In 2008, professor Andre S. Ribeiro started a research group, the Laboratory of Biosystem Dynamics at Tampere University, Finland, to study the in vivo dynamics and regulatory mechanisms of bacterial gene expression, from single genes up to large-scale circuits. The LBD uses a single-cell approach supported by time-lapse microscopy, flow-cytometry, RNA-seq, and synthetic gene engineering, along with multi-scale stochastic models and methods from network theory and signal processing.
Our aim is to understand how structure and dynamics of bacterial gene networks relate, to find new strategies for how to disrupt or stimulate them that, in the long-term, can contribute to therapeutical and biotechnological efforts.
Professor Andre S. Ribeiro has a degree in physics from the University of Lisbon, followed by a Ph.D. in network theory at the Technical University of Lisbon, Portugal. He then was a postdoctoral research fellow at the University of Calgary in Canada, where he developed large scale stochastic models of gene networks.