic, V et al.. Enhancing biofabrication: Shrink-resistant collagen-hyaluronan composite hydrogel for tissue engineering and 3D bioprinting applications. Biomaterials. 2025;318 :123174. doi: 10.1016/j.biomaterials.2025.123174. PubMed PMID:39951830 .
  8. Walsh, EE, Eiras, D, Woodside, J, Jiang, Q, Patton, M, Marc, GP et al.. Efficacy, Immunogenicity, and Safety of the Bivalent RSV Prefusion F (RSVpreF) Vaccine in Older Adults Over 2 RSV Seasons. Clin Infect Dis. 2025; :. doi: 10.1093/cid/ciaf061. PubMed PMID:39928572 .
  9. Hummel, S, Käßl, A, Arnolds, S, Achenbach, P, Berner, R, Casteels, K et al.. Anti-viral action against type 1 diabetes autoimmunity: The GPPAD-AVAnT1A study protocol. Contemp Clin Trials Commun. 2025;44 :101434. doi: 10.1016/j.conctc.2025.101434. PubMed PMID:39916680 PubMed Central PMC11799962.
  10. Uusi-Mäkelä, M, Harjula, SE, Junno, M, Sillanpää, A, Nätkin, R, Niskanen, MT et al.. The inflammasome adaptor pycard is essential for immunity against Mycobacterium marinum infection in adult zebrafish. Dis Model Mech. 2025;18 (9):. doi: 10.1242/dmm.052061. PubMed PMID:39916610 PubMed Central PMC11972081.
  11. Koski, S, Martinon-Torres, F, Rämet, M, Zolotas, L, Newton, R, Maansson, R et al.. A Phase 3B, Open-Label Study to Evaluate the Immunogenicity and Safety of the Quadrivalent Meningococcal Nimenrix Vaccine When Given to Healthy Infants at 3 and 12 Months of Age. Infect Dis Ther. 2025;14 (2):463-481. doi: 10.1007/s40121-024-01098-8. PubMed PMID:39883399 PubMed Central PMC11829884.
  12. Mynarek, IM, Krogvold, L, Mørk, FB, Lawaetz, TWH, Roald, T, Fagerland, MW et al.. Three-Year Follow-up After Antiviral Treatment in New-Onset Type 1 Diabetes: Results From the Diabetes Virus Detection and Intervention Trial. Diabetes Care. 2025;48 (3):481-488. doi: 10.2337/dc24-2121. PubMed PMID:39804800 .
  13. Juusola, T, Aho-Laukkanen, E, Rahkonen, M, Mäki-Koivisto, V, Junttila, IS. Cryptococcal meningoencephalitis in a patient on immunomodulatory drug: A case report. J Mycol Med. 2025;35 (1):101529. doi: 10.1016/j.mycmed.2024.101529. PubMed PMID:39756269 .
  14. Virtanen, A, Kettunen, V, Musta, K, Räkköläinen, V, Knapp, S, Haikarainen, T et al.. Molecular basis of JAK kinase regulation guiding therapeutic approaches: Evaluating the JAK3 pseudokinase domain as a drug target. Adv Biol Regul. 2025;95 :101072. doi: 10.1016/j.jbior.2024.101072. PubMed PMID:39755448 .
  15. Loponen, J, Vähätalo, I, Tuomisto, LE, Niemelä, O, Lehtimäki, L, Hämäläinen, M et al.. Physical exercise, systemic inflammation and adult-onset asthma: a 12-year follow-up study. J Asthma. 2025;62 (4):714-724. doi: 10.1080/02770903.2024.2438096. PubMed PMID:39636329 .
  16. Savolainen, LE, Peltola, J, Hilla, R, Åman, T, Broas, M, Junttila, IS et al.. Clinical performance of two commercially available rapid antigen tests for influenza, RSV, and SARS-CoV-2 diagnostics. Microbiol Spectr. 2025;13 (1):e0163024. doi: 10.1128/spectrum.01630-24. PubMed PMID:39589150 PubMed Central PMC11705943.
