Previous projects

Cell and Tissue Engineering

Human Spare Parts, 2011-2019

The goal of this project was to develop stem cell-based solutions and advanced in vitro models for neural, cardiac, bone, and adipose diseases and traumas. The project combined top-level expertise in biomaterials, sensor technology, biomedical engineering and stem cells to develop technologies and solutions for new therapies and drug treatments while reducing the use of laboratory animals. Alltogether 8 research groups from Tampere Universities participated in the project that produced several in vitro models and led to several national New Businesses from Research Ideas –projects aiming at the commercialization of the developed solutions.

WoodBone

The goal of the project was to study multi-parametric in-situ monitoring of paper fibers and osteogenic cells while they experience chemical and mechanical stimuli. The monitored parameters were internal morphological structures and their mechanical properties. We proposed a microrobotic approach which does not only provide a sufficient throughput but also a possibility to respond to the changes in the measured parameters by modifying the stimulation parameters and thus, to control the material properties, for example in osteogenic differentiation.

Mini-Hypoxy

This Tekes funded TUTLi project developed technology for portable hypoxia environment and investigated its commercial potential.

Neuro TUTL

This Tekes funded TUTLi project developed technology for in vitro neuro models and investigated their commercial potential.

BioRA

The project focused on the staff exchange between the partners of EU and China, and on the development of new technologies and applications in the field of biomedical robotics on the macro, micro and nano scales for biological cell detection, manipulation, test and injection. The project included five participants from Europe (UK, Finland, Germany, Bulgaria) and five from China.

DrugPermeA

This Tekes funded project developed a novel and versatile microfluidic in vitro alternative for tissue permeability studies.

FIBAM

The project developed new methods to better understand the properties of wood derived fibers and muscle fibers in a human heart. The approach in the project was to use microrobotics, i.e automatic instruments which can precisely manipulate and measure properties of individual microscopic objects.

Stemfunc

Biomimetic Active Environment for Maturing and Differentiating Stem Cells (2008-2011)

OPTIMI

Optically Actuated Microfluidics (2007-2009)

DAAD-NANO

Nanorobot-based electrical and mechanical characterization of biological cells (2007-2009)

PICO

Development of Control Methods for Piezoelectric Actuators (2003-2008). Development of control Methods for Piezoelectric Actuators (2003-2008)

ACC

Automated Cell Culturing on a Well Plate (2003-2007)

LIVD

Development of Methods for Testing of Therapeutic Molecules In-vitro (2004-2006)

GENOMANDA

Automatic Manipulation, Detection and Analysis of Functions of Genes (2004-2005)

AIM

Integration of Automatic Intracellular Microinjection and Bioelectrical Recordings (2003-2004)

SOLOMANDA

Automatic Manipulation, Detection and Analysis of Individual Biological Cells (2000-2002).

 

Material characterization and microassembly

FibRobotics

The project studied characterization of fibre reinforced materials at micro scale using microrobotics.

WoodBone

The goal of the project was to study multi-parametric in-situ monitoring of paper fibers and osteogenic cells while they experience chemical and mechanical stimuli. The monitored parameters were internal morphological structures and their mechanical properties. We proposed a microrobotic approach which does not only provide a sufficient throughput but also a possibility to respond to the changes in the measured parameters by modifying the stimulation parameters and thus, to control the material properties, for example in osteogenic differentiation.

BioRA

The project focused on the staff exchange between the partners of EU and China, and on the development of new technologies and applications in the field of biomedical robotics on the macro, micro and nano scales for biological cell detection, manipulation, test and injection. The project included five participants from Europe (UK, Finland, Germany, Bulgaria) and five from China.

PowerBonds

The WoodWisdom-Net project aimed to increase the understanding of paper strength. The strength of paper is largely dependent on the properties of individual paper fibres and inter-fibre bonds. If the strength of bonds or fibres can be improved, paper manufacturers will be able replace expensive fibres with cheaper fillers, such as chalk and clay. The project studied fibre strength and bonding capabilities using novel mechanical and chemical fibre modifications and by developing new models and characterization tools. TUT focused on the development of microrobotic methods to automatically characrerize the stregth of individual fibre bonds. http://www.youtube.com/user/ttytutase

FIBAM

The project developed new methods to better understand the properties of wood derived fibers and muscle fibers in a human heart. The approach in the project is to use microrobotics, i.e automatic instruments which can precisely manipulate and measure properties of individual microscopic objects.

ECNANOMAN

The project was a part of International Research Staff Exchange Programme (IRSES) in FP7. The goal was to establish a long-term research cooperation platform between Europe and China. The objective was achieved by means of staff exchange between the partners of EU and China in the areas of nano handling, assembly and manufacturing technologies. The project included four participants from Europe (Germany, Finland, Denmark, France) and five from China.

FiFiBo

New Insights into Fibre-Fibre Bonding using Micro- and Nanorobotic Technologies. The goal of this researcher mobility project was to develop and deploy novel micro- and nanorobotic techniques to increase the understanding of the bonding and de-bonding of cellulose fibres. The project put together robotic expertise in two scales: microrobotic paper fiber expertise at Tampere University of Technology and nanorobotic expertise at the University of Oldenburg.

SmartFibre

Surface Engineering of Pulp Fibres: New Functionalisation Concepts for Smart Fibre Products (2009-2011)

FPMC

Flow Process Management and Control (2006-2010)

MELA

MEMS Laminates Technologies (2003-2004)

ROBOSEM

Development of a Smart Nanorobot for Sensor-Based Handling in a Scanning Electron Microscope (2002-2004)

FEMAS

Future Electronic Microassembly Systems (2001-2002)

PAMIR

Treatment of Paper Fibers using Microsystem Technology (2000-2002)

TOMI – µASSY

Towards mini and microassembly (2000-2002)

VR-MICRO

Virtual Environment for Operation in the Micro World (1997-1999)

AMINU

Advanced Microsystems – Collaboration with Nagoya University (1999)

 

Point of Care Diagnostics and Microfluidics

Digits

Digital Scents (2016-2017). DIGITS research project aimed to develop a system prototype which measures scents by an electric nose (eNose) and digitizes them. The scents could then be reproduced by using a self-learning scent synthesiser. Our role in the project was to develop the scent synthesizer using microfluidics and machine learning methods.

ReDia

Ready-to-use Microfluidic Cartridges for Affordable Point-of-care Diagnostics. The objective of this collaborative Finnish-Indian project was to develop rapid tests for the detection of heart infraction and tuberculosis. ASE develops automatic microfluidic technologies for on-chip liquid handling.

NucleoTracker

Tracking Nucleic Acid Containing Compounds in Water Environment, 2010-2012
The objective of the project was to develop methods for measuring nucleic acid containing analytes in water resources. The analytes can be either biological organisms or synthetic compounds added advisedly to water. ASE developed disposable microfluidic chips for liquid handling.

NanoFlow

Enhancement of in vitro Diagnostics using Nanoparticle Labels, Nanophotonics and Microfluidics (2008-2011)

PanFlow

Microfluidics Platform for a Multi-purpose Point-of-use need System (2005-2008)

BIOAKUSTI

Microacoustic Biosensor (2006-2009)

NEOPOC

Total Analysis System for POC Diagnostics (2004-2005)

MIFLUS

Microfluidics Survey (2003-2004)

BLOSD

Development of an Automatic Blood Sampling Device (2002-2003)

FLUISY

Development of Microfluidic Systems  (1997-1999)