  17. Lernmark, Å, Agardh, D, Akolkar, B, Gesualdo, P, Hagopian, WA, Haller, MJ et al.. Looking back at the TEDDY study: lessons and future directions. Nat Rev Endocrinol. 2025;21 (3):154-165. doi: 10.1038/s41574-024-01045-0. PubMed PMID:39496810 PubMed Central PMC11825287.
  18. Marttila, S, Rajić, S, Ciantar, J, Mak, JKL, Junttila, IS, Kummola, L et al.. Biological aging of different blood cell types. Geroscience. 2025;47 (1):1075-1092. doi: 10.1007/s11357-024-01287-w. PubMed PMID:39060678 PubMed Central PMC11872950.
  19. Jonsdottir, B, Clasen, JL, Vehik, K, Lernmark, Å, Lundgren, M, Bonifacio, E et al.. Early Appearance of Thyroid Autoimmunity in Children Followed From Birth for Type 1 Diabetes Risk. J Clin Endocrinol Metab. 2025;110 (2):498-510. doi: 10.1210/clinem/dgae478. PubMed PMID:38996042 PubMed Central PMC11747670.
  20. Madhi, SA, Ceballos, A, Cousin, L, Domachowske, JB, Langley, JM, Lu, E et al.. Population Attributable Risk of Wheeze in 2-<6-Year-old Children, Following a Respiratory Syncytial Virus Lower Respiratory Tract Infection in The First 2 Years of Life. Pediatr Infect Dis J. 2025; :. doi: 10.1097/INF.0000000000004447. PubMed PMID:38985986 .

Search PubMed

2024

  1. Juusola, T, Aho-Laukkanen, E, Rahkonen, M, Mäki-Koivisto, V, Junttila, IS. Cryptococcal meningoencephalitis in a patient on immunomodulatory drug: A case report. J Mycol Med. 2025;35 (1):101529. doi: 10.1016/j.mycmed.2024.101529. PubMed PMID:39756269 .
  2. Virtanen, A, Kettunen, V, Musta, K, Räkköläinen, V, Knapp, S, Haikarainen, T et al.. Molecular basis of JAK kinase regulation guiding therapeutic approaches: Evaluating the JAK3 pseudokinase domain as a drug target. Adv Biol Regul. 2025;95 :101072. doi: 10.1016/j.jbior.2024.101072. PubMed PMID:39755448 .
  3. Nolan, T, Bhusal, C, Beran, J, Bloch, M, Cetin, BS, Dinleyici, EC et al.. Breadth of immune response, immunogenicity, reactogenicity, and safety for a pentavalent meningococcal ABCWY vaccine in healthy adolescents and young adults: results from a phase 3, randomised, controlled observer-blinded trial. Lancet Infect Dis. 2024; :. doi: 10.1016/S1473-3099(24)00667-4. PubMed PMID:39647494 .
  4. Loponen, J, Vähätalo, I, Tuomisto, LE, Niemelä, O, Lehtimäki, L, Hämäläinen, M et al.. Physical exercise, systemic inflammation and adult-onset asthma: a 12-year follow-up study. J Asthma. 2024; :1-11. doi: 10.1080/02770903.2024.2438096. PubMed PMID:39636329 .
  5. Savolainen, LE, Peltola, J, Hilla, R, Åman, T, Broas, M, Junttila, IS et al.. Clinical performance of two commercially available rapid antigen tests for influenza, RSV, and SARS-CoV-2 diagnostics. Microbiol Spectr. 2025;13 (1):e0163024. doi: 10.1128/spectrum.01630-24. PubMed PMID:39589150 PubMed Central PMC11705943.
  6. Hyöty, H, Laiho, JE, Virtanen, SM. Environmental Factors in Type 1 Diabetes. Cold Spring Harb Perspect Med. 2024; :. doi: 10.1101/cshperspect.a041590. PubMed PMID:39586629 .
  7. Nolan, T, Bhusal, C, Beran, J, Bloch, M, Cetin, BS, Dinleyici, EC et al.. 4CMenB Breadth of Immune Response, Immunogenicity, and Safety: Results From a Phase 3 Randomized, Controlled, Observer Blind Study in Adolescents and Young Adults. Open Forum Infect Dis. 2024;11 (11):ofae638. doi: 10.1093/ofid/ofae638. PubMed PMID:39582508 PubMed Central PMC11584413.
  8. Tavast, IM, Solismaa, A, Lyytikäinen, LP, Mononen, N, Moilanen, E, Hämäläinen, M et al.. Leptin and leptin receptor gene polymorphisms and depression treatment response. Acta Neuropsychiatr. 2024; :1-8. doi: 10.1017/neu.2024.43. PubMed PMID:39529327 .
  9. Lernmark, Å, Agardh, D, Akolkar, B, Gesualdo, P, Hagopian, WA, Haller, MJ et al.. Looking back at the TEDDY study: lessons and future directions. Nat Rev Endocrinol. 2025;21 (3):154-165. doi: 10.1038/s41574-024-01045-0. PubMed PMID:39496810 PubMed Central PMC11825287.
  10. Kedari, A, Iheozor-Ejiofor, R, Salminen, P, Uğurlu, H, Mäkelä, AR, Levanov, L et al.. Structural insight into rabies virus neutralization revealed by an engineered antibody scaffold. Structure. 2024;32 (12):2220-2230.e4. doi: 10.1016/j.str.2024.10.002. PubMed PMID:39471803 .
  11. Eurén, A, Lynch, K, Lindfors, K, Parikh, H, Koletzko, S, Liu, E et al.. Risk of celiac disease autoimmunity is modified by interactions between CD247 and environmental exposures. Sci Rep. 2024;14 (1):25463. doi: 10.1038/s41598-024-75496-w. PubMed PMID:39462122 PubMed Central PMC11567144.
  12. Lampinen, V, Ojanen, MJT, Caro, FM, Gröhn, S, Hankaniemi, MM, Pesu, M et al.. Experimental VLP vaccine displaying a furin antigen elicits production of autoantibodies and is well tolerated in mice. Nanoscale Adv. 2024;6 (24):6239-52. doi: 10.1039/d4na00483c. PubMed PMID:39430302 PubMed Central PMC11485048.
  13. Walsh, EE, Pérez Marc, G, Falsey, AR, Jiang, Q, Eiras, D, Patton, M et al.. RENOIR Trial – RSVpreF Vaccine Efficacy over Two Seasons. N Engl J Med. 2024;391 (15):1459-1460. doi: 10.1056/NEJMc2311560. PubMed PMID:39413383 .
  14. Suonsyrjä, N, Metso, S, Moilanen, E, Mustonen, J, Jaatinen, P, Pörsti, I et al.. Haemodynamics of hyperthyroidism: increased cardiac work and findings related to vasodilatation. Eur Thyroid J. 2024;13 (5):. doi: 10.1530/ETJ-24-0090. PubMed PMID:39356807 PubMed Central PMC11558968.
  15. Pemmari, A, Moilanen, E. Macrophage and chondrocyte phenotypes in inflammation. Basic Clin Pharmacol Toxicol. 2024;135 (5):537-549. doi: 10.1111/bcpt.14085. PubMed PMID:39319534 .
  16. Laiho, JE, Oikarinen, S, Morfopoulou, S, Oikarinen, M, Renner, A, Depledge, D et al.. Detection of enterovirus RNA in pancreas and lymphoid tissues of organ donors with type 1 diabetes. medRxiv. 2024; :. doi: 10.1101/2024.09.11.24313112. PubMed PMID:39314969 PubMed Central PMC11419248.
  17. Parajuli, A, Mäkelä, I, Roslund, MI, Ringqvist, E, Manninen, J, Sun, Y et al.. Production, analysis, and safety assessment of a soil and plant-based natural material with microbiome- and immune-modulatory effects. Methods. 2024;231 :94-102. doi: 10.1016/j.ymeth.2024.09.011. PubMed PMID:39306218 .
  18. Pasanen, A, Karjalainen, MK, Korppi, M, Hallman, M, Rämet, M, Research Project FinnGen
    et al.. Genetic susceptibility to acute viral bronchiolitis. J Infect Dis. 2024; :. doi: 10.1093/infdis/jiae467. PubMed PMID:39299705 .
  19. Atomwise AIMS Program. Author Correction: AI is a viable alternative to high throughput screening: a 318-target study. Sci Rep. 2024;14 (1):21579. doi: 10.1038/s41598-024-70321-w. PubMed PMID:39284864PubMed Central PMC11405665.
  20. Ojwang’, V, Nwaru, BI, Hanna-Mari, T, Heli, T, Kaila, M, Ahonen, S et al.. Early-pregnancy BMI, maternal gestational weight gain, and asthma and allergic diseases in children. Pediatr Allergy Immunol. 2024;35 (9):e14240. doi: 10.1111/pai.14240. PubMed PMID:39282918 .
  21. Virtanen, A, Spinelli, FR, Telliez, JB, O’Shea, JJ, Silvennoinen, O, Gadina, M et al.. JAK inhibitor selectivity: new opportunities, better drugs?. Nat Rev Rheumatol. 2024;20 (10):649-665. doi: 10.1038/s41584-024-01153-1. PubMed PMID:39251770 .
  22. Langley, JM, Nolan, TM, Rämet, M, Richmond, PC, Rosário Filho, N, Haazen, W et al.. A Phase 1/2a Study Evaluating Safety and Immunogenicity of Ad26.RSV.preF in RSV-seronegative Toddlers Aged 12-24 Months. Open Forum Infect Dis. 2024;11 (9):ofae453. doi: 10.1093/ofid/ofae453. PubMed PMID:39220658 PubMed Central PMC11365064.
  23. Wang, X, Baster, Z, Azizi, L, Li, L, Rajfur, Z, Hytönen, VP et al.. Talin2 binds to non-muscle myosin IIa and regulates cell attachment and fibronectin secretion. Sci Rep. 2024;14 (1):20175. doi: 10.1038/s41598-024-70866-w. PubMed PMID:39215026 PubMed Central PMC11364542.
  24. Turkki, P, Chowdhury, I, Öhman, T, Azizi, L, Varjosalo, M, Hytönen, VP et al.. Tensin-2 interactomics reveals interaction with GAPDH and a phosphorylation-mediated regulatory role in glycolysis. Sci Rep. 2024;14 (1):19862. doi: 10.1038/s41598-024-65787-7. PubMed PMID:39191795 PubMed Central PMC11350193.
  25. Azizi, L, Otani, Y, Mykuliak, VV, Goult, BT, Hytönen, VP, Turkki, P et al.. Talin-1 variants associated with spontaneous coronary artery dissection (SCAD) highlight how even subtle changes in multi-functional scaffold proteins can manifest in disease. Hum Mol Genet. 2024;33 (21):1846-1857. doi: 10.1093/hmg/ddae120. PubMed PMID:39163585 PubMed Central PMC11540920.
  26. Sallomy, C, Awolade, P, Rahnasto-Rilla, M, Hämäläinen, M, Nousiainen, LP, Johansson, NG et al.. TRPA1 Inhibition Effects by 3-Phenylcoumarin Derivatives. ACS Med Chem Lett. 2024;15 (8):1221-1226. doi: 10.1021/acsmedchemlett.4c00072. PubMed PMID:39140042 PubMed Central PMC11318103.
  27. Tiensuu, H, Haapalainen, AM, Tissarinen, P, Pasanen, A, Hallman, M, Rämet, M et al.. MicroRNA expression profile in the basal plate of human placenta associates with spontaneous preterm birth. Placenta. 2024;155 :60-69. doi: 10.1016/j.placenta.2024.08.004. PubMed PMID:39137705 .
  28. Roslund, MI, Nurminen, N, Oikarinen, S, Puhakka, R, Grönroos, M, Puustinen, L et al.. Skin exposure to soil microbiota elicits changes in cell-mediated immunity to pneumococcal vaccine. Sci Rep. 2024;14 (1):18573. doi: 10.1038/s41598-024-68235-8. PubMed PMID:39127736 PubMed Central PMC11316737.
  29. Bizaki-Vallaskangas, A, Rämö, J, Sliz, E, Kivekäs, I, Willberg, T, Saarentaus, E et al.. Genome-wide association study indicates novel associations of annexin A13 to secretory and GAS2L2 with mucous otitis media. Sci Rep. 2024;14 (1):18344. doi: 10.1038/s41598-024-68781-1. PubMed PMID:39112560PubMed Central PMC11306868.
  30. Mykuliak, VV, Rahikainen, R, Ball, NJ, Bussi, G, Goult, BT, Hytönen, VP et al.. Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force. PLoS Comput Biol. 2024;20 (8):e1012341. doi: 10.1371/journal.pcbi.1012341. PubMed PMID:39110765 PubMed Central PMC11333002.
  31. Clark, R, Davies, S, Labrador, J, Loubet, P, Natalini Martínez, S, Moríñigo, HM et al.. Safety and Immunogenicity of Respiratory Syncytial Virus Prefusion F Protein Vaccine when Co-administered with Adjuvanted Seasonal Quadrivalent Influenza Vaccine in Older Adults: A Phase 3 Randomized Trial. Clin Infect Dis. 2024;79 (4):1088-1098. doi: 10.1093/cid/ciae365. PubMed PMID:39099085 PubMed Central PMC11478588.
  32. Marttila, S, Rajić, S, Ciantar, J, Mak, JKL, Junttila, IS, Kummola, L et al.. Biological aging of different blood cell types. Geroscience. 2025;47 (1):1075-1092. doi: 10.1007/s11357-024-01287-w. PubMed PMID:39060678 PubMed Central PMC11872950.
  33. Jartti, M, Flodström-Tullberg, M, Hankaniemi, MM. Enteroviruses: epidemic potential, challenges and opportunities with vaccines. J Biomed Sci. 2024;31 (1):73. doi: 10.1186/s12929-024-01058-x. PubMed PMID:39010093 PubMed Central PMC11247760.
  34. Ryyti, R, Hämäläinen, M, Tolonen, T, Mäki, M, Jaakkola, M, Peltola, R et al.. Lingonberry (- L.) Skin Extract Prevents Weight Gain and Hyperglycemia in High-Fat Diet-Induced Model of Obesity in Mice. Nutrients. 2024;16 (13):. doi: 10.3390/nu16132107. PubMed PMID:38999854 PubMed Central PMC11243352.
  35. Madhi, SA, Ceballos, A, Cousin, L, Domachowske, JB, Langley, JM, Lu, E et al.. Population Attributable Risk of Wheeze in 2-<6-Year-old Children, Following a Respiratory Syncytial Virus Lower Respiratory Tract Infection in The First 2 Years of Life. Pediatr Infect Dis J. 2024; :. doi: 10.1097/INF.0000000000004447. PubMed PMID:38985986 .
  36. Soppela, S, Plavec, Z, Gröhn, S, Jartti, M, Oikarinen, S, Laajala, M et al.. Comparison of structure and immunogenicity of CVB1-VLP and inactivated CVB1 vaccine candidates. Res Sq. 2024; :. doi: 10.21203/rs.3.rs-4545395/v1. PubMed PMID:38978565 PubMed Central PMC11230480.
  37. Lampinen, V, Gröhn, S, Lehmler, N, Jartti, M, Hytönen, VP, Schubert, M et al.. Production of norovirus-, rotavirus-, and enterovirus-like particles in insect cells is simplified by plasmid-based expression. Sci Rep. 2024;14 (1):14874. doi: 10.1038/s41598-024-65316-6. PubMed PMID:38937523 PubMed Central PMC11211442.
  38. Niinistö, S, Cuthbertson, D, Miettinen, ME, Hakola, L, Nucci, A, Korhonen, TE et al.. High Concentrations of Immunoglobulin G Against Cow Milk Proteins and Frequency of Cow Milk Consumption Are Associated With the Development of Islet Autoimmunity and Type 1 Diabetes-The Trial to Reduce Insulin-dependent Diabetes Mellitus (IDDM) in the Genetically at Risk (TRIGR) Study. J Nutr. 2024;154 (8):2493-2500. doi: 10.1016/j.tjnut.2024.06.005. PubMed PMID:38906178 PubMed Central PMC11375457.
  39. Sidibé, A, Mykuliak, VV, Zhang, P, Hytönen, VP, Wu, J, Wehrle-Haller, B et al.. Acetyl-NPKY of integrin-β1 binds KINDLIN2 to control endothelial cell proliferation and junctional integrity. iScience. 2024;27 (6):110129. doi: 10.1016/j.isci.2024.110129. PubMed PMID:38904068 PubMed Central PMC11187247.
  40. Hakola, L, Lund-Blix, NA, Takkinen, HM, Tapanainen, H, Niinistö, S, Korhonen, TE et al.. Maternal gluten, cereal, and dietary fiber intake during pregnancy and lactation and the risk of islet autoimmunity and type 1 diabetes in the child. Clin Nutr ESPEN. 2024;62 :22-27. doi: 10.1016/j.clnesp.2024.05.001. PubMed PMID:38901945 .
  41. Goswami, J, Baqui, AH, Doreski, PA, Perez Marc, G, Jimenez, G, Ahmed, S et al.. Humoral Immunogenicity of mRNA-1345 RSV Vaccine in Older Adults. J Infect Dis. 2024;230 (5):e996-e1006. doi: 10.1093/infdis/jiae316. PubMed PMID:38889247 PubMed Central PMC11566230.
  42. Miao, Y, Virtanen, A, Zmajkovic, J, Hilpert, M, Skoda, RC, Silvennoinen, O et al.. Functional and Structural Characterization of Clinical-Stage Janus Kinase 2 Inhibitors Identifies Determinants for Drug Selectivity. J Med Chem. 2024;67 (12):10012-10024. doi: 10.1021/acs.jmedchem.4c00197. PubMed PMID:38843875PubMed Central PMC11215726.
  43. Evans, AD, Pournoori, N, Saksala, E, Oommen, OP. Glycosaminoglycans’ for brain health: Harnessing glycosaminoglycan based biomaterials for treating central nervous system diseases and in-vitro modeling. Biomaterials. 2024;309 :122629. doi: 10.1016/j.biomaterials.2024.122629. PubMed PMID:38797120 .
  44. Salo, TE, Hakola, L, Niinistö, S, Takkinen, HM, Ahonen, S, Puustinen, L et al.. Gut Inflammation Markers, Diet, and Risk of Islet Autoimmunity in Finnish Children – A Nested Case-Control Study. J Nutr. 2024;154 (7):2244-2254. doi: 10.1016/j.tjnut.2024.05.015. PubMed PMID:38795745 PubMed Central PMC11282497.
  45. Tissarinen, P, Tiensuu, H, Haapalainen, AM, Ronkainen, E, Laatio, L, Vääräsmäki, M et al.. Maternal serum alpha-1 antitrypsin levels in spontaneous preterm and term pregnancies. Sci Rep. 2024;14 (1):10819. doi: 10.1038/s41598-024-61206-z. PubMed PMID:38734716 PubMed Central PMC11088650.
  46. Starskaia, I, Valta, M, Pietilä, S, Suomi, T, Pahkuri, S, Kalim, UU et al.. Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies. Nat Commun. 2024;15 (1):3810. doi: 10.1038/s41467-024-47918-w. PubMed PMID:38714671 PubMed Central PMC11076468.
  47. Saarenpää, M, Roslund, MI, Nurminen, N, Puhakka, R, Kummola, L, Laitinen, OH et al.. Urban indoor gardening enhances immune regulation and diversifies skin microbiota – A placebo-controlled double-blinded intervention study. Environ Int. 2024;187 :108705. doi: 10.1016/j.envint.2024.108705. PubMed PMID:38688234 .
  48. Leclerc, S, Gupta, A, Ruokolainen, V, Chen, JH, Kunnas, K, Ekman, AA et al.. Progression of herpesvirus infection remodels mitochondrial organization and metabolism. PLoS Pathog. 2024;20 (4):e1011829. doi: 10.1371/journal.ppat.1011829. PubMed PMID:38620036 PubMed Central PMC11045090.
  49. Atomwise AIMS Program. AI is a viable alternative to high throughput screening: a 318-target study. Sci Rep. 2024;14 (1):7526. doi: 10.1038/s41598-024-54655-z. PubMed PMID:38565852 PubMed Central PMC10987645.
  50. Meinhardt, A, Reilly, L, Kaliakatsos, M, Abdel-Aziz, K, Alsharidah, S, Bodi, I et al.. Novel antivirals for severe enterovirus infection in immunocompromised hosts; A case series. J Infect. 2024;88 (5):106142. doi: 10.1016/j.jinf.2024.106142. PubMed PMID:38527653 .
  51. Mäenpää, N, Tiainen, L, Hämäläinen, M, Luukkaala, T, Tanner, M, Lahdenperä, O et al.. Neuropilin-1 and placental growth factor as prognostic factors in metastatic breast cancer. BMC Cancer. 2024;24 (1):331. doi: 10.1186/s12885-024-12070-7. PubMed PMID:38468231 PubMed Central PMC10929217.
  52. Abraham, BG, Haikarainen, T, Vuorio, J, Girych, M, Virtanen, AT, Kurttila, A et al.. Molecular basis of JAK2 activation in erythropoietin receptor and pathogenic JAK2 signaling. Sci Adv. 2024;10 (10):eadl2097. doi: 10.1126/sciadv.adl2097. PubMed PMID:38457493 PubMed Central PMC10923518.
  53. Vecchio, F, Carré, A, Korenkov, D, Zhou, Z, Apaolaza, P, Tuomela, S et al.. Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 T cell responses. Sci Adv. 2024;10 (10):eadl1122. doi: 10.1126/sciadv.adl1122. PubMed PMID:38446892 PubMed Central PMC10917340.
  54. Lehtola, T, Nummenmaa, E, Nieminen, R, Hämäläinen, M, Vuolteenaho, K, Moilanen, E et al.. The glucocorticoid dexamethasone alleviates allergic inflammation through a mitogen-activated protein kinase phosphatase-1-dependent mechanism in mice. Basic Clin Pharmacol Toxicol. 2024;134 (5):686-694. doi: 10.1111/bcpt.13995. PubMed PMID:38439200 .
  55. Savijoki, K, Deptula, P, Roberts, RJ, Hammarén, M, Yli-Kauhaluoma, J, Varmanen, P et al.. Revised whole genome and DNA methylome of type strain ATCC 927. Microbiol Resour Announc. 2024;13 (4):e0101623. doi: 10.1128/mra.01016-23. PubMed PMID:38415640 PubMed Central PMC11008211.
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Search PubMed

2022

  1. Koskela, K, Sauni, R, Uitti, J, Oksa, P, Moilanen, E, Hämäläinen, M et al.. An Increase in Plasma Adipsin Levels Is Associated With Higher Cumulative Dust Exposure and Airway Obstruction in Foundry Workers. J Occup Environ Med. 2023;65 (3):203-209. doi: 10.1097/JOM.0000000000002736. PubMed PMID:36730948 .
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  5. Ryyti, R, Hämäläinen, M, Leppänen, T, Peltola, R, Moilanen, E. Phenolic Compounds Known to Be Present in Lingonberry ( L.) Enhance Macrophage Polarization towards the Anti-Inflammatory M2 Phenotype. Biomedicines. 2022;10 (12):. doi: 10.3390/biomedicines10123045. PubMed PMID:36551801 PubMed Central PMC9776286.
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